Dnajc19 (DnaJ heat shock protein family (Hsp40) member C19) - Rat Genome Database

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Pathways
Gene: Dnajc19 (DnaJ heat shock protein family (Hsp40) member C19) Rattus norvegicus
Analyze
Symbol: Dnajc19
Name: DnaJ heat shock protein family (Hsp40) member C19
RGD ID: 1560220
Description: Predicted to enable ATPase activator activity. Predicted to be involved in several processes, including protein import into mitochondrial matrix; regulation of cardiolipin metabolic process; and visual perception. Predicted to be located in matrix side of mitochondrial inner membrane. Predicted to be part of PAM complex, Tim23 associated import motor. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 5. Orthologous to human DNAJC19 (DnaJ heat shock protein family (Hsp40) member C19); PARTICIPATES IN presequence pathway of mitochondrial protein import; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DnaJ (Hsp40) homolog, subfamily C, member 19; hypothetical protein LOC502525; LOC502525; mitochondrial import inner membrane translocase subunit TIM14; RGD1560220; similar to homolog of yeast TIM14 isoform c; similar to translocase of the inner mitochondrial membrane 14 isoform a; uncharacterized protein LOC502525
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82118,851,497 - 118,875,813 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2118,869,413 - 118,873,781 (-)EnsemblGRCr8
mRatBN7.22116,923,272 - 116,945,312 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2116,923,272 - 116,945,264 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2123,512,875 - 123,534,874 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02121,625,542 - 121,647,543 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02116,253,290 - 116,275,296 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02120,503,093 - 120,531,782 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2120,504,130 - 120,531,782 (+)Ensemblrn6Rnor6.0
Rnor_5.02140,149,956 - 140,174,575 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera2111,962,564 - 111,984,600 (-)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
choline  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
fenofibrate  (ISO)
fenthion  (ISO)
folic acid  (ISO)
FR900359  (ISO)
galaxolide  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
nefazodone  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP)
thalidomide  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
triadimefon  (EXP)
trichloroethene  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Unlocking the presequence import pathway. Schulz C, etal., Trends Cell Biol. 2015 May;25(5):265-75. doi: 10.1016/j.tcb.2014.12.001. Epub 2014 Dec 23.
Additional References at PubMed
PMID:12592411   PMID:16055927   PMID:18614015   PMID:19564938   PMID:20053669  


Genomics

Comparative Map Data
Dnajc19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82118,851,497 - 118,875,813 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2118,869,413 - 118,873,781 (-)EnsemblGRCr8
mRatBN7.22116,923,272 - 116,945,312 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2116,923,272 - 116,945,264 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2123,512,875 - 123,534,874 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02121,625,542 - 121,647,543 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02116,253,290 - 116,275,296 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02120,503,093 - 120,531,782 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2120,504,130 - 120,531,782 (+)Ensemblrn6Rnor6.0
Rnor_5.02140,149,956 - 140,174,575 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera2111,962,564 - 111,984,600 (-)NCBICelera
Cytogenetic Map2q24NCBI
DNAJC19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383180,983,709 - 180,989,838 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3180,983,635 - 180,989,774 (-)Ensemblhg38GRCh38
GRCh373180,701,497 - 180,707,626 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363182,184,197 - 182,190,224 (-)NCBIBuild 36Build 36hg18NCBI36
Celera3179,133,934 - 179,140,000 (-)NCBICelera
Cytogenetic Map3q26.33NCBI
HuRef3178,105,493 - 178,111,557 (-)NCBIHuRef
CHM1_13180,664,781 - 180,670,846 (-)NCBICHM1_1
T2T-CHM13v2.03183,785,491 - 183,791,620 (-)NCBIT2T-CHM13v2.0
Dnajc19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39334,111,429 - 34,135,503 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl334,110,169 - 34,135,470 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38334,057,280 - 34,081,354 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl334,056,020 - 34,081,321 (-)Ensemblmm10GRCm38
MGSCv37333,956,680 - 33,980,248 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36334,249,307 - 34,272,875 (-)NCBIMGSCv36mm8
Celera333,953,924 - 33,977,453 (-)NCBICelera
Cytogenetic Map3A3NCBI
cM Map316.43NCBI
Dnajc19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554209,953,045 - 9,978,789 (-)Ensembl
ChiLan1.0NW_0049554209,974,466 - 9,978,789 (-)NCBIChiLan1.0ChiLan1.0
DNAJC19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22178,855,625 - 178,861,633 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13178,860,342 - 178,866,350 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03178,019,161 - 178,025,272 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13186,191,128 - 186,197,156 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3186,191,128 - 186,195,666 (-)EnsemblpanPan2panpan1.1
DNAJC19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13414,199,507 - 14,204,736 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3414,199,675 - 14,204,687 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3418,281,677 - 18,286,739 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03414,101,051 - 14,106,123 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3414,098,572 - 14,106,041 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13414,146,876 - 14,151,940 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03414,129,181 - 14,134,245 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03414,373,244 - 14,378,316 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dnajc19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602110,872,579 - 110,877,731 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365662,343,013 - 2,368,213 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365662,342,995 - 2,348,345 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJC19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13118,902,666 - 118,913,270 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113118,907,299 - 118,913,270 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213128,168,301 - 128,255,013 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJC19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1158,408,615 - 8,426,838 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl158,408,400 - 8,429,990 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606317,240,292 - 17,259,188 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnajc19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473058,730,413 - 58,755,688 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473058,746,824 - 58,755,544 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dnajc19
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13119,748,130 - 119,752,307 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dnajc19
85 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:624
Count of miRNA genes:275
Interacting mature miRNAs:336
Transcripts:ENSRNOT00000071944
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)2105628029150628029Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)282947902127947902Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)284056790132859658Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
2317886Alcrsp23Alcohol response QTL 232.40.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)295142371140142371Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
2317058Aia13Adjuvant induced arthritis QTL 132.9joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)278269809123269809Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2100807373145807373Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2106869825151869825Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)293602631145807373Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)282214549127214549Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
7488933Bp368Blood pressure QTL 3680.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2104957381149957381Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1581552Pur12Proteinuria QTL 125.190.0009urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)2114032149150226270Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)2114440891159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1354594Despr10Despair related QTL 102e-06locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2116804572161804572Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat

Markers in Region
RH130227  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22116,943,105 - 116,944,207 (-)MAPPERmRatBN7.2
mRatBN7.22183,874,347 - 183,874,544 (+)MAPPERmRatBN7.2
Rnor_6.02198,453,117 - 198,453,313NCBIRnor6.0
Rnor_6.02120,505,187 - 120,506,288NCBIRnor6.0
Rnor_5.02217,938,876 - 217,939,072UniSTSRnor5.0
Rnor_5.02140,151,029 - 140,152,130UniSTSRnor5.0
RGSC_v3.42191,118,700 - 191,118,896UniSTSRGSC3.4
Celera2176,401,946 - 176,402,142UniSTS
Celera2111,982,442 - 111,983,543UniSTS
RH 3.4 Map2683.4UniSTS
Cytogenetic Map2q25UniSTS
RH132222  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22116,932,491 - 116,932,685 (-)MAPPERmRatBN7.2
Rnor_6.02120,516,718 - 120,516,911NCBIRnor6.0
Rnor_5.02140,162,560 - 140,162,753UniSTSRnor5.0
RGSC_v3.42120,379,472 - 120,379,665UniSTSRGSC3.4
Celera2111,971,786 - 111,971,979UniSTS
RH 3.4 Map2683.6UniSTS
Cytogenetic Map2q25UniSTS
X90875  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.02140,158,874 - 140,159,032UniSTSRnor5.0
Rnor_5.02140,165,423 - 140,165,581UniSTSRnor5.0
Celera2111,975,507 - 111,975,665UniSTS
Cytogenetic Map2q25UniSTS
RH139070  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22116,924,570 - 116,924,704 (-)MAPPERmRatBN7.2
Rnor_6.02120,530,350 - 120,530,483NCBIRnor6.0
Rnor_5.02140,173,143 - 140,173,276UniSTSRnor5.0
Celera2111,963,863 - 111,963,996UniSTS
RH 3.4 Map2684.9UniSTS
Cytogenetic Map2q25UniSTS
BI274570  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22116,935,372 - 116,936,240 (-)MAPPERmRatBN7.2
Rnor_6.02120,519,947 - 120,520,151NCBIRnor6.0
Rnor_6.02120,513,163 - 120,514,030NCBIRnor6.0
Rnor_5.02140,159,005 - 140,159,872UniSTSRnor5.0
Rnor_5.02140,165,554 - 140,165,758UniSTSRnor5.0
Celera2111,974,667 - 111,975,534UniSTS
RH 3.4 Map116.7UniSTS
Cytogenetic Map2q25UniSTS
BI281166  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02120,520,007 - 120,520,204NCBIRnor6.0
Rnor_5.02140,165,614 - 140,165,811UniSTSRnor5.0
RH 3.4 Map116.7UniSTS
Cytogenetic Map2q25UniSTS
G34972  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82186,563,073 - 186,563,219 (+)Marker Load Pipeline
mRatBN7.22183,874,210 - 183,874,356 (+)MAPPERmRatBN7.2
Rnor_6.02198,452,980 - 198,453,125NCBIRnor6.0
Rnor_5.02217,938,739 - 217,938,884UniSTSRnor5.0
RGSC_v3.42191,118,563 - 191,118,708UniSTSRGSC3.4
Celera2176,401,809 - 176,401,954UniSTS
Cytogenetic Map2q25UniSTS
RH66895  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22183,874,210 - 183,874,356 (+)MAPPERmRatBN7.2
Rnor_6.02198,452,980 - 198,453,125NCBIRnor6.0
Rnor_5.02217,938,739 - 217,938,884UniSTSRnor5.0
RGSC_v3.42191,118,563 - 191,118,708UniSTSRGSC3.4
Celera2176,401,809 - 176,401,954UniSTS
Cytogenetic Map2q25UniSTS
UniSTS:479111  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02120,520,193 - 120,520,822NCBIRnor6.0
Rnor_5.02140,165,800 - 140,166,429UniSTSRnor5.0
Cytogenetic Map2q25UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000071944   ⟹   ENSRNOP00000065070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2116,923,272 - 116,945,264 (-)Ensembl
Rnor_6.0 Ensembl2120,504,130 - 120,531,782 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104976   ⟹   ENSRNOP00000089472
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2116,941,140 - 116,944,961 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108781   ⟹   ENSRNOP00000079072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2116,923,272 - 116,945,109 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109197   ⟹   ENSRNOP00000086942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2118,869,413 - 118,873,781 (-)Ensembl
mRatBN7.2 Ensembl2116,941,140 - 116,945,109 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118294   ⟹   ENSRNOP00000080178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2118,870,658 - 118,873,487 (-)Ensembl
mRatBN7.2 Ensembl2116,942,435 - 116,945,264 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118548   ⟹   ENSRNOP00000083629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2118,869,413 - 118,873,060 (-)Ensembl
mRatBN7.2 Ensembl2116,941,140 - 116,945,164 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118761   ⟹   ENSRNOP00000083714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2116,923,272 - 116,944,268 (-)Ensembl
RefSeq Acc Id: NM_001134640   ⟹   NP_001128112
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82118,851,497 - 118,873,487 (-)NCBI
mRatBN7.22116,923,272 - 116,945,264 (-)NCBI
Rnor_6.02120,504,130 - 120,531,782 (+)NCBI
Rnor_5.02140,149,956 - 140,174,575 (+)NCBI
Celera2111,962,564 - 111,984,600 (-)RGD
Sequence:
RefSeq Acc Id: XM_006232259   ⟹   XP_006232321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82118,869,322 - 118,873,547 (-)NCBI
mRatBN7.22116,941,099 - 116,945,312 (-)NCBI
Rnor_6.02120,504,119 - 120,508,303 (+)NCBI
Rnor_5.02140,149,956 - 140,174,575 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063282411   ⟹   XP_063138481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82118,869,322 - 118,875,813 (-)NCBI
RefSeq Acc Id: NP_001128112   ⟸   NM_001134640
- UniProtKB: M0R6L8 (UniProtKB/TrEMBL),   A6IHT6 (UniProtKB/TrEMBL),   A0A8I5ZMN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232321   ⟸   XM_006232259
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000065070   ⟸   ENSRNOT00000071944
Ensembl Acc Id: ENSRNOP00000083714   ⟸   ENSRNOT00000118761
Ensembl Acc Id: ENSRNOP00000083629   ⟸   ENSRNOT00000118548
Ensembl Acc Id: ENSRNOP00000079072   ⟸   ENSRNOT00000108781
Ensembl Acc Id: ENSRNOP00000086942   ⟸   ENSRNOT00000109197
Ensembl Acc Id: ENSRNOP00000080178   ⟸   ENSRNOT00000118294
Ensembl Acc Id: ENSRNOP00000089472   ⟸   ENSRNOT00000104976
RefSeq Acc Id: XP_063138481   ⟸   XM_063282411
- Peptide Label: isoform X1
Protein Domains
J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R6L8-F1-model_v2 AlphaFold M0R6L8 1-178 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691286
Promoter ID:EPDNEW_R1811
Type:initiation region
Name:Dnajc19_1
Description:DnaJ heat shock protein family member C19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02120,504,141 - 120,504,201EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560220 AgrOrtholog
BioCyc Gene G2FUF-53395 BioCyc
Ensembl Genes ENSRNOG00000049819 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000109197.2 UniProtKB/TrEMBL
  ENSRNOT00000118294.2 UniProtKB/TrEMBL
  ENSRNOT00000118548 ENTREZGENE
  ENSRNOT00000118548.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.110 UniProtKB/TrEMBL
InterPro DnaJ_dom_sf UniProtKB/TrEMBL
  DnaJ_domain UniProtKB/TrEMBL
KEGG Report rno:502525 UniProtKB/TrEMBL
NCBI Gene 502525 ENTREZGENE
PANTHER MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM14 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam DnaJ UniProtKB/TrEMBL
PhenoGen Dnajc19 PhenoGen
PROSITE DNAJ_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049819 RatGTEx
SMART DnaJ UniProtKB/TrEMBL
Superfamily-SCOP DnaJ_N UniProtKB/TrEMBL
UniProt A0A8I5ZMN9 ENTREZGENE
  A0A8I5ZP86_RAT UniProtKB/TrEMBL
  A0A8I6A0C7_RAT UniProtKB/TrEMBL
  A0A8I6A7G6 ENTREZGENE, UniProtKB/TrEMBL
  A6IHT6 ENTREZGENE, UniProtKB/TrEMBL
  A6IHT7 ENTREZGENE, UniProtKB/TrEMBL
  M0R6L8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Dnajc19  DnaJ heat shock protein family (Hsp40) member C19  Dnajc19  DnaJ (Hsp40) homolog, subfamily C, member 19  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-22 Dnajc19  DnaJ (Hsp40) homolog, subfamily C, member 19  RGD1560220  similar to homolog of yeast TIM14 isoform c  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 RGD1560220  similar to homolog of yeast TIM14 isoform c  LOC683663  similar to translocase of the inner mitochondrial membrane 14 isoform a  Data merged from RGD:1584489 1643240 APPROVED
2008-04-30 RGD1560220  similar to homolog of yeast TIM14 isoform c   RGD1560220_predicted  similar to homolog of yeast TIM14 isoform c (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 LOC683663  similar to translocase of the inner mitochondrial membrane 14 isoform a      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1560220_predicted  similar to homolog of yeast TIM14 isoform c (predicted)  LOC502525  similar to homolog of yeast TIM14 isoform c  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC502525  similar to homolog of yeast TIM14 isoform c      Symbol and Name status set to provisional 70820 PROVISIONAL