Phf6 (PHD finger protein 6) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Phf6 (PHD finger protein 6) Mus musculus
Analyze
Symbol: Phf6
Name: PHD finger protein 6
RGD ID: 1557948
MGI Page MGI
Description: Predicted to enable several functions, including histone deacetylase binding activity; phosphoprotein binding activity; and scaffold protein binding activity. Acts upstream of or within blastocyst hatching. Located in nucleus. Is expressed in several structures, including alimentary system; gonad; nervous system; sensory organ; and skin. Used to study Borjeson-Forssman-Lehmann syndrome. Human ortholog(s) of this gene implicated in Borjeson-Forssman-Lehmann syndrome; acute myeloid leukemia; and congestive heart failure. Orthologous to human PHF6 (PHD finger protein 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2700007B13Rik; 4931428F02Rik; mKIAA1823
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X52,001,091 - 52,045,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX52,001,143 - 52,045,820 (+)EnsemblGRCm39 Ensembl
GRCm38X52,912,214 - 52,956,961 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX52,912,266 - 52,956,943 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X50,265,443 - 50,310,120 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X49,156,893 - 49,201,570 (+)NCBIMGSCv36mm8
CeleraX40,338,044 - 40,382,845 (+)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX29.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal action potential  (IAGP)
abnormal auditory brainstem response  (IEA)
abnormal effector T cell number  (IAGP)
abnormal hematopoietic precursor cell morphology  (IAGP)
abnormal hematopoietic system physiology  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal object recognition memory  (IAGP)
abnormal social recognition  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal thymus cell ratio  (IAGP)
decreased adrenocorticotropin level  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating growth hormone level  (IAGP)
decreased circulating insulin-like growth factor I level  (IAGP)
decreased DN2 thymocyte number  (IAGP)
decreased double-negative T cell number  (IAGP)
decreased exploration in new environment  (IAGP)
decreased granulocyte monocyte progenitor cell number  (IAGP)
decreased growth hormone level  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased lean body mass  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased prolactin level  (IAGP)
decreased single cell response threshold  (IAGP)
decreased startle reflex  (IAGP)
decreased vertical activity  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
impaired contextual conditioning behavior  (IAGP)
increased B cell number  (IAGP)
increased bone marrow cell number  (IAGP)
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IAGP)
increased circulating interferon-alpha level  (IAGP)
increased common lymphocyte progenitor cell number  (IAGP)
increased hematopoietic precursor cell number  (IAGP)
increased hematopoietic stem cell number  (IAGP)
increased hematopoietic stem cell proliferation  (IAGP)
increased leukemia incidence  (IAGP)
increased leukocyte cell number  (IAGP)
increased megakaryocyte cell number  (IAGP)
increased plasmacytoid dendritic cell number  (IAGP)
increased pro-B cell number  (IAGP)
increased single cell response intensity  (IAGP)
increased susceptibility to pharmacologically induced seizures  (IAGP)
increased white adipose tissue amount  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
small pituitary gland  (IAGP)
thrombocytopenia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Full spectrum of clonal haematopoiesis-driver mutations in chronic heart failure and their associations with mortality. Kiefer KC, etal., ESC Heart Fail. 2021 Jun;8(3):1873-1884. doi: 10.1002/ehf2.13297. Epub 2021 Mar 28.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. Slattery ML, etal., Genes Chromosomes Cancer. 2017 Nov;56(11):769-787. doi: 10.1002/gcc.22481. Epub 2017 Jul 30.
11. Downregulation of PHF6 Inhibits Cell Proliferation and Migration in Hepatocellular Carcinoma. Yu Q, etal., Cancer Biother Radiopharm. 2019 May;34(4):245-251. doi: 10.1089/cbr.2018.2671. Epub 2019 Mar 19.
12. MicroRNA-214 suppresses cell proliferation and migration and cell metabolism by targeting PDK2 and PHF6 in hepatocellular carcinoma. Yu Q, etal., Cell Biol Int. 2019 Jul 22. doi: 10.1002/cbin.11207.
13. High expression of microRNA-500 is associated with poor prognosis in patients with acute myeloid leukemia receiving allogeneic hematopoietic stem cell transplantation. Zhang G, etal., Oncol Lett. 2019 Jun;17(6):5815-5820. doi: 10.3892/ol.2019.10250. Epub 2019 Apr 15.
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12415272   PMID:12477932   PMID:14610273   PMID:15328020   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:17698420   PMID:18799693   PMID:21267068   PMID:21642990   PMID:21677750   PMID:21873635   PMID:22174793   PMID:23791194   PMID:25556700   PMID:27626380   PMID:27869233  
PMID:28607179   PMID:30403997   PMID:30567843   PMID:30755422   PMID:30917958   PMID:31395598   PMID:32098917   PMID:32187544   PMID:32325033   PMID:32398456   PMID:32560809   PMID:32994169  
PMID:33772537   PMID:34161765   PMID:34321999   PMID:34465864   PMID:35091680   PMID:35449600   PMID:36551904   PMID:37118089   PMID:37393343   PMID:38429579  


Genomics

Comparative Map Data
Phf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X52,001,091 - 52,045,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX52,001,143 - 52,045,820 (+)EnsemblGRCm39 Ensembl
GRCm38X52,912,214 - 52,956,961 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX52,912,266 - 52,956,943 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X50,265,443 - 50,310,120 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X49,156,893 - 49,201,570 (+)NCBIMGSCv36mm8
CeleraX40,338,044 - 40,382,845 (+)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX29.28NCBI
PHF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X134,373,312 - 134,428,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX134,373,288 - 134,428,791 (+)EnsemblGRCh38hg38GRCh38
GRCh37X133,507,342 - 133,562,820 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X133,335,008 - 133,390,488 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X133,232,861 - 133,288,339NCBI
CeleraX133,894,183 - 133,949,652 (+)NCBICelera
Cytogenetic MapXq26.2NCBI
HuRefX122,905,958 - 122,961,468 (+)NCBIHuRef
CHM1_1X133,419,127 - 133,474,595 (+)NCBICHM1_1
T2T-CHM13v2.0X132,698,463 - 132,753,940 (+)NCBIT2T-CHM13v2.0
Phf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X137,576,214 - 137,619,297 (+)NCBIGRCr8
mRatBN7.2X132,656,658 - 132,699,720 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX132,656,672 - 132,699,127 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX134,816,738 - 134,859,802 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X138,399,577 - 138,442,639 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X135,965,278 - 136,008,343 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X158,698,353 - 158,739,855 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,698,356 - 158,739,838 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,268,653 - 158,288,109 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X152,890,577 - 152,930,657 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X153,324,996 - 153,366,506 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X139,850,136 - 139,890,670NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic MapXq36NCBI
Phf6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955473527,005 - 586,627 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955473527,005 - 586,589 (-)NCBIChiLan1.0ChiLan1.0
PHF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X133,808,035 - 133,864,349 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X133,811,627 - 133,867,947 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X123,521,956 - 123,578,256 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X133,822,260 - 133,877,452 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX133,822,260 - 133,873,990 (+)Ensemblpanpan1.1panPan2
PHF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X105,044,232 - 105,093,663 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX105,043,556 - 105,091,795 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX91,154,612 - 91,205,687 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X106,904,096 - 106,955,183 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX106,904,172 - 106,955,712 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X104,317,141 - 104,368,210 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X106,183,139 - 106,234,213 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X105,974,494 - 106,025,566 (+)NCBIUU_Cfam_GSD_1.0
Phf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X103,189,381 - 103,240,634 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936691716,697 - 768,016 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936691716,723 - 767,960 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX110,249,010 - 110,303,017 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X110,249,010 - 110,311,503 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X126,334,888 - 126,353,998 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PHF6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X109,531,700 - 109,595,136 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX109,531,726 - 109,593,854 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606547,136,942 - 47,193,137 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phf6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479714,081,302 - 14,128,487 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479714,081,381 - 14,140,180 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Phf6
1153 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2875
Count of miRNA genes:864
Interacting mature miRNAs:1188
Transcripts:ENSMUST00000078944, ENSMUST00000101587, ENSMUST00000154864, ENSMUST00000177780, ENSMUST00000179014
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208553Wght11_mweight 11 (mouse)X1186623959045360Mouse
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
27226750Femd9_mfemur midshaft diameter 9, 10 week (mouse)X3333746355845360Mouse
1301009Pbwg7_mpostnatal body weight growth 7 (mouse)Not determinedX3911371473113814Mouse
4141565Pbwg21_mpostnatal body weight growth 21 (mouse)Not determinedX3911371473113814Mouse
27226780Femd12_mfemur midshaft diameter 12, 16 week (mouse)X3466365356845360Mouse
13208557Lgth13_mbody length 13 (mouse)X1186623959045360Mouse
25314311Syncl3_msynaptonemal complex length 3 (mouse)X5198887789743606Mouse
1300853Aggr2_maggression 2 (mouse)Not determinedX4907116752259196Mouse
4142200Rtwq1_mreduced testis weight QTL 1 (mouse)Not determined4147706075477203Mouse
1300794Spha2_msperm head anomaly 2 (mouse)Not determinedX3992149886260137Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
1300702Fcsa4_mfemoral cross-sectional area 4 (mouse)Not determinedX4602744480027567Mouse
1301278Bdln1_mbody length 1 (mouse)Not determinedX4170210675702218Mouse
1301212Bw19_mbody weight QTL 19 (mouse)Not determinedX4637692052412327Mouse
1301351Obq6_mobesity QTL 6 (mouse)Not determinedX5077237570434751Mouse
13208567Bmiq12_mbody mass index QTL 12 (mouse)X3526365377043606Mouse

Markers in Region
AW549906  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X52,956,338 - 52,956,478UniSTSGRCm38
MGSCv37X50,309,515 - 50,309,655UniSTSGRCm37
CeleraX40,382,240 - 40,382,380UniSTS
Cytogenetic MapXA4UniSTS
Whitehead/MRC_RHX636.76UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001290546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_027642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK012211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK016480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX649621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ287261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000078944   ⟹   ENSMUSP00000077971
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX52,001,143 - 52,045,820 (+)Ensembl
GRCm38.p6 EnsemblX52,912,266 - 52,956,943 (+)Ensembl
Ensembl Acc Id: ENSMUST00000101587   ⟹   ENSMUSP00000110497
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX52,001,172 - 52,037,377 (+)Ensembl
GRCm38.p6 EnsemblX52,912,295 - 52,948,500 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154864   ⟹   ENSMUSP00000130358
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX52,001,172 - 52,044,842 (+)Ensembl
GRCm38.p6 EnsemblX52,912,295 - 52,955,965 (+)Ensembl
Ensembl Acc Id: ENSMUST00000177780
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX52,013,446 - 52,029,493 (+)Ensembl
GRCm38.p6 EnsemblX52,924,569 - 52,940,616 (+)Ensembl
Ensembl Acc Id: ENSMUST00000179014
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX52,013,448 - 52,029,512 (+)Ensembl
GRCm38.p6 EnsemblX52,924,571 - 52,940,635 (+)Ensembl
RefSeq Acc Id: NM_001290546   ⟹   NP_001277475
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X52,001,091 - 52,045,838 (+)NCBI
GRCm38X52,912,214 - 52,956,961 (+)NCBI
CeleraX40,337,992 - 40,382,863 (+)NCBI
Sequence:
RefSeq Acc Id: NM_027642   ⟹   NP_081918
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X52,001,091 - 52,045,838 (+)NCBI
GRCm38X52,912,214 - 52,956,961 (+)NCBI
MGSCv37X50,265,443 - 50,310,120 (+)RGD
CeleraX40,337,992 - 40,382,863 (+)NCBI
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NP_081918   ⟸   NM_027642
- Peptide Label: isoform 1
- UniProtKB: Q8BYT8 (UniProtKB/Swiss-Prot),   Q80T86 (UniProtKB/Swiss-Prot),   Q8C1B5 (UniProtKB/Swiss-Prot),   Q9D4J7 (UniProtKB/Swiss-Prot),   E9QAG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277475   ⟸   NM_001290546
- Peptide Label: isoform 2
- UniProtKB: Q9D4J7 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000110497   ⟸   ENSMUST00000101587
Ensembl Acc Id: ENSMUSP00000130358   ⟸   ENSMUST00000154864
Ensembl Acc Id: ENSMUSP00000077971   ⟸   ENSMUST00000078944
Protein Domains
PHD-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D4J7-F1-model_v2 AlphaFold Q9D4J7 1-364 view protein structure

Promoters
RGD ID:6846130
Promoter ID:MM_KWN:60300
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000101587,   NM_027642,   OTTMUST00000042252,   UC009TEN.1,   UC009TEO.1,   UC009TEQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X50,265,171 - 50,265,671 (+)MPROMDB
RGD ID:13680468
Promoter ID:EPDNEW_M24383
Type:initiation region
Name:Phf6_1
Description:Mus musculus PHD finger protein 6 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X52,912,311 - 52,912,371EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1918248 AgrOrtholog
Ensembl Genes ENSMUSG00000025626 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078944 ENTREZGENE
  ENSMUST00000078944.13 UniProtKB/Swiss-Prot
  ENSMUST00000101587.10 UniProtKB/TrEMBL
  ENSMUST00000154864 ENTREZGENE
  ENSMUST00000154864.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EPHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHD-type_Zinc_Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PHD UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:70998 UniProtKB/Swiss-Prot
MGD MGI:1918248 ENTREZGENE
NCBI Gene 70998 ENTREZGENE
PANTHER PHD FINGER PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHD FINGER PROTEIN 6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-HC5HC2H UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Phf6 PhenoGen
PROSITE EPHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PHD UniProtKB/Swiss-Prot
UniProt E9QAG2 ENTREZGENE, UniProtKB/TrEMBL
  PHF6_MOUSE UniProtKB/Swiss-Prot
  Q3UXP1_MOUSE UniProtKB/TrEMBL
  Q80T86 ENTREZGENE
  Q8BVK8_MOUSE UniProtKB/TrEMBL
  Q8BYT8 ENTREZGENE
  Q8C1B5 ENTREZGENE
  Q9CSQ5_MOUSE UniProtKB/TrEMBL
  Q9D4J7 ENTREZGENE
UniProt Secondary Q80T86 UniProtKB/Swiss-Prot
  Q8BYT8 UniProtKB/Swiss-Prot
  Q8C1B5 UniProtKB/Swiss-Prot