Dnah5 (dynein, axonemal, heavy chain 5) - Rat Genome Database

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Gene: Dnah5 (dynein, axonemal, heavy chain 5) Rattus norvegicus
Analyze
Symbol: Dnah5
Name: dynein, axonemal, heavy chain 5
RGD ID: 1560828
Description: Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement involved in cell motility and outer dynein arm assembly. Predicted to act upstream of or within several processes, including epithelial cilium movement involved in extracellular fluid movement; flagellated sperm motility; and lateral ventricle development. Predicted to be located in 9+0 motile cilium and axoneme. Predicted to be part of outer dynein arm. Predicted to be active in 9+2 motile cilium. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 3. Orthologous to human DNAH5 (dynein axonemal heavy chain 5); INTERACTS WITH ammonium chloride; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: axonemal beta dynein heavy chain 5; ciliary dynein heavy chain 5; DLP5; Dnahc5; Dnahc8; dynein axonemal heavy chain 5; dynein heavy chain; dynein heavy chain 5, axonemal; dynein-like prot ein 5; dynein-like protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8280,668,182 - 80,985,918 (+)NCBIGRCr8
mRatBN7.2278,937,788 - 79,255,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,937,800 - 79,254,890 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0280,947,730 - 81,143,997 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0281,159,060 - 81,337,560 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,948,658 - 81,143,447 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02100,825,558 - 101,002,352 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02100,627,199 - 100,809,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4280,126,196 - 80,390,674 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera274,613,354 - 74,877,574 (+)NCBICelera
Cytogenetic Map2q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
9+0 motile cilium  (IEA,ISO)
9+2 motile cilium  (IBA,IEA,ISO)
axonemal dynein complex  (ISO)
axoneme  (IEA,ISO,ISS)
cytoplasm  (ISO)
dynein complex  (IEA)
extracellular region  (IEA)
microtubule  (IEA)
motile cilium  (IEA,ISO,ISS)
outer dynein arm  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry. Olbrich H, etal., Nat Genet. 2002 Feb;30(2):143-4. Epub 2002 Jan 14.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Identification and molecular evolution of new dynein-like protein sequences in rat brain. Tanaka Y, etal., J Cell Sci 1995 May;108 ( Pt 5):1883-93.
9. Multiple mouse chromosomal loci for dynein-based motility. Vaughan KT, etal., Genomics 1996 Aug 15;36(1):29-38.
Additional References at PubMed
PMID:11062149   PMID:11912187   PMID:15750039   PMID:16492982   PMID:16627867   PMID:17515466   PMID:18492703   PMID:18950741   PMID:19222235   PMID:22499950   PMID:23261302   PMID:23849778  
PMID:24203976   PMID:25192045   PMID:25807483   PMID:26387594   PMID:26909801   PMID:27353389   PMID:28289722   PMID:29916806   PMID:31178125   PMID:32357304  


Genomics

Comparative Map Data
Dnah5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8280,668,182 - 80,985,918 (+)NCBIGRCr8
mRatBN7.2278,937,788 - 79,255,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,937,800 - 79,254,890 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0280,947,730 - 81,143,997 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0281,159,060 - 81,337,560 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,948,658 - 81,143,447 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02100,825,558 - 101,002,352 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02100,627,199 - 100,809,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4280,126,196 - 80,390,674 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera274,613,354 - 74,877,574 (+)NCBICelera
Cytogenetic Map2q22NCBI
DNAH5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38513,690,328 - 14,011,818 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl513,690,328 - 14,011,818 (-)EnsemblGRCh38hg38GRCh38
GRCh37513,690,437 - 13,944,797 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36513,745,039 - 13,997,589 (-)NCBINCBI36Build 36hg18NCBI36
Build 34513,745,038 - 13,997,589NCBI
Celera513,715,619 - 13,969,162 (-)NCBICelera
Cytogenetic Map5p15.2NCBI
HuRef513,661,841 - 13,916,517 (-)NCBIHuRef
CHM1_1513,690,308 - 13,944,156 (-)NCBICHM1_1
T2T-CHM13v2.0513,627,358 - 13,948,914 (-)NCBIT2T-CHM13v2.0
Dnah5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391528,155,000 - 28,472,191 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1528,203,898 - 28,472,198 (+)EnsemblGRCm39 Ensembl
GRCm381528,154,854 - 28,472,045 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1528,203,752 - 28,472,052 (+)EnsemblGRCm38mm10GRCm38
MGSCv371528,133,521 - 28,401,800 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361528,148,355 - 28,415,259 (+)NCBIMGSCv36mm8
Celera1528,952,222 - 29,215,703 (+)NCBICelera
Cytogenetic Map15B1NCBI
cM Map1510.9NCBI
Dnah5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554263,106,410 - 3,353,502 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554263,105,631 - 3,406,587 (-)NCBIChiLan1.0ChiLan1.0
DNAH5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2413,914,183 - 14,246,527 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1512,067,789 - 12,400,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0513,989,114 - 14,316,855 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1513,833,309 - 14,159,871 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl513,851,391 - 14,093,358 (-)Ensemblpanpan1.1panPan2
DNAH5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.134816,088 - 1,040,052 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl34805,455 - 1,038,273 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha345,235,833 - 5,530,906 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.034649,213 - 944,561 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl34649,200 - 944,407 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.134663,314 - 958,206 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.034661,426 - 955,971 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.034904,270 - 1,199,480 (+)NCBIUU_Cfam_GSD_1.0
Dnah5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213233,673,500 - 233,953,547 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366652,314,175 - 2,545,579 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366652,267,272 - 2,545,765 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAH5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl163,114,273 - 3,430,341 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1163,114,267 - 3,366,189 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2163,466,224 - 3,706,296 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAH5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1413,401,980 - 13,718,900 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl413,401,092 - 13,652,755 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606414,822,926 - 15,141,477 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnah5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475110,799,892 - 11,050,403 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475110,799,102 - 11,110,180 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dnah5
2544 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:263
Count of miRNA genes:177
Interacting mature miRNAs:200
Transcripts:ENSRNOT00000017372, ENSRNOT00000074252, ENSRNOT00000074689
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)259846005104846005Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)243162366111362592Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)276539322102785628Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)259324377103795077Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
7411551Bw131Body weight QTL 13129.60.001body mass (VT:0001259)body weight gain (CMO:0000420)267942638112942638Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)27478666494359546Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)278665616143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)259324719102755241Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)259324377103795077Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)264366971109366971Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat

Markers in Region
D2Uwm31  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2278,997,662 - 78,997,855 (+)MAPPERmRatBN7.2
Rnor_6.0280,964,992 - 80,965,184NCBIRnor6.0
Rnor_5.02100,630,972 - 100,631,164UniSTSRnor5.0
RGSC_v3.4280,130,990 - 80,131,182UniSTSRGSC3.4
RGSC_v3.1280,075,951 - 80,076,144RGD
Celera274,630,894 - 74,631,086UniSTS
Cytogenetic Map2q22UniSTS
AU048434  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2279,046,420 - 79,046,719 (+)MAPPERmRatBN7.2
Rnor_6.0281,013,978 - 81,014,276NCBIRnor6.0
Rnor_5.02100,679,921 - 100,680,219UniSTSRnor5.0
RGSC_v3.4280,180,056 - 80,180,354UniSTSRGSC3.4
Celera274,679,580 - 74,679,878UniSTS
Cytogenetic Map2q22UniSTS
AU049271  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2279,035,595 - 79,035,812 (+)MAPPERmRatBN7.2
Rnor_6.0281,003,174 - 81,003,390NCBIRnor6.0
Rnor_5.02100,669,154 - 100,669,370UniSTSRnor5.0
RGSC_v3.4280,168,927 - 80,169,143UniSTSRGSC3.4
Celera274,668,824 - 74,669,040UniSTS
Cytogenetic Map2q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7
Low 13 1 8 8 59 11 4 8
Below cutoff 28 27 13 9 13 15 21 27

Sequence


RefSeq Acc Id: ENSRNOT00000074689   ⟹   ENSRNOP00000065896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl278,980,771 - 79,237,702 (+)Ensembl
Rnor_6.0 Ensembl280,948,658 - 81,143,447 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098157   ⟹   ENSRNOP00000085962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl278,980,771 - 79,254,890 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101312   ⟹   ENSRNOP00000078949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl278,937,800 - 79,254,890 (+)Ensembl
RefSeq Acc Id: NM_001419569   ⟹   NP_001406498
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,711,186 - 80,985,914 (+)NCBI
mRatBN7.2278,980,794 - 79,255,551 (+)NCBI
RefSeq Acc Id: XM_039103563   ⟹   XP_038959491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,668,182 - 80,985,918 (+)NCBI
mRatBN7.2278,937,788 - 79,254,088 (+)NCBI
RefSeq Acc Id: XM_063281529   ⟹   XP_063137599
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,711,002 - 80,985,918 (+)NCBI
RefSeq Acc Id: ENSRNOP00000065896   ⟸   ENSRNOT00000074689
RefSeq Acc Id: XP_038959491   ⟸   XM_039103563
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G2L4 (UniProtKB/TrEMBL),   A0A8L2QZ25 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000078949   ⟸   ENSRNOT00000101312
RefSeq Acc Id: ENSRNOP00000085962   ⟸   ENSRNOT00000098157
RefSeq Acc Id: NP_001406498   ⟸   NM_001419569
- UniProtKB: A0A8I6A195 (UniProtKB/TrEMBL),   A0A8L2QZ25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137599   ⟸   XM_063281529
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QZ25 (UniProtKB/TrEMBL)
Protein Domains
AAA+ ATPase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560828 AgrOrtholog
BioCyc Gene G2FUF-53908 BioCyc
Ensembl Genes ENSRNOG00000048363 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074689.3 UniProtKB/TrEMBL
  ENSRNOT00000098157.1 UniProtKB/TrEMBL
  ENSRNOT00000101312.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.2620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.472.130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.8.1220 UniProtKB/TrEMBL
  1.10.8.710 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/TrEMBL
  1.20.1270.280 UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.1120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.920.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.920.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.140.1060 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/TrEMBL
  DHC_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAH3_AAA_lid_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_2_C UniProtKB/Swiss-Prot
  Dynein_2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA5_ext UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_D6_P-loop UniProtKB/TrEMBL
  Dynein_heavy_dom-1 UniProtKB/Swiss-Prot
  Dynein_heavy_dom-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_tail UniProtKB/TrEMBL
  Dynein_linker_3 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 294854 ENTREZGENE
PANTHER DYNEIN AXONEMAL HEAVY CHAIN 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MALE FERTILITY FACTOR KL5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AAA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  DHC_N1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DHC_N2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA_lid UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_heavy UniProtKB/TrEMBL
  PF12777 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnah5 PhenoGen
RatGTEx ENSRNOG00000048363 RatGTEx
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A195 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G2L4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QZ25 ENTREZGENE, UniProtKB/TrEMBL
  DYH5_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Dnah5  dynein, axonemal, heavy chain 5  Dnahc5  dynein, axonemal, heavy chain 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dnahc5  dynein, axonemal, heavy chain 5  DLP5  dynein-like prot ein 5  Symbol and Name updated 1299863 APPROVED
2006-02-09 DLP5  dynein-like prot ein 5      Symbol and Name status set to provisional 70820 PROVISIONAL