Pde3a<sup>em3Bdr</sup> (phosphodiesterase 3A; Cas9/Cas9 induced mutant 3, Bdr) - Rat Genome Database

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Gene: Pde3aem3Bdr (phosphodiesterase 3A; Cas9/Cas9 induced mutant 3, Bdr) Rattus norvegicus
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Symbol: Pde3aem3Bdr
Name: phosphodiesterase 3A; Cas9/Cas9 induced mutant 3, Bdr
RGD ID: 155631299
Description: The rat mutant allele was generated by pronuclear microinjection of Sprague-Dawley rat zygotes with a mixture of Cas9/Cas9 system to target the catalytic domain in the rat Pde3a gene. The model has a carriesa CGT to TGT missense mutation and results in R862C substitutions in the protein
Type: allele  of Pde3a  
Previously known as: Pde3a^[em3Bdr]
Is Marker For: Strains:   SD-Pde3aem3Bdr  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage. Ercu M, etal., Circulation. 2022 Oct 19:101161CIRCULATIONAHA122060210. doi: 10.1161/CIRCULATIONAHA.122.060210.

Genomics


Related Rat Strains
The following Strains have been annotated to Pde3aem3Bdr
SD-Pde3aem3Bdr    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information