Pkd2 (polycystin 2, transient receptor potential cation channel) - Rat Genome Database

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Gene: Pkd2 (polycystin 2, transient receptor potential cation channel) Mus musculus
Analyze
Symbol: Pkd2
Name: polycystin 2, transient receptor potential cation channel
RGD ID: 1558338
MGI Page MGI
Description: Enables several functions, including ATPase binding activity; identical protein binding activity; and monoatomic cation channel activity. Involved in several processes, including detection of nodal flow; metal ion transport; and positive regulation of biosynthetic process. Acts upstream of or within several processes, including intracellular calcium ion homeostasis; liver development; and negative regulation of ryanodine-sensitive calcium-release channel activity. Located in several cellular components, including basal cortex; ciliary membrane; and microtubule cytoskeleton. Part of polycystin complex. Colocalizes with cell-cell junction. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Used to study autosomal dominant polycystic kidney disease and polycystic kidney disease 2. Human ortholog(s) of this gene implicated in autosomal dominant polycystic kidney disease; intracranial aneurysm; polycystic kidney disease; polycystic kidney disease 2; and retinal degeneration. Orthologous to human PKD2 (polycystin 2, transient receptor potential cation channel).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C030034P18Rik; PC; PC2; polycystic kidney disease 2; polycystic kidney disease 2 protein homolog; polycystin 2; polycystin-2; TR; transient receptor potential cation channel subfamily P member 2; TRPP2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395104,599,379 - 104,653,685 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5104,607,316 - 104,653,685 (+)EnsemblGRCm39 Ensembl
GRCm385104,453,982 - 104,505,819 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5104,459,450 - 104,505,819 (+)EnsemblGRCm38mm10GRCm38
MGSCv375104,888,476 - 104,934,838 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365104,699,856 - 104,746,118 (+)NCBIMGSCv36mm8
Celera5101,769,092 - 101,817,838 (+)NCBICelera
Cytogenetic Map5E5NCBI
cM Map550.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aorta development  (IEA)
branching involved in ureteric bud morphogenesis  (IEA)
calcium ion transmembrane transport  (IMP,ISO)
calcium ion transport  (IDA,IMP,ISO)
calcium-mediated signaling  (IEA)
cell surface receptor signaling pathway  (ISO,ISS)
cell surface receptor signaling pathway via JAK-STAT  (EXP,IDA)
cellular response to calcium ion  (IMP)
cellular response to cAMP  (IEA,ISO)
cellular response to fluid shear stress  (IMP,ISO)
cellular response to hydrostatic pressure  (IEA,ISO)
cellular response to osmotic stress  (IEA,ISO)
cilium organization  (ISO)
detection of mechanical stimulus  (IBA,IMP)
detection of nodal flow  (IMP)
determination of left/right symmetry  (IMP)
determination of liver left/right asymmetry  (IEA,ISO)
embryonic placenta development  (IMP)
establishment of localization in cell  (IMP)
heart development  (IMP,ISO)
heart looping  (IEA,ISO)
inorganic cation transmembrane transport  (ISO)
intracellular calcium ion homeostasis  (IMP)
kidney development  (IGI,IMP)
liver development  (IGI,ISO)
mesonephric duct development  (IEA)
mesonephric tubule development  (ISO)
metanephric ascending thin limb development  (IEA)
metanephric cortex development  (IEA)
metanephric cortical collecting duct development  (IEA)
metanephric distal tubule development  (IEA)
metanephric mesenchyme development  (IEA)
metanephric part of ureteric bud development  (IEA)
metanephric S-shaped body morphogenesis  (IEA)
metanephric smooth muscle tissue development  (IEA)
negative regulation of G1/S transition of mitotic cell cycle  (IEA,ISO)
negative regulation of ryanodine-sensitive calcium-release channel activity  (IDA)
neural tube development  (IEA)
placenta blood vessel development  (IMP)
positive regulation of cytosolic calcium ion concentration  (IEA,ISO)
positive regulation of gene expression  (IMP)
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity  (ISO)
positive regulation of nitric oxide biosynthetic process  (IMP,ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
potassium ion transmembrane transport  (IBA,IMP,ISO)
potassium ion transport  (IDA)
protein heterotetramerization  (ISO,ISS)
protein homotetramerization  (IEA,ISO)
protein tetramerization  (ISO,ISS)
regulation of calcium ion import  (IEA,ISO)
regulation of cell cycle  (IDA)
regulation of cell population proliferation  (IEA,ISO)
release of sequestered calcium ion into cytosol  (IBA,IMP,ISO)
renal artery morphogenesis  (IEA)
renal tubule morphogenesis  (IMP)
sodium ion transmembrane transport  (IEA,ISO)
sodium ion transport  (IDA)
spinal cord development  (IEA)
Wnt signaling pathway  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal amniotic fluid composition  (IAGP)
abnormal cholangiocyte morphology  (IAGP)
abnormal cholangiocyte primary cilium morphology  (IAGP)
abnormal direction of embryo turning  (IAGP)
abnormal heart development  (IAGP)
abnormal heart looping  (IAGP)
abnormal hepatic vein morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal left-right axis patterning  (IAGP)
abnormal liver development  (IAGP)
abnormal liver morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal mitotic spindle morphology  (IAGP)
abnormal pancreas morphology  (IAGP)
abnormal papillary duct morphology  (IAGP)
abnormal placenta vasculature  (IAGP)
abnormal placental labyrinth vasculature morphology  (IAGP)
abnormal primitive node morphology  (IAGP)
abnormal stomach position or orientation  (IAGP)
absent spleen  (IAGP)
atrial septal defect  (IAGP)
atrioventricular septal defect  (IAGP)
bile duct proliferation  (IAGP)
decreased circulating creatinine level  (IAGP)
decreased kidney cell proliferation  (IAGP)
dextrocardia  (IAGP)
dilated bile duct  (IAGP)
dilated kidney collecting duct  (IAGP)
dilated pancreatic duct  (IAGP)
dilated proximal convoluted tubule  (IAGP)
dilated renal tubule  (IAGP)
distended abdomen  (IEA)
edema  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enlarged kidney  (IAGP)
enlarged liver  (IAGP)
hemorrhage  (IAGP)
hydrops fetalis  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased cholangiocyte apoptosis  (IAGP)
increased circulating creatinine level  (IAGP)
increased glomerular capsule space  (IAGP)
increased kidney apoptosis  (IAGP)
increased kidney cell proliferation  (IAGP)
increased kidney weight  (IAGP)
increased liver weight  (IAGP)
kidney cortex cyst  (IAGP)
kidney cyst  (IAGP)
kidney failure  (IAGP)
kidney medulla cyst  (IAGP)
left pulmonary isomerism  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
liver cyst  (IAGP)
liver fibrosis  (IAGP)
mesocardia  (IAGP)
neonatal lethality  (IAGP)
no abnormal phenotype detected  (IAGP)
pancreas cyst  (IAGP)
pericardial effusion  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
polycystic kidney  (IAGP)
polyhydramnios  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
right pulmonary isomerism  (IAGP)
right-sided stomach  (IAGP)
situs ambiguus  (IAGP)
situs inversus  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A truncated polycystin-2 protein causes polycystic kidney disease and retinal degeneration in transgenic rats. Gallagher AR, etal., J Am Soc Nephrol. 2006 Oct;17(10):2719-30. doi: 10.1681/ASN.2005090979. Epub 2006 Aug 30.
2. Novel PKD1 and PKD2 mutations in autosomal dominant polycystic kidney disease (ADPKD). Hoefele J, etal., Nephrol Dial Transplant. 2011 Jul;26(7):2181-8. Epub 2010 Nov 29.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Altered expression pattern of polycystin-2 in acute and chronic renal tubular diseases. Obermuller N, etal., J Am Soc Nephrol. 2002 Jul;13(7):1855-64.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Clinical utility of PKD2 mutation testing in a polycystic kidney disease cohort attending a specialist nephrology out-patient clinic. Robinson C, etal., BMC Nephrol. 2012 Aug 3;13:79. doi: 10.1186/1471-2369-13-79.
12. Association of mutation position in polycystic kidney disease 1 (PKD1) gene and development of a vascular phenotype. Rossetti S, etal., Lancet. 2003 Jun 28;361(9376):2196-201.
13. Polycystin-2 expression is increased following experimental ischaemic renal injury. Zhao Y, etal., Nephrol Dial Transplant. 2002 Dec;17(12):2138-44.
Additional References at PubMed
PMID:8650545   PMID:9263671   PMID:9339380   PMID:9568711   PMID:9716661   PMID:10193792   PMID:10349636   PMID:10409293   PMID:10547347   PMID:10615132   PMID:10655152   PMID:10770959  
PMID:10781953   PMID:10873385   PMID:10913159   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11593033   PMID:11854751   PMID:11901144   PMID:12007403   PMID:12062060   PMID:12062067  
PMID:12140187   PMID:12239239   PMID:12388382   PMID:12477932   PMID:12514735   PMID:12520002   PMID:12640140   PMID:12840011   PMID:12851251   PMID:12859898   PMID:12874107   PMID:12946628  
PMID:14600027   PMID:14742446   PMID:15123714   PMID:15226261   PMID:15337773   PMID:15607428   PMID:15782199   PMID:15790956   PMID:15843396   PMID:15858826   PMID:16141072   PMID:16141073  
PMID:16192288   PMID:16291790   PMID:16301212   PMID:16316413   PMID:16319116   PMID:16460286   PMID:16472605   PMID:16602821   PMID:16720597   PMID:16775004   PMID:16805797   PMID:16950792  
PMID:17182135   PMID:17202419   PMID:17204494   PMID:17208416   PMID:17251353   PMID:17283055   PMID:17404231   PMID:17475663   PMID:17575307   PMID:17636028   PMID:18048422   PMID:18172001  
PMID:18178578   PMID:18199703   PMID:18235088   PMID:18235101   PMID:18263604   PMID:18356167   PMID:18552856   PMID:18725310   PMID:18729223   PMID:18754774   PMID:18782757   PMID:18799693  
PMID:18836075   PMID:18973680   PMID:19098310   PMID:19158352   PMID:19235720   PMID:19265036   PMID:19322198   PMID:19688268   PMID:19729489   PMID:19766642   PMID:19834762   PMID:19879844  
PMID:19924104   PMID:19939939   PMID:19959710   PMID:20093497   PMID:20095091   PMID:20181743   PMID:20215348   PMID:20375013   PMID:20388629   PMID:20408813   PMID:20487527   PMID:20634433  
PMID:20686448   PMID:20843830   PMID:20862291   PMID:21109758   PMID:21270095   PMID:21298052   PMID:21307093   PMID:21389971   PMID:21474562   PMID:21508103   PMID:21670265   PMID:21685914  
PMID:21725307   PMID:21873635   PMID:22031837   PMID:22155264   PMID:22192412   PMID:22258321   PMID:22311617   PMID:22675211   PMID:22737085   PMID:22794259   PMID:22811488   PMID:22832196  
PMID:22983710   PMID:23103499   PMID:23252604   PMID:23274954   PMID:23357539   PMID:23390129   PMID:23390131   PMID:23892607   PMID:23977387   PMID:24157948   PMID:24193408   PMID:24211536  
PMID:24235270   PMID:24268313   PMID:24459142   PMID:24515114   PMID:24594709   PMID:24767998   PMID:24847003   PMID:24951251   PMID:25143454   PMID:25228769   PMID:25266776   PMID:25365220  
PMID:25368166   PMID:25405894   PMID:25464512   PMID:25503729   PMID:25537744   PMID:25574838   PMID:25587122   PMID:25715394   PMID:25715395   PMID:25934702   PMID:26245976   PMID:26254047  
PMID:26435415   PMID:26538633   PMID:26677864   PMID:26769565   PMID:26771085   PMID:26792178   PMID:27081851   PMID:27213553   PMID:27272319   PMID:27760766   PMID:27826057   PMID:28154160  
PMID:28205547   PMID:28244683   PMID:28729032   PMID:28750036   PMID:28762163   PMID:28800037   PMID:28826940   PMID:29042084   PMID:29056552   PMID:29074972   PMID:29097366   PMID:29401581  
PMID:29443690   PMID:29475398   PMID:29518398   PMID:29650695   PMID:29716997   PMID:30378388   PMID:30511640   PMID:30550785   PMID:30799239   PMID:30799240   PMID:30883612   PMID:31048699  
PMID:31064883   PMID:31313950   PMID:31411061   PMID:31492868   PMID:31541223   PMID:31601454   PMID:31822608   PMID:31887266   PMID:31941974   PMID:32182218   PMID:32325033   PMID:32364494  
PMID:32554809   PMID:32651191   PMID:32867798   PMID:32946258   PMID:33046531   PMID:33639177   PMID:33737325   PMID:34199520   PMID:34210974   PMID:34345895   PMID:35229718   PMID:35675637  
PMID:35831318   PMID:35835458   PMID:35961787   PMID:35965273   PMID:37196079   PMID:37198573   PMID:37332102   PMID:37519231   PMID:37720991   PMID:37953472   PMID:38653356   PMID:38782303  


Genomics

Comparative Map Data
Pkd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395104,599,379 - 104,653,685 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5104,607,316 - 104,653,685 (+)EnsemblGRCm39 Ensembl
GRCm385104,453,982 - 104,505,819 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5104,459,450 - 104,505,819 (+)EnsemblGRCm38mm10GRCm38
MGSCv375104,888,476 - 104,934,838 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365104,699,856 - 104,746,118 (+)NCBIMGSCv36mm8
Celera5101,769,092 - 101,817,838 (+)NCBICelera
Cytogenetic Map5E5NCBI
cM Map550.68NCBI
PKD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38488,007,635 - 88,077,777 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl488,007,635 - 88,077,777 (+)EnsemblGRCh38hg38GRCh38
GRCh37488,928,787 - 88,998,929 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36489,147,844 - 89,217,953 (+)NCBINCBI36Build 36hg18NCBI36
Build 34489,285,998 - 89,356,107NCBI
Celera486,220,746 - 86,290,863 (+)NCBICelera
Cytogenetic Map4q22.1NCBI
HuRef484,675,256 - 84,745,398 (+)NCBIHuRef
CHM1_1488,905,594 - 88,975,728 (+)NCBICHM1_1
T2T-CHM13v2.0491,334,123 - 91,404,269 (+)NCBIT2T-CHM13v2.0
Pkd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8145,541,821 - 5,585,140 (-)NCBIGRCr8
mRatBN7.2145,237,135 - 5,280,455 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl145,237,135 - 5,280,825 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx145,198,260 - 5,241,484 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,498,456 - 6,541,680 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0145,192,618 - 5,233,125 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0146,602,004 - 6,645,257 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl146,602,004 - 6,645,257 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0146,581,342 - 6,624,595 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4146,349,519 - 6,392,988 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera145,376,651 - 5,418,198 (-)NCBICelera
Cytogenetic Map14p22NCBI
Pkd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554741,833,701 - 1,868,817 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554741,831,221 - 1,868,170 (-)NCBIChiLan1.0ChiLan1.0
PKD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2386,009,202 - 86,079,254 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1486,271,612 - 86,341,660 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0480,295,243 - 80,365,271 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1491,019,739 - 91,088,858 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl491,019,734 - 91,086,775 (+)Ensemblpanpan1.1panPan2
PKD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13211,383,441 - 11,437,603 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3211,383,424 - 11,435,438 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3230,517,045 - 30,571,324 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03211,435,888 - 11,490,399 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3211,435,683 - 11,490,397 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13211,519,719 - 11,571,825 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03211,345,806 - 11,399,834 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03228,555,188 - 28,609,469 (-)NCBIUU_Cfam_GSD_1.0
Pkd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052851,657,007 - 1,709,229 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493690576,781 - 128,995 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8131,005,407 - 131,058,932 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18131,002,973 - 131,058,932 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28140,233,075 - 140,289,084 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PKD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1736,369,226 - 36,445,713 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl736,369,524 - 36,443,612 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603715,121,642 - 15,193,435 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248724,539,847 - 4,594,793 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248724,539,965 - 4,592,004 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pkd2
2624 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:701
Count of miRNA genes:487
Interacting mature miRNAs:555
Transcripts:ENSMUST00000086831, ENSMUST00000130931, ENSMUST00000133540
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045978Tir10_mtrypanosome infection response 10 (mouse)Not determined598019649114021986Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5103047866115538059Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
25314317Sccor3_msynaptonemal complex length to mean MLH1 count ratio 3 (mouse)5104347866114738061Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined598019649116876624Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576280786110280917Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
1357886Diht_mdopamine-induced hypothermia (mouse)Not determined5104498738115101540Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572418876106419011Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579539640113539786Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576190263110190479Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576445064110445225Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576445064110445225Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576445064110445225Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
1301877Bbaa3_mB.burgdorferi-associated arthritis 3 (mouse)Not determined599455285112465722Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576280786110280917Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576445064110445225Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576280786110280917Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse

Markers in Region
AF014010  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,503,708 - 104,503,805UniSTSGRCm38
MGSCv375104,932,727 - 104,932,824UniSTSGRCm37
Celera5101,815,707 - 101,815,807UniSTS
Cytogenetic Map5E5UniSTS
cM Map555.0UniSTS
Whitehead/MRC_RH51236.44UniSTS
RH141583  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,505,513 - 104,505,688UniSTSGRCm38
MGSCv375104,934,532 - 104,934,707UniSTSGRCm37
Celera5101,817,531 - 101,817,707UniSTS
Cytogenetic Map5E5UniSTS
cM Map555.0UniSTS
Pkd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,502,346 - 104,503,572UniSTSGRCm38
MGSCv375104,931,365 - 104,932,591UniSTSGRCm37
Celera5101,814,345 - 101,815,571UniSTS
Cytogenetic Map5E5UniSTS
cM Map555.0UniSTS
cM Map555.0UniSTS
cM Map555.0UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS
Pkd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,503,936 - 104,504,052UniSTSGRCm38
MGSCv375104,932,955 - 104,933,071UniSTSGRCm37
Cytogenetic Map5E5UniSTS
Pkd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,505,003 - 104,505,130UniSTSGRCm38
MGSCv375104,934,022 - 104,934,149UniSTSGRCm37
Celera5101,817,021 - 101,817,148UniSTS
Cytogenetic Map5E5UniSTS
Pkd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,486,764 - 104,486,923UniSTSGRCm38
MGSCv375104,915,783 - 104,915,942UniSTSGRCm37
Cytogenetic Map5E5UniSTS
cM Map555.0UniSTS
Pkd2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385104,504,825 - 104,504,923UniSTSGRCm38
MGSCv375104,933,844 - 104,933,942UniSTSGRCm37
Celera5101,816,843 - 101,816,941UniSTS
Cytogenetic Map5E5UniSTS
cM Map555.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001784633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003955591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC124106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF014010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF242389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV517098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU705556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX566027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ609779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000086831   ⟹   ENSMUSP00000084041
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5104,607,316 - 104,653,685 (+)Ensembl
GRCm38.p6 Ensembl5104,459,450 - 104,505,819 (+)Ensembl
Ensembl Acc Id: ENSMUST00000130931
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5104,607,436 - 104,638,186 (+)Ensembl
GRCm38.p6 Ensembl5104,459,570 - 104,490,320 (+)Ensembl
Ensembl Acc Id: ENSMUST00000133540
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5104,640,637 - 104,649,215 (+)Ensembl
GRCm38.p6 Ensembl5104,492,771 - 104,501,349 (+)Ensembl
RefSeq Acc Id: NM_008861   ⟹   NP_032887
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395104,607,323 - 104,653,685 (+)NCBI
GRCm385104,459,457 - 104,505,819 (+)NCBI
MGSCv375104,888,476 - 104,934,838 (+)RGD
Celera5101,769,092 - 101,817,838 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534815   ⟹   XP_006534878
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395104,599,379 - 104,653,685 (+)NCBI
GRCm385104,453,982 - 104,505,819 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001784633
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395104,599,379 - 104,653,685 (+)NCBI
GRCm385104,453,982 - 104,505,819 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003955591
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395104,599,379 - 104,653,685 (+)NCBI
GRCm385104,453,982 - 104,505,819 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032887   ⟸   NM_008861
- UniProtKB: Q9Z193 (UniProtKB/Swiss-Prot),   Q9QWP0 (UniProtKB/Swiss-Prot),   Q9ES37 (UniProtKB/Swiss-Prot),   Q8BPR6 (UniProtKB/Swiss-Prot),   E9QQA3 (UniProtKB/Swiss-Prot),   E9Q4F6 (UniProtKB/Swiss-Prot),   C0KJK2 (UniProtKB/Swiss-Prot),   Q9Z194 (UniProtKB/Swiss-Prot),   O35245 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534878   ⟸   XM_006534815
- Peptide Label: isoform X1
- UniProtKB: O35245 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000084041   ⟸   ENSMUST00000086831
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35245-F1-model_v2 AlphaFold O35245 1-966 view protein structure

Promoters
RGD ID:6887358
Promoter ID:EPDNEW_M7130
Type:multiple initiation site
Name:Pkd2_1
Description:Mus musculus polycystic kidney disease 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385104,459,553 - 104,459,613EPDNEW
RGD ID:6838056
Promoter ID:MM_KWN:43157
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000064001,   OTTMUST00000064002,   OTTMUST00000064003,   OTTMUST00000064005,   UC008YKL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365104,888,276 - 104,889,242 (+)MPROMDB
RGD ID:6838053
Promoter ID:MM_KWN:43158
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney
Transcripts:OTTMUST00000064004
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365104,921,819 - 104,922,319 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1099818 AgrOrtholog
Ensembl Genes ENSMUSG00000034462 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000086831 ENTREZGENE
  ENSMUST00000086831.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot
  1.20.120.350 UniProtKB/Swiss-Prot
  1.20.5.340 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  PKD1_2_channel UniProtKB/Swiss-Prot
  PKD_2 UniProtKB/Swiss-Prot
  Polycystin UniProtKB/Swiss-Prot
  Polycystin_dom UniProtKB/Swiss-Prot
  Volt_channel_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:18764 UniProtKB/Swiss-Prot
MGD MGI:1099818 ENTREZGENE
NCBI Gene 18764 ENTREZGENE
PANTHER POLYCYSTIN FAMILY MEMBER UniProtKB/Swiss-Prot
  POLYCYSTIN-2 UniProtKB/Swiss-Prot
Pfam Fer4_24 UniProtKB/Swiss-Prot
  PKD_channel UniProtKB/Swiss-Prot
  Polycystin_dom UniProtKB/Swiss-Prot
PhenoGen Pkd2 PhenoGen
PRINTS POLYCYSTIN2 UniProtKB/Swiss-Prot
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
  Voltage-gated potassium channels UniProtKB/Swiss-Prot
UniProt C0KJK2 ENTREZGENE
  E9Q4F6 ENTREZGENE
  E9QQA3 ENTREZGENE
  O35245 ENTREZGENE, UniProtKB/Swiss-Prot
  Q8BPR6 ENTREZGENE
  Q9ES37 ENTREZGENE
  Q9QWP0 ENTREZGENE
  Q9Z193 ENTREZGENE
  Q9Z194 ENTREZGENE
UniProt Secondary C0KJK2 UniProtKB/Swiss-Prot
  E9Q4F6 UniProtKB/Swiss-Prot
  E9QQA3 UniProtKB/Swiss-Prot
  Q8BPR6 UniProtKB/Swiss-Prot
  Q9ES37 UniProtKB/Swiss-Prot
  Q9QWP0 UniProtKB/Swiss-Prot
  Q9Z193 UniProtKB/Swiss-Prot
  Q9Z194 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-05-07 Pkd2  polycystin 2, transient receptor potential cation channel  Pkd2  polycystic kidney disease 2  Symbol and/or name change 5135510 APPROVED