Sik2 (salt inducible kinase 2) - Rat Genome Database

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Gene: Sik2 (salt inducible kinase 2) Mus musculus
Analyze
Symbol: Sik2
Name: salt inducible kinase 2
RGD ID: 1558433
MGI Page MGI
Description: Enables ion binding activity and protein kinase activity. Involved in several processes, including negative regulation of lipid biosynthetic process; regulation of insulin receptor signaling pathway; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within insulin receptor signaling pathway. Located in cytoplasm and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and heart. Orthologous to human SIK2 (salt inducible kinase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G630080D20Rik; salt induceable kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; serine/threonine-protein kinase SIK2; serine/threonine-protein kinase SNF1-like kinase 2; SIK-2; Snf1; SNF1-like kinase 2; Snf1lk2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39950,800,944 - 50,920,432 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl950,804,101 - 50,920,373 (-)EnsemblGRCm39 Ensembl
GRCm38950,889,644 - 51,009,132 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl950,892,801 - 51,009,073 (-)EnsemblGRCm38mm10GRCm38
MGSCv37950,700,906 - 50,817,178 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36950,645,031 - 50,761,303 (-)NCBIMGSCv36mm8
Celera948,179,153 - 48,295,530 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map927.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12624099   PMID:14610273   PMID:16141072   PMID:16141073   PMID:16817901   PMID:18239551   PMID:19351809   PMID:20819186  
PMID:20833366   PMID:21084751   PMID:21220102   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23033494   PMID:23393134   PMID:24561619   PMID:24752134   PMID:24898145   PMID:25088745  
PMID:25351958   PMID:25472719   PMID:25619259   PMID:25918234   PMID:27759007   PMID:27920213   PMID:28566287   PMID:29018127   PMID:29194435   PMID:29941929   PMID:30030465   PMID:30208308  
PMID:30503507   PMID:30528240   PMID:31409767   PMID:31430259   PMID:31636950   PMID:32325033   PMID:32343771   PMID:32457359   PMID:32554809   PMID:33600797   PMID:33688765   PMID:34160349  
PMID:34321999   PMID:34732767   PMID:36075517   PMID:36309093   PMID:36862513  


Genomics

Comparative Map Data
Sik2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39950,800,944 - 50,920,432 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl950,804,101 - 50,920,373 (-)EnsemblGRCm39 Ensembl
GRCm38950,889,644 - 51,009,132 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl950,892,801 - 51,009,073 (-)EnsemblGRCm38mm10GRCm38
MGSCv37950,700,906 - 50,817,178 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36950,645,031 - 50,761,303 (-)NCBIMGSCv36mm8
Celera948,179,153 - 48,295,530 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map927.75NCBI
SIK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811111,602,449 - 111,730,855 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11111,602,449 - 111,730,855 (+)EnsemblGRCh38hg38GRCh38
GRCh3711111,473,173 - 111,601,579 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611110,978,380 - 111,102,845 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411110,978,379 - 111,102,840NCBI
Celera11108,626,358 - 108,750,800 (+)NCBICelera
Cytogenetic Map11q23.1NCBI
HuRef11107,397,365 - 107,521,692 (+)NCBIHuRef
CHM1_111111,356,226 - 111,480,689 (+)NCBICHM1_1
T2T-CHM13v2.011111,612,584 - 111,741,007 (+)NCBIT2T-CHM13v2.0
Sik2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8860,121,913 - 60,221,707 (-)NCBIGRCr8
mRatBN7.2851,225,543 - 51,325,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl851,225,543 - 51,325,415 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0855,309,005 - 55,408,608 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl855,308,757 - 55,408,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0853,905,730 - 54,005,295 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4854,240,307 - 54,337,976 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera850,772,712 - 50,871,786 (-)NCBICelera
Cytogenetic Map8q23NCBI
Sik2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541213,342,032 - 13,457,563 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541213,342,032 - 13,458,076 (+)NCBIChiLan1.0ChiLan1.0
SIK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29112,348,699 - 112,477,488 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111113,440,776 - 113,571,851 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011106,484,913 - 106,613,711 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111110,329,237 - 110,453,543 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11110,329,237 - 110,453,543 (+)Ensemblpanpan1.1panPan2
SIK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1521,354,127 - 21,479,891 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl521,358,902 - 21,479,841 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha521,276,144 - 21,401,711 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0521,382,313 - 21,503,342 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1521,438,206 - 21,563,749 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0521,338,626 - 21,464,410 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0521,387,568 - 21,513,180 (-)NCBIUU_Cfam_GSD_1.0
Sik2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494793,894,634 - 94,013,880 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366122,691,524 - 2,810,981 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366122,691,729 - 2,810,975 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl939,368,599 - 39,483,515 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1939,368,555 - 39,483,519 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2944,262,713 - 44,269,792 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SIK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11102,944,171 - 103,070,973 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1102,944,281 - 103,068,823 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604322,907,785 - 23,034,098 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sik2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247846,745,595 - 6,895,747 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247846,728,504 - 6,900,557 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sik2
3400 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2293
Count of miRNA genes:651
Interacting mature miRNAs:820
Transcripts:ENSMUST00000041375, ENSMUST00000068484, ENSMUST00000176327, ENSMUST00000176491, ENSMUST00000176663, ENSMUST00000176824, ENSMUST00000177203, ENSMUST00000177346
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1558993Tdmq1_mtype 2 diabetes modifying QTL 1 (mouse)Not determined94041959451808670Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4659767165831177Mouse
4141754Fecq4_mfecundity QTL 4 (mouse)Not determined94754302457805204Mouse
13515057Adip20b_madiposity 20b (mouse)94870090853791702Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse
1301051Eae9_msusceptibility to experimental allergic encephalomyelitis 9 (mouse)Not determined94942029863239852Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94942029867151448Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
11080993Tglq7_mtriglyceride level QTL 7 (mouse)95011130051511300Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse

Markers in Region
D9Mit193  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38950,897,870 - 50,897,992UniSTSGRCm38
MGSCv37950,705,975 - 50,706,097UniSTSGRCm37
Celera948,184,222 - 48,184,336UniSTS
Cytogenetic Map9A5.3UniSTS
cM Map929.0UniSTS
Whitehead Genetic924.0UniSTS
Whitehead_YAC9 UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000041375   ⟹   ENSMUSP00000038761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl950,804,101 - 50,920,373 (-)Ensembl
GRCm38.p6 Ensembl950,892,801 - 51,009,073 (-)Ensembl
RefSeq Acc Id: ENSMUST00000068484
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl950,839,564 - 50,920,326 (-)Ensembl
GRCm38.p6 Ensembl950,928,264 - 51,009,026 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176327
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl950,906,884 - 50,920,311 (-)Ensembl
GRCm38.p6 Ensembl950,995,584 - 51,009,011 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176491   ⟹   ENSMUSP00000134954
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl950,804,101 - 50,920,273 (-)Ensembl
GRCm38.p6 Ensembl950,892,801 - 51,008,973 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176663   ⟹   ENSMUSP00000135376
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl950,804,101 - 50,920,236 (-)Ensembl
GRCm38.p6 Ensembl950,892,801 - 51,008,936 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176824   ⟹   ENSMUSP00000134936
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl950,804,101 - 50,920,236 (-)Ensembl
GRCm38.p6 Ensembl950,892,801 - 51,008,936 (-)Ensembl
RefSeq Acc Id: ENSMUST00000177203
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl950,841,862 - 50,920,284 (-)Ensembl
GRCm38.p6 Ensembl950,930,562 - 51,008,984 (-)Ensembl
RefSeq Acc Id: ENSMUST00000177346
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl950,845,136 - 50,920,300 (-)Ensembl
GRCm38.p6 Ensembl950,933,836 - 51,009,000 (-)Ensembl
RefSeq Acc Id: NM_001405014   ⟹   NP_001391943
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,804,101 - 50,920,357 (-)NCBI
RefSeq Acc Id: NM_001405015   ⟹   NP_001391944
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,804,101 - 50,920,357 (-)NCBI
RefSeq Acc Id: NM_178710   ⟹   NP_848825
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,804,101 - 50,920,357 (-)NCBI
GRCm38950,892,801 - 51,009,073 (-)NCBI
MGSCv37950,700,906 - 50,817,178 (-)RGD
Celera948,179,153 - 48,295,530 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006510267   ⟹   XP_006510330
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,800,944 - 50,920,432 (-)NCBI
GRCm38950,889,644 - 51,009,132 (-)NCBI
Sequence:
RefSeq Acc Id: XR_379116
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39950,800,944 - 50,920,432 (-)NCBI
GRCm38950,889,644 - 51,009,132 (-)NCBI
Sequence:
RefSeq Acc Id: NP_848825   ⟸   NM_178710
- Peptide Label: isoform 1
- UniProtKB: Q8CFH6 (UniProtKB/Swiss-Prot),   F8VPT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006510330   ⟸   XM_006510267
- Peptide Label: isoform X2
- UniProtKB: Q8CFH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000038761   ⟸   ENSMUST00000041375
RefSeq Acc Id: ENSMUSP00000134936   ⟸   ENSMUST00000176824
RefSeq Acc Id: ENSMUSP00000134954   ⟸   ENSMUST00000176491
RefSeq Acc Id: ENSMUSP00000135376   ⟸   ENSMUST00000176663
RefSeq Acc Id: NP_001391944   ⟸   NM_001405015
- Peptide Label: isoform 3
- UniProtKB: Q8CFH6 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001391943   ⟸   NM_001405014
- Peptide Label: isoform 2
- UniProtKB: Q8CFH6 (UniProtKB/Swiss-Prot),   H3BKG1 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase   UBA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CFH6-F1-model_v2 AlphaFold Q8CFH6 1-931 view protein structure

Promoters
RGD ID:6848499
Promoter ID:MM_ACW:50521
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_4Hour
Transcripts:SNF1LK2.GSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36950,693,724 - 50,694,224 (-)MPROMDB
RGD ID:6845181
Promoter ID:MM_KWN:57319
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000068484,   NM_178710,   UC009PKZ.1,   UC009PLA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36950,816,746 - 50,817,246 (-)MPROMDB
RGD ID:8669582
Promoter ID:EPDNEW_M12821
Type:initiation region
Name:Sik2_1
Description:Mus musculus salt inducible kinase 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38951,008,980 - 51,009,040EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2445031 AgrOrtholog
Ensembl Genes ENSMUSG00000037112 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000041375 ENTREZGENE
  ENSMUST00000041375.11 UniProtKB/TrEMBL
  ENSMUST00000176491.8 UniProtKB/TrEMBL
  ENSMUST00000176663 ENTREZGENE
  ENSMUST00000176663.8 UniProtKB/TrEMBL
  ENSMUST00000176824.8 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_SIK1/2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:235344 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2445031 ENTREZGENE
NCBI Gene 235344 ENTREZGENE
PANTHER MAP/MICROTUBULE AFFINITY-REGULATING KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sik2 PhenoGen
PIRSF Ser/Thr_PK_SNF1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F8VPT7 ENTREZGENE, UniProtKB/TrEMBL
  H3BJC9_MOUSE UniProtKB/TrEMBL
  H3BKG1 ENTREZGENE, UniProtKB/TrEMBL
  Q8BLX0_MOUSE UniProtKB/TrEMBL
  Q8C1B3_MOUSE UniProtKB/TrEMBL
  Q8CFH6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Sik2  salt inducible kinase 2  Snf1lk2  SNF1-like kinase 2  Symbol and/or name change 5135510 APPROVED