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Gene: Cldn2 (claudin 2) Mus musculus

Analyze

Symbol:

Cldn2

Name:

claudin 2

RGD ID:

1558320

MGI Page

MGI

Description:

Enables identical protein binding activity and paracellular tight junction channel activity. Involved in several processes, including calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; innate immune response in mucosa; and regulation of intestinal absorption. Located in bicellular tight junction. Is expressed in alimentary system; brain; genitourinary system; and submandibular gland primordium. Orthologous to human CLDN2 (claudin 2).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

AL022813; claudin-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CLDN2 (claudin 2)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Cldn2 (claudin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cldn2 (claudin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CLDN2 (claudin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CLDN2 (claudin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cldn2 (claudin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CLDN2 (claudin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CLDN2 (claudin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cldn2 (claudin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CLDN2 (claudin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Cldn2 (claudin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cldn2 (claudin 2)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|ZFIN)
Xenopus tropicalis (tropical clawed frog):	cldn2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	138,701,552 - 138,712,135 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	138,701,577 - 138,712,135 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	139,800,808 - 139,811,386 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	139,800,828 - 139,811,386 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	136,335,367 - 136,345,923 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	135,147,192 - 135,157,748 (+)	NCBI		MGSCv36	mm8
Celera	X	123,063,444 - 123,074,101 (+)	NCBI		Celera
Cytogenetic Map	X	F1	NCBI
cM Map	X	61.35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

AZOOSPERMIA, OBSTRUCTIVE, WITH NEPHROLITHIASIS (ISO)

Charcot-Marie-Tooth disease type X (ISO)

factor VIII deficiency (ISO)

male infertility (ISO)

pancreatitis (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (EXP)

(R,R,R)-alpha-tocopherol (ISO)

17alpha-ethynylestradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrobenzenesulfonic acid (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

2,6-di-tert-butyl-4-methylphenol (EXP)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (EXP)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP,ISO)

acadesine (ISO)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

aldrin (EXP)

all-trans-retinoic acid (EXP)

Ammothamnine (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

buta-1,3-diene (EXP)

butanal (ISO)

cadmium dichloride (ISO)

cantharidin (ISO)

carbon nanotube (EXP)

CGP 52608 (ISO)

chlordecone (EXP)

chloroquine (ISO)

cholic acid (ISO)

cisplatin (ISO)

cobalt atom (EXP)

cobalt dichloride (ISO)

copper(II) sulfate (EXP)

cordycepin (ISO)

corticosterone (EXP)

Cuprizon (ISO)

curcumin (ISO)

cyclosporin A (ISO)

deguelin (ISO)

deoxynivalenol (EXP)

dextran sulfate (EXP)

diallyl disulfide (ISO)

diallyl trisulfide (ISO)

dibenzofurans (EXP)

dieldrin (ISO)

diiodine (EXP)

doxorubicin (ISO)

endosulfan (ISO)

epoxiconazole (EXP)

ethylparaben (ISO)

flutamide (ISO)

folic acid (EXP)

fulvestrant (ISO)

furan (ISO)

gefitinib (EXP)

genistein (ISO)

glycidol (ISO)

glyphosate (ISO)

hydrogen peroxide (ISO)

inulin (EXP)

irinotecan (ISO)

iron atom (ISO)

iron(0) (ISO)

isoniazide (ISO)

kaempferol (ISO)

lipopolysaccharide (ISO)

LY294002 (ISO)

maleic acid (ISO)

metformin (ISO)

methapyrilene (ISO)

methidathion (EXP)

mono(2-ethylhexyl) phthalate (EXP)

morphine (EXP)

N,N-diethyl-m-toluamide (ISO)

naphthalene (EXP)

ochratoxin A (EXP,ISO)

okadaic acid (ISO)

ozone (EXP)

p-chloromercuribenzenesulfonic acid (EXP)

paracetamol (ISO)

PCB138 (EXP)

pentachlorophenol (EXP)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

permethrin (EXP,ISO)

phenethyl caffeate (ISO)

phenobarbital (EXP)

pirinixic acid (EXP,ISO)

potassium bromate (ISO)

potassium dichromate (ISO)

Pyridostigmine bromide (EXP)

resveratrol (ISO)

rotenone (ISO)

sanguinarine (ISO)

SB 203580 (ISO)

silicon dioxide (EXP)

sodium arsenite (EXP,ISO)

sodium dichromate (EXP,ISO)

solasodine (EXP,ISO)

streptozocin (ISO)

sulfasalazine (ISO)

tamoxifen (EXP)

tetracycline (ISO)

tetraphene (EXP)

thioacetamide (ISO)

urethane (ISO)

valdecoxib (ISO)

valproic acid (EXP,ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bicellular tight junction assembly (IBA)

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (IBA,IDA)

cell-cell adhesion (IMP)

innate immune response in mucosa (IMP)

paracellular transport (IDA,IMP)

regulation of bile acid secretion (IMP)

regulation of intestinal D-glucose absorption (IMP)

regulation of intestinal lipid absorption (IMP)

Cellular Component

bicellular tight junction (IBA,IDA,IMP)

cell junction (ISO)

cell-cell junction (ISO)

intracellular membrane-bounded organelle (ISO)

membrane (NAS)

nucleoplasm (ISO)

plasma membrane (IBA,IEA)

tight junction (IDA)

Molecular Function

identical protein binding (IPI)

paracellular tight junction channel activity (IDA)

protein binding (IPI)

structural molecule activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

hepatitis C pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal enzyme/coenzyme level (IAGP)

abnormal renal reabsorption (IAGP)

abnormal renal sodium ion transport (IAGP)

abnormal renal sodium reabsorption (IAGP)

abnormal renal water reabsorption (IAGP)

decreased urine osmolality (IAGP)

hypoxia (IAGP)

increased blood urea nitrogen level (IAGP)

increased circulating creatinine level (IAGP)

increased oxygen consumption (IAGP)

increased susceptibility to kidney reperfusion injury (IAGP)

increased urine calcium level (IAGP)

increased urine sodium level (IAGP)

polyuria (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.	Morita K, etal., Proc Natl Acad Sci U S A 1999 Jan 19;96(2):511-6.
4.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7671812	PMID:9647647	PMID:9786950	PMID:9824655	PMID:10349636	PMID:10508613	PMID:10562289	PMID:10601346	PMID:11042159	PMID:11076861	PMID:11923212	PMID:11934881
PMID:12432083	PMID:12477932	PMID:12700140	PMID:14698084	PMID:15366020	PMID:15366421	PMID:15489334	PMID:15569684	PMID:16141072	PMID:16141073	PMID:16520537	PMID:16602821
PMID:16618389	PMID:17075866	PMID:17138657	PMID:17182288	PMID:18036336	PMID:18287530	PMID:18287559	PMID:18346943	PMID:18480174	PMID:19114638	PMID:19494835	PMID:19521566
PMID:19538287	PMID:19706201	PMID:19914171	PMID:20177070	PMID:20214989	PMID:20385797	PMID:20562862	PMID:20602571	PMID:20727355	PMID:21098027	PMID:21267068	PMID:21402740
PMID:21677750	PMID:21688348	PMID:21771795	PMID:21873635	PMID:22155109	PMID:22178591	PMID:22268650	PMID:22275141	PMID:22645303	PMID:22767581	PMID:22819673	PMID:22825868
PMID:22946046	PMID:23089202	PMID:23303670	PMID:23306855	PMID:23369528	PMID:24049145	PMID:24436330	PMID:24662742	PMID:24670427	PMID:25068494	PMID:25078604	PMID:26212084
PMID:26332085	PMID:27214555	PMID:28605031	PMID:28618266	PMID:28939759	PMID:29617460	PMID:30899070	PMID:31481470	PMID:31534052	PMID:32149733	PMID:32496646	PMID:32516134
PMID:33069918	PMID:34099675	PMID:34321999	PMID:34737342	PMID:34810264	PMID:36227903	PMID:37460613	PMID:37575484	PMID:37815870	PMID:38412124

Genomics

Comparative Map Data

Cldn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	138,701,552 - 138,712,135 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	138,701,577 - 138,712,135 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	139,800,808 - 139,811,386 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	139,800,828 - 139,811,386 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	136,335,367 - 136,345,923 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	135,147,192 - 135,157,748 (+)	NCBI		MGSCv36	mm8
Celera	X	123,063,444 - 123,074,101 (+)	NCBI		Celera
Cytogenetic Map	X	F1	NCBI
cM Map	X	61.35	NCBI

CLDN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	106,900,164 - 106,930,861 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	106,900,164 - 106,930,861 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	106,143,394 - 106,174,091 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	106,050,290 - 106,060,747 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	105,969,778 - 105,980,236	NCBI
Celera	X	106,614,779 - 106,645,477 (+)	NCBI		Celera
Cytogenetic Map	X	q22.3	NCBI
HuRef	X	95,771,755 - 95,802,061 (+)	NCBI		HuRef
CHM1_1	X	106,054,200 - 106,084,897 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	105,336,674 - 105,367,377 (+)	NCBI		T2T-CHM13v2.0

Cldn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	108,248,383 - 108,258,847 (+)	NCBI		GRCr8
mRatBN7.2	X	103,459,870 - 103,473,794 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	103,459,780 - 103,474,838 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	105,592,416 - 105,602,750 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	109,091,151 - 109,101,485 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	106,655,156 - 106,665,516 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	111,122,552 - 111,133,188 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	111,122,552 - 111,137,769 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	53,456,573 - 53,472,568 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	127,538,685 - 127,549,019 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	44,457,488 - 44,467,822 (-)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

Cldn2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955490	9,136,986 - 9,145,034 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955490	9,137,157 - 9,180,945 (-)	NCBI	ChiLan1.0	ChiLan1.0

CLDN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	106,410,924 - 106,414,386 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	106,414,543 - 106,417,987 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	96,020,274 - 96,031,157 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	106,405,707 - 106,408,516 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	106,405,879 - 106,406,571 (+)	Ensembl	panpan1.1		panPan2

CLDN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	80,456,313 - 80,491,944 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	80,483,333 - 80,530,012 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	66,603,000 - 66,603,952 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	82,119,947 - 82,128,336 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	79,592,206 - 79,593,158 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	81,302,056 - 81,303,008 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	81,081,052 - 81,082,004 (+)	NCBI		UU_Cfam_GSD_1.0

Cldn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	79,829,508 - 79,839,529 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	7,820,410 - 7,821,102 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	7,818,436 - 7,828,444 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CLDN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	87,321,152 - 87,355,721 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	87,352,695 - 87,355,724 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

CLDN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	94,752,552 - 94,762,247 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666065	19,835,977 - 19,848,312 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cldn2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624803	9,839,911 - 9,846,367 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624803	9,839,916 - 9,849,891 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cldn2
273 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1882
Count of miRNA genes:	820
Interacting mature miRNAs:	1042
Transcripts:	ENSMUST00000054889, ENSMUST00000135224, ENSMUST00000172779
Prediction methods:	Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
13208552	Wght12_m	weight 12 (mouse)					X	94043606	149782996	Mouse
1558900	Bw3_m	body weight QTL 3 (mouse)			Not determined		X	133540040	165298595	Mouse
13208556	Lgth14_m	body length 14 (mouse)					X	94043606	149782996	Mouse
13824980	Ferq1_m	genetic fertility QTL 1 (mouse)					X	54045360	148782996	Mouse
25314309	Syncl5_m	synaptonemal complex length 5 (mouse)					X	121909697	152582996	Mouse
13824981	Svwq2_m	seminal vesicle weight QTL 2 (mouse)					X	128900749	153782996	Mouse
1301209	Cia19_m	collagen induced arthritis 19 (mouse)			Not determined		X	120993165	160213038	Mouse
10412164	Cmv2_m	cytomegalovirus resistance 2 (mouse)			Not determined		X	125685149	159685269	Mouse
1357823	Spha3_m	sperm head anomaly 3 (mouse)			Not determined		X	102055848	162758941	Mouse
1357433	Dbts2_m	diabetes 2 (mouse)			Not determined		X	7226295	150107038	Mouse
4141665	Mhysq2_m	male hybrid sterility QTL 2 (mouse)			Not determined			71453852	139203212	Mouse
1301276	Tswt_m	testis weight (mouse)			Not determined		X	138376411	150789338	Mouse

Markers in Region

Cldn2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	139,808,708 - 139,809,400	UniSTS	GRCm38
MGSCv37	X	136,343,247 - 136,343,939	UniSTS	GRCm37
Celera	X	123,071,382 - 123,072,074	UniSTS
Cytogenetic Map	X	F1	UniSTS
cM Map	X		UniSTS

RH125356

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	139,810,527 - 139,810,726	UniSTS	GRCm38
MGSCv37	X	136,345,066 - 136,345,265	UniSTS	GRCm37
Celera	X	123,073,201 - 123,073,400	UniSTS
Cytogenetic Map	X	F1	UniSTS

Cldn2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	X	F1	UniSTS

Cldn2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	139,808,964 - 139,809,442	UniSTS	GRCm38
MGSCv37	X	136,343,503 - 136,343,981	UniSTS	GRCm37
Celera	X	123,071,638 - 123,072,116	UniSTS
Cytogenetic Map	X	F1	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001410421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_016675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006528486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006528487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006528488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006528489	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF072128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI174044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK004990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL672243	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC015252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY075485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000054889 ⟹ ENSMUSP00000054219

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	X	138,701,577 - 138,712,135 (+)	Ensembl
GRCm38.p6 Ensembl	X	139,800,828 - 139,811,386 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000135224 ⟹ ENSMUSP00000121152

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	X	138,706,830 - 138,709,850 (+)	Ensembl
GRCm38.p6 Ensembl	X	139,806,081 - 139,809,101 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000172779 ⟹ ENSMUSP00000134644

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	X	138,703,536 - 138,709,462 (+)	Ensembl
GRCm38.p6 Ensembl	X	139,802,787 - 139,808,713 (+)	Ensembl

RefSeq Acc Id:

NM_001410421 ⟹ NP_001397350

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	138,701,736 - 138,712,135 (+)	NCBI

RefSeq Acc Id:

NM_016675 ⟹ NP_057884

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	138,701,552 - 138,712,135 (+)	NCBI
GRCm38	X	139,800,808 - 139,811,386 (+)	ENTREZGENE
MGSCv37	X	136,335,367 - 136,345,923 (+)	RGD
Celera	X	123,063,424 - 123,074,103 (+)	ENTREZGENE
cM Map	X		ENTREZGENE

Sequence:

show sequence

GCAATCTTTTCCAGCCTCCAAGGGTTTCATTCCCATCTGTAAGAAGGCTCAGAGTTACAGGTGG
AGTTTACAAAGCTGTGGCTAATAATTAGAAATCCCTTATCACCACAGCTTGTGACCCCTTGGAC
CCCGTTCGCCTTTCTCTGGACCTAGTCCTTGTCCCCAGAAGCGTCTCTTCCAGAGCTCTTCGAA
AGGACGGCTCCGTTTTCTAGATGCCTTCTTGAGCCTGCTTGTGGCCACCCACAGATACTTGTAA
GGAGGAAAGAAGTCAGCTTGCCAGAGACACTGTGAAATAAGGGATTAGAGGCTCGGATCCAAGA
AGCAAGAGCAGCAGCCAAACGACAAGCAAACAGGCTCCGAAGATACTTCTACTGAGAGGTCTGC
CATGGCCTCCCTTGGCGTCCAACTGGTGGGCTACATCCTAGGCCTTTTGGGGCTGTTAGGCACA
TCCATTGCCATGCTGCTTCCCAACTGGCGAACGAGTTCCTATGTTGGTGCCAGCATTGTGACGG
CGGTTGGCTTTTCCAAGGGCCTCTGGATGGAGTGTGCGACACACAGCACAGGCATCACCCAGTG
CGATATCTACAGTACCCTTTTAGGACTTCCTGCTGACATCCAGGCTGCCCAGGCCATGATGGTG
ACGTCCAGTGCAATGTCCTCGCTGGCTTGTATTATCTCTGTGGTGGGCATGAGATGCACCGTGT
TCTGCCAGGATTCTCGAGCTAAGGACAGAGTGGCTGTAGTGGGTGGAGTCTTTTTCATCCTTGG
TGGCATCCTGGGCTTTATCCCAGTTGCTTGGAATCTTCATGGCATCCTTCGGGACTTCTACTCG
CCGCTGGTTCCTGACAGCATGAAATTTGAGATTGGAGAGGCTCTGTACTTGGGCATCATCTCAG
CCCTGTTTTCTTTGGTAGCCGGAGTCATCCTTTGCTTTTCCTGCTCGCCCCAGGGCAATCGTAC
CAACTACTATGATGGCTACCAGGCCCAGCCTCTTGCCACTAGGAGCTCTCCAAGATCTGCTCAA
CAGCCCAAAGCCAAGAGTGAGTTCAACTCATACAGCCTGACTGGGTATGTGTGAAGAACCAGGG
GCCAGAGCTGGGGGTAGGGTGGGGTAGTGGCTGGGACTATATATATAAAAAAAAGCAGTGGACA
ATGCCCCCAGGGTCACAAGCAAAGGACATTGCCACTGAATCATGTGTAAGGTGCTGCTGAGGGT
AGAATGACTTTGGCCATTGGATGGAGTGAAGGCAGAGATGAGAAGAGGGGTGTCAGCATGTAGA
TGGCATTGCCAAGGACGCTTGCCAAGCTAGCTTTTCTATTTCCCTCACCTGACCTCACTAAAGT
ACCTCCTGTGCTTTGAATGCTCAACCCAAAAGCCCAAATCCCATCTCTGCCACTTTAGGCTATG
CCCAGAGGCTCTCTTCTGCCCTTTGGTTTACTTGGAGATCTGTCCCCAAACCAATCATATCCTG
TTGACTAATCACCTGTGATCAAAAGACCCTCTCCCTCTGGCTGAGGTTGGCTCTTAACTCAATT
ACTAAGGGACAGAGAGAAGAAAGAGTGGTGGCTTCTGTGAGGACATTTCTAGCTCCCTTCTCAA
ATCTCCAGCCAAAGAAATGGATTAGTCAGTAATGGGCCCTGAAGCTTCTCTTCCAGTTTTGCTA
TGAATGCAGTATGTCCAGACTGCATTGTGAATGAACTGAAGGAAAGCTATCTCATGGCATCCAG
CAGAATACAGCTGGGTGCAGGATGGGAGGCAACCTGGGATCTAAAGAAACAAAACAAACAGCAA
AACCCGACAGAATCCCTTCTCAGGCCATCTCCTATAATTCCCGTACATTTGTGGGTCAGGGATG
GAAGCACTGCTAAGGAAAGCACAAGAAGCCAAGGGAAAGCACATGGCTGCTGCCCTCTGACTCC
ACAGAGGAATTGCCCAGAAGCCAAGGTGAACACGGACCACTGAAAGCTCTGCCTCCCACTGGGG
TGTCTGACCCAGCTTCCTGCTAAACCACAAGACTTGGAGCCCTAGACAAGGGTTTCCTTAAGGA
CAATAAACCAGTTTTTCTAGAACTGCCCTTTGACATGCGAGTTGCAGAAGGCTTAAAAAAAATA
CTACCCTTTAGCCCTGACCGAGAAAGAATAAGGGCTTGGGTATCAAAGAACCGGACAGAGATGT
GTGGTAGCTGTTATGTGTGCTCCTACTGTTTCAGAGAGGCAGCCCTACCAGATACTTTAGACTT
GATGGAAGACCAACCCATCAGGGTCTATGTCTCAGCACTACAGAGCCTCTGAAAGACCACAGCA
CCAGAGAGGTCCTTTGTCACTTTTCACACTTGAGTCATCGCCCATCAGAAGATACTCTCACAGG
TATGCAAAGTCTCCAGTGTGGAACATCTGTGACCAAGGTGTTGTGTTCATGACCTGAGCAATTG
GTGAACTTCTGCCTGGGATTGTGCTTGAGGTGGGAGAACGGAGACTGGTTCCCTGTCCAACAGT
TTTATTTCCACGGTCTTAAAATGCTCCATTTCTTCTGTGGTAGATGGGGGTCATAAACCAGAGA
CATTTCCCCACCACCACCAGCTTAATATCACCAGCTTCAGAAGATCCCCAGCGCACCTCATCAA
AACTTCAGCACCGGCAAGAGAGGCCCATATGTGAGGTTTCCCTTAACATGCCTTTCCTATTTCC
ACCATATTACTTGTGTTCAAGCTGATATGCTGACCTGGAAGCCATTTCCTTTTAACTAAGTCAT
CCCCATGCTTGGAGAACTTGCTCATTGAGCCTTCTCTGACCACTCCTTCCTGTTCTTTCCTTTC
CCTCCTCCAACTCCCAATATATAAATTGCCTAATCCTCATCATTCATAATTTTGATTGATAGTT
TATAGTTCTTGTATGTGCATTTGTGTGTGACTCTATCCGTCTGTCTGTCTGTGTGATCTCAAAA
GTTCACTGTAAGTACTTGGAGGGCAATTGCTATATCTTAGACCTGTCCATATGTATACCCAAGA
CTGTAACAGTGCTGGGCACACACAAGGTGATCAATAAACGGATGTTGATTGAGTAAAAAAAAAA
AAAAAAA

hide sequence

RefSeq Acc Id:

XM_006528486 ⟹ XP_006528549

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	138,701,555 - 138,712,135 (+)	NCBI
GRCm38	X	139,800,809 - 139,811,386 (+)	NCBI

Sequence:

show sequence

CCGCAATCTTTTCCAGCCTCCAAGGGTTTCATTCCCATCTGTAAGAAGGCTCAGAGTTACAGGT
GGAGTTTACAAAGCTGTGGCTAATAATTAGAAATCCCTTATCACCACAGCTTGTGACCCCTTGG
ACCCCGTTCGCCTTTCTCTGGACCTAGTCCTTGTCCCCAGAAGCGTCTCTTCCAGAGCTCTTCG
AAAGGACGGCTCCGTGAGTATCTGGTCGTTTTCTAGATGCCTTCTTGAGCCTGCTTGTGGCCAC
CCACAGATACTTGTAAGGAGGAAAGAAGTCAGCTTGCCAGAGACACTGTGAAATAAGGGATTAG
AGGCTCGGATCCAAGAAGCAAGAGCAGCAGCCAAACGACAAGCAAACAGGCTCCGAAGATACTT
CTACTGAGAGGTCTGCCATGGCCTCCCTTGGCGTCCAACTGGTGGGCTACATCCTAGGCCTTTT
GGGGCTGTTAGGCACATCCATTGCCATGCTGCTTCCCAACTGGCGAACGAGTTCCTATGTTGGT
GCCAGCATTGTGACGGCGGTTGGCTTTTCCAAGGGCCTCTGGATGGAGTGTGCGACACACAGCA
CAGGCATCACCCAGTGCGATATCTACAGTACCCTTTTAGGACTTCCTGCTGACATCCAGGCTGC
CCAGGCCATGATGGTGACGTCCAGTGCAATGTCCTCGCTGGCTTGTATTATCTCTGTGGTGGGC
ATGAGATGCACCGTGTTCTGCCAGGATTCTCGAGCTAAGGACAGAGTGGCTGTAGTGGGTGGAG
TCTTTTTCATCCTTGGTGGCATCCTGGGCTTTATCCCAGTTGCTTGGAATCTTCATGGCATCCT
TCGGGACTTCTACTCGCCGCTGGTTCCTGACAGCATGAAATTTGAGATTGGAGAGGCTCTGTAC
TTGGGCATCATCTCAGCCCTGTTTTCTTTGGTAGCCGGAGTCATCCTTTGCTTTTCCTGCTCGC
CCCAGGGCAATCGTACCAACTACTATGATGGCTACCAGGCCCAGCCTCTTGCCACTAGGAGCTC
TCCAAGATCTGCTCAACAGCCCAAAGCCAAGAGTGAGTTCAACTCATACAGCCTGACTGGAGAG
GCAGCCCTACCAGATACTTTAGACTTGATGGAAGACCAACCCATCAGGGTCTATGTCTCAGCAC
TACAGAGCCTCTGAAAGACCACAGCACCAGAGAGGTCCTTTGTCACTTTTCACACTTGAGTCAT
CGCCCATCAGAAGATACTCTCACAGGTATGCAAAGTCTCCAGTGTGGAACATCTGTGACCAAGG
TGTTGTGTTCATGACCTGAGCAATTGGTGAACTTCTGCCTGGGATTGTGCTTGAGGTGGGAGAA
CGGAGACTGGTTCCCTGTCCAACAGTTTTATTTCCACGGTCTTAAAATGCTCCATTTCTTCTGT
GGTAGATGGGGGTCATAAACCAGAGACATTTCCCCACCACCACCAGCTTAATATCACCAGCTTC
AGAAGATCCCCAGCGCACCTCATCAAAACTTCAGCACCGGCAAGAGAGGCCCATATGTGAGGTT
TCCCTTAACATGCCTTTCCTATTTCCACCATATTACTTGTGTTCAAGCTGATATGCTGACCTGG
AAGCCATTTCCTTTTAACTAAGTCATCCCCATGCTTGGAGAACTTGCTCATTGAGCCTTCTCTG
ACCACTCCTTCCTGTTCTTTCCTTTCCCTCCTCCAACTCCCAATATATAAATTGCCTAATCCTC
ATCATTCATAATTTTGATTGATAGTTTATAGTTCTTGTATGTGCATTTGTGTGTGACTCTATCC
GTCTGTCTGTCTGTGTGATCTCAAAAGTTCACTGTAAGTACTTGGAGGGCAATTGCTATATCTT
AGACCTGTCCATATGTATACCCAAGACTGTAACAGTGCTGGGCACACACAAGGTGATCAATAAA
CGGATGTTGATTGAGTAA

hide sequence

RefSeq Acc Id:

XM_006528487 ⟹ XP_006528550

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	138,701,555 - 138,712,135 (+)	NCBI
GRCm38	X	139,800,809 - 139,811,386 (+)	NCBI

Sequence:

show sequence

CCGCAATCTTTTCCAGCCTCCAAGGGTTTCATTCCCATCTGTAAGAAGGCTCAGAGTTACAGGT
GGAGTTTACAAAGCTGTGGCTAATAATTAGAAATCCCTTATCACCACAGCTTGTGACCCCTTGG
ACCCCGTTCGCCTTTCTCTGGACCTAGTCCTTGTCCCCAGAAGCGTCTCTTCCAGAGCTCTTCG
AAAGGACGGCTCCGTTTTCTAGATGCCTTCTTGAGCCTGCTTGTGGCCACCCACAGATACTTGT
AAGGAGGAAAGAAGTCAGCTTGCCAGAGACACTGTGAAATAAGGGATTAGAGGCTCGGATCCAA
GAAGCAAGAGCAGCAGCCAAACGACAAGCAAACAGGCTCCGAAGATACTTCTACTGAGAGGTCT
GCCATGGCCTCCCTTGGCGTCCAACTGGTGGGCTACATCCTAGGCCTTTTGGGGCTGTTAGGCA
CATCCATTGCCATGCTGCTTCCCAACTGGCGAACGAGTTCCTATGTTGGTGCCAGCATTGTGAC
GGCGGTTGGCTTTTCCAAGGGCCTCTGGATGGAGTGTGCGACACACAGCACAGGCATCACCCAG
TGCGATATCTACAGTACCCTTTTAGGACTTCCTGCTGACATCCAGGCTGCCCAGGCCATGATGG
TGACGTCCAGTGCAATGTCCTCGCTGGCTTGTATTATCTCTGTGGTGGGCATGAGATGCACCGT
GTTCTGCCAGGATTCTCGAGCTAAGGACAGAGTGGCTGTAGTGGGTGGAGTCTTTTTCATCCTT
GGTGGCATCCTGGGCTTTATCCCAGTTGCTTGGAATCTTCATGGCATCCTTCGGGACTTCTACT
CGCCGCTGGTTCCTGACAGCATGAAATTTGAGATTGGAGAGGCTCTGTACTTGGGCATCATCTC
AGCCCTGTTTTCTTTGGTAGCCGGAGTCATCCTTTGCTTTTCCTGCTCGCCCCAGGGCAATCGT
ACCAACTACTATGATGGCTACCAGGCCCAGCCTCTTGCCACTAGGAGCTCTCCAAGATCTGCTC
AACAGCCCAAAGCCAAGAGTGAGTTCAACTCATACAGCCTGACTGGAGAGGCAGCCCTACCAGA
TACTTTAGACTTGATGGAAGACCAACCCATCAGGGTCTATGTCTCAGCACTACAGAGCCTCTGA
AAGACCACAGCACCAGAGAGGTCCTTTGTCACTTTTCACACTTGAGTCATCGCCCATCAGAAGA
TACTCTCACAGGTATGCAAAGTCTCCAGTGTGGAACATCTGTGACCAAGGTGTTGTGTTCATGA
CCTGAGCAATTGGTGAACTTCTGCCTGGGATTGTGCTTGAGGTGGGAGAACGGAGACTGGTTCC
CTGTCCAACAGTTTTATTTCCACGGTCTTAAAATGCTCCATTTCTTCTGTGGTAGATGGGGGTC
ATAAACCAGAGACATTTCCCCACCACCACCAGCTTAATATCACCAGCTTCAGAAGATCCCCAGC
GCACCTCATCAAAACTTCAGCACCGGCAAGAGAGGCCCATATGTGAGGTTTCCCTTAACATGCC
TTTCCTATTTCCACCATATTACTTGTGTTCAAGCTGATATGCTGACCTGGAAGCCATTTCCTTT
TAACTAAGTCATCCCCATGCTTGGAGAACTTGCTCATTGAGCCTTCTCTGACCACTCCTTCCTG
TTCTTTCCTTTCCCTCCTCCAACTCCCAATATATAAATTGCCTAATCCTCATCATTCATAATTT
TGATTGATAGTTTATAGTTCTTGTATGTGCATTTGTGTGTGACTCTATCCGTCTGTCTGTCTGT
GTGATCTCAAAAGTTCACTGTAAGTACTTGGAGGGCAATTGCTATATCTTAGACCTGTCCATAT
GTATACCCAAGACTGTAACAGTGCTGGGCACACACAAGGTGATCAATAAACGGATGTTGATTGA
GTAA

hide sequence

RefSeq Acc Id:

XM_006528488 ⟹ XP_006528551

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	138,708,643 - 138,712,135 (+)	NCBI
GRCm38	X	139,807,894 - 139,811,386 (+)	NCBI

Sequence:

show sequence

AGACAGGAGATATCTGGTTTTCTAGATGCCTTCTTGAGCCTGCTTGTGGCCACCCACAGATACT
TGTAAGGAGGAAAGAAGTCAGCTTGCCAGAGACACTGTGAAATAAGGGATTAGAGGCTCGGATC
CAAGAAGCAAGAGCAGCAGCCAAACGACAAGCAAACAGGCTCCGAAGATACTTCTACTGAGAGG
TCTGCCATGGCCTCCCTTGGCGTCCAACTGGTGGGCTACATCCTAGGCCTTTTGGGGCTGTTAG
GCACATCCATTGCCATGCTGCTTCCCAACTGGCGAACGAGTTCCTATGTTGGTGCCAGCATTGT
GACGGCGGTTGGCTTTTCCAAGGGCCTCTGGATGGAGTGTGCGACACACAGCACAGGCATCACC
CAGTGCGATATCTACAGTACCCTTTTAGGACTTCCTGCTGACATCCAGGCTGCCCAGGCCATGA
TGGTGACGTCCAGTGCAATGTCCTCGCTGGCTTGTATTATCTCTGTGGTGGGCATGAGATGCAC
CGTGTTCTGCCAGGATTCTCGAGCTAAGGACAGAGTGGCTGTAGTGGGTGGAGTCTTTTTCATC
CTTGGTGGCATCCTGGGCTTTATCCCAGTTGCTTGGAATCTTCATGGCATCCTTCGGGACTTCT
ACTCGCCGCTGGTTCCTGACAGCATGAAATTTGAGATTGGAGAGGCTCTGTACTTGGGCATCAT
CTCAGCCCTGTTTTCTTTGGTAGCCGGAGTCATCCTTTGCTTTTCCTGCTCGCCCCAGGGCAAT
CGTACCAACTACTATGATGGCTACCAGGCCCAGCCTCTTGCCACTAGGAGCTCTCCAAGATCTG
CTCAACAGCCCAAAGCCAAGAGTGAGTTCAACTCATACAGCCTGACTGGAGAGGCAGCCCTACC
AGATACTTTAGACTTGATGGAAGACCAACCCATCAGGGTCTATGTCTCAGCACTACAGAGCCTC
TGAAAGACCACAGCACCAGAGAGGTCCTTTGTCACTTTTCACACTTGAGTCATCGCCCATCAGA
AGATACTCTCACAGGTATGCAAAGTCTCCAGTGTGGAACATCTGTGACCAAGGTGTTGTGTTCA
TGACCTGAGCAATTGGTGAACTTCTGCCTGGGATTGTGCTTGAGGTGGGAGAACGGAGACTGGT
TCCCTGTCCAACAGTTTTATTTCCACGGTCTTAAAATGCTCCATTTCTTCTGTGGTAGATGGGG
GTCATAAACCAGAGACATTTCCCCACCACCACCAGCTTAATATCACCAGCTTCAGAAGATCCCC
AGCGCACCTCATCAAAACTTCAGCACCGGCAAGAGAGGCCCATATGTGAGGTTTCCCTTAACAT
GCCTTTCCTATTTCCACCATATTACTTGTGTTCAAGCTGATATGCTGACCTGGAAGCCATTTCC
TTTTAACTAAGTCATCCCCATGCTTGGAGAACTTGCTCATTGAGCCTTCTCTGACCACTCCTTC
CTGTTCTTTCCTTTCCCTCCTCCAACTCCCAATATATAAATTGCCTAATCCTCATCATTCATAA
TTTTGATTGATAGTTTATAGTTCTTGTATGTGCATTTGTGTGTGACTCTATCCGTCTGTCTGTC
TGTGTGATCTCAAAAGTTCACTGTAAGTACTTGGAGGGCAATTGCTATATCTTAGACCTGTCCA
TATGTATACCCAAGACTGTAACAGTGCTGGGCACACACAAGGTGATCAATAAACGGATGTTGAT
TGAGTAA

hide sequence

RefSeq Acc Id:

XM_006528489 ⟹ XP_006528552

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	138,706,831 - 138,712,135 (+)	NCBI
GRCm38	X	139,806,081 - 139,811,386 (+)	NCBI

Sequence:

show sequence

GGAGTGTGAGCAGGTGAATGGCAATAGGTGAACCTTGAGAGGTCCCAGAGTGCAAACAGGCTTG
GACTTTATCCTTCGCCATTGGAATGTCCTAGAGGAGCAACTTGCTGTGAAAGCATGATGATCGG
AGTTCAGAGCTGCAAGAAGAATGTAAAAGAAGAGAAATGTGGGTGTGGAGGTTTTCTAGATGCC
TTCTTGAGCCTGCTTGTGGCCACCCACAGATACTTGTAAGGAGGAAAGAAGTCAGCTTGCCAGA
GACACTGTGAAATAAGGGATTAGAGGCTCGGATCCAAGAAGCAAGAGCAGCAGCCAAACGACAA
GCAAACAGGCTCCGAAGATACTTCTACTGAGAGGTCTGCCATGGCCTCCCTTGGCGTCCAACTG
GTGGGCTACATCCTAGGCCTTTTGGGGCTGTTAGGCACATCCATTGCCATGCTGCTTCCCAACT
GGCGAACGAGTTCCTATGTTGGTGCCAGCATTGTGACGGCGGTTGGCTTTTCCAAGGGCCTCTG
GATGGAGTGTGCGACACACAGCACAGGCATCACCCAGTGCGATATCTACAGTACCCTTTTAGGA
CTTCCTGCTGACATCCAGGCTGCCCAGGCCATGATGGTGACGTCCAGTGCAATGTCCTCGCTGG
CTTGTATTATCTCTGTGGTGGGCATGAGATGCACCGTGTTCTGCCAGGATTCTCGAGCTAAGGA
CAGAGTGGCTGTAGTGGGTGGAGTCTTTTTCATCCTTGGTGGCATCCTGGGCTTTATCCCAGTT
GCTTGGAATCTTCATGGCATCCTTCGGGACTTCTACTCGCCGCTGGTTCCTGACAGCATGAAAT
TTGAGATTGGAGAGGCTCTGTACTTGGGCATCATCTCAGCCCTGTTTTCTTTGGTAGCCGGAGT
CATCCTTTGCTTTTCCTGCTCGCCCCAGGGCAATCGTACCAACTACTATGATGGCTACCAGGCC
CAGCCTCTTGCCACTAGGAGCTCTCCAAGATCTGCTCAACAGCCCAAAGCCAAGAGTGAGTTCA
ACTCATACAGCCTGACTGGAGAGGCAGCCCTACCAGATACTTTAGACTTGATGGAAGACCAACC
CATCAGGGTCTATGTCTCAGCACTACAGAGCCTCTGAAAGACCACAGCACCAGAGAGGTCCTTT
GTCACTTTTCACACTTGAGTCATCGCCCATCAGAAGATACTCTCACAGGTATGCAAAGTCTCCA
GTGTGGAACATCTGTGACCAAGGTGTTGTGTTCATGACCTGAGCAATTGGTGAACTTCTGCCTG
GGATTGTGCTTGAGGTGGGAGAACGGAGACTGGTTCCCTGTCCAACAGTTTTATTTCCACGGTC
TTAAAATGCTCCATTTCTTCTGTGGTAGATGGGGGTCATAAACCAGAGACATTTCCCCACCACC
ACCAGCTTAATATCACCAGCTTCAGAAGATCCCCAGCGCACCTCATCAAAACTTCAGCACCGGC
AAGAGAGGCCCATATGTGAGGTTTCCCTTAACATGCCTTTCCTATTTCCACCATATTACTTGTG
TTCAAGCTGATATGCTGACCTGGAAGCCATTTCCTTTTAACTAAGTCATCCCCATGCTTGGAGA
ACTTGCTCATTGAGCCTTCTCTGACCACTCCTTCCTGTTCTTTCCTTTCCCTCCTCCAACTCCC
AATATATAAATTGCCTAATCCTCATCATTCATAATTTTGATTGATAGTTTATAGTTCTTGTATG
TGCATTTGTGTGTGACTCTATCCGTCTGTCTGTCTGTGTGATCTCAAAAGTTCACTGTAAGTAC
TTGGAGGGCAATTGCTATATCTTAGACCTGTCCATATGTATACCCAAGACTGTAACAGTGCTGG
GCACACACAAGGTGATCAATAAACGGATGTTGATTGAGTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001397350	(Get FASTA)	NCBI Sequence Viewer
	NP_057884	(Get FASTA)	NCBI Sequence Viewer
	XP_006528549	(Get FASTA)	NCBI Sequence Viewer
	XP_006528550	(Get FASTA)	NCBI Sequence Viewer
	XP_006528551	(Get FASTA)	NCBI Sequence Viewer
	XP_006528552	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC27079	(Get FASTA)	NCBI Sequence Viewer
	AAH15252	(Get FASTA)	NCBI Sequence Viewer
	AAH85494	(Get FASTA)	NCBI Sequence Viewer
	BAB23725	(Get FASTA)	NCBI Sequence Viewer
	EDL23917	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000054219
	ENSMUSP00000054219.4
	ENSMUSP00000121152.2
GenBank Protein	O88552	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_057884 ⟸ NM_016675

- UniProtKB:

O88552 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQC
DIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQDSRAKDRVAVVGGVFFILG
GILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCSPQGNRT
NYYDGYQAQPLATRSSPRSAQQPKAKSEFNSYSLTGYV

hide sequence

RefSeq Acc Id:

XP_006528549 ⟸ XM_006528486

- Peptide Label:

isoform X1

- Sequence:

show sequence

MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQC
DIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQDSRAKDRVAVVGGVFFILG
GILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCSPQGNRT
NYYDGYQAQPLATRSSPRSAQQPKAKSEFNSYSLTGEAALPDTLDLMEDQPIRVYVSALQSL

hide sequence

RefSeq Acc Id:

XP_006528550 ⟸ XM_006528487

- Peptide Label:

isoform X1

- Sequence:

show sequence

MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQC
DIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQDSRAKDRVAVVGGVFFILG
GILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCSPQGNRT
NYYDGYQAQPLATRSSPRSAQQPKAKSEFNSYSLTGEAALPDTLDLMEDQPIRVYVSALQSL

hide sequence

RefSeq Acc Id:

XP_006528552 ⟸ XM_006528489

- Peptide Label:

isoform X1

- Sequence:

show sequence

MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQC
DIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQDSRAKDRVAVVGGVFFILG
GILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCSPQGNRT
NYYDGYQAQPLATRSSPRSAQQPKAKSEFNSYSLTGEAALPDTLDLMEDQPIRVYVSALQSL

hide sequence

RefSeq Acc Id:

XP_006528551 ⟸ XM_006528488

- Peptide Label:

isoform X1

- Sequence:

show sequence

MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQC
DIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQDSRAKDRVAVVGGVFFILG
GILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCSPQGNRT
NYYDGYQAQPLATRSSPRSAQQPKAKSEFNSYSLTGEAALPDTLDLMEDQPIRVYVSALQSL

hide sequence

Ensembl Acc Id:

ENSMUSP00000054219 ⟸ ENSMUST00000054889

Ensembl Acc Id:

ENSMUSP00000134644 ⟸ ENSMUST00000172779

Ensembl Acc Id:

ENSMUSP00000121152 ⟸ ENSMUST00000135224

RefSeq Acc Id:	NP_001397350 ⟸ NM_001410421
- UniProtKB:	O88552 (UniProtKB/Swiss-Prot)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O88552-F1-model_v2	AlphaFold	O88552	1-230	view protein structure

Promoters

RGD ID:

6845562

Promoter ID:

MM_KWN:62054

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Kidney

Transcripts:

OTTMUST00000045069

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	X	136,340,501 - 136,341,001 (+)	MPROMDB

RGD ID:

6845563

Promoter ID:

MM_KWN:62055

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain, Kidney, Lung

Transcripts:

ENSMUST00000113021

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	X	136,342,301 - 136,343,227 (+)	MPROMDB

RGD ID:

13681490

Promoter ID:

EPDNEW_M24894

Type:

multiple initiation site

Name:

Cldn2_2

Description:

Mus musculus claudin 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M24895

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	X	139,800,805 - 139,800,865	EPDNEW

RGD ID:

13681492

Promoter ID:

EPDNEW_M24895

Type:

initiation region

Name:

Cldn2_1

Description:

Mus musculus claudin 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M24894

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	X	139,808,567 - 139,808,627	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1276110	AgrOrtholog
Ensembl Genes	ENSMUSG00000047230	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000054889	ENTREZGENE
	ENSMUST00000054889.4	UniProtKB/Swiss-Prot
	ENSMUST00000135224.2	UniProtKB/TrEMBL
Gene3D-CATH	1.20.140.150	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Claudin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Claudin2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Claudin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PMP22/EMP/MP20/Claudin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:12738	UniProtKB/Swiss-Prot
MGD	MGI:1276110	ENTREZGENE
NCBI Gene	12738	ENTREZGENE
PANTHER	CLAUDIN-2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR12002	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	PMP22_Claudin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Cldn2	PhenoGen
PRINTS	CLAUDIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CLAUDIN2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CLAUDIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A3KGB5_MOUSE	UniProtKB/TrEMBL
	CLD2_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

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Imported Annotations - KEGG (archival)

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