Plcb2 (phospholipase C, beta 2) - Rat Genome Database

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Gene: Plcb2 (phospholipase C, beta 2) Mus musculus
Analyze
Symbol: Plcb2
Name: phospholipase C, beta 2
RGD ID: 1557476
MGI Page MGI
Description: Predicted to enable G-protein beta/gamma-subunit complex binding activity; phosphatidylinositol phospholipase C activity; and phospholipid binding activity. Acts upstream of or within sensory perception of bitter taste. Located in cytoplasm. Is active in neuronal dense core vesicle. Is expressed in several structures, including early conceptus; genitourinary system; gut; immune system; and liver. Orthologous to human PLCB2 (phospholipase C beta 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; AI550384; B230205M18Rik; B230399N12; phosphoinositide phospholipase C-beta-2; phospholipase C-beta-2; PLC-beta-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392118,535,484 - 118,559,140 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2118,537,998 - 118,558,919 (-)EnsemblGRCm39 Ensembl
GRCm382118,705,003 - 118,728,661 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2118,707,517 - 118,728,438 (-)EnsemblGRCm38mm10GRCm38
MGSCv372118,533,253 - 118,554,174 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362118,398,958 - 118,419,879 (-)NCBIMGSCv36mm8
Celera2119,861,823 - 119,882,734 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme? Drin G and Scarlata S, Cell Signal. 2007 Jul;19(7):1383-92. Epub 2007 Apr 29.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Regulation of phosphoinositide-specific phospholipase C. Rhee SG Annu Rev Biochem. 2001;70:281-312.
10. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Zhang Y, etal., Cell 2003 Feb 7;112(3):293-301.
Additional References at PubMed
PMID:2033248   PMID:8672127   PMID:8739298   PMID:8889548   PMID:9223297   PMID:9305844   PMID:9753089   PMID:10349636   PMID:10609087   PMID:10669417   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:12466851   PMID:12477932   PMID:14657398   PMID:14681479   PMID:14695357   PMID:15174099   PMID:15705797   PMID:15759003   PMID:15782199   PMID:15926917   PMID:16135743  
PMID:16141072   PMID:16141073   PMID:16394244   PMID:17634444   PMID:17675482   PMID:17921328   PMID:18079968   PMID:18287559   PMID:19071193   PMID:19343206   PMID:19647226   PMID:19850892  
PMID:20591207   PMID:20668922   PMID:20689832   PMID:20871625   PMID:20965149   PMID:21321602   PMID:21606356   PMID:21677750   PMID:21688022   PMID:21873635   PMID:22172670   PMID:22728827  
PMID:23010799   PMID:23295235   PMID:23407495   PMID:23478264   PMID:24194600   PMID:24367558   PMID:24428937   PMID:24843119   PMID:25256039   PMID:25940069   PMID:25959047   PMID:26046438  
PMID:26079812   PMID:26468229   PMID:26582648   PMID:27626380   PMID:27704316   PMID:27910949   PMID:28124257   PMID:28578927   PMID:30270038   PMID:30691513   PMID:30720883   PMID:30765691  
PMID:31268747   PMID:31286141   PMID:31980480   PMID:32098606   PMID:32259485   PMID:32294408   PMID:32325033   PMID:32960355   PMID:34009125   PMID:35861069   PMID:35987808   PMID:37045597  


Genomics

Comparative Map Data
Plcb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392118,535,484 - 118,559,140 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2118,537,998 - 118,558,919 (-)EnsemblGRCm39 Ensembl
GRCm382118,705,003 - 118,728,661 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2118,707,517 - 118,728,438 (-)EnsemblGRCm38mm10GRCm38
MGSCv372118,533,253 - 118,554,174 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362118,398,958 - 118,419,879 (-)NCBIMGSCv36mm8
Celera2119,861,823 - 119,882,734 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.43NCBI
PLCB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381540,284,256 - 40,307,935 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1540,278,176 - 40,307,935 (-)EnsemblGRCh38hg38GRCh38
GRCh371540,580,110 - 40,600,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,367,390 - 38,387,466 (-)NCBINCBI36Build 36hg18NCBI36
Build 341538,367,401 - 38,387,330NCBI
Celera1517,346,090 - 17,366,157 (-)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1517,423,058 - 17,443,532 (-)NCBIHuRef
CHM1_11540,700,041 - 40,720,115 (-)NCBICHM1_1
T2T-CHM13v2.01538,091,173 - 38,114,815 (-)NCBIT2T-CHM13v2.0
Plcb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83126,134,925 - 126,158,303 (-)NCBIGRCr8
mRatBN7.23105,683,676 - 105,704,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3105,684,815 - 105,704,302 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3109,357,684 - 109,377,152 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03117,953,248 - 117,972,712 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03115,613,610 - 115,633,075 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03110,497,760 - 110,517,563 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,498,114 - 110,517,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03117,038,677 - 117,058,132 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,203,524 - 105,223,342 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13105,099,951 - 105,119,770 (-)NCBI
Celera3104,599,222 - 104,618,601 (-)NCBICelera
Cytogenetic Map3q35NCBI
Plcb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554167,218,417 - 7,240,739 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554167,221,326 - 7,240,743 (-)NCBIChiLan1.0ChiLan1.0
PLCB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21629,518,245 - 29,541,893 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11533,669,673 - 33,693,337 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01519,218,329 - 19,241,977 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11537,476,699 - 37,496,813 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1537,476,699 - 37,496,813 (-)Ensemblpanpan1.1panPan2
PLCB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1307,472,208 - 7,493,106 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl307,472,413 - 7,492,801 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha307,526,161 - 7,547,075 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0307,598,044 - 7,618,970 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl307,594,683 - 7,619,120 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1307,522,589 - 7,543,490 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0307,628,543 - 7,649,438 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0307,757,123 - 7,778,226 (-)NCBIUU_Cfam_GSD_1.0
Plcb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864085,908,907 - 85,928,377 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364713,756,970 - 3,776,392 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364713,756,978 - 3,776,452 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1131,005,408 - 131,028,689 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11131,005,408 - 131,031,864 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21146,286,447 - 146,302,118 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLCB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12642,706,462 - 42,727,516 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2642,707,625 - 42,727,145 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604898,236,858 - 98,257,092 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248047,591,844 - 7,612,645 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248047,593,956 - 7,612,860 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plcb2
498 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1855
Count of miRNA genes:614
Interacting mature miRNAs:760
Transcripts:ENSMUST00000006415, ENSMUST00000102524, ENSMUST00000126907, ENSMUST00000127248, ENSMUST00000129153, ENSMUST00000159756
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
1300798Actre3_mactivity response to ethanol 3 (mouse)Not determined2112024987128173821Mouse
1301415Actre4_mactivity response to ethanol 4 (mouse)Not determined2112024987128173821Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
13506762Tbvq2_mtrabecular bone volume QTL 2 (mouse)2115430481124741920Mouse
1558825Aabpr_maberrant activation of B cell proliferation (mouse)Not determined2116033229122207534Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
12904007Cfq7_mconditioned fear QTL 7 (mouse)2118356772125048872Mouse

Markers in Region
AI550384  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382118,707,815 - 118,707,904UniSTSGRCm38
MGSCv372118,533,551 - 118,533,640UniSTSGRCm37
Celera2119,862,121 - 119,862,210UniSTS
Cytogenetic Map2E5UniSTS
cM Map267.0UniSTS
Whitehead/MRC_RH21511.0UniSTS
Plcb2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382118,713,833 - 118,714,693UniSTSGRCm38
Celera2119,868,141 - 119,869,016UniSTS
Cytogenetic Map2E5UniSTS
cM Map259.43UniSTS
Plcb2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E5UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001290790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF022802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL772255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY902324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB620972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB635904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE991828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000006415
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,544,714 - 118,558,872 (-)Ensembl
GRCm38.p6 Ensembl2118,714,233 - 118,728,391 (-)Ensembl
RefSeq Acc Id: ENSMUST00000102524   ⟹   ENSMUSP00000099583
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,537,998 - 118,558,919 (-)Ensembl
GRCm38.p6 Ensembl2118,707,517 - 118,728,438 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126907
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,539,180 - 118,540,222 (-)Ensembl
GRCm38.p6 Ensembl2118,708,699 - 118,709,741 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127248
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,541,298 - 118,544,585 (-)Ensembl
GRCm38.p6 Ensembl2118,710,817 - 118,714,104 (-)Ensembl
RefSeq Acc Id: ENSMUST00000129153
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,538,661 - 118,541,851 (-)Ensembl
GRCm38.p6 Ensembl2118,708,180 - 118,711,370 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159756   ⟹   ENSMUSP00000124364
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,538,477 - 118,558,840 (-)Ensembl
GRCm38.p6 Ensembl2118,707,996 - 118,728,359 (-)Ensembl
RefSeq Acc Id: NM_001290790   ⟹   NP_001277719
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,537,998 - 118,558,919 (-)NCBI
GRCm382118,707,517 - 118,728,438 (-)NCBI
Celera2119,861,823 - 119,882,734 (-)NCBI
Sequence:
RefSeq Acc Id: NM_177568   ⟹   NP_808236
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,537,998 - 118,558,919 (-)NCBI
GRCm382118,707,517 - 118,728,438 (-)NCBI
MGSCv372118,533,253 - 118,554,174 (-)RGD
Celera2119,861,823 - 119,882,734 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006498935   ⟹   XP_006498998
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,547,893 - 118,559,138 (-)NCBI
GRCm382118,717,417 - 118,728,659 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017316357   ⟹   XP_017171846
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,535,484 - 118,559,138 (-)NCBI
GRCm382118,705,003 - 118,728,659 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017316359   ⟹   XP_017171848
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,543,648 - 118,559,139 (-)NCBI
GRCm382118,713,167 - 118,728,660 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159566   ⟹   XP_036015459
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,546,170 - 118,559,140 (-)NCBI
Sequence:
RefSeq Acc Id: NP_808236   ⟸   NM_177568
- Peptide Label: isoform a
- UniProtKB: Q3TER8 (UniProtKB/Swiss-Prot),   Q2M4J1 (UniProtKB/Swiss-Prot),   Q8BI81 (UniProtKB/Swiss-Prot),   A3KGF7 (UniProtKB/Swiss-Prot),   B7ZNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498998   ⟸   XM_006498935
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001277719   ⟸   NM_001290790
- Peptide Label: isoform b
- UniProtKB: E9PYI3 (UniProtKB/TrEMBL),   B7ZNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017171846   ⟸   XM_017316357
- Peptide Label: isoform X1
- UniProtKB: B7ZNI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017171848   ⟸   XM_017316359
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000124364   ⟸   ENSMUST00000159756
RefSeq Acc Id: ENSMUSP00000099583   ⟸   ENSMUST00000102524
RefSeq Acc Id: XP_036015459   ⟸   XM_036159566
- Peptide Label: isoform X3
Protein Domains
C2   PI-PLC X-box   PI-PLC Y-box   PLC-beta PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A3KGF7-F1-model_v2 AlphaFold A3KGF7 1-1181 view protein structure

Promoters
RGD ID:6832077
Promoter ID:MM_KWN:31182
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Lung
Transcripts:OTTMUST00000036441,   OTTMUST00000036442
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362118,536,674 - 118,537,174 (-)MPROMDB
RGD ID:6832074
Promoter ID:MM_KWN:31185
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:ENSMUST00000077829,   NM_177568,   OTTMUST00000036438
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362118,554,226 - 118,555,062 (-)MPROMDB
RGD ID:6878304
Promoter ID:EPDNEW_M2603
Type:initiation region
Name:Plcb2_1
Description:Mus musculus phospholipase C, beta 2 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382118,728,391 - 118,728,451EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107465 AgrOrtholog
Ensembl Genes ENSMUSG00000040061 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000102524 ENTREZGENE
  ENSMUST00000102524.8 UniProtKB/Swiss-Prot
  ENSMUST00000159756 ENTREZGENE
  ENSMUST00000159756.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1230.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-beta2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-beta_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-beta_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-beta_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC_EF-hand-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLCbeta2_EF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18796 UniProtKB/Swiss-Prot
MGD MGI:107465 ENTREZGENE
NCBI Gene 18796 ENTREZGENE
PANTHER PTHR10336 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10336:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EF-hand_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-beta_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Plcb2 PhenoGen
PIRSF PLC-beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PIPLC_X_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PLCXc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLCYc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP C-terminal domain of PLC-beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A3KGF7 ENTREZGENE
  B7ZNI1 ENTREZGENE, UniProtKB/TrEMBL
  E9PYI3 ENTREZGENE, UniProtKB/TrEMBL
  PLCB2_MOUSE UniProtKB/Swiss-Prot
  Q2M4J1 ENTREZGENE
  Q3TER8 ENTREZGENE
  Q3V3V2_MOUSE UniProtKB/TrEMBL
  Q8BI81 ENTREZGENE
  Q9Z2T4_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q2M4J1 UniProtKB/Swiss-Prot
  Q3TER8 UniProtKB/Swiss-Prot
  Q8BI81 UniProtKB/Swiss-Prot