Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ccdc68 | Rat | (-)-demecolcine | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of CCDC68 mRNA | CTD | PMID:23649840 | Ccdc68 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Ccdc68 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCDC68 mRNA | CTD | PMID:22206623 | Ccdc68 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CCDC68 mRNA | CTD | PMID:22206623 | Ccdc68 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of CCDC68 mRNA | CTD | PMID:30723492 | Ccdc68 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of CCDC68 mRNA | CTD | PMID:17557909 | Ccdc68 | Rat | 17beta-estradiol | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of CCDC68 mRNA | CTD | PMID:31614463 | Ccdc68 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CCDC68 mRNA | CTD | PMID:21632981 | Ccdc68 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CCDC68 mRNA | CTD | PMID:21570461 | Ccdc68 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | bisphenol S results in increased expression of CCDC68 mRNA | CTD | PMID:30951980 | Ccdc68 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of CCDC68 mRNA | CTD | PMID:31881176 | Ccdc68 | Rat | acrolein | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CCDC68 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CCDC68 mRNA | CTD | PMID:32699268 | Ccdc68 | Rat | aflatoxin B1 | affects expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of CCDC68 protein | CTD | PMID:20106945 | Ccdc68 | Rat | aflatoxin B1 | increases methylation | ISO | CCDC68 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of CCDC68 intron | CTD | PMID:30157460 | Ccdc68 | Rat | aflatoxin B1 | decreases methylation | ISO | CCDC68 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of CCDC68 gene | CTD | PMID:27153756 | Ccdc68 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of CCDC68 mRNA | CTD | PMID:23630614 and PMID:25378103 | Ccdc68 | Rat | aflatoxin B1 | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of CCDC68 mRNA | CTD | PMID:21632981 | Ccdc68 | Rat | all-trans-retinoic acid | multiple interactions | ISO | Ccdc68 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CCDC68 mRNA | CTD | PMID:36189433 | Ccdc68 | Rat | alpha-pinene | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CCDC68 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CCDC68 mRNA | CTD | PMID:32699268 | Ccdc68 | Rat | arsane | increases methylation | ISO | CCDC68 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of CCDC68 gene and Arsenic results in increased methylation of CCDC68 promoter | CTD | PMID:21291286 and PMID:24525453 | Ccdc68 | Rat | arsane | decreases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Arsenic results in decreased expression of CCDC68 mRNA | CTD | PMID:19654921 | Ccdc68 | Rat | arsenic atom | increases methylation | ISO | CCDC68 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of CCDC68 gene and Arsenic results in increased methylation of CCDC68 promoter | CTD | PMID:21291286 and PMID:24525453 | Ccdc68 | Rat | arsenic atom | decreases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Arsenic results in decreased expression of CCDC68 mRNA | CTD | PMID:19654921 | Ccdc68 | Rat | benzo[a]pyrene | decreases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of CCDC68 mRNA | CTD | PMID:19770486 | Ccdc68 | Rat | benzo[a]pyrene | increases methylation | ISO | Ccdc68 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of CCDC68 intron | CTD | PMID:27901495 | Ccdc68 | Rat | benzo[a]pyrene | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of CCDC68 mRNA | CTD | PMID:20106945 and PMID:21632981 | Ccdc68 | Rat | benzo[a]pyrene | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of CCDC68 mRNA | CTD | PMID:22228805 | Ccdc68 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | Ccdc68 | Rat | benzo[b]fluoranthene | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of CCDC68 mRNA | CTD | PMID:26377693 | Ccdc68 | Rat | benzo[e]pyrene | increases methylation | ISO | CCDC68 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of CCDC68 intron | CTD | PMID:30157460 | Ccdc68 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CCDC68 mRNA | CTD | PMID:25181051 | Ccdc68 | Rat | bisphenol A | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | bisphenol A results in increased expression of CCDC68 mRNA | CTD | PMID:34585602 | Ccdc68 | Rat | bisphenol F | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | bisphenol F results in increased expression of CCDC68 mRNA | CTD | PMID:30951980 | Ccdc68 | Rat | carbon nanotube | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of CCDC68 mRNA | CTD | PMID:25554681 | Ccdc68 | Rat | CGP 52608 | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CCDC68 gene] | CTD | PMID:28238834 | Ccdc68 | Rat | choline | multiple interactions | ISO | Ccdc68 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC68 mRNA | CTD | PMID:20938992 | Ccdc68 | Rat | cisplatin | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of CCDC68 mRNA | CTD | PMID:27392435 | Ccdc68 | Rat | cisplatin | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of CCDC68 mRNA | CTD | PMID:27392435 | Ccdc68 | Rat | copper(II) sulfate | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of CCDC68 mRNA | CTD | PMID:19549813 | Ccdc68 | Rat | crocidolite asbestos | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in increased expression of CCDC68 mRNA | CTD | PMID:18687144 | Ccdc68 | Rat | crocidolite asbestos | decreases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of CCDC68 mRNA | CTD | PMID:29279043 | Ccdc68 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of CCDC68 mRNA | CTD | PMID:27523638 | Ccdc68 | Rat | cyclosporin A | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of CCDC68 mRNA | CTD | PMID:20106945 | Ccdc68 | Rat | cyclosporin A | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of CCDC68 mRNA | CTD | PMID:25562108 | Ccdc68 | Rat | dicrotophos | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of CCDC68 mRNA | CTD | PMID:28302478 | Ccdc68 | Rat | dioxygen | multiple interactions | ISO | Ccdc68 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CCDC68 mRNA | CTD | PMID:30529165 | Ccdc68 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of CCDC68 mRNA | CTD | PMID:33729688 | Ccdc68 | Rat | dorsomorphin | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ccdc68 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CCDC68 mRNA | CTD | PMID:29391264 | Ccdc68 | Rat | ethylparaben | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of CCDC68 mRNA | CTD | PMID:37690743 | Ccdc68 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of CCDC68 mRNA | CTD | PMID:24793618 | Ccdc68 | Rat | folic acid | multiple interactions | ISO | Ccdc68 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | Ccdc68 | Rat | formaldehyde | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of CCDC68 mRNA | CTD | PMID:23649840 | Ccdc68 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of CCDC68 gene | CTD | PMID:22079235 | Ccdc68 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of CCDC68 mRNA | CTD | PMID:25539665 and PMID:26194646 | Ccdc68 | Rat | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of CCDC68 mRNA | CTD | PMID:24915197 | Ccdc68 | Rat | L-methionine | multiple interactions | ISO | Ccdc68 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCDC68 mRNA | CTD | PMID:20938992 | Ccdc68 | Rat | leflunomide | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | leflunomide results in increased expression of CCDC68 mRNA | CTD | PMID:28988120 | Ccdc68 | Rat | Licochalcone B | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | licochalcone B results in decreased expression of CCDC68 mRNA | CTD | PMID:33647349 | Ccdc68 | Rat | methapyrilene | increases methylation | ISO | CCDC68 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of CCDC68 intron | CTD | PMID:30157460 | Ccdc68 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of CCDC68 mRNA | CTD | PMID:30467583 | Ccdc68 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Ccdc68 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CCDC68 mRNA | CTD | PMID:36189433 | Ccdc68 | Rat | N-nitrosodiethylamine | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of CCDC68 mRNA | CTD | PMID:24535843 | Ccdc68 | Rat | nickel sulfate | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of CCDC68 mRNA | CTD | PMID:22714537 | Ccdc68 | Rat | niclosamide | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Niclosamide results in decreased expression of CCDC68 mRNA | CTD | PMID:36318118 | Ccdc68 | Rat | orphenadrine | affects expression | EXP | | 6480464 | Orphenadrine affects the expression of CCDC68 mRNA | CTD | PMID:23665939 | Ccdc68 | Rat | ozone | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CCDC68 mRNA more ... | CTD | PMID:32699268 | Ccdc68 | Rat | paracetamol | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CCDC68 mRNA | CTD | PMID:26690555 | Ccdc68 | Rat | paracetamol | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of CCDC68 mRNA | CTD | PMID:29067470 | Ccdc68 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of CCDC68 mRNA | CTD | PMID:37995155 | Ccdc68 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CCDC68 mRNA | CTD | PMID:27153767 | Ccdc68 | Rat | phenylmercury acetate | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of CCDC68 mRNA | CTD | PMID:26272509 | Ccdc68 | Rat | phenylmercury acetate | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC68 mRNA | CTD | PMID:27188386 | Ccdc68 | Rat | pirinixic acid | multiple interactions | ISO | Ccdc68 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CCDC68 mRNA | CTD | PMID:19710929 | Ccdc68 | Rat | potassium chromate | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of CCDC68 mRNA | CTD | PMID:22714537 | Ccdc68 | Rat | potassium dichromate | decreases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of CCDC68 mRNA | CTD | PMID:23608068 | Ccdc68 | Rat | progesterone | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Progesterone results in increased expression of CCDC68 mRNA | CTD | PMID:21795739 | Ccdc68 | Rat | quercetin | decreases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of CCDC68 mRNA | CTD | PMID:21632981 | Ccdc68 | Rat | SB 431542 | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ccdc68 | Rat | sodium arsenite | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of CCDC68 mRNA | CTD | PMID:22714537 | Ccdc68 | Rat | sodium arsenite | affects expression | ISO | CCDC68 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of CCDC68 mRNA | CTD | PMID:29319823 | Ccdc68 | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of CCDC68 mRNA | CTD | PMID:25993096 | Ccdc68 | Rat | tetraphene | affects expression | ISO | Ccdc68 (Mus musculus) | 6480464 | benz(a)anthracene affects the expression of CCDC68 mRNA | CTD | PMID:26377693 | Ccdc68 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CCDC68 mRNA | CTD | PMID:23411599 and PMID:34492290 | Ccdc68 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of CCDC68 mRNA | CTD | PMID:33387578 | Ccdc68 | Rat | trichostatin A | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of CCDC68 mRNA | CTD | PMID:24935251 | Ccdc68 | Rat | triptonide | increases expression | ISO | Ccdc68 (Mus musculus) | 6480464 | triptonide results in increased expression of CCDC68 mRNA | CTD | PMID:33045310 | Ccdc68 | Rat | valproic acid | decreases methylation | ISO | CCDC68 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of CCDC68 gene | CTD | PMID:29154799 | Ccdc68 | Rat | valproic acid | increases expression | ISO | CCDC68 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CCDC68 mRNA | CTD | PMID:23179753 more ... | Ccdc68 | Rat | valproic acid | multiple interactions | ISO | CCDC68 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC68 mRNA | CTD | PMID:27188386 | |