Slc25a5-ps11 (solute carrier family 25 member 5, pseudogene 11) - Rat Genome Database

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Gene: Slc25a5-ps11 (solute carrier family 25 member 5, pseudogene 11) Rattus norvegicus
Analyze
Symbol: Slc25a5-ps11
Name: solute carrier family 25 member 5, pseudogene 11
RGD ID: 1560896
Description: Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in membrane and mitochondrion. Orthologous to several human genes including SLC25A5 (solute carrier family 25 member 5); PARTICIPATES IN calcium/calcium-mediated signaling pathway; Huntington's disease pathway; Parkinson's disease pathway; INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: adenine nucleotide translocator), member 6; ADP/ATP translocase 2-like; LOC498885; RGD1560896; similar to solute carrier family 25, member 5; Slc25a6; solute carrier family 25 (mitochondrial carrier; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 6; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; solute carrier family 25 member 6
RGD Orthologs
Human
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Functional Gene: Slc25a5  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,846,358 - 70,847,597 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1870,846,358 - 70,847,597 (+)EnsemblGRCr8
mRatBN7.21868,571,222 - 68,572,461 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1868,571,300 - 68,572,199 (+)EnsemblmRatBN7.2
Rnor_6.01870,959,872 - 70,961,040 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,959,887 - 70,960,786 (+)Ensemblrn6Rnor6.0
Rnor_5.01870,099,119 - 70,100,285 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41871,853,216 - 71,854,115 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1866,746,244 - 66,747,412 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (ISO)
mitochondrion  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Slc25a5-ps11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,846,358 - 70,847,597 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1870,846,358 - 70,847,597 (+)EnsemblGRCr8
mRatBN7.21868,571,222 - 68,572,461 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1868,571,300 - 68,572,199 (+)EnsemblmRatBN7.2
Rnor_6.01870,959,872 - 70,961,040 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,959,887 - 70,960,786 (+)Ensemblrn6Rnor6.0
Rnor_5.01870,099,119 - 70,100,285 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41871,853,216 - 71,854,115 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1866,746,244 - 66,747,412 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
SLC25A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38Y1,386,152 - 1,392,113 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38X1,386,152 - 1,392,113 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblY1,386,152 - 1,392,113 (-)Ensemblhg38GRCh38
GRCh38.p14 EnsemblX1,386,152 - 1,392,113 (-)Ensemblhg38GRCh38
GRCh37X1,505,045 - 1,511,006 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37Y1,455,045 - 1,461,006 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X1,465,045 - 1,470,998 (-)NCBIBuild 36Build 36hg18NCBI36
Build 36Y1,465,045 - 1,470,998 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34Y1,548,871 - 1,554,821NCBI
CeleraX5,786,374 - 5,792,489 (-)NCBICelera
Cytogenetic MapX;YNCBI
CHM1_1X1,535,623 - 1,541,618 (-)NCBICHM1_1
T2T-CHM13v2.0X1,229,798 - 1,235,760 (-)NCBIT2T-CHM13v2.0
T2T-CHM13v2.0Y1,249,921 - 1,256,001 (-)NCBIT2T-CHM13v2.0
LOC129395394
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X1,267,586 - 1,276,226 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1-v2Y45,668,078 - 45,674,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X1,271,231 - 1,277,161 (-)NCBINHGRI_mPanPan1
NHGRI_mPanPan1Y1,280,680 - 1,286,632 (-)NCBINHGRI_mPanPan1
SLC25A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X912,937 - 916,156 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX912,938 - 915,257 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX853,949 - 857,445 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X824,243 - 827,752 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX824,244 - 827,827 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X816,189 - 819,544 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X832,850 - 836,344 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X868,569 - 872,069 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc25a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404953581,561 - 583,317 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366443,793,434 - 3,795,182 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A6
(Sus scrofa - pig)		 No map positions available.
SLC25A6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660561,371,788 - 1,377,522 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624834653,599 - 657,556 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624834654,552 - 657,580 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc25a5-ps11
6 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000046606
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185449080186134022Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)186438376279484311Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184562030686134022Rat
7794793Mcs34Mammary carcinoma susceptibility QTL 341.54mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)186563556785897775Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184891573786134022Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184891573786134022Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183199089176990891Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184562030686134022Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186198220476619168Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)186144685386134022Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185449080176272247Rat
2312600Bp341Blood pressure QTL 3410.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186160038472538878Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183199089176990891Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185079521286134022Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183152278376522783Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186289225779484461Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185782524385493247Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183161050577371277Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)183199089176990891Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184891573786134022Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)186584644786134022Rat
1598832Glom11Glomerulus QTL 112.9kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)185326667186134022Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183199089176990891Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)185079521286134022Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186289225779484461Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183161050572538878Rat

Markers in Region
D12Got44  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,558,585 - 68,558,759 (+)MAPPERmRatBN7.2
Rnor_6.01870,947,180 - 70,947,353NCBIRnor6.0
Rnor_5.01870,086,428 - 70,086,601UniSTSRnor5.0
RGSC_v3.41871,840,508 - 71,840,682RGDRGSC3.4
RGSC_v3.41871,840,509 - 71,840,682UniSTSRGSC3.4
Celera1866,733,576 - 66,733,749UniSTS
RGSC_v3.11871,913,710 - 71,913,883RGD
RH 3.4 Map12307.12RGD
RH 3.4 Map12307.12UniSTS
Cytogenetic Map18q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 6 41 115 59 58 27 76 27 6 257 141 4 101 69 72 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000046606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,846,358 - 70,847,597 (+)Ensembl
mRatBN7.2 Ensembl1868,571,300 - 68,572,199 (+)Ensembl
Rnor_6.0 Ensembl1870,959,887 - 70,960,786 (+)Ensembl
RefSeq Acc Id: NM_001408903   ⟹   NP_001395832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,846,358 - 70,847,597 (+)NCBI
mRatBN7.21868,571,222 - 68,572,461 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001395832 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001395832   ⟸   NM_001408903

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560896 AgrOrtholog
BioCyc Gene G2FUF-6996 BioCyc
Ensembl Genes ENSRNOG00000042387 Ensembl, ENTREZGENE
NCBI Gene 498885 ENTREZGENE
PhenoGen Slc25a5-ps11 PhenoGen
RatGTEx ENSRNOG00000042387 RatGTEx


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-20 Slc25a5-ps11  solute carrier family 25 member 5, pseudogene 11  Slc25a6  solute carrier family 25 member 6  Name and Symbol and Type changed (type changed from [protein-coding] to [pseudo]) 629549 APPROVED
2016-02-24 Slc25a6  solute carrier family 25 member 6  Slc25a6  solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Slc25a6  solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6  RGD1560896  similar to solute carrier family 25, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1560896  similar to solute carrier family 25, member 5   RGD1560896_predicted  similar to solute carrier family 25, member 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560896_predicted  similar to solute carrier family 25, member 5 (predicted)  LOC498885  similar to solute carrier family 25, member 5  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498885  similar to solute carrier family 25, member 5      Symbol and Name status set to provisional 70820 PROVISIONAL