Lamb3 (laminin subunit beta 3) - Rat Genome Database

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Gene: Lamb3 (laminin subunit beta 3) Rattus norvegicus
Analyze
Symbol: Lamb3
Name: laminin subunit beta 3
RGD ID: 1562668
Description: Predicted to be involved in several processes, including basement membrane assembly; endodermal cell differentiation; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within brown fat cell differentiation. Predicted to be located in basement membrane. Predicted to be part of laminin-5 complex. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1A; junctional epidermolysis bullosa; and lung small cell carcinoma. Orthologous to human LAMB3 (laminin subunit beta 3); PARTICIPATES IN cell-extracellular matrix signaling pathway; Entamoebiasis pathway; small cell lung carcinoma pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: laminin chain; laminin subunit beta-3; laminin, beta 3; LOC305078
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813107,362,514 - 107,404,081 (+)NCBIGRCr8
GRCr8 Ensembl13107,322,526 - 107,404,081 (+)EnsemblGRCr8 Ensembl
mRatBN7.213104,833,810 - 104,875,405 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13104,833,873 - 104,875,405 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13107,351,461 - 107,392,990 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,735,317 - 108,776,855 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013105,953,273 - 105,994,797 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013112,031,614 - 112,073,187 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13112,031,594 - 112,073,186 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,587,097 - 116,628,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413109,148,815 - 109,190,322 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13104,263,258 - 104,304,743 (+)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
3,4-dichloroaniline  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
azathioprine  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
cefaloridine  (EXP)
celastrol  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
fentanyl  (EXP)
fipronil  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
furfural  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
ketoconazole  (EXP)
L-methionine  (ISO)
lamivudine  (ISO)
lead diacetate  (ISO)
lysophosphatidylcholine  (ISO)
methotrexate  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
N-ethyl-N-nitrosourea  (ISO)
nickel sulfate  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
pentane-2,3-dione  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
resveratrol  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sphingosine 1-phosphate  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
tetrathiomolybdate(2-)  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triazines  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Differential expression of the LAMB3 and LAMC2 genes between small cell and non-small cell lung carcinomas. Manda R, etal., Biochem Biophys Res Commun. 2000 Aug 28;275(2):440-5. doi: 10.1006/bbrc.2000.3331.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. A homozygous nonsense mutation in the beta 3 chain gene of laminin 5 (LAMB3) in Herlitz junctional epidermolysis bullosa. Pulkkinen L, etal., Genomics. 1994 Nov 15;24(2):357-60.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Epigenetic inactivation of laminin-5-encoding genes in lung cancers. Sathyanarayana UG, etal., Clin Cancer Res. 2003 Jul;9(7):2665-72.
11. Laminin alpha 5, a major transcript of normal and malignant rat liver epithelial cells, is differentially expressed in developing and adult liver. Seebacher T, etal., Exp Cell Res 1997 Nov 25;237(1):70-6.
12. Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes. Yan HH and Cheng CY, J Biol Chem. 2006 Jun 23;281(25):17286-303. Epub 2006 Apr 11.
Additional References at PubMed
PMID:8012114   PMID:9264260   PMID:18492766   PMID:18757743   PMID:20039268   PMID:20301201   PMID:23154389  


Genomics

Comparative Map Data
Lamb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813107,362,514 - 107,404,081 (+)NCBIGRCr8
GRCr8 Ensembl13107,322,526 - 107,404,081 (+)EnsemblGRCr8 Ensembl
mRatBN7.213104,833,810 - 104,875,405 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13104,833,873 - 104,875,405 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13107,351,461 - 107,392,990 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,735,317 - 108,776,855 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013105,953,273 - 105,994,797 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013112,031,614 - 112,073,187 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13112,031,594 - 112,073,186 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,587,097 - 116,628,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413109,148,815 - 109,190,322 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera13104,263,258 - 104,304,743 (+)NCBICelera
Cytogenetic Map13q27NCBI
LAMB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381209,614,870 - 209,652,425 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1209,614,870 - 209,652,425 (-)EnsemblGRCh38hg38GRCh38
GRCh371209,788,215 - 209,825,770 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361207,854,838 - 207,892,443 (-)NCBINCBI36Build 36hg18NCBI36
Build 341206,176,639 - 206,214,152NCBI
Celera1183,019,124 - 183,056,711 (-)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1180,463,503 - 180,501,095 (-)NCBIHuRef
CHM1_11211,060,621 - 211,098,219 (-)NCBICHM1_1
T2T-CHM13v2.01208,861,637 - 208,900,810 (-)NCBIT2T-CHM13v2.0
Lamb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,976,661 - 193,026,186 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1192,890,007 - 193,026,186 (+)EnsemblGRCm39 Ensembl
GRCm381193,294,353 - 193,343,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1193,207,699 - 193,343,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv371195,128,188 - 195,170,072 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361195,002,753 - 195,044,602 (+)NCBIMGSCv36mm8
Celera1200,179,164 - 200,221,182 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.71NCBI
Lamb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554892,568,650 - 2,607,595 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554892,547,611 - 2,603,079 (+)NCBIChiLan1.0ChiLan1.0
LAMB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2139,740,768 - 39,786,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1139,708,426 - 39,752,535 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,191,401 - 185,245,154 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11189,996,634 - 190,034,206 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1189,996,639 - 190,034,206 (-)Ensemblpanpan1.1panPan2
LAMB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,272,326 - 8,313,322 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,272,736 - 8,310,474 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha77,849,692 - 7,976,332 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.077,973,087 - 8,099,489 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl77,973,113 - 8,012,658 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.177,902,916 - 8,029,231 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.078,000,050 - 8,126,276 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.078,060,953 - 8,187,735 (-)NCBIUU_Cfam_GSD_1.0
Lamb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934466,190,090 - 66,247,713 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365573,450,247 - 3,487,954 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365573,429,488 - 3,487,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9133,311,834 - 133,351,197 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19133,298,009 - 133,351,162 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29146,594,591 - 146,598,263 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAMB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12519,805,234 - 19,856,025 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2519,807,045 - 19,846,684 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605520,402,855 - 20,458,028 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lamb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248072,320,168 - 2,378,349 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:183
Count of miRNA genes:135
Interacting mature miRNAs:157
Transcripts:ENSRNOT00000008440
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
BE101834  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213104,875,181 - 104,875,389 (+)MAPPERmRatBN7.2
Rnor_6.013112,072,964 - 112,073,171NCBIRnor6.0
Rnor_5.013116,628,580 - 116,628,787UniSTSRnor5.0
RGSC_v3.413109,190,099 - 109,190,306UniSTSRGSC3.4
Celera13104,304,520 - 104,304,727UniSTS
RH 3.4 Map13758.4UniSTS
Cytogenetic Map13q27UniSTS
Lamb3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213104,862,155 - 104,862,925 (+)MAPPERmRatBN7.2
Rnor_6.013112,059,938 - 112,060,707NCBIRnor6.0
Rnor_5.013116,615,340 - 116,616,109UniSTSRnor5.0
RGSC_v3.413109,177,073 - 109,177,842UniSTSRGSC3.4
Celera13104,291,494 - 104,292,263UniSTS
Cytogenetic Map13q27UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 11 93 45 60 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000008440   ⟹   ENSRNOP00000008440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13107,362,553 - 107,404,081 (+)Ensembl
mRatBN7.2 Ensembl13104,833,873 - 104,875,405 (+)Ensembl
Rnor_6.0 Ensembl13112,031,594 - 112,073,186 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121167   ⟹   ENSRNOP00000107541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13107,322,526 - 107,404,081 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000122344   ⟹   ENSRNOP00000112201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13107,371,024 - 107,404,081 (+)Ensembl
RefSeq Acc Id: NM_001100841   ⟹   NP_001094311
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813107,362,553 - 107,404,081 (+)NCBI
mRatBN7.213104,833,873 - 104,875,405 (+)NCBI
Rnor_6.013112,031,657 - 112,073,187 (+)NCBI
Rnor_5.013116,587,097 - 116,628,803 (+)NCBI
RGSC_v3.413109,148,815 - 109,190,322 (+)RGD
Celera13104,263,258 - 104,304,743 (+)RGD
Sequence:
RefSeq Acc Id: XM_008769856   ⟹   XP_008768078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813107,362,514 - 107,404,081 (+)NCBI
mRatBN7.213104,833,810 - 104,875,405 (+)NCBI
Rnor_6.013112,031,614 - 112,073,187 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001094311 (Get FASTA)   NCBI Sequence Viewer  
  XP_008768078 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA70094 (Get FASTA)   NCBI Sequence Viewer  
  EDL95035 (Get FASTA)   NCBI Sequence Viewer  
  EDL95036 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008440
  ENSRNOP00000008440.4
  ENSRNOP00000107541
RefSeq Acc Id: NP_001094311   ⟸   NM_001100841
- Peptide Label: precursor
- UniProtKB: F1LPI5 (UniProtKB/TrEMBL),   A6JH29 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768078   ⟸   XM_008769856
- Peptide Label: isoform X1
- UniProtKB: F1LPI5 (UniProtKB/TrEMBL),   A6JH29 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008440   ⟸   ENSRNOT00000008440
Ensembl Acc Id: ENSRNOP00000112201   ⟸   ENSRNOT00000122344
Ensembl Acc Id: ENSRNOP00000107541   ⟸   ENSRNOT00000121167
Protein Domains
Laminin EGF-like   Laminin N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LPI5-F1-model_v2 AlphaFold F1LPI5 1-1172 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699129
Promoter ID:EPDNEW_R9654
Type:initiation region
Name:Lamb3_1
Description:laminin subunit beta 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013112,031,669 - 112,031,729EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562668 AgrOrtholog
BioCyc Gene G2FUF-16784 BioCyc
Ensembl Genes ENSRNOG00000006025 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008440 ENTREZGENE
  ENSRNOT00000008440.7 UniProtKB/TrEMBL
  ENSRNOT00000121167 ENTREZGENE
Gene3D-CATH Galactose-binding domain-like UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  EGF_laminin UniProtKB/TrEMBL
  Laminin/Netrin_ECM UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
KEGG Report rno:305078 UniProtKB/TrEMBL
NCBI Gene 305078 ENTREZGENE
PANTHER LAMININ SUBUNIT BETA-3 UniProtKB/TrEMBL
  NETRIN/LAMININ-RELATED UniProtKB/TrEMBL
Pfam LAMB1 UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
PhenoGen Lamb3 PhenoGen
PRINTS EGFLAMININ UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAMININ_NTER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006025 RatGTEx
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  LamNT UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
UniProt A6JH29 ENTREZGENE, UniProtKB/TrEMBL
  F1LPI5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Lamb3  laminin subunit beta 3  Lamb3  laminin, beta 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Lamb3  laminin, beta 3  LOC305078  laminin chain  Symbol and Name updated 1299863 APPROVED
2006-02-09 LOC305078  laminin chain      Symbol and Name status set to provisional 70820 PROVISIONAL