Myl1 (myosin, light polypeptide 1) - Rat Genome Database

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Gene: Myl1 (myosin, light polypeptide 1) Mus musculus
Analyze
Symbol: Myl1
Name: myosin, light polypeptide 1
RGD ID: 1557603
MGI Page MGI
Description: Predicted to be a structural constituent of muscle. Predicted to be involved in cardiac muscle contraction. Predicted to be located in myofibril. Predicted to be part of myosin II complex. Predicted to be active in contractile muscle fiber. Is expressed in several structures, including diaphragm; embryo mesenchyme; eye; heart; and skeletal musculature. Human ortholog(s) of this gene implicated in congenital myopathy 14. Orthologous to human MYL1 (myosin light chain 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A1 catalytic; A2 catalytic; AI325107; atrial, embryonic; D12Mgi4; MLC1; MLC1/MLC3; MLC1f; MLC1F/MLC3F; MLC3; MLC3f; Myl; Mylf; myosin light chain 1/3, skeletal muscle isoform; myosin light chain A1/A2; myosin light chain alkali 1/2; myosin light chain, alkali, fast skeletal muscle; myosin, light polypeptide 1, alkali; myosin, light polypeptide 1, alkali, atrial, embryonic; myosin, light polypeptide 4, alkali; myosin, light polypeptide 4, alkali, atrial, embryonic
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Mylf-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39166,963,454 - 66,987,091 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl166,963,454 - 66,984,563 (-)EnsemblGRCm39 Ensembl
GRCm38166,924,295 - 66,947,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl166,924,295 - 66,945,404 (-)EnsemblGRCm38mm10GRCm38
MGSCv37166,970,869 - 66,991,630 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36166,857,506 - 66,878,240 (-)NCBIMGSCv36mm8
Celera167,442,110 - 67,462,688 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-noradrenaline  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
capsaicin  (ISO)
carbofuran  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chelerythrine  (ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (EXP)
clozapine  (ISO)
deguelin  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diuron  (ISO)
doxorubicin  (ISO)
fasudil  (ISO)
fenthion  (EXP)
folic acid  (EXP)
graphite  (EXP)
Indeno[1,2,3-cd]pyrene  (EXP)
isoprenaline  (ISO)
ivermectin  (ISO)
methanol  (ISO)
methotrexate  (EXP)
methylmercury chloride  (ISO)
milrinone  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nickel subsulfide  (ISO)
nickel sulfate  (EXP)
ozone  (EXP)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (EXP)
phenylephrine  (ISO)
pioglitazone  (EXP)
progesterone  (ISO)
razoxane  (ISO)
resveratrol  (ISO)
scoparone  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
spermine  (EXP)
tamoxifen  (EXP)
Tanshinone I  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
triclosan  (ISO)
triticonazole  (ISO)
valproic acid  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cellular respiration  (IAGP)
abnormal cholesterol homeostasis  (IAGP)
abnormal extraembryonic endoderm formation  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal locomotor coordination  (IAGP)
abnormal mitochondrial crista morphology  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal muscle fiber mitochondrial morphology  (IAGP)
abnormal muscle fiber morphology  (IAGP)
abnormal muscle physiology  (IAGP)
abnormal muscle spindle morphology  (IAGP)
abnormal oxidative phosphorylation  (IAGP)
abnormal respiratory electron transport chain  (IAGP)
abnormal response to exercise  (IAGP)
abnormal skeletal muscle morphology  (IAGP)
abnormal visceral yolk sac cavity morphology  (IAGP)
absent mesoderm  (IAGP)
ataxia  (IAGP)
bradykinesia  (IAGP)
cachexia  (IAGP)
decreased aerobic running capacity  (IAGP)
decreased body size  (IAGP)
decreased circulating insulin level  (IAGP)
decreased embryo size  (IAGP)
decreased grip strength  (IAGP)
decreased liver glycogen level  (IAGP)
decreased locomotor activity  (IAGP)
decreased mitochondrial size  (IAGP)
decreased muscle spindle number  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased skeletal muscle fiber mitochondrial DNA content  (IAGP)
decreased skeletal muscle glycogen level  (IAGP)
decreased skeletal muscle mass  (IAGP)
decreased skeletal muscle weight  (IAGP)
decreased survivor rate  (IAGP)
disorganized mitochondrial cristae  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality between somite formation and embryo turning, incomplete penetrance  (IAGP)
failure of primitive streak formation  (IAGP)
hypoglycemia  (IAGP)
impaired autophagy  (IAGP)
impaired exercise endurance  (IAGP)
impaired glucose tolerance  (IAGP)
impaired limb coordination  (IAGP)
impaired skeletal muscle contractility  (IAGP)
improved glucose tolerance  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating free fatty acids level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased lean body mass  (IAGP)
increased muscle cell glucose uptake  (IAGP)
increased muscle fatigability  (IAGP)
increased skeletal muscle fiber diameter  (IAGP)
increased skeletal muscle fiber size  (IAGP)
increased skeletal muscle glycogen level  (IAGP)
increased skeletal muscle weight  (IAGP)
increased variability of skeletal muscle fiber size  (IAGP)
insulin resistance  (IAGP)
kyphosis  (IAGP)
myopathy  (IAGP)
no abnormal phenotype detected  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
skeletal muscle fiber atrophy  (IAGP)
skeletal muscle fiber degeneration  (IAGP)
skeletal muscle hypertrophy  (IAGP)
weakness  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1581633   PMID:1685142   PMID:1685480   PMID:1901785   PMID:1962752   PMID:1970800   PMID:2025291   PMID:2201580   PMID:2211821   PMID:2534378   PMID:2696048   PMID:2892781  
PMID:2983233   PMID:3022377   PMID:3194193   PMID:3242494   PMID:3865381   PMID:4942892   PMID:6091905   PMID:6283523   PMID:7588068   PMID:7720708   PMID:7721942   PMID:7787235  
PMID:7828830   PMID:8136524   PMID:8207020   PMID:8288247   PMID:8404542   PMID:8587605   PMID:8668209   PMID:8751373   PMID:8754853   PMID:8950513   PMID:9242416   PMID:9489771  
PMID:9689582   PMID:10349636   PMID:10686620   PMID:11042159   PMID:11076861   PMID:11090542   PMID:11884037   PMID:12417746   PMID:12466851   PMID:12477932   PMID:12819125   PMID:15082723  
PMID:15499557   PMID:16103131   PMID:16141072   PMID:16141073   PMID:16494860   PMID:16996481   PMID:17289669   PMID:17380205   PMID:17626887   PMID:18054315   PMID:18062958   PMID:18554416  
PMID:18694957   PMID:18753145   PMID:18945718   PMID:18957633   PMID:18973680   PMID:19506036   PMID:19661286   PMID:19945408   PMID:19962975   PMID:20065166   PMID:20403324   PMID:20625437  
PMID:20814569   PMID:20861693   PMID:21037586   PMID:21109195   PMID:21253590   PMID:21267068   PMID:21873635   PMID:21946846   PMID:22190261   PMID:22267199   PMID:22522309   PMID:22673621  
PMID:23202295   PMID:23369715   PMID:23504871   PMID:23516375   PMID:23630012   PMID:23734214   PMID:23892084   PMID:24076600   PMID:24145720   PMID:24154528   PMID:24227653   PMID:24487027  
PMID:24567902   PMID:24632224   PMID:24662047   PMID:24713655   PMID:24844572   PMID:24876160   PMID:24938781   PMID:25172430   PMID:25176656   PMID:25380823   PMID:25496993   PMID:25794679  
PMID:25858807   PMID:25982555   PMID:26011449   PMID:26056297   PMID:26214036   PMID:26306597   PMID:26331883   PMID:26374844   PMID:26411342   PMID:26446156   PMID:26603188   PMID:26629406  
PMID:26732653   PMID:27302464   PMID:27334614   PMID:27508874   PMID:27541056   PMID:27566547   PMID:27600775   PMID:27644105   PMID:27825107   PMID:27986797   PMID:27991918   PMID:28011087  
PMID:28122718   PMID:28319140   PMID:28378742   PMID:28475869   PMID:28642969   PMID:28683291   PMID:28943449   PMID:29069356   PMID:29240830   PMID:29253568   PMID:29255421   PMID:29459677  
PMID:29641213   PMID:29657030   PMID:29898916   PMID:30096135   PMID:30232375   PMID:30554447   PMID:30654731   PMID:30830866   PMID:30865515   PMID:30870781   PMID:30895728   PMID:30902524  
PMID:30913396   PMID:30918582   PMID:30964448   PMID:30989113   PMID:31129047   PMID:31189900   PMID:31208084   PMID:31241461   PMID:31356902   PMID:31530015   PMID:31577158   PMID:31916679  
PMID:31923383   PMID:32212902   PMID:32327658   PMID:32691494   PMID:32930093   PMID:33042761   PMID:33057669   PMID:33137160   PMID:33315859   PMID:33568757   PMID:33798773   PMID:33857757  
PMID:34006859   PMID:34204316   PMID:34212132   PMID:34378772   PMID:34550736   PMID:35228746   PMID:35254259   PMID:35290243   PMID:35306755   PMID:35379817   PMID:35464088   PMID:35593053  
PMID:35765148   PMID:36198696   PMID:36237181   PMID:36479146   PMID:36598990   PMID:36669097   PMID:36864049   PMID:37097817   PMID:37172728   PMID:37222423   PMID:37284884   PMID:37334900  
PMID:37524711   PMID:37624892   PMID:37734370   PMID:38226173   PMID:38678560  


Genomics

Comparative Map Data
Myl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39166,963,454 - 66,987,091 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl166,963,454 - 66,984,563 (-)EnsemblGRCm39 Ensembl
GRCm38166,924,295 - 66,947,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl166,924,295 - 66,945,404 (-)EnsemblGRCm38mm10GRCm38
MGSCv37166,970,869 - 66,991,630 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36166,857,506 - 66,878,240 (-)NCBIMGSCv36mm8
Celera167,442,110 - 67,462,688 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.71NCBI
MYL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382210,290,150 - 210,315,174 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2210,290,150 - 210,315,174 (-)EnsemblGRCh38hg38GRCh38
GRCh372211,154,874 - 211,179,898 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362210,863,113 - 210,888,140 (-)NCBINCBI36Build 36hg18NCBI36
Build 342210,980,382 - 210,993,845NCBI
Celera2204,922,877 - 204,947,923 (-)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2203,000,114 - 203,025,138 (-)NCBIHuRef
CHM1_12211,160,958 - 211,186,022 (-)NCBICHM1_1
T2T-CHM13v2.02210,770,853 - 210,795,901 (-)NCBIT2T-CHM13v2.0
Myl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2968,437,514 - 68,458,256 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl968,437,517 - 68,458,261 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx976,926,694 - 76,947,188 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0982,055,627 - 82,076,116 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0980,461,970 - 80,482,459 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0973,937,820 - 73,958,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl973,937,823 - 73,958,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0973,349,226 - 73,369,886 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4965,717,097 - 65,737,576 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera965,916,653 - 65,937,125 (-)NCBICelera
Cytogenetic Map9q32NCBI
Myl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554575,146,633 - 5,168,356 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554575,147,443 - 5,167,587 (+)NCBIChiLan1.0ChiLan1.0
MYL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213112,913,613 - 112,938,932 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B112,928,593 - 112,953,912 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B97,548,013 - 97,573,336 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B215,940,808 - 215,974,852 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B215,950,087 - 215,974,852 (-)Ensemblpanpan1.1panPan2
MYL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13718,143,644 - 18,168,208 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3718,143,673 - 18,168,187 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3719,024,436 - 19,048,975 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03718,081,858 - 18,106,400 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3718,050,944 - 18,106,386 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13718,034,367 - 18,058,915 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03717,996,703 - 18,021,269 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03718,011,588 - 18,036,161 (-)NCBIUU_Cfam_GSD_1.0
Myl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303166,612,434 - 166,632,566 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365865,993,098 - 6,013,994 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365865,993,177 - 6,013,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15113,036,228 - 113,063,321 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115113,038,083 - 113,051,315 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215124,861,888 - 124,875,123 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap15q23-q26NCBI
MYL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11096,015,186 - 96,041,862 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1096,015,034 - 96,029,160 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040103,314,602 - 103,340,346 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247655,883,524 - 5,904,179 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247655,883,908 - 5,903,759 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myl1
159 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:565
Count of miRNA genes:391
Interacting mature miRNAs:449
Transcripts:ENSMUST00000027151, ENSMUST00000119429, ENSMUST00000120415, ENSMUST00000150542, ENSMUST00000151328, ENSMUST00000160100
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
4142015Idd5.3_minsulin dependent diabetes susceptibility 5.3 (mouse)Not determined6652316270077076Mouse
12910788Pwgrq9_mpost-weaning growth rate QTL 9 (mouse)14086800867270256Mouse
18182931Metl1_mmetabolite locus 1, pyridoxate (mouse)14127539975275399Mouse
12910786Pwgrq10_mpost-weaning growth rate QTL 10 (mouse)14086800867270256Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1357824Estoq4_membryo survival total QTL 4 (mouse)Not determined13476013873976915Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15794135191941351Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15799197791992080Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
10043965Obq24_mobesity QTL 24 (mouse)Not determined15089021684890216Mouse
1301430Cdcs2_mcytokine deficiency colitis susceptibility 2 (mouse)Not determined14889234582892485Mouse
1558717Ses1a_msalmonella enteritidis susceptibility 1a (mouse)Not determined15672692290727077Mouse
1357759W3q12_mweight 3 weeks QTL 12 (mouse)Not determined13476013873976915Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15854919192549443Mouse
1558822Vas1_mautoimmune vasitis resistance 1 (mouse)Not determined14888900682889210Mouse
1301670Ssta1_msusceptibility to Salmonella typhimurium antigens 1 (mouse)Not determined14594675579946882Mouse
1357475w3q13_mweight 3 weeks QTL 13 (mouse)Not determined12310959173976915Mouse
1357741Nidd5k_mNidd5 on KK-A<y> (mouse)Not determined15597494889975057Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15799197791992080Mouse
4142467Wbcq1_mwhite blood cell quantitative locus 1 (mouse)Not determined15626621490266360Mouse
1301166Thypr2_mthymocyte proliferative response 2 (mouse)Not determined14127312475273271Mouse
1301933Insq6_minsulin QTL 6 (mouse)Not determined15672692290727077Mouse
1357524W6q14_mweight 6 weeks QTL 14 (mouse)Not determined13476013873976915Mouse
1301714Vertcling_mvertical clinging (mouse)Not determined14293803176938167Mouse
4141305Tgq9_mtriglyceride QTL 9 (mouse)Not determined5142160585421605Mouse
1357651Lgq5_mlate growth QTL 5 (mouse)Not determined13476013873976915Mouse
1301211Bbaa11_mB.burgdorferi-associated arthritis 11 (mouse)Not determined14888900682889210Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
1558855Eae30_mexperimental allergic encephalomyelitis susceptibility 30 (mouse)Not determined14541777372975057Mouse
1301954Lrnx11_mlearning-contextual 11 (mouse)Not determined13913280874516365Mouse
1357505Vtbt1_mvertebral trabecular bone trait 1 (mouse)Not determined15626621490266360Mouse
1357506W10q6_mweight 10 weeks QTL 6 (mouse)Not determined13476013873976915Mouse
4141032Wbcc1_mwhite blood cell count 1 (mouse)Not determined4225966776259667Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15854919192549443Mouse
39128207Lwq16_mliver weight QTL 16 (mouse)13476013873976915Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
4142307Shali1_msurvival time to hyperoxic acute lung injury 1 (mouse)Not determined5196402570406589Mouse
14747009Manh49_mmandible shape 49 (mouse)15794135191941351Mouse
1301616Yaa2_mY-linked autoimmune acceleration 2 (mouse)Not determined14685469080854839Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1558905Gct7_mgranulosa cell tumorigenesis 7 (mouse)Not determined14734989481350013Mouse
1302119Cia15_mcollagen induced arthritis 15 (mouse)Not determined16588900688496101Mouse
12910780Pwgrq11_mpost-weaning growth rate QTL 11 (mouse)14086800867270256Mouse
1301225Sle7_msystematic lupus erythematosus susceptibility 7 (mouse)Not determined14685469080854839Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15799197791992080Mouse

Markers in Region
RH129698  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38166,924,344 - 66,924,533UniSTSGRCm38
MGSCv37166,970,918 - 66,971,107UniSTSGRCm37
Cytogenetic Map1C3UniSTS
cM Map134.1UniSTS
AI325107  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812101,221,907 - 101,221,987UniSTSGRCm38
MGSCv3712102,460,117 - 102,460,197UniSTSGRCm37
Celera12102,450,500 - 102,450,580UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map1C3UniSTS
cM Map134.1UniSTS
Whitehead/MRC_RH12934.83UniSTS
D1Mit21.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38166,946,344 - 66,946,456UniSTSGRCm38
MGSCv37166,992,918 - 66,993,030UniSTSGRCm37
Celera167,463,982 - 67,464,094UniSTS
Cytogenetic Map1C3UniSTS
cM Map132.8UniSTS
cM Map1 UniSTS
Whitehead Genetic134.2306UniSTS
Whitehead_YAC1 UniSTS
Mylf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1C3UniSTS
cM Map134.1UniSTS
D1Mit21  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38166,946,183 - 66,946,425UniSTSGRCm38
MGSCv37166,992,757 - 66,992,999UniSTSGRCm37
Celera167,463,815 - 67,464,063UniSTS
Cytogenetic Map1C3UniSTS
cM Map132.8UniSTS
Whitehead Genetic132.8UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001113387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011238451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC133187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY785713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU407305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  K02242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W48198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W87050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X12973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000027151   ⟹   ENSMUSP00000027151
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,963,454 - 66,984,302 (-)Ensembl
GRCm38.p6 Ensembl166,924,295 - 66,945,143 (-)Ensembl
Ensembl Acc Id: ENSMUST00000119429   ⟹   ENSMUSP00000112861
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,963,457 - 66,974,513 (-)Ensembl
GRCm38.p6 Ensembl166,924,298 - 66,935,354 (-)Ensembl
Ensembl Acc Id: ENSMUST00000120415   ⟹   ENSMUSP00000112880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,965,225 - 66,974,492 (-)Ensembl
GRCm38.p6 Ensembl166,926,066 - 66,935,333 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150542
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,964,182 - 66,974,509 (-)Ensembl
GRCm38.p6 Ensembl166,925,023 - 66,935,350 (-)Ensembl
Ensembl Acc Id: ENSMUST00000151328
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,983,622 - 66,984,563 (-)Ensembl
GRCm38.p6 Ensembl166,944,463 - 66,945,404 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160100   ⟹   ENSMUSP00000125748
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,965,781 - 66,984,543 (-)Ensembl
GRCm38.p6 Ensembl166,926,622 - 66,945,384 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186202   ⟹   ENSMUSP00000140834
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,963,454 - 66,974,796 (-)Ensembl
GRCm38.p6 Ensembl166,924,295 - 66,935,637 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186346
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,969,351 - 66,973,857 (-)Ensembl
GRCm38.p6 Ensembl166,930,192 - 66,934,698 (-)Ensembl
RefSeq Acc Id: NM_001113387   ⟹   NP_001106858
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,974,507 (-)NCBI
GRCm38166,924,295 - 66,935,366 (-)NCBI
MGSCv37166,970,869 - 66,991,630 (-)RGD
Celera167,442,110 - 67,462,688 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001420333   ⟹   NP_001407262
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,984,637 (-)NCBI
RefSeq Acc Id: NM_001420334   ⟹   NP_001407263
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,974,507 (-)NCBI
RefSeq Acc Id: NM_021285   ⟹   NP_067260
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,984,189 (-)NCBI
GRCm38166,924,295 - 66,945,056 (-)NCBI
MGSCv37166,970,869 - 66,991,630 (-)RGD
Celera167,442,110 - 67,462,688 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011238451   ⟹   XP_011236753
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,965,225 - 66,974,541 (-)NCBI
GRCm38166,926,066 - 66,935,407 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162616   ⟹   XP_036018509
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,987,091 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162618   ⟹   XP_036018511
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,987,091 (-)NCBI
Sequence:
RefSeq Acc Id: NP_067260   ⟸   NM_021285
- Peptide Label: isoform 1f
- UniProtKB: P05978 (UniProtKB/Swiss-Prot),   P05977 (UniProtKB/Swiss-Prot),   Q545T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106858   ⟸   NM_001113387
- Peptide Label: isoform 3f
- UniProtKB: Q545G5 (UniProtKB/TrEMBL),   Q6PCW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011236753   ⟸   XM_011238451
- Peptide Label: isoform X2
- UniProtKB: E9PWG4 (UniProtKB/TrEMBL),   Q6PCW9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000027151   ⟸   ENSMUST00000027151
Ensembl Acc Id: ENSMUSP00000112861   ⟸   ENSMUST00000119429
Ensembl Acc Id: ENSMUSP00000140834   ⟸   ENSMUST00000186202
Ensembl Acc Id: ENSMUSP00000125748   ⟸   ENSMUST00000160100
Ensembl Acc Id: ENSMUSP00000112880   ⟸   ENSMUST00000120415
RefSeq Acc Id: XP_036018509   ⟸   XM_036162616
- Peptide Label: isoform X1
- UniProtKB: P05977 (UniProtKB/Swiss-Prot),   P05978 (UniProtKB/Swiss-Prot),   Q545T7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036018511   ⟸   XM_036162618
- Peptide Label: isoform X1
- UniProtKB: P05977 (UniProtKB/Swiss-Prot),   P05978 (UniProtKB/Swiss-Prot),   Q545T7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001407262   ⟸   NM_001420333
- Peptide Label: isoform 1f
- UniProtKB: P05978 (UniProtKB/Swiss-Prot),   P05977 (UniProtKB/Swiss-Prot),   Q545T7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001407263   ⟸   NM_001420334
- Peptide Label: isoform 3f
- UniProtKB: Q545G5 (UniProtKB/TrEMBL),   Q6PCW9 (UniProtKB/TrEMBL)
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05977-F1-model_v2 AlphaFold P05977 1-188 view protein structure

Promoters
RGD ID:6873982
Promoter ID:EPDNEW_M442
Type:multiple initiation site
Name:Myl1_1
Description:Mus musculus myosin, light polypeptide 1 , transcript variant3f, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M443  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38166,935,348 - 66,935,408EPDNEW
RGD ID:6873984
Promoter ID:EPDNEW_M443
Type:initiation region
Name:Myl1_2
Description:Mus musculus myosin, light polypeptide 1 , transcript variant3f, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M442  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38166,945,030 - 66,945,090EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97269 AgrOrtholog
Ensembl Genes ENSMUSG00000061816 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000027151 ENTREZGENE
  ENSMUST00000027151.12 UniProtKB/Swiss-Prot
  ENSMUST00000119429 ENTREZGENE
  ENSMUST00000119429.8 UniProtKB/Swiss-Prot
  ENSMUST00000120415 ENTREZGENE
  ENSMUST00000120415.8 UniProtKB/TrEMBL
  ENSMUST00000160100.2 UniProtKB/TrEMBL
  ENSMUST00000186202.7 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ca-Reg_Muscle_Contr_Cell_Proc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17901 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97269 ENTREZGENE
NCBI Gene 17901 ENTREZGENE
PANTHER MYOSIN LIGHT CHAIN 1, 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYOSIN LIGHT CHAIN 1/3, SKELETAL MUSCLE ISOFORM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myl1 PhenoGen
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WRZ7_MOUSE UniProtKB/TrEMBL
  E0CZ30_MOUSE UniProtKB/TrEMBL
  E9PWG4 ENTREZGENE, UniProtKB/TrEMBL
  MYL1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  P05978 ENTREZGENE
  Q545G5 ENTREZGENE, UniProtKB/TrEMBL
  Q545T7 ENTREZGENE, UniProtKB/TrEMBL
  Q6PCW9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P05978 UniProtKB/Swiss-Prot