Or4q3 (olfactory receptor family 4 subfamily Q member 3) - Rat Genome Database

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Gene: Or4q3 (olfactory receptor family 4 subfamily Q member 3) Rattus norvegicus
Analyze
Symbol: Or4q3 (Ensembl: AC122990.1)
Name: olfactory receptor family 4 subfamily Q member 3
RGD ID: 1561412
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR4Q3 (olfactory receptor family 4 subfamily Q member 3); INTERACTS WITH bisphenol A; indole-3-methanol; testosterone.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC498490; olfactory receptor 1878; olfactory receptor 4Q3; olfactory receptor 735, pseudogene; olfactory receptor, family 4, subfamily Q, member 3; Olr1878; Olr735-ps; RGD1561412; similar to olfactory receptor Olfr735
RGD Orthologs
Human
Mouse
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,004,612 - 26,012,181 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1526,004,612 - 26,009,053 (-)EnsemblGRCr8
mRatBN7.21523,531,029 - 23,535,992 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01527,163,525 - 27,165,024 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01531,090,058 - 31,095,021 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41526,056,452 - 26,061,415 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1523,862,913 - 23,864,412 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or4q3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,004,612 - 26,012,181 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1526,004,612 - 26,009,053 (-)EnsemblGRCr8
mRatBN7.21523,531,029 - 23,535,992 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01527,163,525 - 27,165,024 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01531,090,058 - 31,095,021 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41526,056,452 - 26,061,415 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1523,862,913 - 23,864,412 (-)NCBICelera
Cytogenetic Map15p14NCBI
OR4Q3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381419,743,571 - 19,752,334 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1419,743,571 - 19,749,469 (+)Ensemblhg38GRCh38
GRCh371420,211,730 - 20,217,628 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361419,285,427 - 19,286,368 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341419,285,426 - 19,286,368NCBI
Celera1481,050 - 81,991 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef14341,898 - 342,839 (+)NCBIHuRef
CHM1_11420,217,108 - 20,218,049 (+)NCBICHM1_1
T2T-CHM13v2.01413,918,508 - 13,962,426 (+)NCBIT2T-CHM13v2.0
Or4q3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391450,582,833 - 50,583,897 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1450,580,069 - 50,586,329 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381450,345,376 - 50,346,440 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,342,612 - 50,348,872 (-)Ensemblmm10GRCm38
MGSCv371450,965,051 - 50,966,115 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361449,267,327 - 49,268,391 (-)NCBIMGSCv36mm8
Celera1446,582,015 - 46,583,079 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.06NCBI
LOC102023301
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955550635,023 - 635,988 (-)NCBIChiLan1.0ChiLan1.0
OR4Q3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,350,088 - 17,351,053 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,350,095 - 17,354,349 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1517,752,015 - 17,752,962 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01517,606,617 - 17,607,564 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1517,606,617 - 17,607,908 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,296,560 - 17,297,507 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,344,456 - 17,345,403 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01517,476,560 - 17,477,507 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101963790
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864077,146,240 - 77,147,190 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936877127,397 - 128,395 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936877127,397 - 128,347 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100155779
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1778,951,683 - 78,952,669 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27133,596,076 - 133,597,023 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103231329
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12920,655,623 - 20,657,296 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2920,656,004 - 20,656,942 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605925,846,377 - 25,847,318 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101714835
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248255,487,473 - 5,488,465 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Or4q3
24 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_063274950   ⟹   XP_063131020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,004,612 - 26,012,181 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063131020 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000096264.1
RefSeq Acc Id: XP_063131020   ⟸   XM_063274950
- UniProtKB: A0A8I6B3X7 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561412 AgrOrtholog
BioCyc Gene G2FUF-14084 BioCyc
Ensembl Genes ENSRNOG00000033642 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041248.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
NCBI Gene 498490 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4q3 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033642 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6B3X7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or4q3  olfactory receptor family 4 subfamily Q member 3  Olr1878  olfactory receptor 1878  Symbol and Name Changed 1299863 APPROVED
2013-03-05 Olr1878  olfactory receptor 1878  Olr735-ps  olfactory receptor 735, pseudogene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-06-08 Olr735-ps  olfactory receptor 735, pseudogene  Or4q3  olfactory receptor, family 4, subfamily Q, member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561412  similar to olfactory receptor Olfr735   RGD1561412_predicted  similar to olfactory receptor Olfr735 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561412_predicted  similar to olfactory receptor Olfr735 (predicted)  LOC498490  similar to olfactory receptor Olfr735  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498490  similar to olfactory receptor Olfr735      Symbol and Name status set to provisional 70820 PROVISIONAL