Rbfox3 (RNA binding fox-1 homolog 3) - Rat Genome Database

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Gene: Rbfox3 (RNA binding fox-1 homolog 3) Rattus norvegicus
Analyze
Symbol: Rbfox3
Name: RNA binding fox-1 homolog 3
RGD ID: 1560070
Description: Predicted to enable DNA binding activity and mRNA binding activity. Predicted to be involved in nervous system development and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in perikaryon. Predicted to be active in cytoplasm and nucleus. Biomarker of brain infarction and middle cerebral artery infarction. Orthologous to human RBFOX3 (RNA binding fox-1 homolog 3); INTERACTS WITH 1-bromopropane; 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fox-1 homolog C; hexaribonucleotide binding protein 3; Hrnbp3; hypothetical protein LOC287847; LOC287847; Neun; neuronal nuclei; RGD1560070; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog (C. elegans) 3; RNA binding protein, fox-1 homolog 3; similar to ataxin 2-binding protein 1 isoform 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810104,218,940 - 104,655,863 (-)NCBIGRCr8
mRatBN7.210103,720,355 - 104,157,277 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10103,720,636 - 104,156,935 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10108,824,453 - 108,845,549 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010108,287,495 - 108,308,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010103,643,946 - 103,665,198 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010107,517,916 - 107,850,764 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10107,516,995 - 107,539,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010107,150,696 - 107,577,314 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,492,172 - 108,635,296 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10102,283,623 - 102,304,489 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-cotinine  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-bromopropane  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3',5'-cyclic AMP  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
9-cis-retinoic acid  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
azithromycin  (ISO)
BAPTA  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
Calcitonin gene-related peptide 1  (EXP)
carbofuran  (EXP)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
Diallyl sulfide  (EXP)
diethyl hydrogen phosphate  (ISO)
diisopropyl fluorophosphate  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
genistein  (ISO)
L-ascorbic acid  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (EXP,ISO)
Licochalcone B  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
minocycline  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nicotine  (ISO)
Nonylphenol  (EXP)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paraquat  (ISO)
pexidartinib  (ISO)
phenylmercury acetate  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
SB 431542  (EXP,ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sterigmatocystin  (EXP)
testosterone  (EXP,ISO)
Theaflavin 3,3'-digallate  (ISO)
thimerosal  (ISO)
thymoquinone  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
neuronal cell body  (ISO)
nucleus  (IBA,ISO)
perikaryon  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Neuronal replacement from endogenous precursors in the adult brain after stroke. Arvidsson A, etal., Nat Med. 2002 Sep;8(9):963-70. doi: 10.1038/nm747. Epub 2002 Aug 5.
2. Intranasal Calcitonin Gene-Related Peptide Protects Against Focal Cerebral Ischemic Injury in Rats Through the Wnt/β-Catenin Pathway. Du Z, etal., Med Sci Monit. 2018 Dec 7;24:8860-8869. doi: 10.12659/MSM.913777.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1483388   PMID:15148382   PMID:15964665   PMID:16314515   PMID:17018287   PMID:17301088   PMID:17606467   PMID:19646951   PMID:19682546   PMID:20418887   PMID:20452351   PMID:20578039  
PMID:21172456   PMID:21747913   PMID:23447615   PMID:23836929   PMID:23877069   PMID:24367100   PMID:25798055   PMID:25834037   PMID:26987225   PMID:27487661   PMID:34146639  


Genomics

Comparative Map Data
Rbfox3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810104,218,940 - 104,655,863 (-)NCBIGRCr8
mRatBN7.210103,720,355 - 104,157,277 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10103,720,636 - 104,156,935 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10108,824,453 - 108,845,549 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010108,287,495 - 108,308,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010103,643,946 - 103,665,198 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010107,517,916 - 107,850,764 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10107,516,995 - 107,539,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010107,150,696 - 107,577,314 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,492,172 - 108,635,296 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10102,283,623 - 102,304,489 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
RBFOX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381779,089,345 - 79,665,571 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1779,089,345 - 79,611,051 (-)EnsemblGRCh38hg38GRCh38
GRCh371777,085,427 - 77,632,826 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361774,743,415 - 74,931,797 (-)NCBINCBI36Build 36hg18NCBI36
Celera1773,683,652 - 74,076,296 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1772,508,346 - 72,935,630 (-)NCBIHuRef
CHM1_11777,149,351 - 77,576,178 (-)NCBICHM1_1
T2T-CHM13v2.01779,984,286 - 80,563,418 (-)NCBIT2T-CHM13v2.0
Rbfox3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911118,380,586 - 118,802,423 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11118,380,588 - 118,802,423 (-)EnsemblGRCm39 Ensembl
GRCm3811118,489,760 - 118,911,597 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11118,489,762 - 118,911,597 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711118,351,074 - 118,770,886 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611118,305,850 - 118,725,662 (-)NCBIMGSCv36mm8
Celera11130,235,488 - 130,656,656 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1183.22NCBI
Rbfox3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555063,624,378 - 3,646,789 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555063,243,637 - 3,646,789 (+)NCBIChiLan1.0ChiLan1.0
RBFOX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21995,136,350 - 95,664,449 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11799,966,424 - 100,493,350 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01773,163,818 - 73,690,675 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11778,711,056 - 79,099,721 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1778,711,056 - 78,732,131 (-)Ensemblpanpan1.1panPan2
RBFOX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.192,362,354 - 2,374,492 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl92,362,231 - 2,372,739 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha92,584,621 - 3,030,199 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.092,577,342 - 3,023,588 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl92,906,484 - 3,023,598 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.192,600,496 - 3,046,030 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.092,726,153 - 3,171,835 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.092,807,110 - 3,252,747 (+)NCBIUU_Cfam_GSD_1.0
Rbfox3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056022,997,298 - 3,017,367 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365943,393,666 - 3,414,628 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365943,393,675 - 3,744,755 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBFOX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl123,116,773 - 3,138,840 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1123,116,769 - 3,138,846 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RBFOX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11671,058,257 - 71,673,053 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1671,058,131 - 71,276,475 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607742,319,760 - 42,874,640 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbfox3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248018,404,285 - 8,424,652 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248018,404,271 - 8,795,695 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbfox3
2486 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:57
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000004524
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093223816107057807Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090404397107211142Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)1096703043107057807Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087307617107211142Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090627439107211142Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1090627439107057807Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1096703043107057807Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1064890616107211142Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1090404397107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1088539139107211142Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
1576313Pia25Pristane induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096120911104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1576307Cia28Collagen induced arthritis QTL 28joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096120911104060283Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1085565469103884409Rat
631539Oia6Oil induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1097010147104670812Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087055121107211142Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091228102104060283Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat

Markers in Region
D10Rat134  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210103,784,905 - 103,785,112 (+)MAPPERmRatBN7.2
Rnor_6.010107,579,840 - 107,580,046NCBIRnor6.0
Rnor_5.010107,214,772 - 107,214,978UniSTSRnor5.0
RGSC_v3.410108,557,381 - 108,557,588RGDRGSC3.4
RGSC_v3.410108,557,382 - 108,557,588UniSTSRGSC3.4
RGSC_v3.110108,571,885 - 108,572,092RGD
Celera10102,344,864 - 102,345,070UniSTS
SHRSP x BN Map1092.75RGD
SHRSP x BN Map1092.75UniSTS
Cytogenetic Map10q32.3UniSTS
D10Arb22  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210104,060,133 - 104,060,283 (+)MAPPERmRatBN7.2
Rnor_6.010107,857,524 - 107,857,673NCBIRnor6.0
Rnor_5.010107,484,612 - 107,484,761UniSTSRnor5.0
Celera10102,615,292 - 102,615,441UniSTS
Cytogenetic Map10q32.3UniSTS
D10Wox32  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210104,060,093 - 104,060,279 (+)MAPPERmRatBN7.2
Rnor_6.010107,857,484 - 107,857,669NCBIRnor6.0
Rnor_5.010107,484,572 - 107,484,757UniSTSRnor5.0
Celera10102,615,252 - 102,615,437UniSTS
Cytogenetic Map10q32.3UniSTS
D10Got224  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210104,149,673 - 104,149,816 (+)MAPPERmRatBN7.2
Rnor_6.010107,947,311 - 107,947,453NCBIRnor6.0
Rnor_5.010107,570,952 - 107,571,094UniSTSRnor5.0
Celera10102,702,890 - 102,703,032UniSTS
Cytogenetic Map10q32.3UniSTS
AU047523  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210104,071,393 - 104,071,568 (+)MAPPERmRatBN7.2
Rnor_6.010107,868,812 - 107,868,987NCBIRnor6.0
Rnor_5.010107,495,900 - 107,496,075UniSTSRnor5.0
Celera10102,626,561 - 102,626,739UniSTS
Cytogenetic Map10q32.3UniSTS
AI228530  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210103,835,819 - 103,836,072 (+)MAPPERmRatBN7.2
mRatBN7.21825,951,336 - 25,951,586 (+)MAPPERmRatBN7.2
Rnor_6.01827,134,422 - 27,134,671NCBIRnor6.0
Rnor_6.010107,631,211 - 107,631,463NCBIRnor6.0
Rnor_5.01826,847,961 - 26,848,210UniSTSRnor5.0
Rnor_5.010107,265,698 - 107,265,950UniSTSRnor5.0
RGSC_v3.410108,608,479 - 108,608,731UniSTSRGSC3.4
RGSC_v3.41826,819,849 - 26,820,098UniSTSRGSC3.4
Celera1825,692,430 - 25,692,679UniSTS
Celera10102,395,754 - 102,396,006UniSTS
RH 3.4 Map18346.4UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
D2S147  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210103,878,082 - 103,879,235 (+)MAPPERmRatBN7.2
Rnor_6.010107,672,500 - 107,673,652NCBIRnor6.0
Rnor_5.010107,306,741 - 107,307,893UniSTSRnor5.0
RGSC_v3.410108,650,504 - 108,651,656UniSTSRGSC3.4
Celera10102,436,303 - 102,437,455UniSTS
Cytogenetic Map10q32.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 49 113 86 85 57 21 57 6 208 91 93 45 60 28

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001413230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010055159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010055160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010055161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000004524   ⟹   ENSRNOP00000004524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10103,723,278 - 104,156,935 (-)Ensembl
Rnor_6.0 Ensembl10107,518,744 - 107,539,465 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089346   ⟹   ENSRNOP00000072266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10103,721,541 - 104,156,935 (-)Ensembl
Rnor_6.0 Ensembl10107,516,995 - 107,539,658 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120132   ⟹   ENSRNOP00000091761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10103,720,636 - 104,156,935 (-)Ensembl
RefSeq Acc Id: NM_001134498   ⟹   NP_001127970
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,218,940 - 104,655,544 (-)NCBI
mRatBN7.210103,720,355 - 104,156,965 (-)NCBI
Rnor_6.010107,518,744 - 107,539,465 (-)NCBI
Rnor_5.010107,150,696 - 107,577,314 (-)NCBI
RGSC_v3.410108,492,172 - 108,635,296 (-)RGD
Celera10102,283,623 - 102,304,489 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001413230   ⟹   NP_001400159
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,218,940 - 104,655,544 (-)NCBI
mRatBN7.210103,720,355 - 104,156,965 (-)NCBI
RefSeq Acc Id: XM_039085677   ⟹   XP_038941605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,221,270 - 104,301,743 (-)NCBI
mRatBN7.210103,722,685 - 103,803,103 (-)NCBI
RefSeq Acc Id: XM_039085678   ⟹   XP_038941606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,221,270 - 104,301,743 (-)NCBI
mRatBN7.210103,722,685 - 103,803,111 (-)NCBI
RefSeq Acc Id: XM_039085679   ⟹   XP_038941607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,218,940 - 104,301,743 (-)NCBI
mRatBN7.210103,720,355 - 103,803,099 (-)NCBI
RefSeq Acc Id: XM_039085682   ⟹   XP_038941610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,221,270 - 104,301,743 (-)NCBI
mRatBN7.210103,722,685 - 103,803,101 (-)NCBI
RefSeq Acc Id: XM_039085683   ⟹   XP_038941611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,221,270 - 104,301,743 (-)NCBI
mRatBN7.210103,722,685 - 103,803,110 (-)NCBI
RefSeq Acc Id: XM_039085684   ⟹   XP_038941612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,218,940 - 104,301,743 (-)NCBI
mRatBN7.210103,720,355 - 103,803,096 (-)NCBI
RefSeq Acc Id: XM_063268783   ⟹   XP_063124853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,225,582 - 104,301,743 (-)NCBI
RefSeq Acc Id: XM_063268784   ⟹   XP_063124854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,225,582 - 104,301,743 (-)NCBI
RefSeq Acc Id: XM_063268785   ⟹   XP_063124855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,225,582 - 104,655,858 (-)NCBI
RefSeq Acc Id: XM_063268786   ⟹   XP_063124856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,225,582 - 104,655,863 (-)NCBI
RefSeq Acc Id: XM_063268787   ⟹   XP_063124857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,225,582 - 104,655,858 (-)NCBI
RefSeq Acc Id: XR_010055159
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,243,018 - 104,633,996 (-)NCBI
RefSeq Acc Id: XR_010055160
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,383,044 - 104,633,996 (-)NCBI
RefSeq Acc Id: XR_010055161
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,539,090 - 104,633,996 (-)NCBI
RefSeq Acc Id: NP_001127970   ⟸   NM_001134498
- Peptide Label: isoform 2
- UniProtKB: D4A2H6 (UniProtKB/TrEMBL),   A6HL63 (UniProtKB/TrEMBL),   A6HL62 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004524   ⟸   ENSRNOT00000004524
Ensembl Acc Id: ENSRNOP00000072266   ⟸   ENSRNOT00000089346
RefSeq Acc Id: XP_038941607   ⟸   XM_039085679
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038941612   ⟸   XM_039085684
- Peptide Label: isoform X9
- UniProtKB: A6HL62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941606   ⟸   XM_039085678
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038941611   ⟸   XM_039085683
- Peptide Label: isoform X8
- UniProtKB: A6HL62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941605   ⟸   XM_039085677
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941610   ⟸   XM_039085682
- Peptide Label: isoform X7
- UniProtKB: A6HL62 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000091761   ⟸   ENSRNOT00000120132
RefSeq Acc Id: NP_001400159   ⟸   NM_001413230
- Peptide Label: isoform 1
RefSeq Acc Id: XP_063124856   ⟸   XM_063268786
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063124857   ⟸   XM_063268787
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063124855   ⟸   XM_063268785
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063124854   ⟸   XM_063268784
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063124853   ⟸   XM_063268783
- Peptide Label: isoform X1
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A2H6-F1-model_v2 AlphaFold D4A2H6 1-375 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560070 AgrOrtholog
BioCyc Gene G2FUF-22511 BioCyc
Ensembl Genes ENSRNOG00000003386 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004524.6 UniProtKB/TrEMBL
  ENSRNOT00000089346.2 UniProtKB/TrEMBL
  ENSRNOT00000120132.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Fox-1_C_dom UniProtKB/TrEMBL
  FOX1_RRM UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RBFOX1-like UniProtKB/TrEMBL
  RNA-bd_9/Ataxin-2-bd UniProtKB/TrEMBL
  RRM_RNP1 UniProtKB/TrEMBL
KEGG Report rno:287847 UniProtKB/TrEMBL
NCBI Gene 287847 ENTREZGENE
PANTHER ATAXIN 2-BINDING PROTEIN 1-RELATED UniProtKB/TrEMBL
  RNA BINDING PROTEIN FOX-1 HOMOLOG 3 UniProtKB/TrEMBL
Pfam Fox-1_C UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PhenoGen Rbfox3 PhenoGen
PIRSF Ataxin_2_bd_A2BP UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003386 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A0G2K2J4_RAT UniProtKB/TrEMBL
  A0A8I6AGR7_RAT UniProtKB/TrEMBL
  A6HL62 ENTREZGENE, UniProtKB/TrEMBL
  A6HL63 ENTREZGENE, UniProtKB/TrEMBL
  D4A2H6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-28 Rbfox3  RNA binding fox-1 homolog 3  Rbfox3  RNA binding protein, fox-1 homolog 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-27 Rbfox3  RNA binding protein, fox-1 homolog 3  Rbfox3  RNA binding protein, fox-1 homolog (C. elegans) 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-02 Rbfox3  RNA binding protein, fox-1 homolog (C. elegans) 3  Hrnbp3  hexaribonucleotide binding protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Hrnbp3  hexaribonucleotide binding protein 3  RGD1560070  similar to ataxin 2-binding protein 1 isoform 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1560070  similar to ataxin 2-binding protein 1 isoform 2   RGD1560070_predicted  similar to ataxin 2-binding protein 1 isoform 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560070_predicted  similar to ataxin 2-binding protein 1 isoform 2 (predicted)  LOC287847  similar to ataxin 2-binding protein 1 isoform 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC287847  similar to ataxin 2-binding protein 1 isoform 2      Symbol and Name status set to provisional 70820 PROVISIONAL