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Gene: Magee2 (MAGE family member E2) Mus musculus

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Symbol:

Magee2

Name:

MAGE family member E2

RGD ID:

1557922

MGI Page

MGI

Description:

Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including brain; dorsal root ganglion; egg cylinder; liver; and reproductive system. Orthologous to human MAGEE2 (MAGE family member E2).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

9630059J11Rik; BB131182; Mage-e; Mage-e2; melanoma antigen, family E, 2; melanoma-associated antigen E2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MAGEE2 (MAGE family member E2)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Magee2 (MAGE family member E2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Magee2 (MAGE family member E2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MAGEE2 (MAGE family member E2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MAGEE2 (MAGE family member E2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Magee2 (MAGE family member E2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MAGEE2 (MAGE family member E2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MAGEE2 (MAGE family member E2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Magee2 (MAGE family member E2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MAGEE2 (MAGE family member E2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Magee2 (MAGE family member E2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	MAGE	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	NSE3	Alliance	DIOPT (Hieranoid\|PANTHER)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	103,898,558 - 103,900,873 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	103,898,558 - 103,900,873 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	104,854,952 - 104,857,267 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	104,854,952 - 104,857,267 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	102,050,291 - 102,052,606 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	101,057,671 - 101,059,875 (-)	NCBI		MGSCv36	mm8
Celera	X	91,728,756 - 91,731,078 (-)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	46.77	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

factor VIII deficiency (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

6-propyl-2-thiouracil (ISO)

aflatoxin B1 (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

endosulfan (ISO)

epoxiconazole (EXP)

ivermectin (ISO)

pentanal (ISO)

sodium arsenite (EXP)

tungsten (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IBA)

Molecular Function

molecular_function (ND)

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal retrosplenial granular cortex morphology (IAGP)

increased anterior commissure size (IAGP)

increased brain size (IAGP)

increased hippocampal fimbria size (IAGP)

increased pons size (IAGP)

increased primary motor cortex size (IAGP)

increased retrosplenial granular cortex size (IAGP)

increased superior colliculus size (IAGP)

megacephaly (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11454705	PMID:12466851	PMID:12477932	PMID:16141072	PMID:16141073	PMID:21267068	PMID:21873635	PMID:27720483
PMID:31143371	PMID:34464968	PMID:38355793

Genomics

Comparative Map Data

Magee2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	103,898,558 - 103,900,873 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	103,898,558 - 103,900,873 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	104,854,952 - 104,857,267 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	104,854,952 - 104,857,267 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	102,050,291 - 102,052,606 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	101,057,671 - 101,059,875 (-)	NCBI		MGSCv36	mm8
Celera	X	91,728,756 - 91,731,078 (-)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	46.77	NCBI

MAGEE2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	75,782,987 - 75,785,254 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	75,782,987 - 75,785,254 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	75,002,822 - 75,005,089 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	74,919,548 - 74,921,796 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	74,785,843 - 74,788,092	NCBI
Celera	X	75,286,151 - 75,288,407 (-)	NCBI		Celera
Cytogenetic Map	X	q13.3	NCBI
HuRef	X	68,636,741 - 68,638,996 (-)	NCBI		HuRef
CHM1_1	X	74,895,669 - 74,897,925 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	74,216,673 - 74,218,940 (-)	NCBI		T2T-CHM13v2.0

Magee2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	73,951,433 - 74,010,525 (+)	NCBI		GRCr8
mRatBN7.2	X	69,885,751 - 69,944,824 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	69,942,533 - 69,944,657 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	71,451,596 - 71,453,720 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	74,951,881 - 74,954,005 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	72,511,457 - 72,513,581 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	75,737,684 - 75,795,206 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	75,792,931 - 75,795,055 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	76,537,710 - 76,595,148 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	92,944,523 - 92,946,647 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	71,286,892 - 71,289,016 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

Magee2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955562	1,804,437 - 1,807,099 (-)	NCBI	ChiLan1.0	ChiLan1.0

MAGEE2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	75,429,205 - 75,431,629 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	75,432,855 - 75,435,242 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	65,030,659 - 65,033,059 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	75,141,998 - 75,144,309 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	75,142,500 - 75,144,068 (-)	Ensembl	panpan1.1		panPan2

MAGEE2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	58,877,193 - 58,879,518 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	58,877,722 - 58,879,293 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	X	60,109,448 - 60,111,767 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	60,109,982 - 60,111,553 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	57,797,220 - 57,799,539 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	59,417,054 - 59,419,373 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	59,015,922 - 59,018,241 (-)	NCBI		UU_Cfam_GSD_1.0

Magee2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	43,256,515 - 43,258,796 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936683	1,689,463 - 1,691,034 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936683	1,688,981 - 1,691,250 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAGEE2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	60,709,534 - 60,711,829 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	60,707,490 - 60,711,883 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MAGEE2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	65,244,718 - 65,247,582 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	65,245,359 - 65,246,930 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666067	16,359,398 - 16,362,396 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Magee2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624836	5,040,440 - 5,042,334 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Magee2
57 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	185
Count of miRNA genes:	166
Interacting mature miRNAs:	173
Transcripts:	ENSMUST00000033575
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4141630	Gct6_m	granulosa cell tumorigenesis 6 (mouse)			Not determined			47179121	129764756	Mouse
13208552	Wght12_m	weight 12 (mouse)					X	94043606	149782996	Mouse
4141803	Lmr30_m	leishmaniasis resistance 30 (mouse)			Not determined			85062606	119062720	Mouse
13208556	Lgth14_m	body length 14 (mouse)					X	94043606	149782996	Mouse
13824980	Ferq1_m	genetic fertility QTL 1 (mouse)					X	54045360	148782996	Mouse
11075102	Modc2_m	modifier of Odc2 (mouse)					X	80189914	114190059	Mouse
1357500	Mdmsc6_m	modifier of muscularity 6 (mouse)			Not determined		X	75306671	109306758	Mouse
1357823	Spha3_m	sperm head anomaly 3 (mouse)			Not determined		X	102055848	162758941	Mouse
1357433	Dbts2_m	diabetes 2 (mouse)			Not determined		X	7226295	150107038	Mouse
4141665	Mhysq2_m	male hybrid sterility QTL 2 (mouse)			Not determined			71453852	139203212	Mouse

Markers in Region

BB131182

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	104,854,977 - 104,855,099	UniSTS	GRCm38
MGSCv37	X	102,050,316 - 102,050,438	UniSTS	GRCm37
Celera	X	91,728,781 - 91,728,903	UniSTS
Cytogenetic Map	X	C3	UniSTS

UniSTS:238063

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	104,855,724 - 104,855,818	UniSTS	GRCm38
MGSCv37	X	102,051,063 - 102,051,157	UniSTS	GRCm37
Celera	X	91,729,535 - 91,729,629	UniSTS
Cytogenetic Map	X	C3	UniSTS

UniSTS:493381

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	104,855,472 - 104,857,118	UniSTS	GRCm38
MGSCv37	X	102,050,811 - 102,052,457	UniSTS	GRCm37
Celera	X	91,729,283 - 91,730,929	UniSTS
Cytogenetic Map	X	C3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AH010759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK036343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK134670	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL663095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC094361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC132640	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC138210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000033575 ⟹ ENSMUSP00000033575

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	X	103,898,558 - 103,900,873 (-)	Ensembl
GRCm38.p6 Ensembl	X	104,854,952 - 104,857,267 (-)	Ensembl

RefSeq Acc Id:

NM_053206 ⟹ NP_444436

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	103,898,558 - 103,900,873 (-)	NCBI
GRCm38	X	104,854,952 - 104,857,267 (-)	ENTREZGENE
MGSCv37	X	102,050,291 - 102,052,606 (-)	RGD
Celera	X	91,728,756 - 91,731,078 (-)	RGD
cM Map	X		ENTREZGENE

Sequence:

show sequence

GAGTGCGCCTGCGTAGGATGCGGCAAAGCTAGGTGCTCTTAGGCTTTCCTTCATTGCTGGCTAC
TGCTTTTGTAAAAGGATCGCCTGTCTCGCCAGCTCTCACTTTCGAACCGCACAGCTCCTGAGTA
TCAGGCTTCGGCTCTGAGCTGAGCTGCCAACACACCTCAGATCCTCCCTGCGACGGATCGCTGA
CCTCCGCGTTCGCGTTCCTGTCTCCTGGAACCATGTCTCTGGTAAGCCAGAATGCGCGCCAAAG
CAGCGCAGAGACTACCGCCGATTACAGCAACAGCCAGGGTGAAATGCAGGCTACTAATGCCTCC
GGGCCTGCCACCTCCATGCTAGCCCTCGAAGCTCCCCAGGGCCCTGAGATTCCAAACGATCCAC
AGGGAGCCAGCGCTTCCCAGGCTGTGCGGGACCCGAGTGACATCGAGGTTCTCATCGACGAGCA
GTCCCGACGTTTGGGGGCGCTCAGGGTCCACGACCCTCTTGAAGAGAGGTCGGTTGCTTTAGTG
AATTTCATGCGCATGAAAAGCCAAAATGAGGGGTCTATCCGACAGTCAGAAATGCTGGAGTTTC
TCAAAGAATACTCAGATCAGTTCCCTGAGATACTCAGACGAGCCTCAGCTCATCTGGATCGGGT
CTTTGGGTTGAATCTGAGAGTCCTTGATCCTCAGATGGACACTTACAACCTAATCAGCAAACCA
GGTCCCCAGACCACTGAACGGCTAGCAGAGACCCTGGACATACCAAAAGCGGGTCTCCTGGCCT
TGGTCCTAGGCCATATTCTCTTGAATGGCAACCGGGCAAGAGAGGCCTCCATTTGGGACCTGCT
GTTAAAGGTGGATGTGATAGATGGGTCTCAGAGGATCAACAACCAGTTTGGGAACACAAGAAAC
CTCCTTACTATTGACTTTGTCCATATGCGATTTTTGGAGTACTGGCCAGTATATGGCACTAATC
CCCTTGAATTTGAGTTCCTGTGGGGCTCTAGAGCTCACAGTGAAATCACAAAGATGGAAGCCCT
GAAGTTTGTAGCAGAGGCCCATGATGAAGAACCCTGGAGCTGGCCAGAAGAATATAACAAAGCT
CTGGAAGCTGACAAAGCCAAAGAGAGAAGCCAGGCTGCTGGCTTAGAGTTCTGGTCAGAGGACA
CTATGAATGATAAAGCAAATGAATTGGTCCAGTTGGCCATTGGTGTCACTGAGGAGTTGCTGCC
TATCCATCAGGATGAGCTATTTGCTAATACTGGCAAAGAATTCCAGGATGTGTTCCCAAATATC
CTCAGCAGAGCCACTCTAATCCTTGATCTGTTTTATGGGTTCTCTCTGATTGAGGTTGATACCA
GTGAGCACATCTACCTCCTTGTCCCCCAACCAGAATCAGAAGAAGAACAAGTAATGCTAGAGAG
CCTGGGCAGACCCACCCAAGAATACTTGATGCCAATCCTGGGTTTGATCTTCCTGATGGGCAAC
CGTGTCAAAGAGGCCAAGATCTGGAACTTACTCCAGAGATTCAGTGTTGATGTAGGGAGGAAAC
ATGCCATCACCTGTAAGCTAATGAGGCAACGCTACCTAGAATGCAGGCCGCTCTCCTACTCGAA
TCCAGTTGAATACGAGCTGCTCTGGGGTCCTCGGGCTCACCATGAAATCACCAAAATGAAAGCC
TTGGAATATATGGCTAGGTTCTATGGAAAACAGCCACAGGACTGGCCAGAGCAATACAGGGAGG
CTGTGGAAGATGAGGAGGCCAGGGCCAGGTCTGAGGCAACAGCCATGTTCTTCTTCGGTTCCAT
CTGACGTTGGACATTTCACTTTAGTTGAGTGACATCTGTTAAAAGGGCATTTGGGAAATGGACA
CTAGGGTCCTAAATCAAAAGTTGAGAGGGTTGTGGGAAAGAGTACACCTTGTGTTTATTGCATT
CCAATTCTAATAGCATTTCTTCCCTTCTAATATCCTCTTTAATTGTCTTCATGATCAGTGTTTA
TAAGTGAAATTGCTCATTTTCTTTTCCTGTCTTGTTTCAGTATAAGAGTTCAGATAGCTGTATA
AAATGTGTTGGTAATATTTACATATTTGAACAACCAGTAAAATAAGCTAAATAACAGTAATAAT
ACACATGTGTGTGCGCGCGAGCACACACACACACACACACACACACACACACACACACACACCC
CAAACACAAAGTCATGTGGTTGCTCTCCTTTTGAGTCTATTGTTGTGTTAACAAACTAACAAAA
ATTAAAGACTGTTACTTCCCTGTATTTAATTTGCGGTTGCACAGTGTAGTAAAAAATAAAAGTA
TAATGAATTAGAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_444436	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH94361	(Get FASTA)	NCBI Sequence Viewer
	AAI32641	(Get FASTA)	NCBI Sequence Viewer
	AAI38211	(Get FASTA)	NCBI Sequence Viewer
	AAK01210	(Get FASTA)	NCBI Sequence Viewer
	AAK01211	(Get FASTA)	NCBI Sequence Viewer
	BAC29390	(Get FASTA)	NCBI Sequence Viewer
	EDL14078	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000033575
	ENSMUSP00000033575.6

RefSeq Acc Id:

NP_444436 ⟸ NM_053206

- UniProtKB:

Q52KG3 (UniProtKB/TrEMBL), Q8CBC3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSLVSQNARQSSAETTADYSNSQGEMQATNASGPATSMLALEAPQGPEIPNDPQGASASQAVRD
PSDIEVLIDEQSRRLGALRVHDPLEERSVALVNFMRMKSQNEGSIRQSEMLEFLKEYSDQFPEI
LRRASAHLDRVFGLNLRVLDPQMDTYNLISKPGPQTTERLAETLDIPKAGLLALVLGHILLNGN
RAREASIWDLLLKVDVIDGSQRINNQFGNTRNLLTIDFVHMRFLEYWPVYGTNPLEFEFLWGSR
AHSEITKMEALKFVAEAHDEEPWSWPEEYNKALEADKAKERSQAAGLEFWSEDTMNDKANELVQ
LAIGVTEELLPIHQDELFANTGKEFQDVFPNILSRATLILDLFYGFSLIEVDTSEHIYLLVPQP
ESEEEQVMLESLGRPTQEYLMPILGLIFLMGNRVKEAKIWNLLQRFSVDVGRKHAITCKLMRQR
YLECRPLSYSNPVEYELLWGPRAHHEITKMKALEYMARFYGKQPQDWPEQYREAVEDEEARARS
EATAMFFFGSI

hide sequence

Ensembl Acc Id:

ENSMUSP00000033575 ⟸ ENSMUST00000033575

Protein Domains

MAGE

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q52KG3-F1-model_v2	AlphaFold	Q52KG3	1-523	view protein structure

Promoters

RGD ID:

6845931

Promoter ID:

MM_KWN:61472

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain, ES_Cell

Transcripts:

NM_053206

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	X	102,052,226 - 102,052,726 (-)	MPROMDB

RGD ID:

13681156

Promoter ID:

EPDNEW_M24727

Type:

initiation region

Name:

Magee2_1

Description:

Mus musculus melanoma antigen, family E, 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	X	104,857,215 - 104,857,275	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2148316	AgrOrtholog
Ensembl Genes	ENSMUSG00000031224	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000033575	ENTREZGENE
	ENSMUST00000033575.7	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.1200	UniProtKB/TrEMBL
	1.10.10.1210	UniProtKB/TrEMBL
InterPro	MAGE	UniProtKB/TrEMBL
	MAGE	UniProtKB/TrEMBL
	MAGE_WH1	UniProtKB/TrEMBL
	MAGE_WH2	UniProtKB/TrEMBL
KEGG Report	mmu:272790	UniProtKB/TrEMBL
MGD	MGI:2148316	ENTREZGENE
NCBI Gene	Magee2	ENTREZGENE
PANTHER	MELANOMA-ASSOCIATED ANTIGEN E2	UniProtKB/TrEMBL
	PTHR11736	UniProtKB/TrEMBL
Pfam	MAGE	UniProtKB/TrEMBL
PhenoGen	Magee2	PhenoGen
PROSITE	MAGE	UniProtKB/TrEMBL
SMART	MAGE	UniProtKB/TrEMBL
UniProt	Q52KG3	ENTREZGENE, UniProtKB/TrEMBL
	Q8CBC3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-08-21	Magee2	MAGE family member E2	Magee2	melanoma antigen, family E, 2	Symbol and/or name change	5135510	APPROVED
2024-08-21	Magee2	melanoma antigen, family E, 2	Magee2	MAGE family member E2	Symbol and/or name change	5135510	APPROVED
2020-09-01	Magee2	MAGE family member E2	Magee2	melanoma antigen, family E, 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Mammalian Phenotype