Bmal1<sup>em1Mcwi</sup> (basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi) - Rat Genome Database

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Gene: Bmal1em1Mcwi (basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi) Rattus norvegicus
Symbol: Bmal1em1Mcwi
Name: basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi
RGD ID: 155598603
Description: CRISPR/Cas9 system was used to introduce a 58-base pair deletion in exon 6 in the rat Bmal1 gene of Crl:SD embryos. The deletion caused a premature stop codon in exon 6 resulting in a severe truncation of the Bmal1 protein.
ASSOCIATED WITH abnormal urine sodium level; decreased body weight; decreased food intake
Type: allele  of Bmal1  
Previously known as: Bmal1^[em1Mcwi]
Is Marker For: Strains:   SD-Bmal1em1Mcwi  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References - curated
# Reference Title Reference Citation
1. Diurnal Control of Blood Pressure Is Uncoupled From Sodium Excretion. Johnston JG, etal., Hypertension. 2020 Jun;75(6):1624-1634. doi: 10.1161/HYPERTENSIONAHA.119.13908. Epub 2020 Apr 20.


Related Rat Strains
The following Strains have been annotated to Bmal1em1Mcwi



Nucleotide Sequences

Additional Information