Atp5hl1 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d-like 1) - Rat Genome Database

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Gene: Atp5hl1 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d-like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Atp5hl1 (Ensembl: AABR07025819.1)
Name: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d-like 1
RGD ID: 1559626
Description: Predicted to enable proton transmembrane transporter activity. Predicted to be involved in proton motive force-driven ATP synthesis and proton transmembrane transport. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH Cuprizon.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: ATP synthase subunit d, mitochondrial-like; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d-like 1; LOC306478; RGD1559626; similar to ATP synthase D chain, mitochondrial
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Functional Gene: Atp5pd  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81655,360,802 - 55,361,401 (+)NCBIGRCr8
mRatBN7.21648,628,349 - 48,628,948 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1648,628,407 - 48,628,892 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01651,816,495 - 51,817,031 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01651,540,728 - 51,541,249 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41651,796,082 - 51,796,567 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1646,605,449 - 46,605,985 (+)NCBICelera
Cytogenetic Map16q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Cuprizon  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Variants

.
Variants in Atp5hl1
2 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)162515279370152793Rat
1298529Arunc1Aerobic running capacity QTL 14exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)163195152060148445Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
631833Sach2Saccharin preference QTL 240.01consumption behavior trait (VT:0002069)calculated saccharin drink intake rate (CMO:0001613)164302484250166018Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000059185   ⟹   ENSRNOP00000082121
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1648,628,407 - 48,628,892 (+)Ensembl
Rnor_6.0 Ensembl1651,816,533 - 51,817,018 (+)Ensembl
RefSeq Acc Id: XM_039094929   ⟹   XP_038950857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21648,628,363 - 48,628,892 (+)NCBI
Protein Sequences
Ensembl Protein ENSRNOP00000082121.1
RefSeq Acc Id: XP_038950857   ⟸   XM_039094929
RefSeq Acc Id: ENSRNOP00000082121   ⟸   ENSRNOT00000059185

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-11294 BioCyc
Ensembl Genes ENSRNOG00000038744 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000059185.4 UniProtKB/TrEMBL
Gene3D-CATH 6.10.280.70 UniProtKB/TrEMBL
InterPro ATP_synth_F0_dsu_mt UniProtKB/TrEMBL
  ATP_synth_F0_dsu_sf_mt UniProtKB/TrEMBL
NCBI Gene 306478 ENTREZGENE
PANTHER ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR12700 UniProtKB/TrEMBL
Pfam Mt_ATP-synt_D UniProtKB/TrEMBL
PhenoGen Atp5hl1 PhenoGen
PIRSF ATPase_F0_D_mt UniProtKB/TrEMBL
RatGTEx ENSRNOG00000038744 RatGTEx
Superfamily-SCOP SSF161065 UniProtKB/TrEMBL
UniProt A0A8I5ZWF8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-12-01 Atp5hl1  ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d-like 1  Atp5hl1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Atp5hl1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d-like 1  RGD1559626  similar to ATP synthase D chain, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1559626  similar to ATP synthase D chain, mitochondrial   RGD1559626_predicted  similar to ATP synthase D chain, mitochondrial (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559626_predicted  similar to ATP synthase D chain, mitochondrial (predicted)  LOC306478  similar to ATP synthase D chain, mitochondrial  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC306478  similar to ATP synthase D chain, mitochondrial      Symbol and Name status set to provisional 70820 PROVISIONAL