Atg5 (autophagy related 5) - Rat Genome Database

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Gene: Atg5 (autophagy related 5) Mus musculus
Analyze
Symbol: Atg5
Name: autophagy related 5
RGD ID: 1556965
MGI Page MGI
Description: Predicted to contribute to Atg8-family ligase activity. Involved in several processes, including cellular response to nitrosative stress; macroautophagy; and negative regulation of defense response. Acts upstream of with a positive effect on chromatin organization. Acts upstream of or within several processes, including defense response to symbiont; negative regulation of cardiac muscle cell apoptotic process; and negative stranded viral RNA replication. Located in several cellular components, including autophagosome; mitochondria-associated endoplasmic reticulum membrane contact site; and phagophore assembly site membrane. Part of Atg12-Atg5-Atg16 complex. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in central nervous system; heart; lower jaw molar; and sensory organ. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 25. Orthologous to human ATG5 (autophagy related 5).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 2010107M05Rik; 3110067M24Rik; Ap; APG5-like; Apg5l; Atg5l; autophagy 5-like; autophagy protein 5; autophagy-related 5; autophagy-related 5-like; AW319544; C88337; Pad; Paddy
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391044,144,325 - 44,240,295 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1044,144,354 - 44,240,287 (+)EnsemblGRCm39 Ensembl
GRCm381044,268,322 - 44,364,299 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1044,268,358 - 44,364,291 (+)EnsemblGRCm38mm10GRCm38
MGSCv371043,988,164 - 44,084,097 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361043,956,773 - 44,052,706 (+)NCBIMGSCv36mm8
Celera1045,141,131 - 45,237,099 (+)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1023.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Tetrandrine  (ISO)
(-)-citrinin  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one  (ISO)
2-hydroxyethyl methacrylate  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-hydroxybutyric acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (EXP,ISO)
4'-epidoxorubicin  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
Aescin  (EXP,ISO)
aflatoxin B1  (ISO)
AICA ribonucleotide  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha,alpha-trehalose  (EXP)
alpha-amanitin  (ISO)
alpha-D-galactose  (ISO)
alpha-pinene  (ISO)
Alpinetin  (EXP,ISO)
amiodarone  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
atorvastatin calcium  (EXP)
atrazine  (EXP)
bafilomycin A1  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bortezomib  (EXP)
buprofezin  (ISO)
butachlor  (EXP)
butyric acid  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
camptothecin  (ISO)
candesartan  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon disulfide  (EXP)
carbon nanotube  (EXP,ISO)
carglumic acid  (EXP)
CGP 52608  (ISO)
chloroquine  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
colistin  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
cordycepin  (ISO)
curcumin  (EXP,ISO)
Curcumol  (EXP,ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (EXP,ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
diphenhydramine  (EXP)
disodium selenite  (ISO)
Doramectin  (ISO)
doxorubicin  (EXP,ISO)
ellagic acid  (ISO)
embelin  (ISO)
erastin  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
ferric oxide  (EXP)
ferrostatin-1  (ISO)
fingolimod hydrochloride  (ISO)
flavokawain B  (ISO)
flutamide  (ISO)
folic acid  (EXP)
Fusaric acid  (ISO)
galactose  (ISO)
gefitinib  (ISO)
genistein  (ISO)
geraniol  (ISO)
glucose  (ISO)
glutathione  (EXP)
glycochenodeoxycholic acid  (ISO)
glyphosate  (ISO)
gossypetin  (ISO)
hesperetin  (ISO)
hexadecanoic acid  (ISO)
HU-308  (EXP)
hyaluronic acid  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
JTE-013  (ISO)
kainic acid  (ISO)
L-leucine  (EXP)
lead diacetate  (EXP,ISO)
lead(0)  (EXP,ISO)
levamisole  (EXP)
lipopolysaccharide  (EXP,ISO)
luteolin  (ISO)
LY294002  (EXP)
lycopene  (EXP,ISO)
melatonin  (EXP)
menadione  (EXP,ISO)
methamphetamine  (EXP,ISO)
methoxychlor  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
methylphenidate  (ISO)
microcystin-LR  (EXP)
mitoxantrone  (ISO)
MJN110  (EXP)
N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP)
Nonidet P-40  (ISO)
obeticholic acid  (EXP)
oleanolic acid  (EXP,ISO)
oleic acid  (ISO)
oligopeptide  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
Paeonol  (ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
patulin  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
potassium dichromate  (ISO)
promethazine  (ISO)
propiconazole  (EXP)
pterostilbene  (EXP,ISO)
pyrroloquinoline quinone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
roxadustat  (ISO)
ruthenium red  (ISO)
Sanggenon C  (ISO)
SB 203580  (ISO)
sevoflurane  (ISO)
silicon dioxide  (EXP)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
Soman  (ISO)
sorafenib  (ISO)
sphingosine 1-phosphate  (ISO)
stilbenoid  (ISO)
streptozocin  (EXP,ISO)
swainsonine  (EXP,ISO)
T-2 toxin  (EXP,ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thiacloprid  (EXP)
thymoquinone  (ISO)
trans-piceid  (ISO)
trifluoperazine  (ISO)
Triptolide  (EXP)
trovafloxacin  (ISO)
tunicamycin  (EXP,ISO)
tyloxapol  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)
zearalenone  (EXP)
zinc atom  (ISO)
zinc oxide  (EXP,ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aggrephagy  (IMP,ISO)
antigen processing and presentation of endogenous antigen  (IGI,IMP)
apoptotic process  (IMP)
autophagosome assembly  (IMP,ISO)
autophagy  (IMP,ISO)
autophagy of mitochondrion  (IBA)
axonal transport  (IDA,IEP,IMP)
blood vessel remodeling  (IMP)
cardiac muscle cell apoptotic process  (IMP)
cellular response to nitrogen starvation  (IBA)
cellular response to nitrosative stress  (IMP)
cellular response to starvation  (IMP)
chaperone-mediated autophagy  (ISO)
chromatin organization  (IMP)
defense response to virus  (IMP)
establishment of localization in cell  (IMP)
heart contraction  (IMP)
immune system process  (IEA)
innate immune response  (IMP)
macroautophagy  (IMP,ISO)
mitophagy  (IMP)
mucus secretion  (IMP)
negative regulation of apoptotic process  (IMP,ISO)
negative regulation of autophagic cell death  (ISO)
negative regulation of cardiac muscle cell apoptotic process  (IMP)
negative regulation of defense response to virus  (IDA,ISO)
negative regulation of innate immune response  (IDA)
negative regulation of phagocytosis  (IMP)
negative regulation of protein ubiquitination  (IMP)
negative regulation of reactive oxygen species metabolic process  (IMP)
negative regulation of type I interferon production  (IDA)
negative stranded viral RNA replication  (IMP)
negative thymic T cell selection  (IGI,IMP)
otolith development  (IMP)
piecemeal microautophagy of the nucleus  (IBA)
positive regulation of autophagy  (ISO)
positive regulation of mucus secretion  (IMP)
positive regulation of stress granule assembly  (ISO)
positive regulation of viral translation  (ISO)
post-translational protein modification  (IDA)
postsynaptic modulation of chemical synaptic transmission  (IDA,IMP)
protein lipidation involved in autophagosome assembly  (IBA,IMP)
protein ubiquitination  (IMP)
regulation of autophagosome maturation  (ISO)
regulation of cilium assembly  (IMP)
regulation of cytokine production involved in immune response  (IMP)
regulation of postsynaptic membrane neurotransmitter receptor levels  (IDA,IMP)
regulation of reactive oxygen species metabolic process  (IMP)
regulation of release of sequestered calcium ion into cytosol  (IMP)
response to fluoride  (ISO)
response to fungus  (IMP)
response to iron(II) ion  (ISO)
response to xenobiotic stimulus  (IMP)
vasodilation  (IMP)
ventricular cardiac muscle cell development  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal acrosome assembly  (IAGP)
abnormal adenohypophysis morphology  (IAGP)
abnormal adrenal gland morphology  (IAGP)
abnormal amino acid level  (IAGP)
abnormal autophagosome formation  (IAGP)
abnormal autophagy  (IAGP)
abnormal axon morphology  (IAGP)
abnormal behavior  (IAGP)
abnormal brain morphology  (IAGP)
abnormal cardiac muscle contractility  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal cauda epididymis morphology  (IAGP)
abnormal cell physiology  (IAGP)
abnormal cerebellar granule cell morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal circulating amino acid level  (IAGP)
abnormal circulating chemokine level  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal inferior colliculus morphology  (IAGP)
abnormal intestinal goblet cell morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal lens fiber morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal lysosome morphology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal Paneth cell morphology  (IAGP)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal sperm end piece morphology  (IAGP)
abnormal sperm flagellum morphology  (IAGP)
abnormal sperm head morphology  (IAGP)
abnormal sperm individualization  (IAGP)
abnormal sperm midpiece morphology  (IAGP)
abnormal sperm mitochondrial sheath morphology  (IAGP)
abnormal sperm nucleus morphology  (IAGP)
abnormal spermiation  (IAGP)
abnormal spermiogenesis  (IAGP)
abnormal ST segment  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal T cell morphology  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal T cell subpopulation ratio  (IAGP)
abnormal testis physiology  (IAGP)
abnormal thalamus morphology  (IAGP)
abnormal thymus cortex morphology  (IAGP)
abnormal thymus morphology  (IAGP)
abnormal thymus physiology  (IAGP)
abnormal tumor morphology  (IAGP)
abnormal utricle morphology  (IAGP)
absent gastric milk in neonates  (IAGP)
absent otoliths  (IAGP)
absent sperm fibrous sheath  (IAGP)
alaninuria  (IAGP)
aminoaciduria  (IAGP)
asthenozoospermia  (IAGP)
ataxia  (IAGP)
cataract  (IAGP)
congestive heart failure  (IAGP)
decreased a-wave amplitude  (IAGP)
decreased b-wave amplitude  (IAGP)
decreased body weight  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased cerebral cortex pyramidal cell number  (IAGP)
decreased circulating interleukin-10 level  (IAGP)
decreased grip strength  (IAGP)
decreased T cell number  (IAGP)
decreased T cell proliferation  (IAGP)
decreased testis weight  (IAGP)
decreased tumor growth/size  (IAGP)
dilated heart left ventricle  (IAGP)
double-headed sperm  (IAGP)
enlarged otoliths  (IAGP)
globozoospermia  (IAGP)
glomerulonephritis  (IAGP)
hyperthreoninuria  (IAGP)
immotile sperm  (IAGP)
impaired autophagy  (IAGP)
impaired coordination  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased anti-nuclear antigen antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased circulating creatinine level  (IAGP)
increased circulating interleukin-1 beta level  (IAGP)
increased circulating interleukin-12b level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased heart weight  (IAGP)
increased IgG level  (IAGP)
increased kidney weight  (IAGP)
increased lung weight  (IAGP)
increased lymphocyte cell number  (IAGP)
increased mitochondrial size  (IAGP)
increased monocyte cell number  (IAGP)
increased myocardial fiber size  (IAGP)
increased neutrophil cell number  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased susceptibility to systemic lupus erythematosus  (IAGP)
increased urine glucose level  (IAGP)
increased urine protein level  (IAGP)
limb grasping  (IAGP)
male infertility  (IAGP)
multinucleated giant male germ cells  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neuron degeneration  (IAGP)
neuronal intranuclear inclusions  (IAGP)
no abnormal phenotype detected  (IAGP)
oligozoospermia  (IAGP)
oxidative stress  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
prolonged QT interval  (IAGP)
Purkinje cell degeneration  (IAGP)
reduced male fertility  (IAGP)
short sperm flagellum  (IAGP)
short stride length  (IAGP)
teratozoospermia  (IAGP)
tremors  (IAGP)
tryptophanuria  (IAGP)
valinuria  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons. Castillo K, etal., Autophagy. 2013 Sep;9(9):1308-20. doi: 10.4161/auto.25188. Epub 2013 Jun 6.
2. Physical and transcriptional map of the mouse Chromosome 10 proximal region syntenic to human 6q16-q21. Chalhoub N, etal., Mamm Genome 2001 Dec;12(12):887-92.
3. Cold ischemia-induced autophagy in rat lung tissue. Chen X, etal., Mol Med Rep. 2015 Apr;11(4):2513-9. doi: 10.3892/mmr.2014.2999. Epub 2014 Nov 26.
4. Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast. Hammond EM, etal., FEBS Lett 1998 Apr 3;425(3):391-5.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
7. Changes in autophagy after traumatic brain injury. Liu CL, etal., J Cereb Blood Flow Metab. 2008 Apr;28(4):674-83. Epub 2007 Dec 5.
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. MGD IEA MGD IEA
10. Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method. Mizushima N, etal., FEBS Lett 2002 Dec 18;532(3):450-4.
11. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. Mizushima N, etal., J Cell Biol 2001 Feb 19;152(4):657-68.
12. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. Gene trap insertion into a novel gene expressed during mouse limb development. Pires-DaSilva A and Gruss P, Dev Dyn 1998 Jun;212(2):318-25.
15. Mouse MP Annotation Import Pipeline RGD automated import pipeline
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Early and sustained activation of autophagy in degenerating axons after spinal cord injury. Ribas VT, etal., Brain Pathol. 2015 Mar;25(2):157-70. doi: 10.1111/bpa.12170. Epub 2014 Sep 12.
19. Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. Simonsen A, etal., J Cell Sci 2004 Aug 15;117(Pt 18):4239-51. Epub 2004 Aug 3.
20. Aliskiren ameliorates pressure overload-induced heart hypertrophy and fibrosis in mice. Weng LQ, etal., Acta Pharmacol Sin. 2014 Aug;35(8):1005-14. doi: 10.1038/aps.2014.45. Epub 2014 Jul 7.
21. Mammalian autophagy: core molecular machinery and signaling regulation. Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.
Additional References at PubMed
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PMID:15680329   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16300732   PMID:16602821   PMID:16625204   PMID:16794605   PMID:16885219   PMID:17190837   PMID:17272685   PMID:17350577  
PMID:17450150   PMID:17510285   PMID:17700057   PMID:17709747   PMID:17912025   PMID:18054316   PMID:18097414   PMID:18188005   PMID:18196969   PMID:18268032   PMID:18341993   PMID:18443221  
PMID:18448665   PMID:18452703   PMID:18502787   PMID:18551130   PMID:18591426   PMID:18599786   PMID:18701890   PMID:18782848   PMID:18799693   PMID:18849966   PMID:18946037   PMID:18996346  
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PMID:20144757   PMID:20147545   PMID:20159618   PMID:20171125   PMID:20200449   PMID:20206555   PMID:20417604   PMID:20421418   PMID:20453062   PMID:20519119   PMID:20577052   PMID:20600704  
PMID:20723759   PMID:21041446   PMID:21119005   PMID:21220506   PMID:21241894   PMID:21267068   PMID:21368103   PMID:21378313   PMID:21421825   PMID:21493778   PMID:21498569   PMID:21551061  
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PMID:23863932   PMID:23870125   PMID:23878233   PMID:23878245   PMID:23884556   PMID:23907538   PMID:23918802   PMID:23921551   PMID:23939249   PMID:23954160   PMID:23954414   PMID:24035364  
PMID:24056772   PMID:24089205   PMID:24089209   PMID:24121838   PMID:24185898   PMID:24209762   PMID:24211573   PMID:24240988   PMID:24268578   PMID:24275123   PMID:24275661   PMID:24290752  
PMID:24305049   PMID:24310610   PMID:24315994   PMID:24376899   PMID:24418158   PMID:24441423   PMID:24445999   PMID:24466199   PMID:24550300   PMID:24591649   PMID:24661119   PMID:24668739  
PMID:24705551   PMID:24768629   PMID:24802098   PMID:24815875   PMID:24875860   PMID:24895007   PMID:24903000   PMID:24931121   PMID:24954904   PMID:25060788   PMID:25075440   PMID:25109817  
PMID:25179110   PMID:25216585   PMID:25227738   PMID:25305080   PMID:25316028   PMID:25323583   PMID:25341032   PMID:25362489   PMID:25398946   PMID:25406339   PMID:25437438   PMID:25484072  
PMID:25484092   PMID:25497209   PMID:25526090   PMID:25568088   PMID:25571975   PMID:25585051   PMID:25650776   PMID:25683712   PMID:25695667   PMID:25708836   PMID:25788702   PMID:25833396  
PMID:25888640   PMID:25936644   PMID:25959047   PMID:25985393   PMID:26039325   PMID:26040720   PMID:26043155   PMID:26061908   PMID:26077727   PMID:26090585   PMID:26235979   PMID:26320416  
PMID:26344765   PMID:26384385   PMID:26387641   PMID:26404472   PMID:26416964   PMID:26438374   PMID:26440898   PMID:26502054   PMID:26573705   PMID:26586568   PMID:26649827   PMID:26732594  
PMID:26732653   PMID:26732762   PMID:26749442   PMID:26764599   PMID:26764600   PMID:26808230   PMID:26905199   PMID:26909551   PMID:26929451   PMID:26938300   PMID:26965188   PMID:26975471  
PMID:26986194   PMID:26986811   PMID:27010363   PMID:27021405   PMID:27117419   PMID:27182160   PMID:27210760   PMID:27304991   PMID:27310610   PMID:27325701   PMID:27346657   PMID:27383629  
PMID:27407143   PMID:27411589   PMID:27480114   PMID:27513923   PMID:27568548   PMID:27568566   PMID:27594529   PMID:27607576   PMID:27624289   PMID:27634908   PMID:27693508   PMID:27811852  
PMID:27821769   PMID:27841876   PMID:27869116   PMID:27932448   PMID:27932476   PMID:28031336   PMID:28097232   PMID:28141795   PMID:28213613   PMID:28246295   PMID:28282266   PMID:28294316  
PMID:28296542   PMID:28375544   PMID:28387218   PMID:28465655   PMID:28473584   PMID:28474670   PMID:28492547   PMID:28574506   PMID:28589926   PMID:28683289   PMID:28703297   PMID:28722508  
PMID:28729463   PMID:28768191   PMID:28801209   PMID:28813167   PMID:28916263   PMID:28916785   PMID:28973855   PMID:28973896   PMID:29130363   PMID:29133525   PMID:29175031   PMID:29180572  
PMID:29260931   PMID:29297752   PMID:29306553   PMID:29358083   PMID:29358708   PMID:29438013   PMID:29558368   PMID:29565478   PMID:29618492   PMID:29654322   PMID:29717061   PMID:29791858  
PMID:29793971   PMID:29803835   PMID:29920188   PMID:29940785   PMID:29999454   PMID:30006408   PMID:30131424   PMID:30196744   PMID:30209975   PMID:30245008   PMID:30296435   PMID:30297526  
PMID:30429607   PMID:30472709   PMID:30503339   PMID:30581152   PMID:30608919   PMID:30654731   PMID:30818059   PMID:30818124   PMID:30874544   PMID:30894050   PMID:30900506   PMID:30952864  
PMID:30954217   PMID:31006538   PMID:31036822   PMID:31037145   PMID:31040190   PMID:31059511   PMID:31070476   PMID:31095752   PMID:31116580   PMID:31162135   PMID:31162728   PMID:31199920  
PMID:31257024   PMID:31269441   PMID:31314096   PMID:31346084   PMID:31372669   PMID:31434755   PMID:31451060   PMID:31485654   PMID:31580256   PMID:31601814   PMID:31612776   PMID:31703091  
PMID:31719183   PMID:31748541   PMID:31748850   PMID:31754185   PMID:31818196   PMID:31836471   PMID:31865844   PMID:31879337   PMID:31880208   PMID:31959760   PMID:31959973   PMID:31978760  
PMID:31987928   PMID:32003282   PMID:32019420   PMID:32027825   PMID:32059792   PMID:32084360   PMID:32089264   PMID:32108953   PMID:32128508   PMID:32210230   PMID:32251280   PMID:32290105  
PMID:32313051   PMID:32325033   PMID:32462028   PMID:32473093   PMID:32473999   PMID:32484300   PMID:32532981   PMID:32544365   PMID:32579115   PMID:32677505   PMID:32733884   PMID:32738205  
PMID:32811819   PMID:32840757   PMID:32853550   PMID:32876528   PMID:32951306   PMID:32968282   PMID:32985978   PMID:32989250   PMID:33082312   PMID:33106420   PMID:33124745   PMID:33127558  
PMID:33157003   PMID:33271062   PMID:33277367   PMID:33296658   PMID:33436499   PMID:33459133   PMID:33462315   PMID:33510463   PMID:33522362   PMID:33598715   PMID:33613100   PMID:33645631  
PMID:33668422   PMID:33749503   PMID:33752242   PMID:33854069   PMID:33914811   PMID:33915953   PMID:34009100   PMID:34054582   PMID:34078910   PMID:34088666   PMID:34128834   PMID:34138755  
PMID:34168038   PMID:34253689   PMID:34289347   PMID:34363750   PMID:34374750   PMID:34417924   PMID:34426734   PMID:34469488   PMID:34512629   PMID:34524943   PMID:34552122   PMID:34578904  
PMID:34608496   PMID:34811872   PMID:34870542   PMID:34903064   PMID:34936504   PMID:35032835   PMID:35098856   PMID:35115539   PMID:35197629   PMID:35222391   PMID:35301333   PMID:35303437  
PMID:35342347   PMID:35426127   PMID:35449600   PMID:35452693   PMID:35472080   PMID:35537042   PMID:35966597   PMID:35982178   PMID:35997680   PMID:36044857   PMID:36095911   PMID:36103544  
PMID:36187114   PMID:36198274   PMID:36217034   PMID:36217825   PMID:36261002   PMID:36342387   PMID:36357363   PMID:36522583   PMID:36577069   PMID:36640341   PMID:36649084   PMID:36735498  
PMID:36948186   PMID:37054706   PMID:37131209   PMID:37319285   PMID:37443159   PMID:37460898   PMID:37506696   PMID:37516958   PMID:37543947   PMID:37862166   PMID:37876292   PMID:37909764  
PMID:37915255   PMID:38037161   PMID:38218976   PMID:38368631   PMID:38387460   PMID:38426503   PMID:38490977   PMID:38554280   PMID:38594728   PMID:38852158   PMID:38992049  


Genomics

Comparative Map Data
Atg5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391044,144,325 - 44,240,295 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1044,144,354 - 44,240,287 (+)EnsemblGRCm39 Ensembl
GRCm381044,268,322 - 44,364,299 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1044,268,358 - 44,364,291 (+)EnsemblGRCm38mm10GRCm38
MGSCv371043,988,164 - 44,084,097 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361043,956,773 - 44,052,706 (+)NCBIMGSCv36mm8
Celera1045,141,131 - 45,237,099 (+)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1023.24NCBI
ATG5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386106,184,476 - 106,325,760 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6106,045,423 - 106,325,791 (-)EnsemblGRCh38hg38GRCh38
GRCh376106,632,351 - 106,773,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366106,739,045 - 106,880,388 (-)NCBINCBI36Build 36hg18NCBI36
Build 346106,739,044 - 106,880,359NCBI
Celera6107,253,905 - 107,395,251 (-)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6104,079,375 - 104,220,613 (-)NCBIHuRef
CHM1_16106,894,763 - 107,036,172 (-)NCBICHM1_1
T2T-CHM13v2.06107,360,315 - 107,501,922 (-)NCBIT2T-CHM13v2.0
Atg5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82049,380,835 - 49,471,826 (+)NCBIGRCr8
mRatBN7.22047,798,217 - 47,889,216 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2047,798,290 - 47,889,209 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2049,539,098 - 49,629,485 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02049,188,983 - 49,279,371 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02049,872,609 - 49,962,985 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02049,301,783 - 49,393,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2049,318,308 - 49,393,140 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02050,934,688 - 51,026,125 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42048,273,977 - 48,366,743 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12048,302,673 - 48,395,435 (+)NCBI
Celera2052,117,260 - 52,207,732 (-)NCBICelera
Cytogenetic Map20q13NCBI
Atg5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541131,522,420 - 31,646,827 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541131,501,191 - 31,646,407 (-)NCBIChiLan1.0ChiLan1.0
ATG5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25126,183,703 - 126,346,578 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16124,071,501 - 124,233,849 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06103,997,824 - 104,140,931 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16107,871,201 - 108,027,064 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6107,871,208 - 108,013,807 (-)Ensemblpanpan1.1panPan2
ATG5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11263,565,859 - 63,692,383 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1263,567,568 - 63,683,485 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1263,353,188 - 63,480,151 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01264,411,072 - 64,538,081 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1264,410,753 - 64,538,102 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11263,770,621 - 63,897,766 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01263,612,694 - 63,739,640 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01263,886,649 - 64,013,653 (-)NCBIUU_Cfam_GSD_1.0
Atg5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494698,484,245 - 98,610,566 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365642,758,598 - 2,885,420 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365642,759,085 - 2,885,394 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl172,270,799 - 72,520,396 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1172,343,950 - 72,520,402 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ATG5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11367,482,538 - 67,619,201 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1367,482,595 - 67,617,902 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604039,817,584 - 39,954,576 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478015,987,397 - 16,124,151 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478015,987,483 - 16,124,158 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atg5
3372 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:326
Count of miRNA genes:264
Interacting mature miRNAs:285
Transcripts:ENSMUST00000039286
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
21079434Bdym5_mbody mass QTL 5 (mouse)104054599654836096Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
10045632Heal16_mwound healing/regeneration 16 (mouse)Not determined103097449964974630Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
1357558Bmch4_mbone mechanical trait 4 (mouse)Not determined103157713665577284Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
27095920Pglq9_mpelvic girdle length QTL 9, 10 week (mouse)103377599670835830Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
1300898Cfid_mcystic fibrosis intestinal distress (mouse)Not determined102972040363720483Mouse
4141070Ltgq1_mliver triglyceride QTL 1 (mouse)Not determined4123732675237326Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
4142209Psrs1_mpsoriasis susceptibility 1 (mouse)Not determined102689026446720483Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse

Markers in Region
C88337  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381044,364,053 - 44,364,258UniSTSGRCm38
MGSCv371044,083,859 - 44,084,064UniSTSGRCm37
Celera1045,236,861 - 45,237,066UniSTS
Cytogenetic Map10B2UniSTS
cM Map1026.0UniSTS
Whitehead/MRC_RH10502.93UniSTS
AW319544  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381044,362,939 - 44,363,077UniSTSGRCm38
MGSCv371044,082,745 - 44,082,883UniSTSGRCm37
Celera1045,235,747 - 45,235,885UniSTS
Cytogenetic Map10B2UniSTS
cM Map1026.0UniSTS
Whitehead/MRC_RH10509.47UniSTS
Atg5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10B2UniSTS
cM Map1026.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001314013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB048349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC155642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY126779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD776008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX223012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG656078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000039286   ⟹   ENSMUSP00000044769
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1044,144,354 - 44,240,287 (+)Ensembl
GRCm38.p6 Ensembl1044,268,358 - 44,364,291 (+)Ensembl
Ensembl Acc Id: ENSMUST00000217412
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1044,144,411 - 44,170,670 (+)Ensembl
GRCm38.p6 Ensembl1044,268,415 - 44,294,674 (+)Ensembl
RefSeq Acc Id: NM_001314013   ⟹   NP_001300942
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391044,144,335 - 44,240,295 (+)NCBI
GRCm381044,268,339 - 44,364,299 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001358596   ⟹   NP_001345525
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391044,144,335 - 44,240,295 (+)NCBI
GRCm381044,268,339 - 44,364,299 (+)NCBI
Sequence:
RefSeq Acc Id: NM_053069   ⟹   NP_444299
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391044,144,335 - 44,240,295 (+)NCBI
GRCm381044,268,339 - 44,364,299 (+)NCBI
MGSCv371043,988,164 - 44,084,097 (+)RGD
Celera1045,141,131 - 45,237,099 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011243108   ⟹   XP_011241410
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391044,144,328 - 44,239,640 (+)NCBI
GRCm381044,268,331 - 44,363,644 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017313783   ⟹   XP_017169272
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391044,144,325 - 44,195,554 (+)NCBI
GRCm381044,268,322 - 44,319,558 (+)NCBI
Sequence:
RefSeq Acc Id: NP_444299   ⟸   NM_053069
- Peptide Label: isoform 1
- UniProtKB: Q99J83 (UniProtKB/Swiss-Prot),   A0A385JBX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241410   ⟸   XM_011243108
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001300942   ⟸   NM_001314013
- Peptide Label: isoform 2
- UniProtKB: Q99J83 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017169272   ⟸   XM_017313783
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001345525   ⟸   NM_001358596
- Peptide Label: isoform 3
Ensembl Acc Id: ENSMUSP00000044769   ⟸   ENSMUST00000039286
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99J83-F1-model_v2 AlphaFold Q99J83 1-275 view protein structure

Promoters
RGD ID:6819022
Promoter ID:MM_KWN:4057
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_053069
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361043,987,896 - 43,988,396 (+)MPROMDB
RGD ID:8671926
Promoter ID:EPDNEW_M13994
Type:initiation region
Name:Atg5_1
Description:Mus musculus autophagy related 5 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381044,268,400 - 44,268,460EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1277186 AgrOrtholog
Ensembl Genes ENSMUSG00000038160 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000039286 ENTREZGENE
  ENSMUST00000039286.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.246.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.20.620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Atg5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_HBR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg5_HR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_UblA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg5_UblA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_UblB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11793 UniProtKB/Swiss-Prot
MGD MGI:1277186 ENTREZGENE
NCBI Gene 11793 ENTREZGENE
PANTHER AUTOPHAGY PROTEIN 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13040 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam APG5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_HBR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_UblA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atg5 PhenoGen
UniProt A0A385JBX3 ENTREZGENE, UniProtKB/TrEMBL
  ATG5_MOUSE UniProtKB/Swiss-Prot
  Q8CF05_MOUSE UniProtKB/TrEMBL
  Q99J83 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-06-19 Atg5  autophagy related 5  Atg5  autophagy-related 5 (yeast)  Symbol and/or name change 5135510 APPROVED