Ctns<sup>em2Vjupk</sup> (cystinosin, lysosomal cystine transporter; CRISPR/Cas9 induced mutant 2, Vjupk) - Rat Genome Database

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Gene: Ctnsem2Vjupk (cystinosin, lysosomal cystine transporter; CRISPR/Cas9 induced mutant 2, Vjupk) Rattus norvegicus
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Symbol: Ctnsem2Vjupk
Name: cystinosin, lysosomal cystine transporter; CRISPR/Cas9 induced mutant 2, Vjupk
RGD ID: 155630632
Description: This 2-bp insertion in the Crl:CD(SD) embryo was induced by CRISPR/Cas9 system targeting exon3 of the rat Ctns gene. The insertion causes frameshift mutation and results in pre-mature stop truncated protein.
Type: allele  of Ctns  
Previously known as: Ctns^[em2Vjupk]; CtnsE3N-2Vjupk/Vju
Is Marker For: Strains:   CD-Ctnsem2Vjupk  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Cystinosin-deficient rats recapitulate the phenotype of nephropathic cystinosis. Hollywood JA, etal., Am J Physiol Renal Physiol. 2022 Aug 1;323(2):F156-F170. doi: 10.1152/ajprenal.00277.2021. Epub 2022 Jun 13.

Genomics


Related Rat Strains
The following Strains have been annotated to Ctnsem2Vjupk
CD-Ctnsem2Vjupk    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information