Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tomm40l | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Tomm40l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TOMM40L mRNA | CTD | PMID:36331819 | Tomm40l | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tomm40l (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TOMM40L mRNA | CTD | PMID:22206623 | Tomm40l | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Tomm40l (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:32352317 | Tomm40l | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19095052 | Tomm40l | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:27291303 | Tomm40l | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tomm40l (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TOMM40L mRNA | CTD | PMID:21354282 | Tomm40l | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Tomm40l (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of TOMM40L exon | CTD | PMID:33297965 | Tomm40l | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Tomm40l (Mus musculus) | 6480464 | bisphenol S affects the methylation of TOMM40L gene | CTD | PMID:31683443 | Tomm40l | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TOMM40L mRNA | CTD | PMID:24780913 | Tomm40l | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TOMM40L mRNA | CTD | PMID:31881176 | Tomm40l | Rat | acrolein | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of TOMM40L mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of TOMM40L mRNA | CTD | PMID:32699268 | Tomm40l | Rat | acrylamide | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of TOMM40L mRNA | CTD | PMID:32763439 | Tomm40l | Rat | aflatoxin B1 | decreases methylation | ISO | TOMM40L (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TOMM40L gene | CTD | PMID:27153756 | Tomm40l | Rat | alpha-pinene | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of TOMM40L mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of TOMM40L mRNA | CTD | PMID:32699268 | Tomm40l | Rat | benzo[a]pyrene | affects methylation | ISO | TOMM40L (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TOMM40L promoter | CTD | PMID:27901495 | Tomm40l | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TOMM40L promoter | CTD | PMID:23359474 | Tomm40l | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TOMM40L promoter | CTD | PMID:23359474 | Tomm40l | Rat | bisphenol A | increases expression | ISO | Tomm40l (Mus musculus) | 6480464 | bisphenol A results in increased expression of TOMM40L mRNA | CTD | PMID:32156529 | Tomm40l | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TOMM40L gene | CTD | PMID:28505145 | Tomm40l | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TOMM40L mRNA | CTD | PMID:25181051 | Tomm40l | Rat | bisphenol F | decreases expression | ISO | Tomm40l (Mus musculus) | 6480464 | bisphenol F results in decreased expression of TOMM40L mRNA | CTD | PMID:38685157 | Tomm40l | Rat | carbamazepine | affects expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Carbamazepine affects the expression of TOMM40L mRNA | CTD | PMID:25979313 | Tomm40l | Rat | copper atom | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TOMM40L mRNA | CTD | PMID:20971185 | Tomm40l | Rat | copper(0) | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TOMM40L mRNA | CTD | PMID:20971185 | Tomm40l | Rat | copper(II) sulfate | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TOMM40L mRNA | CTD | PMID:19549813 | Tomm40l | Rat | cyclosporin A | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TOMM40L mRNA | CTD | PMID:25562108 | Tomm40l | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of TOMM40L mRNA | CTD | PMID:23914054 | Tomm40l | Rat | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TOMM40L promoter | CTD | PMID:23359474 | Tomm40l | Rat | dorsomorphin | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TOMM40L mRNA | CTD | PMID:27188386 | Tomm40l | Rat | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of TOMM40L mRNA | CTD | PMID:34044035 | Tomm40l | Rat | folic acid | multiple interactions | ISO | Tomm40l (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TOMM40L mRNA | CTD | PMID:22206623 | Tomm40l | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of TOMM40L gene | CTD | PMID:22079235 | Tomm40l | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TOMM40L mRNA | CTD | PMID:25539665 | Tomm40l | Rat | furan | increases expression | ISO | Tomm40l (Mus musculus) | 6480464 | furan results in increased expression of TOMM40L mRNA | CTD | PMID:24183702 | Tomm40l | Rat | lead(0) | affects methylation | ISO | TOMM40L (Homo sapiens) | 6480464 | Lead affects the methylation of TOMM40L gene | CTD | PMID:31636367 | Tomm40l | Rat | ozone | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of TOMM40L mRNA more ... | CTD | PMID:32699268 | Tomm40l | Rat | paracetamol | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TOMM40L mRNA | CTD | PMID:21420995 more ... | Tomm40l | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TOMM40L mRNA | CTD | PMID:33387578 | Tomm40l | Rat | parathion | decreases expression | ISO | Tomm40l (Mus musculus) | 6480464 | Parathion results in decreased expression of TOMM40L mRNA | CTD | PMID:34813904 | Tomm40l | Rat | perfluorononanoic acid | increases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of TOMM40L mRNA | CTD | PMID:32588087 | Tomm40l | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tomm40l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TOMM40L mRNA | CTD | PMID:36331819 | Tomm40l | Rat | phenobarbital | affects expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Phenobarbital affects the expression of TOMM40L mRNA | CTD | PMID:19159669 | Tomm40l | Rat | pirinixic acid | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TOMM40L mRNA | CTD | PMID:19710929 | Tomm40l | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Tomm40l (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of TOMM40L mRNA | CTD | PMID:28903501 | Tomm40l | Rat | SB 431542 | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TOMM40L mRNA | CTD | PMID:27188386 | Tomm40l | Rat | sodium arsenite | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TOMM40L mRNA | CTD | PMID:38568856 | Tomm40l | Rat | sodium arsenite | increases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TOMM40L mRNA | CTD | PMID:34032870 | Tomm40l | Rat | sunitinib | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of TOMM40L mRNA | CTD | PMID:31533062 | Tomm40l | Rat | tamoxifen | increases expression | ISO | Tomm40l (Mus musculus) | 6480464 | Tamoxifen results in increased expression of TOMM40L mRNA | CTD | PMID:25123088 | Tomm40l | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TOMM40L mRNA | CTD | PMID:33387578 | Tomm40l | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TOMM40L mRNA | CTD | PMID:34492290 | Tomm40l | Rat | thiram | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Thiram results in decreased expression of TOMM40L mRNA | CTD | PMID:38568856 | Tomm40l | Rat | trichostatin A | affects expression | ISO | TOMM40L (Homo sapiens) | 6480464 | trichostatin A affects the expression of TOMM40L mRNA | CTD | PMID:28542535 | Tomm40l | Rat | urethane | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Urethane results in decreased expression of TOMM40L mRNA | CTD | PMID:28818685 | Tomm40l | Rat | valproic acid | decreases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TOMM40L mRNA | CTD | PMID:29154799 | Tomm40l | Rat | valproic acid | multiple interactions | ISO | TOMM40L (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TOMM40L mRNA | CTD | PMID:27188386 | Tomm40l | Rat | valproic acid | increases expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TOMM40L mRNA | CTD | PMID:23179753 and PMID:26272509 | Tomm40l | Rat | valproic acid | affects expression | ISO | TOMM40L (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TOMM40L mRNA | CTD | PMID:25979313 | Tomm40l | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of TOMM40L mRNA | CTD | PMID:23034163 | |