Ptx3 (pentraxin related gene) - Rat Genome Database

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Gene: Ptx3 (pentraxin related gene) Mus musculus
Analyze
Symbol: Ptx3
Name: pentraxin related gene
RGD ID: 1557644
MGI Page MGI
Description: Enables (1->3)-beta-D-glucan binding activity. Acts upstream of or within several processes, including opsonization; ovarian cumulus expansion; and positive regulation of nitric oxide biosynthetic process. Located in extracellular matrix. Is expressed in dentate gyrus subgranular zone and inner ear. Human ortholog(s) of this gene implicated in cystic fibrosis and invasive aspergillosis. Orthologous to human PTX3 (pentraxin 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI607804; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin-related protein PTX3; TSG-1; TSG-14; tumor necrosis factor-inducible gene 14 protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39366,127,308 - 66,133,227 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl366,127,331 - 66,133,226 (+)EnsemblGRCm39 Ensembl
GRCm38366,219,887 - 66,225,806 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl366,219,910 - 66,225,805 (+)EnsemblGRCm38mm10GRCm38
MGSCv37366,023,809 - 66,029,728 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36366,307,812 - 66,313,734 (+)NCBIMGSCv36mm8
Celera366,363,920 - 66,369,839 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(E)-thiamethoxam  (EXP)
(S)-nicotine  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-diaminotoluene  (EXP)
2-naphthylamine  (ISO)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methylcholanthrene  (EXP)
3-Nitrobenzanthrone  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
belinostat  (ISO)
benzalkonium chloride  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bortezomib  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
chlordecone  (EXP)
chromium(6+)  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
Cuprizon  (ISO)
curcumin  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
Didecyldimethylammonium  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
fenamidone  (EXP)
fluoranthene  (EXP)
fonofos  (ISO)
furan  (ISO)
gentamycin  (ISO)
hexadecanoic acid  (ISO)
hydrogen cyanide  (EXP)
iron atom  (ISO)
iron(0)  (ISO)
isoflavones  (ISO)
isoprenaline  (EXP)
ketoconazole  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
microcystin-LR  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
naphthalene  (EXP)
nickel atom  (EXP,ISO)
nicotine  (ISO)
nitrates  (ISO)
ozone  (EXP)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
PD 0325901  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
potassium chromate  (ISO)
potassium cyanide  (EXP)
progesterone  (ISO)
propanal  (ISO)
protein kinase inhibitor  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 203580  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
Tanshinone I  (ISO)
terbufos  (ISO)
thapsigargin  (ISO)
thiamethoxam  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
trans-caffeic acid  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (EXP,ISO)
vincaleukoblastine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Source of Circulating Pentraxin 3 in Septic Shock Patients. Albert Vega C, etal., Front Immunol. 2019 Jan 4;9:3048. doi: 10.3389/fimmu.2018.03048. eCollection 2018.
2. Genetic variation in PTX3 and plasma levels associated with hepatocellular carcinoma in patients with HCV. Carmo RF, etal., J Viral Hepat. 2016 Feb;23(2):116-22. doi: 10.1111/jvh.12472. Epub 2015 Sep 24.
3. Significant elevation of plasma pentraxin 3 in patients with pelvic inflammatory disease. Chang CC, etal., Clin Chem Lab Med. 2011 Oct;49(10):1655-60. doi: 10.1515/CCLM.2011.650. Epub 2011 Jun 17.
4. PTX3 genetic variations affect the risk of Pseudomonas aeruginosa airway colonization in cystic fibrosis patients. Chiarini M, etal., Genes Immun. 2010 Dec;11(8):665-70. doi: 10.1038/gene.2010.41. Epub 2010 Oct 7.
5. Pentraxin-3 as a marker of disease severity and risk of death in patients with necrotizing soft tissue infections: a nationwide, prospective, observational study. Hansen MB, etal., Crit Care. 2016 Feb 15;20:40. doi: 10.1186/s13054-016-1210-z.
6. Pentraxin 3 Gene Polymorphisms and Pulmonary Aspergillosis in Chronic Obstructive Pulmonary Disease Patients. He Q, etal., Clin Infect Dis. 2018 Jan 6;66(2):261-267. doi: 10.1093/cid/cix749.
7. Polymorphisms in Receptors Involved in Opsonic and Nonopsonic Phagocytosis, and Correlation with Risk of Infection in Oncohematology Patients. Herrero-Sánchez MC, etal., Infect Immun. 2018 Nov 20;86(12). pii: IAI.00709-18. doi: 10.1128/IAI.00709-18. Print 2018 Dec.
8. Pentraxin 3 levels in bronchoalveolar lavage fluid of lung transplant recipients with invasive aspergillosis. Kabbani D, etal., J Heart Lung Transplant. 2017 Sep;36(9):973-979. doi: 10.1016/j.healun.2017.04.007. Epub 2017 Apr 19.
9. Pentraxin 3 in bronchoalveolar lavage fluid and plasma in non-neutropenic patients with pulmonary aspergillosis. Li H, etal., Clin Microbiol Infect. 2019 Apr;25(4):504-510. doi: 10.1016/j.cmi.2018.06.015. Epub 2018 Jun 28.
10. MGDs mouse GO annotations MGD data from the GO Consortium
11. MGD IEA MGD IEA
12. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. Pentraxin-3: A new parameter in predicting the severity of diabetic foot infection? Ozer Balin S, etal., Int Wound J. 2019 Jun;16(3):659-664. doi: 10.1111/iwj.13075. Epub 2019 Feb 15.
14. Mouse MP Annotation Import Pipeline RGD automated import pipeline
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7592730   PMID:7679696   PMID:8634434   PMID:8889548   PMID:9407058   PMID:10349636   PMID:10585298   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11404378   PMID:11483299  
PMID:11812828   PMID:12000727   PMID:12040004   PMID:12432394   PMID:12477932   PMID:12763682   PMID:14726497   PMID:14998931   PMID:15489334   PMID:15894273   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:16697676   PMID:16769728   PMID:16783635   PMID:16840729   PMID:17389238   PMID:17538075   PMID:17675295   PMID:18218986   PMID:18268142   PMID:18292565   PMID:18703503  
PMID:19286566   PMID:19667236   PMID:19734205   PMID:19921147   PMID:20208538   PMID:20829368   PMID:20920344   PMID:21308776   PMID:21388349   PMID:21441447   PMID:21619930   PMID:21637713  
PMID:21873635   PMID:22019014   PMID:22173877   PMID:22267482   PMID:22280990   PMID:22383462   PMID:22384161   PMID:22425349   PMID:22732935   PMID:22895517   PMID:23217261   PMID:23325083  
PMID:23372656   PMID:23424081   PMID:23442541   PMID:23863905   PMID:24006456   PMID:24145127   PMID:24154525   PMID:24307735   PMID:24346689   PMID:24470395   PMID:24664887   PMID:24745336  
PMID:25001601   PMID:25049357   PMID:25227610   PMID:25342475   PMID:25679762   PMID:25695775   PMID:25747934   PMID:25774777   PMID:25786110   PMID:25964372   PMID:26267536   PMID:26470821  
PMID:26576501   PMID:26578407   PMID:26650391   PMID:26763449   PMID:26976330   PMID:27301880   PMID:27567326   PMID:27621420   PMID:27659908   PMID:28360101   PMID:28770376   PMID:28850023  
PMID:28864415   PMID:28965650   PMID:29492210   PMID:29556234   PMID:29741292   PMID:29779941   PMID:30105036   PMID:30315331   PMID:30319631   PMID:30396995   PMID:30718300   PMID:30859179  
PMID:31019517   PMID:31209269   PMID:31957804   PMID:32041791   PMID:32436939   PMID:33222690   PMID:33326783   PMID:33584725   PMID:33679758   PMID:33953334   PMID:34093560   PMID:34305885  
PMID:34321664   PMID:34411594   PMID:34653679   PMID:34906547   PMID:35175194   PMID:35194044   PMID:35522573   PMID:35687213   PMID:36012705   PMID:36530573   PMID:37010796   PMID:37087632  
PMID:37222419   PMID:37542771   PMID:37922722   PMID:38068970   PMID:38243273   PMID:38457930  


Genomics

Comparative Map Data
Ptx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39366,127,308 - 66,133,227 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl366,127,331 - 66,133,226 (+)EnsemblGRCm39 Ensembl
GRCm38366,219,887 - 66,225,806 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl366,219,910 - 66,225,805 (+)EnsemblGRCm38mm10GRCm38
MGSCv37366,023,809 - 66,029,728 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36366,307,812 - 66,313,734 (+)NCBIMGSCv36mm8
Celera366,363,920 - 66,369,839 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.25NCBI
PTX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383157,436,850 - 157,443,633 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3157,436,850 - 157,443,633 (+)EnsemblGRCh38hg38GRCh38
GRCh373157,154,639 - 157,161,422 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363158,637,301 - 158,644,071 (+)NCBINCBI36Build 36hg18NCBI36
Build 343158,637,308 - 158,644,078NCBI
Celera3155,578,255 - 155,585,092 (+)NCBICelera
Cytogenetic Map3q25.32NCBI
HuRef3154,550,694 - 154,557,531 (+)NCBIHuRef
CHM1_13157,117,566 - 157,124,403 (+)NCBICHM1_1
T2T-CHM13v2.03160,211,418 - 160,218,201 (+)NCBIT2T-CHM13v2.0
Ptx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82152,797,563 - 152,803,372 (+)NCBIGRCr8
mRatBN7.22150,487,513 - 150,493,323 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2150,487,513 - 150,493,323 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2157,593,206 - 157,599,014 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02155,643,731 - 155,649,539 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02150,276,449 - 150,282,257 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02158,097,843 - 158,103,653 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2158,097,843 - 158,103,653 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02177,457,263 - 177,463,073 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42156,089,917 - 156,095,726 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2144,894,946 - 144,900,755 (+)NCBICelera
Cytogenetic Map2q31NCBI
Ptx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554488,366,925 - 8,372,411 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554488,366,795 - 8,373,010 (+)NCBIChiLan1.0ChiLan1.0
PTX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22155,347,564 - 155,354,440 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13155,347,508 - 155,359,171 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03154,485,470 - 154,492,293 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13162,537,440 - 162,544,263 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3162,537,577 - 162,543,652 (+)Ensemblpanpan1.1panPan2
PTX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12350,952,835 - 50,958,607 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2350,952,885 - 50,958,167 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2350,825,322 - 50,831,079 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02351,586,874 - 51,592,673 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12351,169,291 - 51,175,068 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02351,222,224 - 51,228,028 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02351,507,584 - 51,513,394 (+)NCBIUU_Cfam_GSD_1.0
Ptx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560285,424,779 - 85,430,719 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365194,303,464 - 4,309,173 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365194,303,549 - 4,309,143 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1397,273,594 - 97,279,569 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11397,273,594 - 97,279,570 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213105,440,917 - 105,446,892 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11533,320,592 - 33,327,236 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1533,321,208 - 33,327,268 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660415,897,822 - 5,904,486 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473035,125,605 - 35,131,367 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473035,125,536 - 35,131,645 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptx3
194 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:374
Count of miRNA genes:282
Interacting mature miRNAs:342
Transcripts:ENSMUST00000029421, ENSMUST00000182521
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
10412073Ssen2_msuseptibility to Sendai virus 2 (mouse)Not determined33353546567535615Mouse
9587784Afw13_mabdominal fat weight QTL 13 (mouse)Not determined33375204567752228Mouse
10043882Bwtq13_mbody weight QTL 13 (mouse)Not determined33375204567752228Mouse
15039332Nmrs6_mNAFLD-associated magnetic resonance shift 6 (mouse)33417074168170741Mouse
15039336Nmrs2_mNAFLD-associated magnetic resonance shift 2 (mouse)33457610368576103Mouse
18337272Bmd46_mbone mineral density 46, males (mouse)33540742169407421Mouse
14746977Manh53_mmandible shape 53 (mouse)33592528069925280Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
1300587Aod2_mautoimmune ovarian dysgenesis 2 (mouse)Not determined33717974268716946Mouse
11041901Lmr11b_mleishmaniasis resistance 11b (mouse)33970410273704231Mouse
11039513Ltpr3a_mLeishmania tropica response 3a (mouse)33970410273704231Mouse
1301585Cd4ts1_mCD4 T cell subset 1 (mouse)Not determined33970410273704231Mouse
10755516Amzn1_manatomical modifier of Zfp423 1 (mouse)33970410273704231Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4935758183357581Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34949500583495118Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34949500583495118Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35262550986625745Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35262550986625745Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35262550986625745Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35292318386923183Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse

Markers in Region
AI607804  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38366,220,507 - 66,220,587UniSTSGRCm38
MGSCv37366,024,429 - 66,024,509UniSTSGRCm37
Celera366,364,540 - 66,364,620UniSTS
Cytogenetic Map3E1UniSTS
cM Map333.8UniSTS
Whitehead/MRC_RH3590.17UniSTS
U33842  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38366,220,565 - 66,220,705UniSTSGRCm38
MGSCv37366,024,487 - 66,024,627UniSTSGRCm37
Celera366,364,598 - 66,364,738UniSTS
Cytogenetic Map3E1UniSTS
cM Map333.8UniSTS
Whitehead/MRC_RH3594.06UniSTS
X83601  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3E1UniSTS
cM Map333.8UniSTS
Whitehead_YAC3 UniSTS
PMC304098P4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38366,224,868 - 66,224,975UniSTSGRCm38
MGSCv37366,028,790 - 66,028,897UniSTSGRCm37
Celera366,368,901 - 66,369,008UniSTS
Cytogenetic Map3E1UniSTS
cM Map333.8UniSTS
Ptx3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38366,225,209 - 66,225,733UniSTSGRCm38
MGSCv37366,029,131 - 66,029,655UniSTSGRCm37
Celera366,369,242 - 66,369,766UniSTS
Cytogenetic Map3E1UniSTS
cM Map333.8UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000029421   ⟹   ENSMUSP00000029421
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl366,127,331 - 66,133,226 (+)Ensembl
GRCm38.p6 Ensembl366,219,910 - 66,225,805 (+)Ensembl
RefSeq Acc Id: ENSMUST00000182521
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl366,127,666 - 66,128,851 (+)Ensembl
GRCm38.p6 Ensembl366,220,245 - 66,221,430 (+)Ensembl
RefSeq Acc Id: NM_008987   ⟹   NP_033013
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39366,127,308 - 66,133,227 (+)NCBI
GRCm38366,219,887 - 66,225,806 (+)ENTREZGENE
MGSCv37366,023,809 - 66,029,728 (+)RGD
Celera366,363,920 - 66,369,839 (+)RGD
cM Map3 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_033013 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52273 (Get FASTA)   NCBI Sequence Viewer  
  AAH22176 (Get FASTA)   NCBI Sequence Viewer  
  CAA58580 (Get FASTA)   NCBI Sequence Viewer  
  CBH19820 (Get FASTA)   NCBI Sequence Viewer  
  EDL15532 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000029421
  ENSMUSP00000029421.5
GenBank Protein P48759 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_033013   ⟸   NM_008987
- Peptide Label: precursor
- UniProtKB: Q8VDF1 (UniProtKB/Swiss-Prot),   P48759 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000029421   ⟸   ENSMUST00000029421
Protein Domains
Pentraxin (PTX)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P48759-F1-model_v2 AlphaFold P48759 1-381 view protein structure

Promoters
RGD ID:6834331
Promoter ID:MM_KWN:34526
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   MEF_B4,   MEF_B6
Transcripts:NM_008987
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36366,023,721 - 66,024,221 (+)MPROMDB
RGD ID:6880820
Promoter ID:EPDNEW_M3861
Type:multiple initiation site
Name:Ptx3_1
Description:Mus musculus pentraxin related gene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38366,219,979 - 66,220,039EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104641 AgrOrtholog
Ensembl Genes ENSMUSG00000027832 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000029421 ENTREZGENE
  ENSMUST00000029421.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot
  Pentaxin_CS UniProtKB/Swiss-Prot
  Pentraxin-related UniProtKB/Swiss-Prot
  PTX3 UniProtKB/Swiss-Prot
KEGG Report mmu:19288 UniProtKB/Swiss-Prot
MGD MGI:104641 ENTREZGENE
NCBI Gene 19288 ENTREZGENE
PANTHER PENTRAXIN-RELATED PROTEIN PTX3 UniProtKB/Swiss-Prot
  PTHR46943 UniProtKB/Swiss-Prot
Pfam Pentaxin UniProtKB/Swiss-Prot
PhenoGen Ptx3 PhenoGen
PRINTS PENTAXIN UniProtKB/Swiss-Prot
PROSITE PTX_1 UniProtKB/Swiss-Prot
  PTX_2 UniProtKB/Swiss-Prot
SMART PTX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt P48759 ENTREZGENE, UniProtKB/Swiss-Prot
  Q8VDF1 ENTREZGENE
UniProt Secondary Q8VDF1 UniProtKB/Swiss-Prot