Cd209e (CD209e molecule) - Rat Genome Database

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Gene: Cd209e (CD209e molecule) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Cd209e
Name: CD209e molecule
RGD ID: 1563333
Description: Predicted to enable D-mannose binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in Coronavirus infectious disease; aspergillosis; dengue disease (multiple); human immunodeficiency virus infectious disease (multiple); and tuberculosis (multiple). Orthologous to human CD209 (CD209 molecule); PARTICIPATES IN measles pathway; phagocytosis pathway; tuberculosis pathway.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CD209 antigen-like protein E; CD209e antigen; LOC501797; RGD1563333; similar to SIGNR4
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8126,661,179 - 6,666,634 (-)NCBIGRCr8
mRatBN7.2121,862,104 - 1,868,735 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,863,279 - 1,868,735 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx122,535,929 - 2,541,378 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0123,159,499 - 3,164,948 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,922,246 - 1,927,695 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,381,378 - 2,387,960 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,382,475 - 2,387,930 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,534,744 - 4,541,289 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,312,144 - 2,317,599 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera123,716,946 - 3,722,401 (-)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Cd209e
15 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:136
Count of miRNA genes:108
Interacting mature miRNAs:116
Transcripts:ENSRNOT00000031997
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12136247923Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)127977298525593Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 5 8 17 28 40 10 25 10 6 75 44 7 9 13 30

Sequence


Ensembl Acc Id: ENSRNOT00000031997   ⟹   ENSRNOP00000029615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,863,279 - 1,868,735 (-)Ensembl
Rnor_6.0 Ensembl122,382,475 - 2,387,930 (-)Ensembl
RefSeq Acc Id: NM_001192005   ⟹   NP_001178934
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,661,179 - 6,666,634 (-)NCBI
mRatBN7.2121,863,279 - 1,868,735 (-)NCBI
Rnor_6.0122,382,475 - 2,387,930 (-)NCBI
Rnor_5.0124,534,744 - 4,541,289 (-)NCBI
Celera123,716,946 - 3,722,401 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178934 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL74967 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000029615.3
RefSeq Acc Id: NP_001178934   ⟸   NM_001192005
- UniProtKB: D3ZCF3 (UniProtKB/TrEMBL),   A6KQ42 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029615   ⟸   ENSRNOT00000031997
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZCF3-F1-model_v2 AlphaFold D3ZCF3 1-207 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563333 AgrOrtholog
BioCyc Gene G2FUF-20378 BioCyc
Ensembl Genes ENSRNOG00000028803 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031997.5 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/TrEMBL
InterPro C-type_lectin UniProtKB/TrEMBL
  C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin_CS UniProtKB/TrEMBL
  C-type_lectin_fold UniProtKB/TrEMBL
  C-type_Lectin_Receptor_IMM UniProtKB/TrEMBL
  CD209-like_CTLD UniProtKB/TrEMBL
KEGG Report rno:501797 UniProtKB/TrEMBL
NCBI Gene 501797 ENTREZGENE
PANTHER CD209 ANTIGEN-LIKE PROTEIN C-LIKE UniProtKB/TrEMBL
  KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY F MEMBER 2 UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/TrEMBL
PhenoGen Cd209e PhenoGen
PROSITE C_TYPE_LECTIN_1 UniProtKB/TrEMBL
  C_TYPE_LECTIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028803 RatGTEx
SMART CLECT UniProtKB/TrEMBL
Superfamily-SCOP C-type_lectin_fold UniProtKB/TrEMBL
UniProt A6KQ42 ENTREZGENE, UniProtKB/TrEMBL
  D3ZCF3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-06-27 Cd209e  CD209e molecule  Cd209e  CD209e antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Cd209e  CD209e antigen  RGD1563333_predicted  similar to SIGNR4 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563333_predicted  similar to SIGNR4 (predicted)  LOC501797  similar to SIGNR4  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501797  similar to SIGNR4      Symbol and Name status set to provisional 70820 PROVISIONAL