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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-anisomycin | decreases expression | ISO | RGD:1320126 | 6480464 | Anisomycin results in decreased expression of ATG4B protein | CTD | PMID:27629431 | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ATG4B mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of ATG4B mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATG4B mRNA | CTD | PMID:21570461, PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1309664 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ATG4B mRNA | CTD | PMID:33387578 | 2,4-dinitrotoluene | affects expression | ISO | RGD:1309664 | 6480464 | 2, 4-dinitrotoluene affects the expression of ATG4B mRNA | CTD | PMID:21346803 | 2-deoxy-D-glucose | multiple interactions | ISO | RGD:1320126 | 6480464 | [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of ATG4B mRNA | CTD | PMID:26079942 | 2-methylcholine | affects expression | ISO | RGD:1320126 | 6480464 | beta-methylcholine affects the expression of ATG4B mRNA | CTD | PMID:21179406 | 3-methyladenine | decreases expression | EXP | | 6480464 | 3-methyladenine results in decreased expression of ATG4B mRNA | CTD | PMID:21681844 | acrolein | multiple interactions | ISO | RGD:1320126 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ATG4B mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ATG4B mRNA | CTD | PMID:32699268 | alpha-pinene | multiple interactions | ISO | RGD:1320126 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ATG4B mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ATG4B mRNA | CTD | PMID:32699268 | aristolochic acid A | increases expression | ISO | RGD:1320126 | 6480464 | aristolochic acid I results in increased expression of ATG4B mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | RGD:1320126 | 6480464 | Arsenic affects the methylation of ATG4B gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1320126 | 6480464 | Arsenic affects the methylation of ATG4B gene | CTD | PMID:25304211 | arsenite(3-) | increases expression | ISO | RGD:1320126 | 6480464 | arsenite results in increased expression of ATG4B mRNA, arsenite results in increased expression of ATG4B protein | CTD | PMID:34929507 | atrazine | increases expression | EXP | | 6480464 | Atrazine results in increased expression of ATG4B mRNA | CTD | PMID:30360616 | atrazine | multiple interactions | EXP | | 6480464 | Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] | CTD | PMID:30360616 | cannabidiol | multiple interactions | EXP | | 6480464 | Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG4B mRNA] | CTD | PMID:30074247 | Cannabidivarin | multiple interactions | EXP | | 6480464 | cannabidivarin inhibits the reaction [DMD gene mutant form results in decreased expression of ATG4B mRNA] | CTD | PMID:30074247 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | clobetasol | increases expression | EXP | | 6480464 | Clobetasol results in increased expression of ATG4B mRNA | CTD | PMID:27462272 | cocaine | affects expression | ISO | RGD:1309664 | 6480464 | Cocaine affects the expression of ATG4B mRNA | CTD | PMID:20187946 | deoxynivalenol | increases expression | ISO | RGD:1320126 | 6480464 | deoxynivalenol results in increased expression of ATG4B mRNA | CTD | PMID:31863870 | dieldrin | increases response to substance | ISO | RGD:1320126 | 6480464 | ATG4B gene mutant form results in increased susceptibility to Dieldrin | CTD | PMID:32421776 | dinitrogen | decreases expression | ISO | RGD:1320126 | 6480464 | Nitrogen deficiency results in decreased expression of ATG4B protein | CTD | PMID:27629431 | doxorubicin | decreases expression | ISO | RGD:1320126 | 6480464 | Doxorubicin results in decreased expression of ATG4B mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | RGD:1320126 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ATG4B protein | CTD | PMID:23301498 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of ATG4B mRNA | CTD | PMID:30319688 | ivermectin | decreases expression | ISO | RGD:1320126 | 6480464 | Ivermectin results in decreased expression of ATG4B protein | CTD | PMID:32959892 | lycopene | multiple interactions | EXP | | 6480464 | Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] | CTD | PMID:30360616 | methotrexate | increases expression | ISO | RGD:1320126 | 6480464 | Methotrexate results in increased expression of ATG4B mRNA | CTD | PMID:21678067 | oxaliplatin | decreases expression | ISO | RGD:1309664 | 6480464 | oxaliplatin results in decreased expression of ATG4B mRNA | CTD | PMID:25729387 | oxaliplatin | multiple interactions | ISO | RGD:1309664 | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ATG4B mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | RGD:1320126 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ATG4B mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ATG4B mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | RGD:1320126 | 6480464 | Acetaminophen results in increased expression of ATG4B mRNA | CTD | PMID:29067470 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of ATG4B mRNA | CTD | PMID:21371552 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ATG4B mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of ATG4B mRNA | CTD | PMID:19136022 | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of ATG4B mRNA | CTD | PMID:19136022 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of ATG4B mRNA | CTD | PMID:23186747 | silicon dioxide | increases expression | ISO | RGD:1320126 | 6480464 | Silicon Dioxide results in increased expression of ATG4B mRNA | CTD | PMID:25351596 | sirolimus | increases expression | EXP | | 6480464 | Sirolimus results in increased expression of ATG4B mRNA | CTD | PMID:21681844 | sirolimus | multiple interactions | ISO | RGD:1320126 | 6480464 | Sirolimus inhibits the reaction [ATG4B protein results in increased expression of HK2 protein] more ... | CTD | PMID:36336208 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of ATG4B mRNA | CTD | PMID:30097599 | sodium arsenite | multiple interactions | EXP | | 6480464 | [sodium arsenite co-treated with Dietary Fats] results in increased expression of ATG4B mRNA | CTD | PMID:30097599 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of ATG4B protein | CTD | PMID:28918527 | tert-butyl hydroperoxide | decreases expression | ISO | RGD:1320126 | 6480464 | tert-Butylhydroperoxide results in decreased expression of ATG4B mRNA | CTD | PMID:15336504 | topotecan | multiple interactions | ISO | RGD:1309664 | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ATG4B mRNA | CTD | PMID:25729387 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of ATG4B mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | RGD:1320126 | 6480464 | Urethane results in increased expression of ATG4B mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | RGD:1320126 | 6480464 | Valproic Acid results in increased methylation of ATG4B gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:1320126 | 6480464 | Valproic Acid results in increased expression of ATG4B mRNA | CTD | PMID:29154799 | |