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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1604296 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DSCC1 mRNA | CTD | PMID:22079256 | 1,1-dichloroethene | increases expression | ISO | RGD:1619130 | 6480464 | vinylidene chloride results in increased expression of DSCC1 mRNA | CTD | PMID:26682919 | 17beta-estradiol | increases expression | ISO | RGD:1604296 | 6480464 | Estradiol results in increased expression of DSCC1 mRNA | CTD | PMID:19167446 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:1619130 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:1619130 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1619130 | 6480464 | Tetrachlorodibenzodioxin affects the expression of DSCC1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DSCC1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1604296 | 6480464 | Tetrachlorodibenzodioxin affects the expression of DSCC1 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1604296 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DSCC1 mRNA | CTD | PMID:20106945, PMID:21632981 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of DSCC1 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of DSCC1 mRNA | CTD | PMID:31881176 | aflatoxin B1 | affects expression | ISO | RGD:1604296 | 6480464 | Aflatoxin B1 affects the expression of DSCC1 protein | CTD | PMID:20106945 | aflatoxin B1 | increases methylation | ISO | RGD:1604296 | 6480464 | Aflatoxin B1 results in increased methylation of DSCC1 gene | CTD | PMID:27153756 | aflatoxin B1 | increases expression | ISO | RGD:1604296 | 6480464 | Aflatoxin B1 results in increased expression of DSCC1 mRNA | CTD | PMID:22100608 | all-trans-retinoic acid | decreases expression | ISO | RGD:1604296 | 6480464 | Tretinoin results in decreased expression of DSCC1 mRNA | CTD | PMID:33167477 | antirheumatic drug | increases expression | ISO | RGD:1604296 | 6480464 | Antirheumatic Agents results in increased expression of DSCC1 mRNA | CTD | PMID:24449571 | atorvastatin calcium | affects response to substance | ISO | RGD:1604296 | 6480464 | DSCC1 protein affects the susceptibility to Atorvastatin | CTD | PMID:35926565 | atrazine | decreases expression | ISO | RGD:1604296 | 6480464 | Atrazine results in decreased expression of DSCC1 mRNA | CTD | PMID:22378314 | azathioprine | decreases expression | ISO | RGD:1604296 | 6480464 | Azathioprine results in decreased expression of DSCC1 mRNA | CTD | PMID:22623647 | benzo[a]pyrene | affects methylation | ISO | RGD:1604296 | 6480464 | Benzo(a)pyrene affects the methylation of DSCC1 intron, Benzo(a)pyrene affects the methylation of DSCC1 promoter | CTD | PMID:27901495, PMID:30157460 | benzo[a]pyrene | increases expression | ISO | RGD:1604296 | 6480464 | Benzo(a)pyrene results in increased expression of DSCC1 mRNA | CTD | PMID:32234424 | bis(2-chloroethyl) sulfide | decreases expression | ISO | RGD:1604296 | 6480464 | Mustard Gas results in decreased expression of DSCC1 mRNA | CTD | PMID:25102026 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DSCC1 mRNA | CTD | PMID:25181051 more ... | bisphenol A | decreases expression | ISO | RGD:1604296 | 6480464 | bisphenol A results in decreased expression of DSCC1 mRNA | CTD | PMID:29275510 | calcitriol | decreases expression | ISO | RGD:1604296 | 6480464 | Calcitriol results in decreased expression of DSCC1 mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | RGD:1604296 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of DSCC1 mRNA | CTD | PMID:21592394 | cannabidiol | decreases expression | ISO | RGD:1604296 | 6480464 | Cannabidiol results in decreased expression of DSCC1 mRNA | CTD | PMID:33244087 | carbon nanotube | increases expression | ISO | RGD:1619130 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of DSCC1 mRNA | CTD | PMID:18500788 | CGP 52608 | multiple interactions | ISO | RGD:1604296 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DSCC1 gene] | CTD | PMID:28238834 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of DSCC1 mRNA | CTD | PMID:22023808 | cisplatin | increases expression | ISO | RGD:1604296 | 6480464 | Cisplatin results in increased expression of DSCC1 mRNA | CTD | PMID:27594783 | copper atom | multiple interactions | ISO | RGD:1604296 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of DSCC1 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | RGD:1604296 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of DSCC1 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | RGD:1604296 | 6480464 | Copper Sulfate results in decreased expression of DSCC1 mRNA | CTD | PMID:19549813 | coumarin | increases expression | EXP | | 6480464 | coumarin results in increased expression of DSCC1 mRNA | CTD | PMID:18480146 | coumestrol | multiple interactions | ISO | RGD:1604296 | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | coumestrol | increases expression | ISO | RGD:1604296 | 6480464 | Coumestrol results in increased expression of DSCC1 mRNA | CTD | PMID:19167446 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of DSCC1 mRNA | CTD | PMID:26577399 | cyclosporin A | decreases expression | ISO | RGD:1604296 | 6480464 | Cyclosporine results in decreased expression of DSCC1 mRNA | CTD | PMID:20106945 more ... | dibutyl phthalate | decreases expression | ISO | RGD:1619130 | 6480464 | Dibutyl Phthalate results in decreased expression of DSCC1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of DSCC1 mRNA | CTD | PMID:21266533 | dioxygen | decreases expression | ISO | RGD:1604296 | 6480464 | Oxygen deficiency results in decreased expression of DSCC1 mRNA | CTD | PMID:26516004 | doxorubicin | affects response to substance | ISO | RGD:1604296 | 6480464 | DSCC1 protein affects the susceptibility to Doxorubicin | CTD | PMID:16217747 | Enterolactone | multiple interactions | ISO | RGD:1604296 | 6480464 | [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DSCC1 mRNA | CTD | PMID:19167446 | epoxiconazole | increases expression | ISO | RGD:1619130 | 6480464 | epoxiconazole results in increased expression of DSCC1 mRNA | CTD | PMID:35436446 | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of DSCC1 mRNA | CTD | PMID:34044035 | hydralazine | multiple interactions | ISO | RGD:1604296 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of DSCC1 mRNA | CTD | PMID:17183730 | Lasiocarpine | increases expression | ISO | RGD:1604296 | 6480464 | lasiocarpine results in increased expression of DSCC1 mRNA | CTD | PMID:32234424 | lidocaine | increases expression | EXP | | 6480464 | Lidocaine results in increased expression of DSCC1 mRNA | CTD | PMID:35283115 | lipopolysaccharide | multiple interactions | ISO | RGD:1604296 | 6480464 | [S-(1, 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of DSCC1 mRNA | CTD | PMID:35811015 | methyl methanesulfonate | increases expression | ISO | RGD:1604296 | 6480464 | Methyl Methanesulfonate results in increased expression of DSCC1 mRNA | CTD | PMID:23649840 | N-methyl-4-phenylpyridinium | decreases expression | ISO | RGD:1604296 | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of DSCC1 mRNA | CTD | PMID:24810058 | niclosamide | multiple interactions | ISO | RGD:1604296 | 6480464 | Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA] | CTD | PMID:27542212 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DSCC1 mRNA | CTD | PMID:25729387 | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of DSCC1 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | RGD:1619130 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of DSCC1 mRNA more ... | CTD | PMID:25658374, PMID:34911549 | paracetamol | increases expression | ISO | RGD:1604296 | 6480464 | Acetaminophen results in increased expression of DSCC1 mRNA | CTD | PMID:22230336 | PCB138 | multiple interactions | ISO | RGD:1619130 | 6480464 | [2 more ... | CTD | PMID:25510870 | pirinixic acid | multiple interactions | ISO | RGD:1619130 | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of DSCC1 mRNA | CTD | PMID:20813756 | pirinixic acid | increases expression | ISO | RGD:1619130 | 6480464 | pirinixic acid results in increased expression of DSCC1 mRNA | CTD | PMID:20813756 | potassium chromate | multiple interactions | ISO | RGD:1604296 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DSCC1 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | RGD:1604296 | 6480464 | potassium chromate(VI) results in decreased expression of DSCC1 mRNA | CTD | PMID:22079256 | propanal | decreases expression | ISO | RGD:1604296 | 6480464 | propionaldehyde results in decreased expression of DSCC1 mRNA | CTD | PMID:26079696 | pyrvinium | multiple interactions | ISO | RGD:1604296 | 6480464 | pyrvinium inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA] | CTD | PMID:27542212 | quercetin | affects expression | ISO | RGD:1604296 | 6480464 | Quercetin affects the expression of DSCC1 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | RGD:1604296 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of DSCC1 mRNA | CTD | PMID:19167446 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | RGD:1604296 | 6480464 | [S-(1, 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of DSCC1 mRNA | CTD | PMID:35811015 | silicon dioxide | increases expression | ISO | RGD:1604296 | 6480464 | Silicon Dioxide analog results in increased expression of DSCC1 mRNA | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | RGD:1604296 | 6480464 | sodium arsenite results in increased expression of DSCC1 mRNA | CTD | PMID:29301061, PMID:34032870 | succimer | multiple interactions | ISO | RGD:1619130 | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of DSCC1 mRNA | CTD | PMID:21641980 | sunitinib | decreases expression | ISO | RGD:1604296 | 6480464 | Sunitinib results in decreased expression of DSCC1 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | RGD:1604296 | 6480464 | Temozolomide results in increased expression of DSCC1 mRNA | CTD | PMID:31758290 | testosterone | multiple interactions | ISO | RGD:1604296 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of DSCC1 mRNA | CTD | PMID:21592394 | testosterone | decreases expression | ISO | RGD:1604296 | 6480464 | Testosterone results in decreased expression of DSCC1 mRNA | CTD | PMID:21592394, PMID:33359661 | tetrachloromethane | affects expression | ISO | RGD:1619130 | 6480464 | Carbon Tetrachloride affects the expression of DSCC1 mRNA | CTD | PMID:17484886 | tetrachloromethane | increases expression | ISO | RGD:1619130 | 6480464 | Carbon Tetrachloride results in increased expression of DSCC1 mRNA | CTD | PMID:31919559 | thapsigargin | decreases expression | ISO | RGD:1604296 | 6480464 | Thapsigargin results in decreased expression of DSCC1 mRNA | CTD | PMID:22378314 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of DSCC1 mRNA | CTD | PMID:23411599 | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of DSCC1 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | RGD:1619130 | 6480464 | titanium dioxide results in increased expression of DSCC1 mRNA | CTD | PMID:23557971 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of DSCC1 mRNA | CTD | PMID:30012374 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DSCC1 mRNA | CTD | PMID:25729387 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of DSCC1 mRNA | CTD | PMID:25729387 | trimellitic anhydride | increases expression | ISO | RGD:1619130 | 6480464 | trimellitic anhydride results in increased expression of DSCC1 mRNA | CTD | PMID:19042947 | triptonide | decreases expression | ISO | RGD:1619130 | 6480464 | triptonide results in decreased expression of DSCC1 mRNA | CTD | PMID:33045310 | trovafloxacin | decreases expression | ISO | RGD:1619130 | 6480464 | trovafloxacin results in decreased expression of DSCC1 mRNA | CTD | PMID:35537566 | tungsten | increases expression | ISO | RGD:1619130 | 6480464 | Tungsten results in increased expression of DSCC1 mRNA | CTD | PMID:30912803 | valproic acid | affects expression | ISO | RGD:1604296 | 6480464 | Valproic Acid affects the expression of DSCC1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | RGD:1604296 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of DSCC1 mRNA | CTD | PMID:17183730 | vincaleukoblastine | affects response to substance | ISO | RGD:1604296 | 6480464 | DSCC1 protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 | |