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Gene: Jam2 (junctional adhesion molecule 2) Rattus norvegicus

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Symbol:

Jam2

Name:

junctional adhesion molecule 2

RGD ID:

1561692

Description:

Predicted to enable integrin binding activity. Predicted to be involved in several processes, including hematopoietic stem cell migration to bone marrow; leukocyte tethering or rolling; and negative regulation of myelination. Predicted to act upstream of or within negative regulation of cell adhesion. Predicted to be located in cell-cell contact zone and somatodendritic compartment. Predicted to be part of protein complex involved in cell adhesion. Predicted to be active in cell surface; plasma membrane; and tight junction. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human JAM2 (junctional adhesion molecule 2); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

junction adhesion molecule 2; junctional adhesion molecule B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	JAM2 (junctional adhesion molecule 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Jam2 (junction adhesion molecule 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Jam2 (junctional adhesion molecule 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	JAM2 (junctional adhesion molecule 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	JAM2 (junctional adhesion molecule 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Jam2 (junctional adhesion molecule 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	JAM2 (junctional adhesion molecule 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	JAM2 (junctional adhesion molecule 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Jam2 (junctional adhesion molecule 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	JAM2 (junctional adhesion molecule 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Jam2 (junction adhesion molecule 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	jam2b (junctional adhesion molecule 2b)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	jam2a (junctional adhesion molecule 2a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	jam2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	37,316,287 - 37,366,517 (+)	NCBI		GRCr8
mRatBN7.2	11	23,830,820 - 23,880,071 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	23,831,106 - 23,880,063 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	32,537,340 - 32,586,308 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	25,237,747 - 25,286,715 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	24,426,449 - 24,475,421 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	24,235,310 - 24,285,279 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	24,266,345 - 24,285,275 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	27,864,652 - 27,913,275 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	24,310,704 - 24,315,219 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	11	23,670,522 - 23,719,259 (+)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

JBrowse:

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Model

Annotation Click to see Annotation Detail View

RGD Manual Disease Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Jam2	Rat	allergic contact dermatitis		ISO	RGD:1615884	7488919		RGD

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Jam2	Rat	Alzheimer's disease		ISO	RGD:1343747	8554872	ClinVar Annotator: match by term: Alzheimer disease	ClinVar	PMID:16369530\|PMID:16921174\|PMID:24691562\|PMID:25741868
Jam2	Rat	Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy		ISO	RGD:1343747	8554872	ClinVar Annotator: match by term: Alzheimer disease, early-onset, with cerebral amyloid angiopathy	ClinVar	PMID:16369530\|PMID:19047566
Jam2	Rat	genetic disease		ISO	RGD:1343747	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar
Jam2	Rat	Idiopathic Basal Ganglia Calcification 8		ISO	RGD:1343747	8554872	ClinVar Annotator: match by term: Basal ganglia calcification, idiopathic, 8, autosomal recessive \| ClinVar Annotator: more ...	ClinVar	PMID:25741868\|PMID:26136916\|PMID:31851307\|PMID:32142645
Jam2	Rat	Neurodevelopmental Disorders		ISO	RGD:1343747	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868

Imported Disease Annotations - CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Jam2	Rat	autism spectrum disorder		ISO	RGD:1343747	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:35663546

Imported Disease Annotations - OMIM

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Jam2	Rat	Idiopathic Basal Ganglia Calcification 8		ISO	RGD:1343747	7240710		OMIM

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Jam2	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	RGD:1615884	6480464	Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of JAM2 mRNA]	CTD	PMID:22206623
Jam2	Rat	1,2-dimethylhydrazine	increases expression	ISO	RGD:1615884	6480464	1,2-Dimethylhydrazine results in increased expression of JAM2 mRNA	CTD	PMID:22206623
Jam2	Rat	1,3-dinitrobenzene	increases expression	EXP		6480464	3-dinitrobenzene results in increased expression of JAM2 mRNA	CTD	PMID:24140754
Jam2	Rat	17alpha-ethynylestradiol	affects expression	ISO	RGD:1615884	6480464	Ethinyl Estradiol affects the expression of JAM2 mRNA	CTD	PMID:17555576
Jam2	Rat	17alpha-ethynylestradiol	multiple interactions	ISO	RGD:1615884	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of JAM2 mRNA	CTD	PMID:17942748
Jam2	Rat	17alpha-ethynylestradiol	increases expression	ISO	RGD:1615884	6480464	Ethinyl Estradiol results in increased expression of JAM2 mRNA	CTD	PMID:17942748
Jam2	Rat	17beta-estradiol	affects expression	ISO	RGD:1343747	6480464	Estradiol affects the expression of JAM2 mRNA	CTD	PMID:25321415
Jam2	Rat	17beta-estradiol	decreases expression	ISO	RGD:1615884	6480464	Estradiol results in decreased expression of JAM2 mRNA	CTD	PMID:39298647
Jam2	Rat	17beta-estradiol	multiple interactions	ISO	RGD:1343747	6480464	[Estradiol co-treated with TGFB1 protein] results in increased expression of JAM2 mRNA	CTD	PMID:30165855
Jam2	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	RGD:1615884	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of JAM2 mRNA; [TIPARP gene mutant more ...	CTD	PMID:17942748\|PMID:19654925\|PMID:25975270
Jam2	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of JAM2 mRNA	CTD	PMID:34747641
Jam2	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1615884	6480464	Tetrachlorodibenzodioxin affects the expression of JAM2 mRNA	CTD	PMID:26377647
Jam2	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:1615884	6480464	Tetrachlorodibenzodioxin results in increased expression of JAM2 mRNA	CTD	PMID:19465110\|PMID:19770486
Jam2	Rat	2,4-dibromophenyl 2,4,5-tribromophenyl ether	decreases expression	ISO	RGD:1343747	6480464	2,2',4,4',5-brominated diphenyl ether results in decreased expression of JAM2 mRNA	CTD	PMID:26705709
Jam2	Rat	2,4-dibromophenyl 2,4,5-tribromophenyl ether	affects expression	ISO	RGD:1615884	6480464	2,2',4,4',5-brominated diphenyl ether affects the expression of JAM2 mRNA	CTD	PMID:38648751
Jam2	Rat	3,7-dihydropurine-6-thione	increases expression	EXP		6480464	Mercaptopurine results in increased expression of JAM2 mRNA	CTD	PMID:23358152
Jam2	Rat	3-isobutyl-1-methyl-7H-xanthine	multiple interactions	ISO	RGD:1615884	6480464	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of JAM2 mRNA	CTD	PMID:24848799
Jam2	Rat	3-Nitrobenzanthrone	affects expression	ISO	RGD:1343747	6480464	3-nitrobenzanthrone affects the expression of JAM2 mRNA	CTD	PMID:34036453
Jam2	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	RGD:1343747	6480464	bisphenol S results in decreased expression of JAM2 mRNA	CTD	PMID:27685785
Jam2	Rat	4-hydroxyphenyl retinamide	decreases expression	ISO	RGD:1615884	6480464	Fenretinide results in decreased expression of JAM2 mRNA	CTD	PMID:28973697
Jam2	Rat	acetamide	increases expression	EXP		6480464	acetamide results in increased expression of JAM2 mRNA	CTD	PMID:31881176
Jam2	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of JAM2 mRNA	CTD	PMID:28959563
Jam2	Rat	acrylamide	decreases expression	ISO	RGD:1343747	6480464	Acrylamide results in decreased expression of JAM2 mRNA	CTD	PMID:32763439
Jam2	Rat	aflatoxin B1	decreases methylation	ISO	RGD:1343747	6480464	Aflatoxin B1 results in decreased methylation of JAM2 gene	CTD	PMID:27153756
Jam2	Rat	all-trans-retinoic acid	multiple interactions	ISO	RGD:1615884	6480464	[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of JAM2 mRNA	CTD	PMID:36189433
Jam2	Rat	amphetamine	increases expression	EXP		6480464	Amphetamine results in increased expression of JAM2 mRNA	CTD	PMID:30779732
Jam2	Rat	antirheumatic drug	increases expression	ISO	RGD:1343747	6480464	Antirheumatic Agents results in increased expression of JAM2 mRNA	CTD	PMID:24449571
Jam2	Rat	arsane	affects methylation	ISO	RGD:1343747	6480464	Arsenic affects the methylation of JAM2 gene	CTD	PMID:25304211
Jam2	Rat	arsenic atom	affects methylation	ISO	RGD:1343747	6480464	Arsenic affects the methylation of JAM2 gene	CTD	PMID:25304211
Jam2	Rat	arsenite(3-)	increases expression	ISO	RGD:1615884	6480464	arsenite results in increased expression of JAM2 mRNA	CTD	PMID:18191166
Jam2	Rat	arsenite(3-)	increases methylation	ISO	RGD:1343747	6480464	arsenite results in increased methylation of JAM2 promoter	CTD	PMID:23974009
Jam2	Rat	arsenous acid	increases expression	ISO	RGD:1343747	6480464	Arsenic Trioxide results in increased expression of JAM2 mRNA	CTD	PMID:27829220
Jam2	Rat	atrazine	increases expression	ISO	RGD:1343747	6480464	Atrazine results in increased expression of JAM2 mRNA	CTD	PMID:22378314
Jam2	Rat	atrazine	increases expression	EXP		6480464	Atrazine results in increased expression of JAM2 mRNA	CTD	PMID:36841081
Jam2	Rat	Azoxymethane	multiple interactions	ISO	RGD:1615884	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of JAM2 more ...	CTD	PMID:29950665
Jam2	Rat	benzo[a]pyrene	decreases expression	ISO	RGD:1615884	6480464	Benzo(a)pyrene results in decreased expression of JAM2 mRNA	CTD	PMID:19770486
Jam2	Rat	benzo[a]pyrene	increases methylation	ISO	RGD:1343747	6480464	Benzo(a)pyrene results in increased methylation of JAM2 exon	CTD	PMID:27901495
Jam2	Rat	benzo[a]pyrene	decreases methylation	ISO	RGD:1343747	6480464	Benzo(a)pyrene results in decreased methylation of JAM2 3' UTR; Benzo(a)pyrene results in decreased methylation of more ...	CTD	PMID:27901495
Jam2	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1615884	6480464	Benzo(a)pyrene results in increased expression of JAM2 mRNA	CTD	PMID:22228805\|PMID:32417428
Jam2	Rat	beta-naphthoflavone	multiple interactions	EXP		6480464	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of JAM2 mRNA	CTD	PMID:18164116
Jam2	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of JAM2 mRNA	CTD	PMID:25181051
Jam2	Rat	bisphenol A	increases expression	ISO	RGD:1615884	6480464	bisphenol A results in increased expression of JAM2 mRNA	CTD	PMID:30951980
Jam2	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of JAM2 mRNA	CTD	PMID:30816183\|PMID:32528016
Jam2	Rat	bisphenol F	increases expression	ISO	RGD:1615884	6480464	bisphenol F results in increased expression of JAM2 mRNA	CTD	PMID:30951980
Jam2	Rat	buspirone	decreases expression	EXP		6480464	Buspirone results in decreased expression of JAM2 mRNA	CTD	PMID:24136188
Jam2	Rat	cannabidiol	decreases expression	ISO	RGD:1343747	6480464	Cannabidiol results in decreased expression of JAM2 mRNA	CTD	PMID:27918106
Jam2	Rat	cantharidin	decreases expression	ISO	RGD:1615884	6480464	Cantharidin results in decreased expression of JAM2 mRNA	CTD	PMID:36907384
Jam2	Rat	carbon nanotube	increases expression	ISO	RGD:1615884	6480464	Nanotubes, Carbon analog results in increased expression of JAM2 mRNA	CTD	PMID:25554681
Jam2	Rat	CGP 52608	multiple interactions	ISO	RGD:1343747	6480464	CGP 52608 promotes the reaction [RORA protein binds to JAM2 gene]	CTD	PMID:28238834
Jam2	Rat	chloroprene	increases expression	EXP		6480464	Chloroprene results in increased expression of JAM2 mRNA	CTD	PMID:23125180
Jam2	Rat	cytarabine	increases expression	ISO	RGD:1343747	6480464	Cytarabine results in increased expression of JAM2 mRNA	CTD	PMID:21198554
Jam2	Rat	dexamethasone	decreases expression	ISO	RGD:1343747	6480464	Dexamethasone results in decreased expression of JAM2 mRNA	CTD	PMID:25047013
Jam2	Rat	dexamethasone	multiple interactions	ISO	RGD:1615884	6480464	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of JAM2 mRNA	CTD	PMID:24848799
Jam2	Rat	dextran sulfate	multiple interactions	ISO	RGD:1615884	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of JAM2 more ...	CTD	PMID:29950665
Jam2	Rat	diarsenic trioxide	increases expression	ISO	RGD:1343747	6480464	Arsenic Trioxide results in increased expression of JAM2 mRNA	CTD	PMID:27829220
Jam2	Rat	dibenz[a,h]anthracene	increases expression	ISO	RGD:1615884	6480464	1,2,5,6-dibenzanthracene results in increased expression of JAM2 mRNA	CTD	PMID:26377693
Jam2	Rat	dibenzofurans	increases expression	ISO	RGD:1615884	6480464	Dibenzofurans results in increased expression of JAM2 mRNA	CTD	PMID:34254344
Jam2	Rat	dibutyl phthalate	decreases expression	ISO	RGD:1615884	6480464	Dibutyl Phthalate results in decreased expression of JAM2 mRNA	CTD	PMID:21266533
Jam2	Rat	dioxygen	increases expression	ISO	RGD:1343747	6480464	Oxygen deficiency results in increased expression of JAM2 mRNA	CTD	PMID:26516004
Jam2	Rat	diuron	increases expression	EXP		6480464	Diuron results in increased expression of JAM2 mRNA	CTD	PMID:21551480
Jam2	Rat	dorsomorphin	multiple interactions	ISO	RGD:1343747	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Jam2	Rat	doxorubicin	decreases expression	ISO	RGD:1343747	6480464	Doxorubicin results in decreased expression of JAM2 mRNA	CTD	PMID:29803840
Jam2	Rat	ethanol	increases expression	ISO	RGD:1615884	6480464	Ethanol results in increased expression of JAM2 mRNA	CTD	PMID:30319688
Jam2	Rat	ethylparaben	decreases expression	ISO	RGD:1343747	6480464	ethyl-p-hydroxybenzoate results in decreased expression of JAM2 mRNA	CTD	PMID:37690743
Jam2	Rat	folic acid	multiple interactions	ISO	RGD:1615884	6480464	Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of JAM2 mRNA]	CTD	PMID:22206623
Jam2	Rat	fonofos	increases methylation	ISO	RGD:1343747	6480464	Fonofos results in increased methylation of JAM2 promoter	CTD	PMID:22847954
Jam2	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of JAM2 mRNA	CTD	PMID:22061828
Jam2	Rat	glafenine	increases expression	EXP		6480464	Glafenine results in increased expression of JAM2 mRNA	CTD	PMID:24136188
Jam2	Rat	mercaptopurine	increases expression	EXP		6480464	Mercaptopurine results in increased expression of JAM2 mRNA	CTD	PMID:23358152
Jam2	Rat	mercury dibromide	decreases expression	ISO	RGD:1343747	6480464	mercuric bromide results in decreased expression of JAM2 mRNA	CTD	PMID:26272509
Jam2	Rat	mercury dibromide	multiple interactions	ISO	RGD:1343747	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Jam2	Rat	methylmercury chloride	decreases expression	ISO	RGD:1343747	6480464	methylmercuric chloride results in decreased expression of JAM2 mRNA	CTD	PMID:28001369
Jam2	Rat	mono(2-ethylhexyl) phthalate	multiple interactions	ISO	RGD:1615884	6480464	[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of JAM2 mRNA	CTD	PMID:36189433
Jam2	Rat	N-methyl-N-nitrosourea	decreases expression	ISO	RGD:1615884	6480464	Methylnitrosourea results in decreased expression of JAM2 mRNA	CTD	PMID:25270620
Jam2	Rat	N-nitrosodiethylamine	multiple interactions	EXP		6480464	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of JAM2 mRNA	CTD	PMID:18164116
Jam2	Rat	naphthalene	decreases expression	EXP		6480464	naphthalene analog results in decreased expression of JAM2 mRNA	CTD	PMID:24976557
Jam2	Rat	nickel atom	decreases expression	ISO	RGD:1343747	6480464	Nickel results in decreased expression of JAM2 mRNA	CTD	PMID:25583101
Jam2	Rat	okadaic acid	decreases expression	ISO	RGD:1343747	6480464	Okadaic Acid results in decreased expression of JAM2 mRNA	CTD	PMID:38832940
Jam2	Rat	ozone	multiple interactions	ISO	RGD:1615884	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ...	CTD	PMID:34911549
Jam2	Rat	paracetamol	affects expression	ISO	RGD:1615884	6480464	Acetaminophen affects the expression of JAM2 mRNA	CTD	PMID:17562736
Jam2	Rat	parathion	increases methylation	ISO	RGD:1343747	6480464	Parathion results in increased methylation of JAM2 promoter	CTD	PMID:22847954
Jam2	Rat	perfluorohexanesulfonic acid	increases expression	ISO	RGD:1615884	6480464	perfluorohexanesulfonic acid results in increased expression of JAM2 mRNA	CTD	PMID:37995155
Jam2	Rat	permethrin	increases expression	ISO	RGD:1343747	6480464	Permethrin results in increased expression of JAM2 mRNA	CTD	PMID:37047231
Jam2	Rat	phenobarbital	affects expression	ISO	RGD:1615884	6480464	Phenobarbital affects the expression of JAM2 mRNA	CTD	PMID:23091169
Jam2	Rat	phenylmercury acetate	decreases expression	ISO	RGD:1343747	6480464	Phenylmercuric Acetate results in decreased expression of JAM2 mRNA	CTD	PMID:26272509
Jam2	Rat	phenylmercury acetate	multiple interactions	ISO	RGD:1343747	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Jam2	Rat	pirinixic acid	decreases expression	ISO	RGD:1615884	6480464	pirinixic acid results in decreased expression of JAM2 mRNA	CTD	PMID:25270620
Jam2	Rat	pregnenolone 16alpha-carbonitrile	increases expression	ISO	RGD:1615884	6480464	Pregnenolone Carbonitrile results in increased expression of JAM2 mRNA	CTD	PMID:28903501
Jam2	Rat	progesterone	increases expression	ISO	RGD:1615884	6480464	Progesterone results in increased expression of JAM2 mRNA	CTD	PMID:22238285
Jam2	Rat	purine-6-thiol	increases expression	EXP		6480464	Mercaptopurine results in increased expression of JAM2 mRNA	CTD	PMID:23358152
Jam2	Rat	SB 431542	multiple interactions	ISO	RGD:1343747	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Jam2	Rat	silicon dioxide	increases expression	ISO	RGD:1343747	6480464	Silicon Dioxide analog results in increased expression of JAM2 mRNA	CTD	PMID:23806026
Jam2	Rat	silicon dioxide	increases expression	ISO	RGD:1615884	6480464	Silicon Dioxide results in increased expression of JAM2 mRNA	CTD	PMID:23221170
Jam2	Rat	silver atom	decreases expression	ISO	RGD:1615884	6480464	Silver results in decreased expression of JAM2 mRNA	CTD	PMID:27131904
Jam2	Rat	silver(0)	decreases expression	ISO	RGD:1615884	6480464	Silver results in decreased expression of JAM2 mRNA	CTD	PMID:27131904
Jam2	Rat	sodium arsenate	increases expression	ISO	RGD:1615884	6480464	sodium arsenate results in increased expression of JAM2 mRNA	CTD	PMID:21795629
Jam2	Rat	sodium arsenite	increases expression	ISO	RGD:1343747	6480464	sodium arsenite results in increased expression of JAM2 mRNA	CTD	PMID:22714537
Jam2	Rat	sodium arsenite	decreases expression	ISO	RGD:1615884	6480464	sodium arsenite results in decreased expression of JAM2 mRNA	CTD	PMID:37682722
Jam2	Rat	sodium dichromate	increases expression	EXP		6480464	sodium bichromate results in increased expression of JAM2 mRNA	CTD	PMID:25993096
Jam2	Rat	Soman	increases expression	EXP		6480464	Soman results in increased expression of JAM2 mRNA	CTD	PMID:19281266
Jam2	Rat	sotorasib	multiple interactions	ISO	RGD:1343747	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of JAM2 mRNA	CTD	PMID:36139627
Jam2	Rat	tamoxifen	affects expression	ISO	RGD:1615884	6480464	Tamoxifen affects the expression of JAM2 mRNA	CTD	PMID:17555576
Jam2	Rat	terbufos	increases methylation	ISO	RGD:1343747	6480464	terbufos results in increased methylation of JAM2 promoter	CTD	PMID:22847954
Jam2	Rat	tetrachloromethane	increases expression	ISO	RGD:1615884	6480464	Carbon Tetrachloride results in increased expression of JAM2 mRNA	CTD	PMID:31919559
Jam2	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of JAM2 mRNA	CTD	PMID:34492290
Jam2	Rat	titanium dioxide	multiple interactions	ISO	RGD:1615884	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of JAM2 more ...	CTD	PMID:29950665
Jam2	Rat	titanium dioxide	increases methylation	ISO	RGD:1615884	6480464	titanium dioxide results in increased methylation of JAM2 gene	CTD	PMID:35295148
Jam2	Rat	titanium dioxide	decreases methylation	ISO	RGD:1615884	6480464	titanium dioxide results in decreased methylation of JAM2 gene	CTD	PMID:35295148
Jam2	Rat	trametinib	multiple interactions	ISO	RGD:1343747	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of JAM2 mRNA	CTD	PMID:36139627
Jam2	Rat	tributylstannane	increases expression	ISO	RGD:1615884	6480464	tributyltin results in increased expression of JAM2 mRNA	CTD	PMID:24848799
Jam2	Rat	valproic acid	decreases expression	ISO	RGD:1343747	6480464	Valproic Acid results in decreased expression of JAM2 mRNA	CTD	PMID:23179753\|PMID:28001369
Jam2	Rat	vanadyl sulfate	increases expression	ISO	RGD:1343747	6480464	vanadyl sulfate results in increased expression of JAM2 mRNA	CTD	PMID:16330358

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Jam2	Rat	cell-cell adhesion	involved_in	ISO	RGD:1343747	1624291	PMID:24357068	RGD	PMID:24357068
Jam2	Rat	cell-cell adhesion	involved_in	ISO	RGD:1615884	1624291	PMID:24357068	RGD	PMID:24357068
Jam2	Rat	cell-cell adhesion	involved_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	cellular extravasation	involved_in	ISO	RGD:1615884	1624291	PMID:12239159	RGD	PMID:12239159
Jam2	Rat	cellular extravasation	involved_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	cellular extravasation	involved_in	ISO	RGD:1343747	1624291	PMID:12239159	RGD	PMID:12239159
Jam2	Rat	hematopoietic stem cell migration to bone marrow	involved_in	ISO	RGD:1615884	1624291	PMID:24357068	RGD	PMID:24357068
Jam2	Rat	hematopoietic stem cell migration to bone marrow	involved_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	hematopoietic stem cell migration to bone marrow	involved_in	ISO	RGD:1343747	1624291	PMID:24357068	RGD	PMID:24357068
Jam2	Rat	leukocyte cell-cell adhesion	involved_in	IBA	MGI:1933820\|PANTHER:PTN002893769\|UniProtKB:P57087	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Jam2	Rat	leukocyte tethering or rolling	involved_in	ISO	RGD:1343747	1624291	PMID:19740376	RGD	PMID:19740376
Jam2	Rat	leukocyte tethering or rolling	involved_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	leukocyte tethering or rolling	involved_in	ISO	RGD:1615884	1624291	PMID:19740376	RGD	PMID:19740376
Jam2	Rat	lymphocyte aggregation	involved_in	ISO	RGD:1343747	1624291	PMID:11823489	RGD	PMID:11823489
Jam2	Rat	lymphocyte aggregation	involved_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	negative regulation of cell adhesion	acts_upstream_of_or_within	ISO	RGD:1615884	1624291	MGI:1933825\|MGI:96607\|MGI:96611 PMID:16093349	RGD	PMID:16093349
Jam2	Rat	negative regulation of myelination	involved_in	ISO	RGD:1615884	1624291	PMID:27499083	RGD	PMID:27499083
Jam2	Rat	positive regulation of lymphocyte migration	involved_in	ISO	RGD:1343747	1624291	PMID:12239159	RGD	PMID:12239159
Jam2	Rat	positive regulation of lymphocyte migration	involved_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	positive regulation of lymphocyte migration	involved_in	ISO	RGD:1615884	1624291	PMID:12239159	RGD	PMID:12239159
Jam2	Rat	spermatid development	involved_in	ISO	RGD:1615884	1624291	PMID:15372036	RGD	PMID:15372036

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Jam2	Rat	axon	NOT\|located_in	ISO	RGD:1615884	1624291	PMID:27499083	RGD	PMID:27499083
Jam2	Rat	cell surface	located_in	ISO	RGD:1343747	1624291	PMID:19740376	RGD	PMID:19740376
Jam2	Rat	cell surface	located_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	cell surface	is_active_in	IBA	MGI:1933820\|PANTHER:PTN002893769\|UniProtKB:P57087	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Jam2	Rat	cell surface	located_in	ISO	RGD:1615884	1624291	PMID:12239159	RGD	PMID:12239159
Jam2	Rat	cell-cell contact zone	located_in	ISO	RGD:1343747	1624291	PMID:12239159	RGD	PMID:12239159
Jam2	Rat	cell-cell contact zone	located_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Jam2	Rat	plasma membrane	located_in	ISO	RGD:1343747	1624291	PMID:11590146, PMID:31851307	RGD	PMID:11590146\|PMID:31851307
Jam2	Rat	plasma membrane	located_in	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	plasma membrane	is_active_in	IBA	PANTHER:PTN002893769\|UniProtKB:P57087	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Jam2	Rat	protein complex involved in cell adhesion	part_of	ISO	RGD:1343747	1624291	PMID:11590146	RGD	PMID:11590146
Jam2	Rat	protein complex involved in cell adhesion	part_of	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	protein complex involved in cell adhesion	part_of	IBA	PANTHER:PTN002893769\|UniProtKB:P57087	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Jam2	Rat	somatodendritic compartment	located_in	ISO	RGD:1615884	1624291	PMID:27499083	RGD	PMID:27499083
Jam2	Rat	tight junction	located_in	ISO	RGD:1615884	1624291	PMID:15372036	RGD	PMID:15372036
Jam2	Rat	tight junction	is_active_in	IBA	MGI:1933820\|PANTHER:PTN002893769	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Jam2	Rat	integrin binding	enables	ISO	RGD:1343747	1624291	PMID:12070135	RGD	PMID:12070135
Jam2	Rat	integrin binding	enables	IEA	UniProtKB:P57087\|ensembl:ENSP00000420419	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Jam2	Rat	protein binding	enables	ISO	RGD:1343747	1624291	UniProtKB:Q9BX67 PMID:11590146, PMID:11823489, PMID:21982860	RGD	PMID:11590146\|PMID:11823489\|PMID:21982860
Jam2	Rat	protein binding	enables	ISO	RGD:1615884	1624291	PR:Q9D8B7 PMID:16093349	RGD	PMID:16093349

Disease Annotations Click to see Annotation Detail View

allergic contact dermatitis (ISO)

Alzheimer's disease (ISO)

Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy (ISO)

autism spectrum disorder (ISO)

genetic disease (ISO)

Idiopathic Basal Ganglia Calcification 8 (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3,7-dihydropurine-6-thione (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-Nitrobenzanthrone (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (EXP,ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (EXP)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buspirone (EXP)

cannabidiol (ISO)

cantharidin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (EXP)

cytarabine (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

dibenz[a,h]anthracene (ISO)

dibenzofurans (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

ethylparaben (ISO)

folic acid (ISO)

fonofos (ISO)

gentamycin (EXP)

glafenine (EXP)

mercaptopurine (EXP)

mercury dibromide (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-N-nitrosourea (ISO)

N-nitrosodiethylamine (EXP)

naphthalene (EXP)

nickel atom (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

parathion (ISO)

perfluorohexanesulfonic acid (ISO)

permethrin (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

progesterone (ISO)

purine-6-thiol (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (EXP)

sotorasib (ISO)

tamoxifen (ISO)

terbufos (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trametinib (ISO)

tributylstannane (ISO)

valproic acid (ISO)

vanadyl sulfate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell-cell adhesion (IEA,ISO)

cellular extravasation (IEA,ISO)

hematopoietic stem cell migration to bone marrow (IEA,ISO)

leukocyte cell-cell adhesion (IBA)

leukocyte tethering or rolling (IEA,ISO)

lymphocyte aggregation (IEA,ISO)

negative regulation of cell adhesion (ISO)

negative regulation of myelination (ISO)

positive regulation of lymphocyte migration (IEA,ISO)

spermatid development (ISO)

Cellular Component

axon (ISO)

cell surface (IBA,IEA,ISO)

cell-cell contact zone (IEA,ISO)

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

protein complex involved in cell adhesion (IBA,IEA,ISO)

somatodendritic compartment (ISO)

tight junction (IBA,ISO)

Molecular Function

integrin binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation.	Ludwig RJ, etal., J Invest Dermatol. 2005 Nov;125(5):969-76.
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11590146	PMID:11823489	PMID:12070135	PMID:12239159	PMID:15372036	PMID:16093349	PMID:19740376	PMID:24357068	PMID:27499083

Genomics

Comparative Map Data

Jam2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	37,316,287 - 37,366,517 (+)	NCBI		GRCr8
mRatBN7.2	11	23,830,820 - 23,880,071 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	23,831,106 - 23,880,063 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	32,537,340 - 32,586,308 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	25,237,747 - 25,286,715 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	24,426,449 - 24,475,421 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	24,235,310 - 24,285,279 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	24,266,345 - 24,285,275 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	27,864,652 - 27,913,275 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	24,310,704 - 24,315,219 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	11	23,670,522 - 23,719,259 (+)	NCBI		Celera
Cytogenetic Map	11	q11	NCBI

JAM2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	25,639,258 - 25,717,562 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	25,639,258 - 25,717,562 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	27,011,570 - 27,089,874 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	25,933,460 - 26,009,106 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	25,933,459 - 26,009,106	NCBI
Celera	21	12,195,003 - 12,270,650 (+)	NCBI		Celera
Cytogenetic Map	21	q21.3	NCBI
HuRef	21	12,414,742 - 12,493,008 (+)	NCBI		HuRef
CHM1_1	21	26,572,234 - 26,650,529 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	21	23,996,799 - 24,075,106 (+)	NCBI		T2T-CHM13v2.0

Jam2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	84,571,011 - 84,623,268 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	84,571,011 - 84,622,816 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	84,774,123 - 84,826,380 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	84,774,123 - 84,825,928 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	84,774,368 - 84,823,129 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	84,657,025 - 84,707,359 (+)	NCBI		MGSCv36	mm8
Celera	16	84,978,233 - 85,028,276 (+)	NCBI		Celera
Cytogenetic Map	16	C3.3	NCBI
cM Map	16	46.92	NCBI

Jam2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	25,571,570 - 25,599,551 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	25,531,891 - 25,599,551 (+)	NCBI	ChiLan1.0	ChiLan1.0

JAM2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	21,832,762 - 21,912,523 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	16,690,714 - 16,769,718 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	12,084,083 - 12,162,615 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	25,442,054 - 25,518,987 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	25,441,765 - 25,519,304 (+)	Ensembl	panpan1.1		panPan2

JAM2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	21,137,378 - 21,198,278 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	21,137,363 - 21,197,668 (+)	NCBI	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	21,194,569 - 21,197,958 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	21,191,218 - 21,252,072 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	21,191,320 - 21,253,587 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	21,209,766 - 21,270,172 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	21,210,940 - 21,271,401 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	21,686,386 - 21,746,819 (+)	NCBI		UU_Cfam_GSD_1.0

Jam2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	21,697,079 - 21,751,432 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936640	1,929,255 - 1,984,872 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936640	1,930,450 - 1,984,438 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JAM2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	189,165,975 - 189,275,839 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	189,199,789 - 189,275,843 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	199,074,626 - 199,167,813 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JAM2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	66,557,271 - 66,635,937 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	66,559,820 - 66,635,339 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	86,918,147 - 86,997,127 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Jam2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	13,704,652 - 13,776,172 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624745	13,704,031 - 13,778,749 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Jam2
91 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	356
Count of miRNA genes:	234
Interacting mature miRNAs:	268
Transcripts:	ENSRNOT00000046973
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
1598842	Glom10	Glomerulus QTL 10	3.4		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	1	35331169	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	19456205	76331918	Rat
724517	Uae18	Urinary albumin excretion QTL 18	3.7		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	16472047	44285911	Rat
2290451	Scl58	Serum cholesterol level QTL 58	3.48		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	11	12831046	25121472	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
1600394	Edcs1	Endometrial carcinoma susceptibility QTL1	2.9	0.04	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	11	18976208	24697116	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
1641927	Alcrsp10	Alcohol response QTL 10			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	11	8436674	53436674	Rat

Markers in Region

BF387369

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,861,495 - 23,861,668 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,266,715 - 24,266,887	NCBI	Rnor6.0
Rnor_5.0	11	27,894,504 - 27,894,676	UniSTS	Rnor5.0
Celera	11	23,700,703 - 23,700,875	UniSTS
RH 3.4 Map	11	113.0	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH130790

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,879,704 - 23,879,909 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,284,917 - 24,285,121	NCBI	Rnor6.0
Rnor_5.0	11	27,912,913 - 27,913,117	UniSTS	Rnor5.0
RGSC_v3.4	11	24,314,857 - 24,315,061	UniSTS	RGSC3.4
Celera	11	23,718,897 - 23,719,101	UniSTS
RH 3.4 Map	11	105.9	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH131165

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,833,877 - 23,834,085 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,238,082 - 24,238,289	NCBI	Rnor6.0
Rnor_5.0	11	27,867,424 - 27,867,631	UniSTS	Rnor5.0
Celera	11	23,673,294 - 23,673,501	UniSTS
RH 3.4 Map	11	102.3	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH133736

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	11	37,365,168 - 37,365,378 (+)	Marker Load Pipeline
mRatBN7.2	11	23,878,718 - 23,878,928 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,283,931 - 24,284,140	NCBI	Rnor6.0
Rnor_5.0	11	27,911,927 - 27,912,136	UniSTS	Rnor5.0
RGSC_v3.4	11	24,313,871 - 24,314,080	UniSTS	RGSC3.4
Celera	11	23,717,911 - 23,718,120	UniSTS
RH 3.4 Map	11	108.1	UniSTS
Cytogenetic Map	11	q11	UniSTS

RH143705

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,877,444 - 23,877,563 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,282,657 - 24,282,775	NCBI	Rnor6.0
Rnor_5.0	11	27,910,653 - 27,910,771	UniSTS	Rnor5.0
RGSC_v3.4	11	24,312,597 - 24,312,715	UniSTS	RGSC3.4
Celera	11	23,716,637 - 23,716,755	UniSTS
RH 3.4 Map	11	99.2	UniSTS
Cytogenetic Map	11	q11	UniSTS

BE117177

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,841,327 - 23,841,526 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,245,530 - 24,245,728	NCBI	Rnor6.0
Rnor_5.0	11	27,874,872 - 27,875,070	UniSTS	Rnor5.0
Celera	11	23,680,742 - 23,680,940	UniSTS
Cytogenetic Map	11	q11	UniSTS

JAM2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	23,876,888 - 23,877,010 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	24,282,101 - 24,282,222	NCBI	Rnor6.0
Rnor_5.0	11	27,910,097 - 27,910,218	UniSTS	Rnor5.0
RGSC_v3.4	11	24,312,041 - 24,312,162	UniSTS	RGSC3.4
Celera	11	23,716,081 - 23,716,202	UniSTS
Cytogenetic Map	11	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001034004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC110471	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC105305	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000046973 ⟹ ENSRNOP00000049564

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	23,831,106 - 23,880,063 (+)	Ensembl
Rnor_6.0 Ensembl	11	24,266,345 - 24,285,275 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094504 ⟹ ENSRNOP00000092709

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	23,860,422 - 23,880,063 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119888 ⟹ ENSRNOP00000096179

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	23,856,161 - 23,871,223 (+)	Ensembl

RefSeq Acc Id:

NM_001034004 ⟹ NP_001029176

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	37,317,560 - 37,366,517 (+)	NCBI
mRatBN7.2	11	23,831,106 - 23,880,067 (+)	NCBI
Rnor_6.0	11	24,235,310 - 24,285,279 (+)	NCBI
Rnor_5.0	11	27,864,652 - 27,913,275 (+)	NCBI
RGSC_v3.4	11	24,310,704 - 24,315,219 (+)	RGD
Celera	11	23,670,522 - 23,719,259 (+)	RGD

Sequence:

show sequence

GAGAGACTGACATCGCGACAGGACCCGCCCCTCTGCTTCCACCTCTCAGGGACCTCCTCTGCTC
CGCCACCCCGCGAAGTGCTGGGGGACCCAGCCGCCTGTCGCGCTCCTGCGGGGGGACCCTCGGC
TAGGCAGCCAGCTGGCGCCCGCGTAGATGGCGAGGAGCCCCCAAGGCCTTCTGCTGCTGCTACT
GCTGCACTACTTGATGGTCGCCCTGGACTATCATAAGGCAAATGGATTTTCTGCATCAAAAGAC
CACCGTCAAGAAGTTTCAGTAATAGAGTACCAAGAGGCTATTTTAGCTTGTAAAACCCCAAAGA
AGACCACTTCCTCCAGACTAGAGTGGAAGAAGCTAGGACAGGGTGTCTCCCTGGTCTACTATCA
ACAGGCTCTCCAAGGCGACTTTAAAGACCGTGCGGAGATGATAGATTTCAATATACGAATCAAG
AATGTCACAAGACATGATGCTGGAGAGTATCGCTGCGAAGTCAGCGCCCCGACTGAGCAAGGCC
AGAACCTGCAGGAAGATACAGTCATGCTGGAAGTCCTGGTGGCCCCCGCTGTCCCTTCATGTGA
AGTACCTACTTCCGTTATGAGTGGGAGTGTTGTGGAGCTACGGTGTCAAGAAAAAGAAGGAAAT
CCAGCCCCTGAGTACATATGGTTTAAAGATGGCACAAGTTTGCTGGGCAATCCAAAGGGCGGCG
CACACAGGAACAGCTCGTACACAATGAATACAAAATCTGGAACTCTGCAATTCAACATGATCTC
CAAGATGGACAGTGGAGAGTATTACTGTGAAGCCCGCAACTCTGTTGGGCATCGCAGGTGTCCC
GGGAAACGGATGCAAGTAGATGTTCTCAACATAAGTGGCATCATAGCAGCTGTGGTTGTTGTGG
CCTTCGTCATTTCTGCGTGTGGCCTTAGTATATGCTATGCTCAGAGAAAGGGCTACTTTTCAAA
AGAAACTTCCTTCCAGAAGGGCAGTCCTGCATCTAAAGCCACTACAATGAGCGAAAATGATTTC
AAGCACACAAAATCCTTTATAATTTAAAAGAATTCCACTTCTGAGATGCACCAAAACCACAGTT
GTCACACAAGTTATTAAACTATTGTAAACCTCTGCTTTGTCTTACATTTGCAAAGAGACGGACG
AAGAAACGAGAGTGGGAACTCATCATAACTGTTATGACCTCTAACTCACAAGAAATATTTTAAG
CAAAGTGTTCTTGCCATCACTAAAATACAATTTGGGATCTTATGTCTGACCTAAAGTGAAATGT
CTGAGGTTTTGAAATGCAAATGAATGTTAATTTTGGAGTTGACTAGATCATACTGACTGTAAAG
CTAACCCAAGAGGCAGGAATATACTGTATGTGCTCTGGTGAGAATGGCTTACATGTTCAGGAAA
TACTCTAACGAATGGAAACCCTGTTCGCAAAATTCCTACCAGAATCCTCTTCTTACCTCTAAAT
AATCCGGGTTCCTTTGCCCTGTGTCTCTGTATCCCGTAGGGGAATCCCAGGGCTGGGCCTTCCG
TCTAAGGGTTTGCACTTTATATTTTCTTTCACTTCTCAGAACCAAAAGCAACATGAAGGGAGCT
GCTGCCGCCAATTCCTGAGACTCTTGGAGGGGCTCAGTGACCTGGACATCAGAATGCACTACTA
GAACCTACACAGCTCCAGATCCTTTCTGTGCTTAAGTGGTGACCTTTTATCTGTCTCTAAAAGC
AATTCTGAACTGGGCTAGCTCCTCCCTGGTGAAGATACAGGGTTCCCAGCCTGCTTAGGATGAA
CAGGAGCACAGGGGAGAGAAACATTTGCCCCATGAGTAAGAGGTGGATGAACAAGCTCACTTTG
ACTCTTGATCCAGTCAAGGCACAGGAGAAACCGTGGCTGAAATGAGACAGGGGTCTAATGTCTT
CTGAACTGGTTATCCACAGAGGCCACCAACCAGCTAGTGTCAGATTAGATTCCCAGGGCTCAAC
AGAAAACCGGTCCTGCTGGGGGCTGGTTTACCCCTATTTAAAATAAAAAAAATGCAACTGAGGA
TGTCTAGCTCTGGGTAAATATGCACGAAAGGTCACTTACTTCCTTTACCGGCTTTGAACATGGT
CACGTTGGCTTTCTACCCAAAGGGCAAAGCAAAGTCTCAGGATTCTCATCAAAAGCAAACGGGG
TGAGTGGCCAGTGAGTACCTGGTAGTGATCTGGTCACCGGGGTGATGCCTACTGCCATACTGCT
CCCCTTTAACTTTGTGGCCTTGAATCTTTCCTAATCAGTAGACACCTTCCCAAAGGGCTGACTT
CTGTAAAGTGGCTCGGCCCTCAAGGTCAGATCCACACTTAACTGAGCCAGCAATCTACAAAGAA
CACCACAGTACATAATTCAGCCCACAGGGTTCTTGTTACAACCACTCATCTCTGTCACAACGTA
CAGTACAAGTGTGTCAGCGGTATAGGATTTGCCCACAGATCCAAGCTCCTCTCTCCTGGTAGCA
AATGACAAAGAAACACTGTGGTGTACAAGAAATCAGGGTAAATGTTGCCTGTGCCGTGACTAAG
AGATTTGCTTTGGTAGGAGGAGGCTGTCCTGCAGTGCCAAGCAGACGTACAACTCTCAAGGATG
TCTCTTCAGGCCCACATAGCATCACAAGACCAACTGCGTCAATTTAAATAACACAAATCCACAT
TGCGAGAGGACAATTACGTAGTGCCTTACCTTCACTAATAGAAGAAAAGCTTCCTTTTAAGACA
CTGAAGCCTAAAGGTTCATTTTAAGCAGTGTAGACACCTAACAAAGTCTGTGCCAAACACCTAT
TATACATCCTTAACTACTGTATACAGCTAAGCACAAGTCGCTGTGTAGAGAATGCGCTCTTCTG
CATAAAGGACCTGACTGTGCACACTAATCTCCTAGTTATTAAGTCTATCGGGAGTCACTGCCAT
GAAGACTTGTCCCTTTGCTGTTTTCTGAGACTTGAACTCTAACATTGTGTCAAAATTGAATTGT
AGTTTCTAGAACATGTTGATTTTATTTTTCCACAGTGAAAGTTTGATAAGGGTCTAGAAATTAT
GAGAGCAAGTTTTAGTATCGTCGCTGTTGTAACTAGATTCAACTTATTTTTAGTCAGGGTAGGG
GTTAACAGCTAAGTCTGGATGTTTATTTTTCAATACAACTTTACAAAGAACTTCCTTCATTCTA
CAACTCACTTTGTTTGATTAAAGTTCATGCTACAAAAATAGCTATGCACAGCTCAAGGTTTTAG
TCCCCTTCAACAGAGGGGGGAAGTCACTCACCTATTGTTCAGTAAAACCCAGGAAACTCCTCCC
TCCCTCACACCTGCACTTGTGAGGCAGCTCCAGCAGTTTCAAATCAAGGTCTCTCTGGTCTCTC
AGCTTGGACACCTGCCAACTTGTGTTTTGTGTGTGTCAGAGGTTGAGGATAAGGGAGTGCAGGC
CACTGTGAAGAGGAGCCTGTCGTTCTACAGTGGGTGACTGCTCGGCTTGGGTTTGCAGTGCAGT
TACGGAGGAGCTGGGGTCTTTATGAATACAGCCACCTGATCCACAGCTCACACATTTTCTTCAT
TTTAAATTTTCCAGTTCTCTACATTCTCTTCATCCTCAGTAACCCTGGCTCACCCACCCACCTA
CCCCGGCCCCAAACTTATCTTTGTAAAACTTTAACATTTAAAAACAAAAGGATACAACAACTTT
ATACACAACCAATCCAGAACCTGCTCTCTTTTGTTGCCTTATTATTCACCAAACTGAACTGTTT
GTTTTTACAATTTAGTCTGCCCTTTCCGATACATTTGTATTACATTCCTTAGATCGTTAGTCCT
CACCACAAGCTATGGAAATCCTATTTACTCCTGACAAGTCAAATTCAGCTCTCGTGGGACAGCG
TTCTCCCATTTCCTAGCAGTGAGTTTTGTCTCTCAAGTCCAATGGTATTTGGTTCTTTTGTGAT
ATTTATTGATTTCTGTGTTACAGTACAGGGAGGTATGTATGTGTGACATCTCCACCAACCTGAA
ACCCTGAAAAAGACCCATGTTGTACAGGTCTTCATAAACCCTAAGGTGTTTAATGGCATCTGAC
ATGAAAAAAGTTTCTAAAAACGCTGAATACCTGTGAAGCATAAAGAATGATTAAATGTAAGCAT
CTACTTAGAATATTAATAAAACATTGTATTCTGATACAAAAAAAAAAAAAAAAAAAAAAAAAAA
A

hide sequence

RefSeq Acc Id:

XM_039088608 ⟹ XP_038944536

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	37,316,287 - 37,366,517 (+)	NCBI
mRatBN7.2	11	23,830,820 - 23,880,071 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001029176	(Get FASTA)	NCBI Sequence Viewer
	XP_038944536	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI05306	(Get FASTA)	NCBI Sequence Viewer
	EDM10622	(Get FASTA)	NCBI Sequence Viewer
	EDM10623	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000049564
	ENSRNOP00000049564.6
	ENSRNOP00000092709.1
	ENSRNOP00000096179.1

RefSeq Acc Id:	NP_001029176 ⟸ NM_001034004
- Peptide Label:	precursor
- UniProtKB:	Q3MHC0 (UniProtKB/TrEMBL), F1M065 (UniProtKB/TrEMBL), A6JL57 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARSPQGLLLLLLLHYLMVALDYHKANGFSASKDHRQEVSVIEYQEAILACKTPKKTTSSRLEW KKLGQGVSLVYYQQALQGDFKDRAEMIDFNIRIKNVTRHDAGEYRCEVSAPTEQGQNLQEDTVM LEVLVAPAVPSCEVPTSVMSGSVVELRCQEKEGNPAPEYIWFKDGTSLLGNPKGGAHRNSSYTM NTKSGTLQFNMISKMDSGEYYCEARNSVGHRRCPGKRMQVDVLNISGIIAAVVVVAFVISACGL SICYAQRKGYFSKETSFQKGSPASKATTMSENDFKHTKSFII hide sequence

Ensembl Acc Id:

ENSRNOP00000049564 ⟸ ENSRNOT00000046973

RefSeq Acc Id:	XP_038944536 ⟸ XM_039088608
- Peptide Label:	isoform X1
- UniProtKB:	A6JL57 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000096179 ⟸ ENSRNOT00000119888

Ensembl Acc Id:

ENSRNOP00000092709 ⟸ ENSRNOT00000094504

Protein Domains

Ig-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M065-F1-model_v2	AlphaFold	F1M065	1-257	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561692	AgrOrtholog
BioCyc Gene	G2FUF-22083	BioCyc
Ensembl Genes	ENSRNOG00000042848	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000046973	ENTREZGENE
	ENSRNOT00000046973.6	UniProtKB/TrEMBL
	ENSRNOT00000094504.1	UniProtKB/TrEMBL
	ENSRNOT00000119888.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7192610	IMAGE-MGC_LOAD
InterPro	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/TrEMBL
	JAM2	UniProtKB/TrEMBL
KEGG Report	rno:619374	UniProtKB/TrEMBL
MGC_CLONE	MGC:124988	IMAGE-MGC_LOAD
NCBI Gene	619374	ENTREZGENE
PANTHER	JUNCTIONAL ADHESION MOLECULE B	UniProtKB/TrEMBL
	PTHR44663	UniProtKB/TrEMBL
Pfam	Ig_3	UniProtKB/TrEMBL
	V-set	UniProtKB/TrEMBL
PhenoGen	Jam2	PhenoGen
PROSITE	IG_LIKE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000042848	RatGTEx
SMART	IGc2	UniProtKB/TrEMBL
	IGv	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A8I6AEF6_RAT	UniProtKB/TrEMBL
	A0A8I6ANZ9_RAT	UniProtKB/TrEMBL
	A6JL57	ENTREZGENE, UniProtKB/TrEMBL
	A6JL58_RAT	UniProtKB/TrEMBL
	F1M065	ENTREZGENE
	Q3MHC0	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F1M065	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-11-06	Jam2	junctional adhesion molecule 2	Jam2	junction adhesion molecule 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	Jam2	junction adhesion molecule 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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