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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sppl2a | Mouse | Immunodeficiency 86 | | ISO | SPPL2A (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sppl2a | Mouse | Immunodeficiency 86 | | ISO | SPPL2A (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
2. | MGDs mouse GO annotations | MGD data from the GO Consortium |
3. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
4. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:7671812 | PMID:8889548 | PMID:10349636 | PMID:10922068 | PMID:11042159 | PMID:11076861 | PMID:12477932 | PMID:14610273 | PMID:15489334 | PMID:16141072 | PMID:16141073 | PMID:18287559 |
PMID:18799693 | PMID:21267068 | PMID:21873635 | PMID:21896273 | PMID:23267013 | PMID:23267015 | PMID:23267016 | PMID:23426979 | PMID:24492962 | PMID:24872421 | PMID:26157172 | PMID:26987812 |
PMID:28550201 | PMID:30127434 | PMID:30733281 | PMID:30819724 | PMID:31146259 | PMID:32325033 | PMID:33239420 | PMID:36047592 |
Sppl2a (Mus musculus - house mouse) |
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SPPL2A (Homo sapiens - human) |
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Sppl2a (Rattus norvegicus - Norway rat) |
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Sppl2a (Chinchilla lanigera - long-tailed chinchilla) |
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SPPL2A (Pan paniscus - bonobo/pygmy chimpanzee) |
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SPPL2A (Canis lupus familiaris - dog) |
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Sppl2a (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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SPPL2A (Sus scrofa - pig) |
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SPPL2A (Chlorocebus sabaeus - green monkey) |
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Sppl2a (Heterocephalus glaber - naked mole-rat) |
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Variants in Sppl2a
2155 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
RH118253 |
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UniSTS:234518 |
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RefSeq Transcripts | NM_023220 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_036162455 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_036162456 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_036162457 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_004940682 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_004940683 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_004940684 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_004940685 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_004940686 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XR_004940687 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB041547 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AI853709 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK008294 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK008320 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK008328 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK047349 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK080421 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK081953 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK150366 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK150546 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK152512 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK152714 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AK155011 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AL732330 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AL928836 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC016267 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC026578 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH466519 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSMUST00000028844 ⟹ ENSMUSP00000028844 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSMUST00000125592 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSMUST00000143700 ⟹ ENSMUSP00000119064 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_023220 ⟹ NP_075709 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_036162455 ⟹ XP_036018348 | ||||||||
Type: | CODING | ||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_036162456 ⟹ XP_036018349 | ||||||||
Type: | CODING | ||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_036162457 ⟹ XP_036018350 | ||||||||
Type: | CODING | ||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XR_004940682 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XR_004940683 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XR_004940684 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XR_004940685 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XR_004940686 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XR_004940687 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_075709 | (Get FASTA) | NCBI Sequence Viewer |
XP_036018348 | (Get FASTA) | NCBI Sequence Viewer | |
XP_036018349 | (Get FASTA) | NCBI Sequence Viewer | |
XP_036018350 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH26578 | (Get FASTA) | NCBI Sequence Viewer |
BAA95032 | (Get FASTA) | NCBI Sequence Viewer | |
BAB25583 | (Get FASTA) | NCBI Sequence Viewer | |
BAB25599 | (Get FASTA) | NCBI Sequence Viewer | |
BAB25606 | (Get FASTA) | NCBI Sequence Viewer | |
EDL28169 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSMUSP00000028844 | ||
ENSMUSP00000028844.5 | |||
ENSMUSP00000119064.2 | |||
GenBank Protein | Q9JJF9 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_075709 ⟸ NM_023220 |
- Peptide Label: | precursor |
- UniProtKB: | Q9JJF9 (UniProtKB/Swiss-Prot), A2AI51 (UniProtKB/Swiss-Prot), Q8R354 (UniProtKB/Swiss-Prot) |
- Sequence: |
Ensembl Acc Id: | ENSMUSP00000119064 ⟸ ENSMUST00000143700 |
Ensembl Acc Id: | ENSMUSP00000028844 ⟸ ENSMUST00000028844 |
RefSeq Acc Id: | XP_036018348 ⟸ XM_036162455 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_036018349 ⟸ XM_036162456 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_036018350 ⟸ XM_036162457 |
- Peptide Label: | isoform X2 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9JJF9-F1-model_v2 | AlphaFold | Q9JJF9 | 1-523 | view protein structure |
RGD ID: | 6830558 | ||||||||
Promoter ID: | MM_KWN:31568 | ||||||||
Type: | Non-CpG | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | MPROMDB | ||||||||
Tissues & Cell Lines: | BoneMarrow_2Hour, BoneMarrow_4Hour, Kidney, Liver | ||||||||
Transcripts: | UC008MEJ.1 | ||||||||
Position: |
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RGD ID: | 6832348 | ||||||||
Promoter ID: | MM_KWN:31569 | ||||||||
Type: | Non-CpG | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | MPROMDB | ||||||||
Tissues & Cell Lines: | BoneMarrow_2Hour, BoneMarrow_4Hour | ||||||||
Transcripts: | OTTMUST00000038174 | ||||||||
Position: |
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RGD ID: | 6832349 | ||||||||
Promoter ID: | MM_KWN:31570 | ||||||||
Type: | Non-CpG | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | MPROMDB | ||||||||
Tissues & Cell Lines: | BoneMarrow_4Hour | ||||||||
Transcripts: | OTTMUST00000037954 | ||||||||
Position: |
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RGD ID: | 6830566 | ||||||||
Promoter ID: | MM_KWN:31571 | ||||||||
Type: | CpG-Island | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | MPROMDB | ||||||||
Tissues & Cell Lines: | 3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen | ||||||||
Transcripts: | ENSMUST00000110397, OTTMUST00000037953 | ||||||||
Position: |
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RGD ID: | 6878616 | ||||||||
Promoter ID: | EPDNEW_M2759 | ||||||||
Type: | initiation region | ||||||||
Name: | Sppl2a_1 | ||||||||
Description: | Mus musculus signal peptide peptidase like 2A , mRNA. | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_M2760 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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RGD ID: | 6878618 | ||||||||
Promoter ID: | EPDNEW_M2760 | ||||||||
Type: | initiation region | ||||||||
Name: | Sppl2a_2 | ||||||||
Description: | Mus musculus signal peptide peptidase like 2A , mRNA. | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_M2759 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | MGI:1913802 | AgrOrtholog |
Ensembl Genes | ENSMUSG00000027366 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Transcript | ENSMUST00000028844 | ENTREZGENE |
ENSMUST00000028844.11 | UniProtKB/Swiss-Prot | |
ENSMUST00000143700.2 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.50.30.30 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | PA_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PA_domain | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Peptidase_A22B_SPP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Preselin/SPP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | mmu:66552 | UniProtKB/Swiss-Prot |
MGD | MGI:1913802 | ENTREZGENE |
NCBI Gene | 66552 | ENTREZGENE |
PANTHER | PTHR12174 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR12174:SF34 | UniProtKB/TrEMBL, UniProtKB/Swiss-Prot | |
Pfam | Peptidase_A22B | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PF02225 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Sppl2a | PhenoGen |
SMART | PSN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | PA domain | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A2AI51 | ENTREZGENE |
F6RJQ8_MOUSE | UniProtKB/TrEMBL | |
Q8R354 | ENTREZGENE | |
Q9CPY9_MOUSE | UniProtKB/TrEMBL | |
Q9CVG0_MOUSE | UniProtKB/TrEMBL | |
Q9JJF9 | ENTREZGENE, UniProtKB/Swiss-Prot | |
UniProt Secondary | A2AI51 | UniProtKB/Swiss-Prot |
Q8R354 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2012-11-15 | Sppl2a | signal peptide peptidase like 2A | 2010106G01Rik | RIKEN cDNA 2010106G01 gene | Symbol and/or name change | 5135510 | APPROVED |