Rpl27l4 (ribosomal protein L27 like 4) - Rat Genome Database

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Gene: Rpl27l4 (ribosomal protein L27 like 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rpl27l4 (Ensembl: AABR07018976.1)
Name: ribosomal protein L27 like 4
RGD ID: 1560069
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome and rough endoplasmic reticulum. Predicted to be part of ribonucleoprotein complex; INTERACTS WITH bisphenol A.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: 60S ribosomal protein L27-like; LOC364450; RGD1560069; similar to ribosomal protein L27
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81581,418,120 - 81,422,824 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21575,010,185 - 75,011,443 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1575,010,179 - 75,010,634 (-)EnsemblmRatBN7.2
Rnor_6.01582,578,006 - 82,581,931 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01586,111,632 - 86,115,542 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41581,680,519 - 81,684,431 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1574,261,422 - 74,265,349 (-)NCBICelera
Cytogenetic Map15q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rpl27l4
6 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:63
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000057891
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)155559608991365858Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
70182BpQTLcluster12Blood pressure QTL cluster 123.53arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)157369065795018120Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)155559608995018120Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157369051895018228Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat


Expression

RNA-SEQ Expression

ectoderm
mesenchyme
nervous system
renal system
sensory system
visual system
1 5 1 5 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000057891   ⟹   ENSRNOP00000054699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1718,170,536 - 18,170,999 (-)Ensembl
mRatBN7.2 Ensembl1575,010,179 - 75,010,634 (-)Ensembl
Rnor_6.0 Ensembl1582,581,506 - 82,581,916 (-)Ensembl
RefSeq Acc Id: XM_039094082   ⟹   XP_038950010
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21575,010,185 - 75,011,443 (-)NCBI
Protein Sequences
Ensembl Protein ENSRNOP00000054699.2
RefSeq Acc Id: XP_038950010   ⟸   XM_039094082
Ensembl Acc Id: ENSRNOP00000054699   ⟸   ENSRNOT00000057891

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A7W3-F1-model_v2 AlphaFold D4A7W3 1-137 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560069 AgrOrtholog
BioCyc Gene G2FUF-12795 BioCyc
Ensembl Genes ENSRNOG00000038041 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057891.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.770 UniProtKB/TrEMBL
InterPro KOW_RPL27 UniProtKB/TrEMBL
  L27e_sf UniProtKB/TrEMBL
  Ribosomal_L27e UniProtKB/TrEMBL
  Translation_prot_SH3-like_sf UniProtKB/TrEMBL
NCBI Gene 364450 ENTREZGENE
PANTHER PTHR10497 UniProtKB/TrEMBL
Pfam Ribosomal_L27e UniProtKB/TrEMBL
PhenoGen Rpl27l4 PhenoGen
RatGTEx ENSRNOG00000038041 RatGTEx
Superfamily-SCOP SSF50104 UniProtKB/TrEMBL
UniProt D4A7W3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rpl27l4  ribosomal protein L27 like 4  RGD1560069  similar to ribosomal protein L27  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1560069  similar to ribosomal protein L27   RGD1560069_predicted  similar to ribosomal protein L27 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560069_predicted  similar to ribosomal protein L27 (predicted)  LOC364450  similar to ribosomal protein L27  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC364450  similar to ribosomal protein L27      Symbol and Name status set to provisional 70820 PROVISIONAL