Atg3 (autophagy related 3) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Atg3 (autophagy related 3) Mus musculus
Analyze
Symbol: Atg3
Name: autophagy related 3
RGD ID: 1557224
MGI Page MGI
Description: Enables Atg12 transferase activity and Atg8-family ligase activity. Involved in autophagosome assembly; mitochondrial fragmentation involved in apoptotic process; and regulation of cilium assembly. Acts upstream of or within macroautophagy and negative regulation of phagocytosis. Predicted to be part of Atg12-Atg5-Atg16 complex and cytoplasmic ubiquitin ligase complex. Predicted to be active in cytosol and phagophore assembly site. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human ATG3 (autophagy related 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610016C12Rik; AP; APG3; APG3 autophagy 3-like; APG3-like; Apg3l; Atg3l; autophagy Apg3p/Aut1p-like; autophagy-related 3; autophagy-related 3-like; autophagy-related protein 3; PC3-9; PC3-96; ubiquitin-like-conjugating enzyme ATG3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm18389  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391644,979,192 - 45,008,901 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1644,979,148 - 45,008,901 (+)EnsemblGRCm39 Ensembl
GRCm381645,158,829 - 45,188,538 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1645,158,785 - 45,188,538 (+)EnsemblGRCm38mm10GRCm38
MGSCv371645,158,942 - 45,188,651 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361645,078,161 - 45,107,870 (+)NCBIMGSCv36mm8
Celera1645,552,434 - 45,582,081 (+)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1629.45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-tribromophenol  (ISO)
2-bromohexadecanoic acid  (ISO)
2-deoxy-D-glucose  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (ISO)
acrylamide  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
amphotericin B  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP)
artesunate  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfide  (ISO)
cantharidin  (ISO)
captan  (EXP)
carbon nanotube  (EXP)
choline  (EXP)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
diarsenic trioxide  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
finasteride  (ISO)
fingolimod hydrochloride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
furan  (ISO)
galangin  (ISO)
gentamycin  (ISO)
glucose  (ISO)
glyphosate  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lycopene  (EXP)
methidathion  (EXP)
nickel atom  (ISO)
oligopeptide  (ISO)
paracetamol  (EXP)
perfluorobutyric acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
platycodin D  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (EXP)
sulindac  (ISO)
syringic acid  (ISO)
T-2 toxin  (EXP,ISO)
theophylline  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
autophagy pathway  (IEA,ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy. Liang B, etal., Int J Mol Med. 2017 Dec;40(6):1781-1791. doi: 10.3892/ijmm.2017.3191. Epub 2017 Oct 16.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. LC3 conjugation system in mammalian autophagy. Tanida I, etal., Int J Biochem Cell Biol. 2004 Dec;36(12):2503-18.
8. The rat Apg3p/Aut1p homolog is upregulated by ischemic preconditioning in the retina. Wu BX, etal., Mol Vis. 2006 Oct 26;12:1292-302.
9. Mammalian autophagy: core molecular machinery and signaling regulation. Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.
10. The protective effect of puerarin-loaded mesoporous silicon nanoparticles on alcoholic hepatitis through mTOR-mediated autophagy pathway. Zhang XX, etal., Biomed Microdevices. 2022 Oct 29;24(4):37. doi: 10.1007/s10544-022-00622-2.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18083104  
PMID:18321988   PMID:18768753   PMID:20144757   PMID:20723759   PMID:21220506   PMID:21421856   PMID:21873635   PMID:22024753   PMID:22055190   PMID:22170151   PMID:22493260   PMID:23184977  
PMID:23202584   PMID:24035364   PMID:24089205   PMID:24191030   PMID:24194600   PMID:24466199   PMID:24591649   PMID:24747438   PMID:24931121   PMID:24954904   PMID:25686249   PMID:26027738  
PMID:26253785   PMID:26440898   PMID:26569626   PMID:26649827   PMID:26764599   PMID:26910393   PMID:27210760   PMID:27303042   PMID:27575019   PMID:27626380   PMID:27852436   PMID:28622295  
PMID:28684613   PMID:28916785   PMID:29150439   PMID:29311554   PMID:30428342   PMID:32325033   PMID:32554809   PMID:32968282   PMID:35449600   PMID:36187486   PMID:36198274   PMID:37224250  
PMID:38212381   PMID:38355793  


Genomics

Comparative Map Data
Atg3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391644,979,192 - 45,008,901 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1644,979,148 - 45,008,901 (+)EnsemblGRCm39 Ensembl
GRCm381645,158,829 - 45,188,538 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1645,158,785 - 45,188,538 (+)EnsemblGRCm38mm10GRCm38
MGSCv371645,158,942 - 45,188,651 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361645,078,161 - 45,107,870 (+)NCBIMGSCv36mm8
Celera1645,552,434 - 45,582,081 (+)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1629.45NCBI
ATG3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383112,532,510 - 112,561,962 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3112,532,510 - 112,562,046 (-)EnsemblGRCh38hg38GRCh38
GRCh373112,251,357 - 112,280,809 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363113,734,049 - 113,763,175 (-)NCBINCBI36Build 36hg18NCBI36
Build 343113,734,049 - 113,763,175NCBI
Celera3110,660,041 - 110,689,158 (-)NCBICelera
Cytogenetic Map3q13.2NCBI
HuRef3109,635,431 - 109,664,875 (-)NCBIHuRef
CHM1_13112,215,286 - 112,244,741 (-)NCBICHM1_1
T2T-CHM13v2.03115,253,546 - 115,282,997 (-)NCBIT2T-CHM13v2.0
Atg3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81169,130,948 - 69,159,280 (-)NCBIGRCr8
mRatBN7.21155,624,914 - 55,653,249 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1155,624,917 - 55,653,224 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,438,596 - 64,466,930 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01157,100,453 - 57,128,787 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01156,170,970 - 56,199,226 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01160,585,192 - 60,613,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1160,585,171 - 60,613,718 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01164,687,322 - 64,715,836 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41157,162,205 - 57,190,568 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11157,219,793 - 57,248,157 (-)NCBI
Celera1155,191,074 - 55,219,238 (-)NCBICelera
Cytogenetic Map11q21NCBI
Atg3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542712,881,454 - 12,906,399 (-)NCBIChiLan1.0ChiLan1.0
ATG3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22110,535,875 - 110,564,655 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13110,539,768 - 110,569,070 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03109,681,163 - 109,710,835 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13116,606,467 - 116,635,209 (-)NCBIpanpan1.1PanPan1.1panPan2
ATG3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13317,046,951 - 17,073,203 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3317,046,973 - 17,073,150 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3317,150,094 - 17,176,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03317,290,643 - 17,316,985 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3317,290,665 - 17,316,925 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13317,095,504 - 17,121,791 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03317,142,968 - 17,169,265 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03317,692,507 - 17,718,820 (-)NCBIUU_Cfam_GSD_1.0
Atg3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602137,263,965 - 137,289,577 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936536232,192 - 257,954 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936536232,343 - 257,949 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13147,279,437 - 147,309,590 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113147,279,110 - 147,309,597 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213156,876,859 - 156,907,063 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATG3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12268,227,772 - 68,256,555 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2268,228,203 - 68,257,503 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604198,205,946 - 98,234,553 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473135,978,595 - 36,004,900 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atg3
1166 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:267
Count of miRNA genes:211
Interacting mature miRNAs:220
Transcripts:ENSMUST00000023343, ENSMUST00000150390
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11059560Lmr12b_mleishmaniasis resistance 12b (mouse)162879281362792952Mouse
1301138Pcd4ts3_mp-glycoprotein positive CD4 T cell subset 3 (mouse)Not determined164059392374594076Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163544664392573008Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2277525257594076Mouse
1301719Remslp3_mrapid eye movement sleep 3 (mouse)Not determined164438335078383506Mouse
1357778Diobq_mdiet-induced obesity QTL (mouse)Not determined164219781782331174Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
11049571Lmr12c_mleishmaniasis resistance 12c (mouse)162879281362792952Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
11059559Lmr12a_mleishmaniasis resistance 12a (mouse)162879281362792952Mouse
4142187Arrd3_mage-related retinal degeneration 3 (mouse)Not determined3252290965466552Mouse
11522747Eae41_mexperimental allergic encephalomyelitis susceptibility 41 (mouse)164039913478015472Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
26884416Bzwq5_mbi-zygomatic width QTL 5, 5 week (mouse)163732036284696888Mouse
1301070Cypr1_mcytokine production 1 (mouse)Not determined163231279566312933Mouse
4142112Skts-fp3_mskin tumor susceptibility in FVB and PWK 3 (mouse)Not determined164005388172924385Mouse
1300915Lmr12_mleishmaniasis resistance 12 (mouse)Not determined162879281362792952Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
4141212Imraq3_mimmune response to AAV2 QTL 3 (mouse)Not determined164438335078383506Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162193838355938574Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
10412263Gvhd6_mgraft-versus host disease 6 (mouse)Not determined163606085745511148Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse

Markers in Region
BB097433  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381645,157,432 - 45,157,546UniSTSGRCm38
MGSCv371645,157,545 - 45,157,659UniSTSGRCm37
Celera1645,550,958 - 45,551,072UniSTS
Cytogenetic Map16B5UniSTS
cM Map1629.9UniSTS
Whitehead/MRC_RH16540.37UniSTS
WI-22015  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381645,187,688 - 45,187,819UniSTSGRCm38
MGSCv371645,187,801 - 45,187,932UniSTSGRCm37
Celera1645,581,230 - 45,581,361UniSTS
Cytogenetic Map16B5UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001356366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_026402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB079386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC129601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK005266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000023343   ⟹   ENSMUSP00000023343
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1644,979,148 - 45,008,901 (+)Ensembl
GRCm38.p6 Ensembl1645,158,785 - 45,188,538 (+)Ensembl
Ensembl Acc Id: ENSMUST00000150390
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1644,986,246 - 45,008,257 (+)Ensembl
GRCm38.p6 Ensembl1645,165,883 - 45,187,894 (+)Ensembl
RefSeq Acc Id: NM_001356366   ⟹   NP_001343295
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391644,979,192 - 45,008,901 (+)NCBI
GRCm381645,158,829 - 45,188,538 (+)NCBI
Sequence:
RefSeq Acc Id: NM_026402   ⟹   NP_080678
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391644,979,192 - 45,008,901 (+)NCBI
GRCm381645,158,829 - 45,188,538 (+)NCBI
MGSCv371645,158,942 - 45,188,651 (+)RGD
Celera1645,552,434 - 45,582,081 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_080678   ⟸   NM_026402
- Peptide Label: isoform 1
- UniProtKB: Q3TXJ9 (UniProtKB/Swiss-Prot),   Q9CPX6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001343295   ⟸   NM_001356366
- Peptide Label: isoform 2
Ensembl Acc Id: ENSMUSP00000023343   ⟸   ENSMUST00000023343

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CPX6-F1-model_v2 AlphaFold Q9CPX6 1-314 view protein structure

Promoters
RGD ID:6827512
Promoter ID:MM_KWN:21099
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000114600,   OTTMUST00000061464,   OTTMUST00000062424
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361645,158,531 - 45,159,497 (-)MPROMDB
RGD ID:8686278
Promoter ID:EPDNEW_M21170
Type:initiation region
Name:Atg3_1
Description:Mus musculus autophagy related 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21171  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381645,158,829 - 45,158,889EPDNEW
RGD ID:8686280
Promoter ID:EPDNEW_M21171
Type:initiation region
Name:Atg3_2
Description:Mus musculus autophagy related 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21170  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381645,159,064 - 45,159,124EPDNEW
RGD ID:6847294
Promoter ID:MM_ACW:20682
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:ATG3.ESEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361645,186,391 - 45,186,891 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915091 AgrOrtholog
Ensembl Genes ENSMUSG00000022663 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023343 ENTREZGENE
  ENSMUST00000023343.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1460.50 UniProtKB/Swiss-Prot
InterPro Atg3 UniProtKB/Swiss-Prot
  Autophagy-rel_prot_3 UniProtKB/Swiss-Prot
KEGG Report mmu:67841 UniProtKB/Swiss-Prot
MGD MGI:1915091 ENTREZGENE
NCBI Gene 67841 ENTREZGENE
PANTHER PTHR12866 UniProtKB/Swiss-Prot
  UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UniProtKB/Swiss-Prot
Pfam Autophagy_act_C UniProtKB/Swiss-Prot
PhenoGen Atg3 PhenoGen
UniProt ATG3_MOUSE UniProtKB/Swiss-Prot
  Q3TXJ9 ENTREZGENE
  Q9CPX6 ENTREZGENE
UniProt Secondary Q3TXJ9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-06-19 Atg3  autophagy related 3  Atg3  autophagy-related 3 (yeast)  Symbol and/or name change 5135510 APPROVED