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Gene: Mterf4 (mitochondrial transcription termination factor 4) Rattus norvegicus

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Symbol:

Mterf4

Name:

mitochondrial transcription termination factor 4

RGD ID:

1562440

Description:

Predicted to enable rRNA binding activity. Predicted to be involved in mitochondrial ribosome assembly and regulation of mitochondrial transcription. Predicted to act upstream of or within several processes, including mitochondrial transcription; protein targeting to mitochondrion; and ribosome assembly. Predicted to be located in cytosol. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrion. Orthologous to human MTERF4 (mitochondrial transcription termination factor 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC363289; MGC112635; MTERF domain containing 2; mTERF domain-containing protein 2; Mterfd2; similar to RIKEN cDNA 1810059A23; transcription termination factor 4, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	101,281,560 - 101,286,236 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	101,281,543 - 101,286,259 (-)	Ensembl				GRCr8
mRatBN7.2	9	93,834,162 - 93,838,838 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	93,834,144 - 93,838,864 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	102,269,722 - 102,274,398 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	107,405,509 - 107,410,186 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	105,761,651 - 105,766,328 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	100,440,482 - 100,445,158 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	100,440,486 - 100,445,158 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	100,096,837 - 100,101,513 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	92,572,064 - 92,576,740 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	91,369,116 - 91,373,792 (-)	NCBI		Celera
Cytogenetic Map	9	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bethlem Myopathy 1A (ISO)

chromosome 2q37 deletion syndrome (ISO)

D-2-hydroxyglutaric aciduria 1 (ISO)

hereditary spastic paraplegia 30 (ISO)

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

17alpha-ethynylestradiol (ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (ISO)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

colforsin daropate hydrochloride (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

enniatin (EXP)

finasteride (EXP)

flutamide (EXP)

gentamycin (EXP)

leflunomide (ISO)

methidathion (ISO)

N-methyl-4-phenylpyridinium (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

sodium arsenite (ISO)

tamoxifen (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

camera-type eye development (IEA,ISO)

heart development (IEA,ISO)

mitochondrial ribosome assembly (IBA,ISO)

mitochondrial transcription (IEA)

protein targeting to mitochondrion (IEA)

regulation of mitochondrial transcription (IBA)

ribosome assembly (IEA)

rRNA processing (IEA)

Cellular Component

cytosol (IEA,ISO)

mitochondrial large ribosomal subunit (IEA)

mitochondrion (IBA,IEA,ISO)

Molecular Function

nucleic acid binding (IEA)

protein binding (ISO)

RNA binding (IEA)

rRNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:21531335

Genomics

Comparative Map Data

Mterf4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	101,281,560 - 101,286,236 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	101,281,543 - 101,286,259 (-)	Ensembl				GRCr8
mRatBN7.2	9	93,834,162 - 93,838,838 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	93,834,144 - 93,838,864 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	102,269,722 - 102,274,398 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	107,405,509 - 107,410,186 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	105,761,651 - 105,766,328 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	100,440,482 - 100,445,158 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	100,440,486 - 100,445,158 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	100,096,837 - 100,101,513 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	92,572,064 - 92,576,740 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	91,369,116 - 91,373,792 (-)	NCBI		Celera
Cytogenetic Map	9	q36	NCBI

MTERF4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	241,042,586 - 241,102,287 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	241,072,169 - 241,102,332 (-)	Ensembl			hg38	GRCh38
GRCh37	2	242,011,583 - 242,041,702 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	241,675,180 - 241,690,397 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	2	235,696,211 - 235,711,450 (-)	NCBI		Celera
Cytogenetic Map	2	q37.3	NCBI
HuRef	2	233,782,517 - 233,797,755 (-)	NCBI		HuRef
CHM1_1	2	242,032,564 - 242,047,803 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	241,539,417 - 241,601,395 (-)	NCBI		T2T-CHM13v2.0

Mterf4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	93,228,927 - 93,233,601 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	93,226,933 - 93,233,637 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	93,301,205 - 93,305,879 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	93,299,211 - 93,305,915 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	95,195,788 - 95,202,447 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	95,129,617 - 95,136,276 (-)	NCBI		MGSCv36	mm8
Celera	1	96,243,881 - 96,250,538 (-)	NCBI		Celera
Cytogenetic Map	1	D	NCBI
cM Map	1	47.24	NCBI

Mterf4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955542	579,356 - 584,508 (+)	Ensembl
ChiLan1.0	NW_004955542	579,183 - 584,617 (+)	NCBI	ChiLan1.0	ChiLan1.0

MTERF4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	143,774,572 - 143,795,662 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	143,789,537 - 143,810,627 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	128,330,967 - 128,362,014 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	247,131,640 - 247,158,239 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	247,128,252 - 247,158,239 (-)	Ensembl			panPan2	panpan1.1

MTERF4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	51,129,186 - 51,144,452 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	51,351,824 - 51,357,081 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	51,333,637 - 51,338,907 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	51,333,638 - 51,338,379 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	51,158,150 - 51,186,619 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	50,920,889 - 50,926,153 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	51,197,133 - 51,202,402 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mterf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	192,509,991 - 192,514,021 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936745	705,448 - 709,429 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MTERF4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	139,881,222 - 139,887,032 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	139,881,217 - 139,887,505 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	154,997,365 - 155,003,731 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MTERF4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	127,145,903 - 127,152,721 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	127,146,466 - 127,152,655 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	72,230,324 - 72,237,126 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mterf4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624847	5,207,882 - 5,214,156 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624847	5,207,624 - 5,214,218 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Mterf4
16 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	55
Count of miRNA genes:	48
Interacting mature miRNAs:	52
Transcripts:	ENSRNOT00000056558
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582203	Gluco19	Glucose level QTL 19	3.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	9	92491589	100929786	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
724547	Cm21	Cardiac mass QTL 21	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	79271511	102910209	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
4889852	Pur26	Proteinuria QTL 26	15	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	77813894	101597663	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat

Markers in Region

AI642697

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	93,833,867 - 93,833,963 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	100,440,188 - 100,440,283	NCBI	Rnor6.0
Rnor_5.0	9	100,096,543 - 100,096,638	UniSTS	Rnor5.0
RGSC_v3.4	9	92,571,770 - 92,571,865	UniSTS	RGSC3.4
Celera	9	91,368,822 - 91,368,917	UniSTS
Cytogenetic Map	9	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001037209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC098676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218478	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000056558 ⟹ ENSRNOP00000053397

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	101,281,548 - 101,286,259 (-)	Ensembl
mRatBN7.2 Ensembl	9	93,834,144 - 93,838,864 (-)	Ensembl
Rnor_6.0 Ensembl	9	100,440,486 - 100,445,158 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000134890 ⟹ ENSRNOP00000107521

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	101,281,543 - 101,285,690 (-)	Ensembl

RefSeq Acc Id:

NM_001037209 ⟹ NP_001032286

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	101,281,560 - 101,286,236 (-)	NCBI
mRatBN7.2	9	93,834,162 - 93,838,838 (-)	NCBI
Rnor_6.0	9	100,440,482 - 100,445,158 (-)	NCBI
Rnor_5.0	9	100,096,837 - 100,101,513 (-)	NCBI
RGSC_v3.4	9	92,572,064 - 92,576,740 (-)	RGD
Celera	9	91,369,116 - 91,373,792 (-)	RGD

Sequence:

show sequence

CATGGCTTCGCTGGGAAGGCAGGTTCCTGAATGGCATCGTCTAATGGCCCTTTCCTGGGCCTGT
TTGGCTAGGCAGACCTGTCATTTCAGAAAAGAGAAAAAGATGAGTCCTTCTTTGTTTTGTAAAC
TGACTACAGTACCCAGTAGAGGGAACTTTCAAGAGTTTTCCAGCGTTAGACCCAAAAAGTACAT
GCAGGAACCAGAACACAGGACACGTCTTGTTCCGTGTCTTCATGAGGAACAGAGGACATGTATG
GGTTCTGAGTCCTTGGAGCTTGAAAGGGCCATCAGTTCCCTCCAGGACATGGGTTTTGCTGAAG
CCCATATTGACAGCTTGCTCAATATACAACCAAGTGTCCATCCTCAACAGTTGCTGGACATAAT
TTCAGAACTTCTACTCTTGGGGTTGAACCCAGAGCCTGTATTTATGGCCTTGAAGAAAAATCCC
CAGTTGCTGAAACTGTCTGCCACGCAAATGAAGAGGCGTTCCAGTTACCTTCGGAAGCTCGGCC
TTGGAGAAGGGAAACTGAAGCGGGTGCTTTCTGTTTGCCCTAAGGTTTTCACCATGCGTCAGCA
GGACATTGATAATATTGTAAAAGTCCTCAAGGAGAAGTGCTTGTTCACAGTACAGCACATCACT
GACATTCTGCACAGATGCCCAGCTGTTTTGCAGGAGGACCCCAGTGAGCTAGAATACAAATTCC
AGTATGCATATTTCAGGATGGGACTGACACATCTAGACATCGTCAGGACCGATTTCCTACAGTA
TTCAATAGCCAAGGTCAAGCAGAGACACATTTACTTGGAGCGCCTTGGACGGTACCAAACCCCT
GATAAGAAGGGGCAGACACAGATCCCTAATCCCTCACTGAAGAACATTCTCAGAGTTTCTGAAG
CTGAGTTTTTGGCCAGGACAGCCTGTTCCTCTGCTGAGGAGTTTGAAGTTTTTAAAAAGCTCTT
GGATCAAGAGGAGGAGGAGTCTGAGAGCCATATGTCTGAGGAGGAGGAGGAGGAAGAGGAAGAA
GAGGAGGAGGAGCTGCCGTGACAGAGCACTGGGATGTCAGAGGTCATTCTCATGTTCCTGAAGC
ACTGGGGAGCTTCACCTGGATCTTCTCAAGCACTTTTGATCCCAACACTGTTTGATAAAGGAAA
AAACAAAAAAACAAAACAAAACAAAAAAACCCCAGCCAACCTGCAGTGATCTACTGGAGATTCA
GGTAAATCCACCAAAGCAAATGAGGGGCTTTTTGAGTTCTGTGGGGGGCCCTACTCCATCCTAA
ATAAAGGACTCAGCTGTCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001032286	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98676	(Get FASTA)	NCBI Sequence Viewer
	EDL91954	(Get FASTA)	NCBI Sequence Viewer
	EDL91955	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000053397
	ENSRNOP00000053397.2
GenBank Protein	Q4G078	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001032286 ⟸ NM_001037209

- UniProtKB:

Q4G078 (UniProtKB/Swiss-Prot), A6JQY2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASLGRQVPEWHRLMALSWACLARQTCHFRKEKKMSPSLFCKLTTVPSRGNFQEFSSVRPKKYM
QEPEHRTRLVPCLHEEQRTCMGSESLELERAISSLQDMGFAEAHIDSLLNIQPSVHPQQLLDII
SELLLLGLNPEPVFMALKKNPQLLKLSATQMKRRSSYLRKLGLGEGKLKRVLSVCPKVFTMRQQ
DIDNIVKVLKEKCLFTVQHITDILHRCPAVLQEDPSELEYKFQYAYFRMGLTHLDIVRTDFLQY
SIAKVKQRHIYLERLGRYQTPDKKGQTQIPNPSLKNILRVSEAEFLARTACSSAEEFEVFKKLL
DQEEEESESHMSEEEEEEEEEEEEELP

hide sequence

Ensembl Acc Id:

ENSRNOP00000053397 ⟸ ENSRNOT00000056558

Ensembl Acc Id:

ENSRNOP00000107521 ⟸ ENSRNOT00000134890

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4G078-F1-model_v2	AlphaFold	Q4G078	1-347	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696872

Promoter ID:

EPDNEW_R7397

Type:

multiple initiation site

Name:

Mterf4_1

Description:

mitochondrial transcription termination factor 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	100,445,181 - 100,445,241	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1562440	AgrOrtholog
BioCyc Gene	G2FUF-26651	BioCyc
Ensembl Genes	ENSRNOG00000037376	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000056558	ENTREZGENE
	ENSRNOT00000056558.5	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.70.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7372734	IMAGE-MGC_LOAD
InterPro	MTERF	UniProtKB/Swiss-Prot
	MTERF_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:363289	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:112635	IMAGE-MGC_LOAD
NCBI Gene	363289	ENTREZGENE
PANTHER	CGI-12 PROTEIN-RELATED	UniProtKB/Swiss-Prot
	TRANSCRIPTION TERMINATION FACTOR 4, MITOCHONDRIAL	UniProtKB/Swiss-Prot
Pfam	mTERF	UniProtKB/Swiss-Prot
PhenoGen	Mterf4	PhenoGen
RatGTEx	ENSRNOG00000037376	RatGTEx
SMART	Mterf	UniProtKB/Swiss-Prot
UniProt	A6JQY2	ENTREZGENE, UniProtKB/TrEMBL
	MTEF4_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-10	Mterf4	mitochondrial transcription termination factor 4	Mterfd2	MTERF domain containing 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Mterfd2	MTERF domain containing 2	LOC363289	similar to RIKEN cDNA 1810059A23	Symbol and Name updated	1299863	APPROVED
2006-02-09	LOC363289	similar to RIKEN cDNA 1810059A23			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar