Nectin1 (nectin cell adhesion molecule 1) - Rat Genome Database

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Gene: Nectin1 (nectin cell adhesion molecule 1) Mus musculus
Analyze
Symbol: Nectin1
Name: nectin cell adhesion molecule 1
RGD ID: 1556913
MGI Page MGI
Description: Enables protein homodimerization activity and signaling receptor activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Acts upstream of or within several processes, including camera-type eye development; desmosome organization; and enamel mineralization. Located in adherens junction; apical junction complex; and cell-cell contact zone. Is active in hippocampal mossy fiber to CA3 synapse and presynaptic active zone membrane. Is expressed in several structures, including brain; oral region epithelium; renal vesicle; sensory organ; and upper jaw molar. Human ortholog(s) of this gene implicated in cleft lip; cleft lip-palate-ectodermal dysplasia syndrome; cleft palate; and ectodermal dysplasia. Orthologous to human NECTIN1 (nectin cell adhesion molecule 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI835281; AW549174; Cd111; herpes virus entry mediator C; herpesvirus entry mediator C; HI; HIgR; Hve; HveC; necti; nectin-1; nectin-1 alpha; nectin-1 delta; P; poliovirus receptor-related 1; poliovirus receptor-related protein 1; PRR; PRR1; Pvrl1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39943,655,251 - 43,718,758 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl943,655,281 - 43,743,955 (+)EnsemblGRCm39 Ensembl
GRCm38943,737,075 - 43,807,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl943,743,984 - 43,832,658 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl943,743,984 - 43,807,461 (+)EnsemblGRCm38mm10GRCm38
MGSCv37943,552,659 - 43,615,544 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36943,495,571 - 43,558,456 (+)NCBIMGSCv36mm8
Celera941,000,673 - 41,063,599 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
cM Map924.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-4,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
alendronic acid  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
buta-1,3-diene  (EXP)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
capsaicin  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
chrysene  (EXP)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (ISO)
diquat  (EXP)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
flavonoids  (ISO)
folic acid  (EXP)
fonofos  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
iron dichloride  (ISO)
leflunomide  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
methylarsonic acid  (EXP)
N(4)-hydroxycytidine  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-Nitrosopyrrolidine  (ISO)
ochratoxin A  (ISO)
paracetamol  (ISO)
parathion  (ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
tamoxifen  (EXP)
terbufos  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (ISO)
tetraphene  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Role of Nectin-1/c-Src Signaling in the Analgesic Effect of GDNF on a Rat Model of Chronic Constrictive Injury. Gao YY, etal., J Mol Neurosci. 2016 Oct;60(2):258-66. doi: 10.1007/s12031-016-0792-x. Epub 2016 Jul 9.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia. Suzuki K, etal., Nat Genet. 2000 Aug;25(4):427-30.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10744716   PMID:10781093   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11090177   PMID:11217851   PMID:11289808   PMID:11827984   PMID:12376527  
PMID:12477932   PMID:12515806   PMID:12584355   PMID:12788073   PMID:12826663   PMID:12904583   PMID:14610273   PMID:14963155   PMID:15108322   PMID:15328010   PMID:15361870   PMID:15485841  
PMID:15550395   PMID:15728677   PMID:16141072   PMID:16141073   PMID:16300961   PMID:16524929   PMID:16602821   PMID:16679515   PMID:16801389   PMID:16823958   PMID:16877297   PMID:17145500  
PMID:17472964   PMID:17967808   PMID:17971293   PMID:18005714   PMID:18181141   PMID:18204934   PMID:18431835   PMID:18703497   PMID:18799693   PMID:19116242   PMID:19255144   PMID:19805039  
PMID:21038445   PMID:21267068   PMID:21769484   PMID:21795335   PMID:21798896   PMID:21873635   PMID:21910732   PMID:21945075   PMID:22118475   PMID:22321830   PMID:22512338   PMID:23097453  
PMID:23184983   PMID:23213272   PMID:23487309   PMID:23533177   PMID:23539219   PMID:23658188   PMID:23931996   PMID:24236178   PMID:24381198   PMID:24952961   PMID:25320325   PMID:25387952  
PMID:25826454   PMID:25859222   PMID:25967681   PMID:25988834   PMID:26136572   PMID:26169026   PMID:26212757   PMID:26663531   PMID:26757815   PMID:26802325   PMID:26929452   PMID:27486990  
PMID:28604778   PMID:28752362   PMID:29444423   PMID:30529655   PMID:30814219   PMID:32275969   PMID:32325033   PMID:32554531   PMID:32554809   PMID:33160402   PMID:33416101   PMID:35379771  
PMID:36417873   PMID:38030279   PMID:38187761  


Genomics

Comparative Map Data
Nectin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39943,655,251 - 43,718,758 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl943,655,281 - 43,743,955 (+)EnsemblGRCm39 Ensembl
GRCm38943,737,075 - 43,807,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl943,743,984 - 43,832,658 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl943,743,984 - 43,807,461 (+)EnsemblGRCm38mm10GRCm38
MGSCv37943,552,659 - 43,615,544 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36943,495,571 - 43,558,456 (+)NCBIMGSCv36mm8
Celera941,000,673 - 41,063,599 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
cM Map924.42NCBI
NECTIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,638,098 - 119,729,200 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,623,408 - 119,729,200 (-)EnsemblGRCh38hg38GRCh38
GRCh3711119,508,808 - 119,599,910 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611119,014,018 - 119,104,645 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411119,050,309 - 119,104,645NCBI
Celera11116,669,897 - 116,760,980 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11115,451,054 - 115,541,412 (-)NCBIHuRef
CHM1_111119,396,685 - 119,487,290 (-)NCBICHM1_1
T2T-CHM13v2.011119,660,108 - 119,752,026 (-)NCBIT2T-CHM13v2.0
Nectin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8852,998,662 - 53,061,745 (+)NCBIGRCr8
mRatBN7.2844,101,776 - 44,164,863 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,101,776 - 44,189,787 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx849,600,140 - 49,663,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0847,878,811 - 47,941,870 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0845,746,411 - 45,809,474 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,094,233 - 48,198,499 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,094,673 - 48,157,305 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0846,714,981 - 46,777,484 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4846,739,657 - 46,799,051 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1846,807,104 - 46,807,754 (+)NCBI
Celera843,690,971 - 43,754,034 (+)NCBICelera
Cytogenetic Map8q22NCBI
Nectin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,682,861 - 20,745,069 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,683,007 - 20,745,069 (-)NCBIChiLan1.0ChiLan1.0
NECTIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29120,339,862 - 120,432,463 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111121,443,077 - 121,535,702 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011114,497,177 - 114,565,338 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111118,425,181 - 118,493,090 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11118,401,321 - 118,493,090 (-)Ensemblpanpan1.1panPan2
NECTIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,228,197 - 14,292,825 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,228,197 - 14,315,060 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,282,464 - 14,346,907 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,172,083 - 14,236,744 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,170,280 - 14,258,980 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,310,592 - 14,375,074 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,214,689 - 14,278,846 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,254,410 - 14,319,094 (+)NCBIUU_Cfam_GSD_1.0
Nectin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,579,611 - 101,680,935 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365424,539,931 - 4,602,344 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365424,501,081 - 4,602,338 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NECTIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,789,726 - 46,891,304 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,823,552 - 46,891,564 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,881,267 - 51,894,114 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NECTIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11111,046,310 - 111,116,906 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1111,046,333 - 111,116,698 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604314,924,098 - 14,989,691 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nectin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,997,424 - 15,059,761 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,997,533 - 15,058,971 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nectin1
2238 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1861
Count of miRNA genes:679
Interacting mature miRNAs:871
Transcripts:ENSMUST00000034510
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9991076843910768Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
1301007Pid2_mprion incubation determinant 2 (mouse)Not determined93715336244251323Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
12738415Lfibq8_mliver fibrosis QTL 8 (mouse)94140216245343743Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
13432191Actrse4_mactivity response to saline/ethanol 4 (mouse)94370321448603195Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
10045613Rapop7_mradiation-induced apoptosis 6 (mouse)Not determined93673624349420511Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
11532693Sluc39_msusceptibility to lung cancer 39 (mouse)94064537448351476Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
1558993Tdmq1_mtype 2 diabetes modifying QTL 1 (mouse)Not determined94041959451808670Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
13515055Adip20a_madiposity 20a (mouse)94269071644053852Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
1301501Lmr2_mleishmaniasis resistance 2 (mouse)Not determined93694340650111140Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse

Markers in Region
AW549174  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38943,806,898 - 43,806,990UniSTSGRCm38
MGSCv37943,614,981 - 43,615,073UniSTSGRCm37
Celera941,063,036 - 41,063,128UniSTS
Cytogenetic Map9BUniSTS
Whitehead/MRC_RH9488.6UniSTS
Pvrl1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9BUniSTS
cM Map9 UniSTS
AI835281  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38943,806,619 - 43,806,731UniSTSGRCm38
MGSCv37943,614,702 - 43,614,814UniSTSGRCm37
Celera941,062,757 - 41,062,869UniSTS
Cytogenetic Map9BUniSTS
Whitehead/MRC_RH9488.58UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000034510   ⟹   ENSMUSP00000034510
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl943,655,281 - 43,718,758 (+)Ensembl
GRCm38.p6 Ensembl943,743,984 - 43,807,461 (+)Ensembl
Ensembl Acc Id: ENSMUST00000180221
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl943,741,128 - 43,743,955 (+)Ensembl
GRCm38.p6 Ensembl943,829,831 - 43,832,658 (+)Ensembl
Ensembl Acc Id: ENSMUST00000216893   ⟹   ENSMUSP00000149131
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl943,705,418 - 43,717,172 (+)Ensembl
GRCm38.p6 Ensembl943,794,121 - 43,805,875 (+)Ensembl
Ensembl Acc Id: ENSMUST00000216905
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl943,732,244 - 43,742,697 (+)Ensembl
GRCm38.p6 Ensembl943,820,947 - 43,831,400 (+)Ensembl
Ensembl Acc Id: ENSMUST00000239313   ⟹   ENSMUSP00000159280
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl943,655,941 - 43,743,819 (+)Ensembl
GRCm38.p6 Ensembl943,744,644 - 43,832,522 (+)Ensembl
RefSeq Acc Id: NM_021424   ⟹   NP_067399
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39943,655,251 - 43,718,758 (+)NCBI
GRCm38943,743,954 - 43,807,461 (+)NCBI
MGSCv37943,552,659 - 43,615,544 (+)RGD
Celera941,000,673 - 41,063,599 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_067399   ⟸   NM_021424
- Peptide Label: precursor
- UniProtKB: Q9ERL5 (UniProtKB/Swiss-Prot),   Q6P9M9 (UniProtKB/Swiss-Prot),   Q9JI17 (UniProtKB/Swiss-Prot),   Q9JKF6 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000149131   ⟸   ENSMUST00000216893
Ensembl Acc Id: ENSMUSP00000034510   ⟸   ENSMUST00000034510
Ensembl Acc Id: ENSMUSP00000159280   ⟸   ENSMUST00000239313
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JKF6-F1-model_v2 AlphaFold Q9JKF6 1-515 view protein structure

Promoters
RGD ID:6845001
Promoter ID:MM_KWN:57067
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000034510
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36943,551,181 - 43,552,212 (+)MPROMDB
RGD ID:8669340
Promoter ID:EPDNEW_M12700
Type:initiation region
Name:Nectin1_1
Description:Mus musculus nectin cell adhesion molecule 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38943,744,634 - 43,744,694EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1926483 AgrOrtholog
Ensembl Genes ENSMUSG00000032012 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000034510 ENTREZGENE
  ENSMUST00000034510.9 UniProtKB/Swiss-Prot
  ENSMUST00000216893.2 UniProtKB/TrEMBL
  ENSMUST00000239313.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nectin-1_Ig1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nectin-1_Ig2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nectin/Nectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:58235 UniProtKB/Swiss-Prot
MGD MGI:1926483 ENTREZGENE
NCBI Gene 58235 ENTREZGENE
PANTHER NECTIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23277:SF69 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nectin1 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1SQP1_MOUSE UniProtKB/TrEMBL
  A0A668KLC0_MOUSE UniProtKB/TrEMBL
  NECT1_MOUSE UniProtKB/Swiss-Prot
  Q6P9M9 ENTREZGENE
  Q9ERL5 ENTREZGENE
  Q9JI17 ENTREZGENE
  Q9JKF6 ENTREZGENE
UniProt Secondary Q6P9M9 UniProtKB/Swiss-Prot
  Q9ERL5 UniProtKB/Swiss-Prot
  Q9JI17 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-26 Nectin1  nectin cell adhesion molecule 1  Pvrl1  poliovirus receptor-related 1  Symbol and/or name change 5135510 APPROVED