Tbx3 (T-box 3) - Rat Genome Database

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Gene: Tbx3 (T-box 3) Mus musculus
Analyze
Symbol: Tbx3
Name: T-box 3
RGD ID: 1557562
MGI Page MGI
Description: Enables DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including atrioventricular canal morphogenesis; embryonic morphogenesis; and regulation of protein complex stability. Acts upstream of or within several processes, including circulatory system development; mammary gland morphogenesis; and regulation of DNA-templated transcription. Located in nucleus. Part of transcription regulator complex. Is active in cilium. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study ulnar-mammary syndrome. Human ortholog(s) of this gene implicated in ulnar-mammary syndrome. Orthologous to human TBX3 (T-box transcription factor 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D5Ertd189; D5Ertd189e; T-box protein 3; T-box transcription factor TBX3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395119,808,600 - 119,822,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5119,808,734 - 119,822,789 (+)EnsemblGRCm39 Ensembl
GRCm385119,670,534 - 119,684,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5119,670,669 - 119,684,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv375120,120,678 - 120,134,610 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365119,931,286 - 119,945,218 (+)NCBIMGSCv36mm8
Celera5116,764,719 - 116,778,686 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map560.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,8-cineole  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (ISO)
amiodarone  (ISO)
amitrole  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (ISO)
bisphenol F  (EXP)
bromobenzene  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
carnosic acid  (EXP)
cefaloridine  (ISO)
chlordecone  (EXP)
ciguatoxin CTX1B  (EXP)
clofibrate  (EXP)
cobalt atom  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cycloheximide  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (EXP)
dexamethasone  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
dimethoate  (ISO)
disodium selenite  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
enzacamene  (ISO)
epoxiconazole  (EXP)
fenvalerate  (ISO)
folic acid  (EXP)
fonofos  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (ISO)
GW 4064  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
Iopanoic acid  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
metformin  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (EXP)
Muraglitazar  (ISO)
N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide  (EXP)
nickel atom  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
parathion  (ISO)
PD 0325901  (ISO)
PD173074  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
PF-3758309  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
propiconazole  (EXP)
Ptaquiloside  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
ritodrine  (EXP)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
sorafenib  (ISO)
sulfadimethoxine  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
taiwanin C  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
troglitazone  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (ISO)
anterior/posterior axis specification, embryo  (ISO,ISS)
atrioventricular bundle cell differentiation  (IMP)
atrioventricular canal development  (IGI)
atrioventricular canal morphogenesis  (IGI)
blood vessel development  (IMP)
branching involved in mammary gland duct morphogenesis  (IMP)
cardiac epithelial to mesenchymal transition  (IEA,ISO)
cardiac jelly development  (IEA,ISO)
cardiac muscle cell differentiation  (IMP)
cardiac muscle cell fate commitment  (IMP)
cell fate specification  (IBA)
cellular senescence  (IDA,ISO,ISS)
DNA-templated transcription  (IMP)
embryonic digit morphogenesis  (IMP,ISO,ISS)
embryonic forelimb morphogenesis  (ISO,ISS)
embryonic heart tube development  (IMP)
embryonic hindlimb morphogenesis  (IMP)
endocardial cushion formation  (IEA,ISO)
female genitalia development  (ISO,ISS)
follicle-stimulating hormone secretion  (ISO,ISS)
forelimb morphogenesis  (ISO)
heart looping  (IMP)
heart morphogenesis  (IMP)
hepatoblast differentiation  (IMP)
in utero embryonic development  (IMP)
inner ear morphogenesis  (IGI)
limb morphogenesis  (IMP)
limbic system development  (IMP)
luteinizing hormone secretion  (ISO,ISS)
male genitalia development  (ISO,ISS)
mammary gland development  (IMP,ISO)
mammary placode formation  (IDA,IGI)
mesoderm morphogenesis  (ISO,ISS)
negative regulation of apoptotic process  (ISO,ISS)
negative regulation of cell proliferation involved in heart morphogenesis  (IEA,ISO)
negative regulation of DNA-templated transcription  (IDA,IMP,ISO,ISS)
negative regulation of epithelial cell differentiation  (IMP)
negative regulation of myoblast differentiation  (ISO,ISS)
negative regulation of stem cell differentiation  (IMP)
negative regulation of transcription by RNA polymerase II  (IMP,ISO)
outflow tract morphogenesis  (IMP)
positive regulation of cell cycle  (ISO,ISS)
positive regulation of cell population proliferation  (ISO)
positive regulation of DNA-templated transcription  (IMP)
positive regulation of stem cell proliferation  (IMP)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
regulation of cell population proliferation  (IMP)
regulation of protein complex stability  (IMP)
regulation of protein stability  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
roof of mouth development  (IGI)
semicircular canal morphogenesis  (IMP)
sinoatrial node cell development  (IMP,ISO)
skeletal system development  (ISO,ISS)
smooth muscle cell differentiation  (IGI)
specification of animal organ position  (IDA)
stem cell population maintenance  (IMP)
stem cell proliferation  (IMP)
ureteric peristalsis  (IGI)
ventricular septum morphogenesis  (IMP)

Cellular Component
chromatin  (IBA)
cilium  (IDA)
nucleus  (IBA,IDA,ISO,ISS)
transcription regulator complex  (IPI)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cardiac jelly morphology  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal clitoris morphology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal embryonic autopod plate morphology  (IAGP)
abnormal eye morphology  (IEA)
abnormal female reproductive system morphology  (IAGP)
abnormal fetal atrioventricular canal morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart looping  (IAGP)
abnormal hindlimb morphology  (IAGP)
abnormal hindlimb zeugopod morphology  (IAGP)
abnormal impulse conducting system conduction  (IAGP)
abnormal inferior vena cava morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal limb morphology  (IAGP)
abnormal lymph node morphology  (IEA)
abnormal mammary gland bud morphology  (IAGP)
abnormal mammary gland development  (IAGP)
abnormal mammary gland embryonic development  (IAGP)
abnormal P wave  (IAGP)
abnormal palatal shelf fusion at midline  (IAGP)
abnormal pelvic girdle bone morphology  (IAGP)
abnormal QRS complex  (IAGP)
abnormal retina blood vessel morphology  (IEA)
abnormal retina vasculature morphology  (IEA)
abnormal sinoatrial node morphology  (IAGP)
abnormal sinus arrhythmia  (IAGP)
abnormal ulna morphology  (IAGP)
abnormal vagina orifice morphology  (IAGP)
abnormal visceral yolk sac endoderm morphology  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
absent atrioventricular cushions  (IAGP)
absent carpal bone  (IAGP)
absent fibula  (IAGP)
absent mammary gland  (IAGP)
absent metacarpal bones  (IAGP)
absent P wave  (IAGP)
absent PR interval  (IAGP)
absent tarsus bones  (IAGP)
absent ulna  (IAGP)
absent vitelline blood vessels  (IAGP)
atrioventricular block  (IAGP)
cleft secondary palate  (IAGP)
decreased body size  (IAGP)
decreased heart rate  (IAGP)
decreased locomotor activity  (IEA)
decreased sinoatrial node size  (IAGP)
delayed heart looping  (IAGP)
edema  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality prior to organogenesis  (IEA)
embryonic lethality, complete penetrance  (IAGP)
embryonic lethality, incomplete penetrance  (IAGP)
eye hemorrhage  (IEA)
failure of heart looping  (IAGP)
increased cardiac muscle contractility  (IAGP)
increased circulating alkaline phosphatase level  (IEA)
increased heart rate variability  (IAGP)
irregular heartbeat  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
microphthalmia  (IEA)
no abnormal phenotype detected  (IAGP)
oligodactyly  (IAGP)
pale yolk sac  (IAGP)
pericardial edema  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
prolonged QRS complex duration  (IAGP)
reduced female fertility  (IAGP)
reduced male fertility  (IAGP)
short hindlimb  (IAGP)
shortened PR interval  (IAGP)
sinoatrial node hypoplasia  (IAGP)
sinus bradycardia  (IAGP)
small hindlimb buds  (IAGP)
small liver  (IAGP)
thin apical ectodermal ridge  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. The ulnar-mammary syndrome gene, Tbx3, is a direct target of the retinoic acid signaling pathway, which regulates its expression during mouse limb development. Ballim RD, etal., Mol Biol Cell. 2012 Jun;23(12):2362-72. doi: 10.1091/mbc.E11-09-0790. Epub 2012 Apr 25.
2. The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome. Bamshad M, etal., Am J Hum Genet. 1999 Jun;64(6):1550-62.
3. Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. Bamshad M, etal., Nat Genet 1997 Jul;16(3):311-5.
4. Estrogen receptor alpha supports cardiomyocytes indirectly through post-infarct cardiac c-kit+ cells. Brinckmann M, etal., J Mol Cell Cardiol. 2009 Jul;47(1):66-75. Epub 2009 Mar 31.
5. T-box Transcription Factor Tbx3 Contributes to Human Hepatocellular Carcinoma Cell Migration and Invasion by Repressing E-Cadherin Expression. Feng X, etal., Oncol Res. 2018 Jul 5;26(6):959-966. doi: 10.3727/096504017X15145624664031. Epub 2018 Jan 2.
6. Down-regulation of β-catenin and the associated migration ability by Taiwanin C in arecoline and 4-NQO-induced oral cancer cells via GSK-3β activation. Hsieh CH, etal., Mol Carcinog. 2017 Mar;56(3):1055-1067. doi: 10.1002/mc.22570. Epub 2016 Oct 4.
7. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
8. Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. Lachenmayer A, etal., Clin Cancer Res. 2012 Sep 15;18(18):4997-5007. doi: 10.1158/1078-0432.CCR-11-2322. Epub 2012 Jul 18.
9. Expression of TBX3 in Hepatocellular Carcinoma and Its Clinical Implication. Li Z, etal., Med Sci Monit. 2018 Dec 22;24:9324-9333. doi: 10.12659/MSM.909378.
10. TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis. Liang B, etal., J Hepatol. 2021 Jul;75(1):120-131. doi: 10.1016/j.jhep.2021.01.044. Epub 2021 Feb 10.
11. MGDs mouse GO annotations MGD data from the GO Consortium
12. MGD IEA MGD IEA
13. Tbx3 overexpression in human gastric cancer is correlated with advanced tumor stage and nodal status and promotes cancer cell growth and invasion. Miao ZF, etal., Virchows Arch. 2016 Nov;469(5):505-513. doi: 10.1007/s00428-016-2007-9. Epub 2016 Aug 24.
14. Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
15. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
17. Mouse MP Annotation Import Pipeline RGD automated import pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Overexpression of Tbx3 is correlated with Epithelial-Mesenchymal Transition phenotype and predicts poor prognosis of colorectal cancer. Shan ZZ, etal., Am J Cancer Res. 2014 Dec 15;5(1):344-53. eCollection 2015.
21. Proteomics success story. Towards early detection of breast and ovarian cancer: plasma proteomics as a tool to find novel markers. Souchelnytskyi S, etal., Proteomics. 2006 Sep;6 Suppl 2:65-8.
22. A combined analysis of genomic and primary protein structure defines the phylogenetic relationship of new members if the T-box family. Wattler S, etal., Genomics 1998 Feb 15;48(1):24-33.
23. [Inhibitory effect of Biejiajian pills on HepG2 cell xenograft growth and expression of β-catenin and Tbx3 in nude mice]. Wen B, etal., Nan Fang Yi Ke Da Xue Xue Bao. 2016 Feb;36(2):210-4.
Additional References at PubMed
PMID:1375456   PMID:7688225   PMID:7920656   PMID:8798150   PMID:8853987   PMID:8878690   PMID:8889548   PMID:8954725   PMID:9169414   PMID:9196325   PMID:9337408   PMID:10072792  
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11726608   PMID:11748239   PMID:12032820   PMID:12376101   PMID:12477932   PMID:12668638   PMID:12736212   PMID:14610273  
PMID:14723846   PMID:15136151   PMID:15158141   PMID:15255957   PMID:15297379   PMID:15385444   PMID:15459098   PMID:15618518   PMID:15843407   PMID:15901664   PMID:16140987   PMID:16141072  
PMID:16141073   PMID:16207751   PMID:16222716   PMID:16380715   PMID:16556915   PMID:16556916   PMID:16602821   PMID:16632597   PMID:16870172   PMID:16989801   PMID:17028893   PMID:17071745  
PMID:17173667   PMID:17199044   PMID:17234970   PMID:17239249   PMID:17265068   PMID:17460765   PMID:17473172   PMID:17519333   PMID:17588959   PMID:17609113   PMID:17668378   PMID:17698011  
PMID:18285513   PMID:18287559   PMID:18292603   PMID:18356246   PMID:18410737   PMID:18444963   PMID:18467625   PMID:18534921   PMID:18723448   PMID:18799693   PMID:18832392   PMID:19096026  
PMID:19115250   PMID:19140222   PMID:19166829   PMID:19498200   PMID:19576202   PMID:19592579   PMID:19765559   PMID:19769959   PMID:19877281   PMID:20025935   PMID:20059953   PMID:20110338  
PMID:20139965   PMID:20159597   PMID:20185795   PMID:20386744   PMID:20412781   PMID:20457925   PMID:20596014   PMID:20732316   PMID:20941780   PMID:21143873   PMID:21189255   PMID:21256124  
PMID:21266775   PMID:21267068   PMID:21282332   PMID:21304516   PMID:21454626   PMID:21455926   PMID:21538160   PMID:21589869   PMID:21640717   PMID:21731673   PMID:21757651   PMID:21795542  
PMID:21867776   PMID:21873635   PMID:21924257   PMID:21983003   PMID:22039763   PMID:22116619   PMID:22116936   PMID:22130515   PMID:22164283   PMID:22174793   PMID:22203979   PMID:22223620  
PMID:22419669   PMID:22438573   PMID:22522080   PMID:22543974   PMID:22706305   PMID:22711520   PMID:22921202   PMID:22988430   PMID:23201021   PMID:23283339   PMID:23341776   PMID:23369715  
PMID:23473983   PMID:23506836   PMID:23584530   PMID:23624936   PMID:23633963   PMID:23661717   PMID:23674600   PMID:23743334   PMID:23844108   PMID:23936153   PMID:24068957   PMID:24143284  
PMID:24146773   PMID:24260306   PMID:24319661   PMID:24336466   PMID:24394418   PMID:24425205   PMID:24449835   PMID:24472544   PMID:24623077   PMID:24680892   PMID:24705356   PMID:24831012  
PMID:24859004   PMID:24876127   PMID:24924197   PMID:24927531   PMID:24963028   PMID:25053429   PMID:25145359   PMID:25166052   PMID:25336743   PMID:25343378   PMID:25389758   PMID:25453830  
PMID:25487574   PMID:25488669   PMID:25552398   PMID:25599332   PMID:25613430   PMID:25792196   PMID:25859222   PMID:26095607   PMID:26138475   PMID:26193633   PMID:26238476   PMID:26243870  
PMID:26321631   PMID:26417040   PMID:26459221   PMID:26493106   PMID:26581094   PMID:26651606   PMID:26764381   PMID:26988119   PMID:27046536   PMID:27076431   PMID:27180262   PMID:27253890  
PMID:27491074   PMID:27518902   PMID:27720610   PMID:27856909   PMID:28069742   PMID:28205312   PMID:28361920   PMID:28807898   PMID:28894084   PMID:29031500   PMID:29107716   PMID:29409032  
PMID:29420474   PMID:29445148   PMID:29853617   PMID:30042181   PMID:30201295   PMID:30291164   PMID:30292786   PMID:30478225   PMID:30595499   PMID:30630509   PMID:30765799   PMID:30840660  
PMID:30936179   PMID:31077711   PMID:31175693   PMID:31306714   PMID:31320323   PMID:31578032   PMID:31591643   PMID:31688894   PMID:31836710   PMID:31870435   PMID:31896583   PMID:32098917  
PMID:32290757   PMID:32672536   PMID:32675240   PMID:32694784   PMID:32808927   PMID:33443158   PMID:33444816   PMID:33545088   PMID:33568475   PMID:33600763   PMID:33795231   PMID:33869166  
PMID:33887179   PMID:34062094   PMID:34906355   PMID:35252804   PMID:35506352   PMID:35552394   PMID:35650438   PMID:35905011   PMID:35951005   PMID:36074819   PMID:36255053   PMID:36383654  
PMID:36521641   PMID:36709241   PMID:36709857   PMID:36719070   PMID:36923312   PMID:36941249   PMID:36941669   PMID:37081156   PMID:37126314   PMID:37227818   PMID:37442233   PMID:37878207  
PMID:38355793   PMID:38750011   PMID:38828908   PMID:38909034   PMID:38968109  


Genomics

Comparative Map Data
Tbx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395119,808,600 - 119,822,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5119,808,734 - 119,822,789 (+)EnsemblGRCm39 Ensembl
GRCm385119,670,534 - 119,684,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5119,670,669 - 119,684,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv375120,120,678 - 120,134,610 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365119,931,286 - 119,945,218 (+)NCBIMGSCv36mm8
Celera5116,764,719 - 116,778,686 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map560.34NCBI
TBX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812114,670,255 - 114,684,175 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12114,670,255 - 114,684,175 (-)EnsemblGRCh38hg38GRCh38
GRCh3712115,108,060 - 115,121,980 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612113,592,442 - 113,606,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412113,570,778 - 113,584,689NCBI
Celera12114,735,560 - 114,749,458 (-)NCBICelera
Cytogenetic Map12q24.21NCBI
HuRef12112,116,904 - 112,130,825 (-)NCBIHuRef
CHM1_112115,075,996 - 115,089,899 (-)NCBICHM1_1
T2T-CHM13v2.012114,647,343 - 114,661,251 (-)NCBIT2T-CHM13v2.0
Tbx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81242,540,378 - 42,555,490 (-)NCBIGRCr8
mRatBN7.21236,879,924 - 36,894,849 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1236,881,445 - 36,893,708 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1238,058,977 - 38,070,162 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01238,672,813 - 38,684,003 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01237,725,254 - 37,736,439 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01242,479,518 - 42,494,588 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1242,480,560 - 42,492,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01244,326,928 - 44,342,670 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41238,155,494 - 38,166,670 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11238,018,881 - 38,030,058 (-)NCBI
Celera1238,555,497 - 38,566,664 (-)NCBICelera
Cytogenetic Map12q16NCBI
Tbx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545515,988,663 - 16,000,063 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545515,988,153 - 16,000,156 (+)NCBIChiLan1.0ChiLan1.0
TBX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210122,724,799 - 122,741,407 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112122,721,192 - 122,735,426 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012112,240,050 - 112,254,299 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112115,618,420 - 115,632,327 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12115,620,002 - 115,631,316 (-)Ensemblpanpan1.1panPan2
TBX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12611,694,885 - 11,709,594 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2611,696,565 - 11,708,918 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2611,753,296 - 11,767,965 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02611,953,157 - 11,967,841 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2611,954,731 - 11,966,470 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12611,914,521 - 11,929,199 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02611,977,110 - 11,991,787 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02612,026,728 - 12,041,404 (-)NCBIUU_Cfam_GSD_1.0
Tbx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118152,235,738 - 152,248,370 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365587,230,668 - 7,244,361 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365587,230,361 - 7,243,651 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1437,582,822 - 37,596,766 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11437,582,704 - 37,596,767 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21440,012,569 - 40,026,314 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111109,952,100 - 109,966,328 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11109,952,054 - 109,965,065 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037135,142,552 - 135,156,757 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474718,128,028 - 18,142,451 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474718,128,003 - 18,142,366 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tbx3
797 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1803
Count of miRNA genes:531
Interacting mature miRNAs:655
Transcripts:ENSMUST00000018748, ENSMUST00000079719, ENSMUST00000121021, ENSMUST00000145647, ENSMUST00000154680
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5114021753129632606Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108762509126882944Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse

Markers in Region
UniSTS:235919  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385119,675,771 - 119,675,861UniSTSGRCm38
MGSCv375120,125,780 - 120,125,870UniSTSGRCm37
Celera5116,769,819 - 116,769,909UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
D5Ertd189e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385119,683,739 - 119,683,955UniSTSGRCm38
MGSCv375120,133,748 - 120,133,964UniSTSGRCm37
Celera5116,777,831 - 116,778,045UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Tbx3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv375120,124,230 - 120,125,665UniSTSGRCm37
Celera5116,768,272 - 116,769,704UniSTS
Cytogenetic Map5FUniSTS
cM Map565.0UniSTS
Tbx3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385119,674,221 - 119,675,656UniSTSGRCm38
MGSCv375120,124,230 - 120,125,665UniSTSGRCm37
Celera5116,768,272 - 116,769,704UniSTS
Cytogenetic Map5FUniSTS
Tbx3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5FUniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA543734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF429310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB054411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB694449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB728182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ216213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U15567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U57328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000018748   ⟹   ENSMUSP00000018748
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5119,809,083 - 119,822,789 (+)Ensembl
GRCm38.p6 Ensembl5119,671,018 - 119,684,724 (+)Ensembl
Ensembl Acc Id: ENSMUST00000079719   ⟹   ENSMUSP00000078657
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5119,808,734 - 119,822,626 (+)Ensembl
GRCm38.p6 Ensembl5119,670,669 - 119,684,561 (+)Ensembl
Ensembl Acc Id: ENSMUST00000121021   ⟹   ENSMUSP00000112519
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5119,808,927 - 119,822,789 (+)Ensembl
GRCm38.p6 Ensembl5119,670,862 - 119,684,724 (+)Ensembl
Ensembl Acc Id: ENSMUST00000145647
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5119,813,510 - 119,818,695 (+)Ensembl
GRCm38.p6 Ensembl5119,675,445 - 119,680,630 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154680
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5119,818,314 - 119,818,897 (+)Ensembl
GRCm38.p6 Ensembl5119,680,249 - 119,680,832 (+)Ensembl
Ensembl Acc Id: ENSMUST00000202034
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5119,808,734 - 119,811,728 (+)Ensembl
GRCm38.p6 Ensembl5119,670,669 - 119,673,663 (+)Ensembl
RefSeq Acc Id: NM_011535   ⟹   NP_035665
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,809,298 - 119,822,789 (+)NCBI
GRCm385119,671,233 - 119,684,724 (+)NCBI
MGSCv375120,120,678 - 120,134,610 (+)RGD
Celera5116,764,912 - 116,778,809 (+)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_198052   ⟹   NP_932169
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,808,927 - 119,822,789 (+)NCBI
GRCm385119,670,862 - 119,684,724 (+)NCBI
MGSCv375120,120,678 - 120,134,610 (+)RGD
Celera5116,764,912 - 116,778,809 (+)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530276   ⟹   XP_006530339
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395119,808,600 - 119,822,789 (+)NCBI
GRCm385119,670,534 - 119,684,724 (+)NCBI
Sequence:
RefSeq Acc Id: NP_035665   ⟸   NM_011535
- Peptide Label: isoform 1
- UniProtKB: Q60708 (UniProtKB/Swiss-Prot),   E9QM97 (UniProtKB/Swiss-Prot),   Q8BWH7 (UniProtKB/Swiss-Prot),   P70324 (UniProtKB/Swiss-Prot),   Q3ULL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_932169   ⟸   NM_198052
- Peptide Label: isoform 2
- UniProtKB: Q4VA43 (UniProtKB/TrEMBL),   Q3U043 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530339   ⟸   XM_006530276
- Peptide Label: isoform X1
- UniProtKB: Q60708 (UniProtKB/Swiss-Prot),   E9QM97 (UniProtKB/Swiss-Prot),   Q8BWH7 (UniProtKB/Swiss-Prot),   P70324 (UniProtKB/Swiss-Prot),   Q3ULL3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000078657   ⟸   ENSMUST00000079719
Ensembl Acc Id: ENSMUSP00000112519   ⟸   ENSMUST00000121021
Ensembl Acc Id: ENSMUSP00000018748   ⟸   ENSMUST00000018748
Protein Domains
T-box   T-box transcription factor 2/3 repressor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70324-F1-model_v2 AlphaFold P70324 1-741 view protein structure

Promoters
RGD ID:6887840
Promoter ID:EPDNEW_M7371
Type:initiation region
Name:Tbx3_1
Description:Mus musculus T-box 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7372  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385119,671,018 - 119,671,078EPDNEW
RGD ID:6887842
Promoter ID:EPDNEW_M7372
Type:multiple initiation site
Name:Tbx3_2
Description:Mus musculus T-box 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M7371  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385119,671,693 - 119,671,753EPDNEW
RGD ID:6838478
Promoter ID:MM_KWN:43796
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000121021,   NM_198052,   OTTMUST00000073569
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365120,119,931 - 120,122,307 (+)MPROMDB
RGD ID:6838479
Promoter ID:MM_KWN:43798
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:OTTMUST00000073571
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365120,124,706 - 120,125,206 (+)MPROMDB
RGD ID:6838480
Promoter ID:MM_KWN:43799
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000073572
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365120,130,361 - 120,130,861 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98495 AgrOrtholog
Ensembl Genes ENSMUSG00000018604 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000018748 ENTREZGENE
  ENSMUST00000018748.9 UniProtKB/Swiss-Prot
  ENSMUST00000079719.11 UniProtKB/Swiss-Prot
  ENSMUST00000121021 ENTREZGENE
  ENSMUST00000121021.8 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-box_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-box_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBX2_3_RD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_Brachyury UniProtKB/TrEMBL
  TF_T-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21386 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98495 ENTREZGENE
NCBI Gene 21386 ENTREZGENE
PANTHER PTHR11267 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T-BOX TRANSCRIPTION FACTOR TBX3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam T-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBX2-3_RD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tbx3 PhenoGen
PRINTS BRACHYURY UniProtKB/TrEMBL
  TBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBOX_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9QM97 ENTREZGENE
  P70324 ENTREZGENE
  Q3U043 ENTREZGENE, UniProtKB/TrEMBL
  Q3ULL3 ENTREZGENE, UniProtKB/TrEMBL
  Q4VA43 ENTREZGENE, UniProtKB/TrEMBL
  Q60708 ENTREZGENE
  Q8BG45_MOUSE UniProtKB/TrEMBL
  Q8BJW3_MOUSE UniProtKB/TrEMBL
  Q8BU76_MOUSE UniProtKB/TrEMBL
  Q8BWH7 ENTREZGENE
  Q8CJ82_MOUSE UniProtKB/TrEMBL
  TBX3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary E9QM97 UniProtKB/Swiss-Prot
  Q60708 UniProtKB/Swiss-Prot
  Q8BWH7 UniProtKB/Swiss-Prot