Zfp341 (zinc finger protein 341) - Rat Genome Database

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Gene: Zfp341 (zinc finger protein 341) Mus musculus
Analyze
Symbol: Zfp341
Name: zinc finger protein 341
RGD ID: 1558114
MGI Page MGI
Description: Predicted to enable DNA-binding transcription activator activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in central nervous system; female associated reproductive structure; ovary; tooth; and urethra of female. Human ortholog(s) of this gene implicated in hyper IgE recurrent infection syndrome 3. Orthologous to human ZNF341 (zinc finger protein 341).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC73471; Znf341
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392154,453,736 - 154,488,741 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2154,455,217 - 154,488,741 (+)EnsemblGRCm39 Ensembl
GRCm382154,611,816 - 154,646,821 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2154,613,297 - 154,646,821 (+)EnsemblGRCm38mm10GRCm38
MGSCv372154,439,104 - 154,472,553 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362154,304,809 - 154,338,258 (+)NCBIMGSCv36mm8
MGSCv362155,440,850 - 155,474,283 (+)NCBIMGSCv36mm8
Celera2160,541,217 - 160,566,229 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map276.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12466851   PMID:12520002   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18287559  
PMID:18799693   PMID:21677750   PMID:21873635   PMID:30973865   PMID:33473114   PMID:38355793  


Genomics

Comparative Map Data
Zfp341
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392154,453,736 - 154,488,741 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2154,455,217 - 154,488,741 (+)EnsemblGRCm39 Ensembl
GRCm382154,611,816 - 154,646,821 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2154,613,297 - 154,646,821 (+)EnsemblGRCm38mm10GRCm38
MGSCv372154,439,104 - 154,472,553 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362154,304,809 - 154,338,258 (+)NCBIMGSCv36mm8
MGSCv362155,440,850 - 155,474,283 (+)NCBIMGSCv36mm8
Celera2160,541,217 - 160,566,229 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map276.79NCBI
ZNF341
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382033,731,996 - 33,792,269 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2033,731,657 - 33,792,269 (+)EnsemblGRCh38hg38GRCh38
GRCh372032,319,802 - 32,380,075 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362031,783,469 - 31,843,736 (+)NCBINCBI36Build 36hg18NCBI36
Build 342031,783,468 - 31,843,736NCBI
Celera2029,072,525 - 29,132,795 (+)NCBICelera
Cytogenetic Map20q11.22NCBI
HuRef2029,105,231 - 29,164,875 (+)NCBIHuRef
CHM1_12032,221,188 - 32,281,398 (+)NCBICHM1_1
T2T-CHM13v2.02035,458,351 - 35,518,627 (+)NCBIT2T-CHM13v2.0
Zfp341
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83163,582,937 - 163,616,448 (+)NCBIGRCr8
mRatBN7.23143,122,699 - 143,156,250 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3143,119,093 - 143,156,249 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.03150,114,853 - 150,172,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3150,135,821 - 150,153,775 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.03156,511,320 - 156,544,251 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43145,086,839 - 145,105,846 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3141,855,266 - 141,888,862 (+)NCBICelera
Cytogenetic Map3q41NCBI
Znf341
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542227,537,917 - 27,583,711 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542227,537,293 - 27,583,713 (-)NCBIChiLan1.0ChiLan1.0
ZNF341
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22139,418,445 - 39,483,467 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12039,411,547 - 39,476,569 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02030,018,348 - 30,079,721 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12031,166,374 - 31,218,282 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2031,164,597 - 31,218,282 (+)Ensemblpanpan1.1panPan2
ZNF341
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12422,937,990 - 22,984,646 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2422,938,093 - 22,982,367 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2422,583,240 - 22,629,894 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02423,624,867 - 23,671,552 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2423,624,950 - 23,670,551 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12422,917,225 - 22,963,979 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02423,010,745 - 23,057,362 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02423,488,954 - 23,494,847 (+)NCBIUU_Cfam_GSD_1.0
UU_Cfam_GSD_1.02423,441,838 - 23,462,455 (+)NCBIUU_Cfam_GSD_1.0
Znf341
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640171,894,730 - 171,933,200 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365616,816,328 - 6,851,452 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365616,816,349 - 6,851,609 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF341
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1737,224,048 - 37,280,118 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11737,223,959 - 37,272,263 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21742,186,197 - 42,200,711 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF341
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1238,020,915 - 38,081,559 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl238,028,765 - 38,080,814 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605088,799,998 - 88,860,135 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf341
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248425,519,035 - 5,565,613 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248425,518,327 - 5,565,661 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1560
Count of miRNA genes:577
Interacting mature miRNAs:682
Transcripts:ENSMUST00000081926, ENSMUST00000109702, ENSMUST00000126421
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135699221169699361Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148238204181755017Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151778297181755017Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143773445169117924Mouse
13825247Agoc2_magouti coat color QTL 2 (mouse)2151841920159841920Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149236907181755017Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152329820181755017Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2149988902181755017Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135699221169699361Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
1558842Tailq2_mtail length QTL 2 (mouse)Not determined2151640941162737074Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135699221169699361Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
10412080Hylaq2_mHyperlocomotor activity related QTL 2 (mouse)Not determined2151640941164119146Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1357862Epfq1_mepididymal fat pad weight QTL 1 (mouse)Not determined2151640941162737074Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143773445165665019Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135699221169699361Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135432544173449616Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148664893181755017Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
1558867Gnf3_mgrowth and fatness 3 (mouse)Not determined2152699221169117924Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150212221181755017Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150212221181755017Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150212221181755017Mouse
11353826Bdln10_mbody length 10 (mouse)2140441482174441482Mouse
1558852Gnf2_mgrowth and fatness 2 (mouse)Not determined2152699221162197085Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
4141033Wg2d_mweight gain in high growth mice 2d (mouse)Not determined143773445160303008Mouse
1357772Scfq1_msubcutaneous fat pad weight QTL 1 (mouse)Not determined2151640941162737074Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132024159166024330Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
13524521Bodwtq2_mbody wweight QTL 2 (mouse)2153456184156386184Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse
13504830Bacsq1_mbaculum shape QTL 1 (mouse)2145716184161016184Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142428347176428450Mouse
12801461Intim1_mintima modifier 1 (mouse)2142428347176428450Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133144911167145058Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133144911167145058Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151709273174389124Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2138966600172966729Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000081926   ⟹   ENSMUSP00000080596
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2154,455,217 - 154,488,741 (+)Ensembl
GRCm38.p6 Ensembl2154,613,297 - 154,646,821 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109702   ⟹   ENSMUSP00000105324
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2154,455,290 - 154,488,698 (+)Ensembl
GRCm38.p6 Ensembl2154,613,370 - 154,646,778 (+)Ensembl
Ensembl Acc Id: ENSMUST00000126421   ⟹   ENSMUSP00000117383
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2154,455,276 - 154,488,698 (+)Ensembl
GRCm38.p6 Ensembl2154,613,356 - 154,646,778 (+)Ensembl
RefSeq Acc Id: NM_199304   ⟹   NP_955008
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392154,455,288 - 154,488,737 (+)NCBI
GRCm382154,613,368 - 154,646,817 (+)NCBI
MGSCv372154,439,104 - 154,472,553 (+)RGD
Celera2160,541,217 - 160,566,229 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036161505   ⟹   XP_036017398
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392154,455,267 - 154,488,741 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004940133
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392154,453,736 - 154,488,741 (+)NCBI
Sequence:
RefSeq Acc Id: XR_374456
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392154,453,736 - 154,487,628 (+)NCBI
GRCm382154,611,816 - 154,645,705 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_955008 (Get FASTA)   NCBI Sequence Viewer  
  XP_036017398 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH57098 (Get FASTA)   NCBI Sequence Viewer  
  EDL06090 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000080596
  ENSMUSP00000080596.7
  ENSMUSP00000105324.2
  ENSMUSP00000117383.2
RefSeq Acc Id: NP_955008   ⟸   NM_199304
- UniProtKB: Q6PGC9 (UniProtKB/TrEMBL),   A2AVM0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000117383   ⟸   ENSMUST00000126421
Ensembl Acc Id: ENSMUSP00000080596   ⟸   ENSMUST00000081926
Ensembl Acc Id: ENSMUSP00000105324   ⟸   ENSMUST00000109702
RefSeq Acc Id: XP_036017398   ⟸   XM_036161505
- Peptide Label: isoform X1
- UniProtKB: A2AVM0 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6PGC9-F1-model_v2 AlphaFold Q6PGC9 1-846 view protein structure

Promoters
RGD ID:6833126
Promoter ID:MM_KWN:32492
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000109702,   OTTMUST00000037818,   OTTMUST00000037819
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362154,438,791 - 154,439,291 (+)MPROMDB
RGD ID:6879320
Promoter ID:EPDNEW_M3111
Type:multiple initiation site
Name:Zfp341_1
Description:Mus musculus zinc finger protein 341 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382154,613,349 - 154,613,409EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2682937 AgrOrtholog
Ensembl Genes ENSMUSG00000059842 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000081926 ENTREZGENE
  ENSMUST00000081926.13 UniProtKB/TrEMBL
  ENSMUST00000109702.2 UniProtKB/TrEMBL
  ENSMUST00000126421.8 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report mmu:228807 UniProtKB/TrEMBL
MGD MGI:2682937 ENTREZGENE
NCBI Gene 228807 ENTREZGENE
PANTHER FI03704P-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
  zf-C2H2_6 UniProtKB/TrEMBL
PhenoGen Zfp341 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A2AVM0 ENTREZGENE, UniProtKB/TrEMBL
  D6REV2_MOUSE UniProtKB/TrEMBL
  Q6PGC9 ENTREZGENE, UniProtKB/TrEMBL