Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fundc2 | Mouse | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of FUNDC2 mRNA | CTD | PMID:36331819 | Fundc2 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of FUNDC2 mRNA] | CTD | PMID:22206623 | Fundc2 | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of FUNDC2 mRNA | CTD | PMID:22206623 | Fundc2 | Mouse | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FUNDC2 mRNA | CTD | PMID:17942748 | Fundc2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FUNDC2 mRNA | CTD | PMID:17942748 | Fundc2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FUNDC2 mRNA | CTD | PMID:21570461 | Fundc2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FUNDC2 mRNA | CTD | PMID:21215274 | Fundc2 | Mouse | 4,4'-diaminodiphenylmethane | affects expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of FUNDC2 mRNA | CTD | PMID:18648102 | Fundc2 | Mouse | 4,4'-sulfonyldiphenol | increases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of FUNDC2 protein | CTD | PMID:34186270 | Fundc2 | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of FUNDC2 mRNA | CTD | PMID:22504374 | Fundc2 | Mouse | aconitine | decreases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Aconitine results in decreased expression of FUNDC2 protein | CTD | PMID:33236894 | Fundc2 | Mouse | acrylamide | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of FUNDC2 mRNA | CTD | PMID:28959563 | Fundc2 | Mouse | aflatoxin B1 | decreases methylation | ISO | FUNDC2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FUNDC2 gene | CTD | PMID:27153756 | Fundc2 | Mouse | amiodarone | increases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of FUNDC2 mRNA | CTD | PMID:19774075 | Fundc2 | Mouse | atrazine | increases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | Atrazine results in increased expression of FUNDC2 mRNA | CTD | PMID:22378314 | Fundc2 | Mouse | benzo[a]pyrene | affects methylation | ISO | FUNDC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FUNDC2 promoter | CTD | PMID:27901495 | Fundc2 | Mouse | benzo[a]pyrene | increases methylation | ISO | FUNDC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FUNDC2 5' UTR | CTD | PMID:27901495 | Fundc2 | Mouse | bisphenol A | affects expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of FUNDC2 mRNA | CTD | PMID:25181051 | Fundc2 | Mouse | bisphenol A | increases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of FUNDC2 protein | CTD | PMID:34186270 | Fundc2 | Mouse | bisphenol A | decreases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of FUNDC2 mRNA | CTD | PMID:30816183 and PMID:32528016 | Fundc2 | Mouse | bisphenol F | increases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of FUNDC2 protein | CTD | PMID:34186270 | Fundc2 | Mouse | CGP 52608 | multiple interactions | ISO | FUNDC2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to FUNDC2 gene] | CTD | PMID:28238834 | Fundc2 | Mouse | copper(II) sulfate | decreases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of FUNDC2 mRNA | CTD | PMID:19549813 | Fundc2 | Mouse | corosolic acid | increases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | corosolic acid results in increased expression of FUNDC2 mRNA | CTD | PMID:37939859 | Fundc2 | Mouse | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of FUNDC2 mRNA | CTD | PMID:29279043 | Fundc2 | Mouse | doxorubicin | decreases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of FUNDC2 mRNA | CTD | PMID:29803840 | Fundc2 | Mouse | endosulfan | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of FUNDC2 mRNA | CTD | PMID:29391264 | Fundc2 | Mouse | flutamide | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of FUNDC2 mRNA | CTD | PMID:24136188 | Fundc2 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of FUNDC2 mRNA] | CTD | PMID:22206623 | Fundc2 | Mouse | FR900359 | decreases phosphorylation | ISO | FUNDC2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of FUNDC2 protein | CTD | PMID:37730182 | Fundc2 | Mouse | furan | increases methylation | ISO | Fundc2 (Rattus norvegicus) | 6480464 | furan results in increased methylation of FUNDC2 gene | CTD | PMID:22079235 | Fundc2 | Mouse | gentamycin | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of FUNDC2 mRNA | CTD | PMID:33387578 | Fundc2 | Mouse | glafenine | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of FUNDC2 mRNA | CTD | PMID:24136188 | Fundc2 | Mouse | methapyrilene | decreases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of FUNDC2 mRNA | CTD | PMID:30467583 | Fundc2 | Mouse | methimazole | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of FUNDC2 mRNA | CTD | PMID:22504374 | Fundc2 | Mouse | nickel sulfate | decreases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of FUNDC2 mRNA | CTD | PMID:22714537 | Fundc2 | Mouse | paracetamol | affects expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | Acetaminophen affects the expression of FUNDC2 mRNA | CTD | PMID:25704631 | Fundc2 | Mouse | paracetamol | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of FUNDC2 mRNA | CTD | PMID:33387578 | Fundc2 | Mouse | perfluorohexanesulfonic acid | increases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in increased expression of FUNDC2 mRNA | CTD | PMID:37995155 | Fundc2 | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of FUNDC2 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of FUNDC2 mRNA | CTD | PMID:36331819 | Fundc2 | Mouse | permethrin | decreases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | Permethrin results in decreased expression of FUNDC2 mRNA | CTD | PMID:37047231 | Fundc2 | Mouse | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of FUNDC2 mRNA | CTD | PMID:18301758 | Fundc2 | Mouse | potassium chromate | decreases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of FUNDC2 mRNA | CTD | PMID:22714537 | Fundc2 | Mouse | Soman | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Soman results in increased expression of FUNDC2 mRNA | CTD | PMID:19281266 | Fundc2 | Mouse | thapsigargin | decreases expression | EXP | | 6480464 | Thapsigargin results in decreased expression of FUNDC2 protein | CTD | PMID:24648495 | Fundc2 | Mouse | trichloroethene | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of FUNDC2 mRNA | CTD | PMID:33387578 | Fundc2 | Mouse | triphenyl phosphate | increases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of FUNDC2 mRNA | CTD | PMID:30589522 | Fundc2 | Mouse | Triptolide | decreases expression | ISO | Fundc2 (Rattus norvegicus) | 6480464 | triptolide results in decreased expression of FUNDC2 protein | CTD | PMID:32519852 | Fundc2 | Mouse | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of FUNDC2 mRNA | CTD | PMID:28973697 | Fundc2 | Mouse | tungsten | increases expression | EXP | | 6480464 | Tungsten results in increased expression of FUNDC2 mRNA | CTD | PMID:30912803 | Fundc2 | Mouse | valproic acid | decreases expression | ISO | FUNDC2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FUNDC2 mRNA | CTD | PMID:23179753 | |