Id3 (inhibitor of DNA binding 3) - Rat Genome Database

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Gene: Id3 (inhibitor of DNA binding 3) Mus musculus
Analyze
Symbol: Id3
Name: inhibitor of DNA binding 3
RGD ID: 1553777
MGI Page MGI
Description: Enables several functions, including bHLH transcription factor binding activity; leptomycin B binding activity; and transcription regulator inhibitor activity. Involved in several processes, including negative regulation of myoblast differentiation; notochord development; and regulation of gene expression. Acts upstream of or within several processes, including cellular response to leptomycin B; negative regulation of macromolecule biosynthetic process; and negative regulation of osteoblast differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; limb; metanephros; and sensory organ. Used to study Sjogren's syndrome. Orthologous to human ID3 (inhibitor of DNA binding 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bHLHb2; bHLHb25; DNA-binding protein inhibitor ID-3; HLH46; Hlh462; ID-like protein inhibitor HLH 462; Idb; Idb3; inhibitor of differentiation 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394135,871,133 - 135,872,703 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4135,870,808 - 135,873,066 (+)EnsemblGRCm39 Ensembl
GRCm384136,143,822 - 136,145,392 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4136,143,497 - 136,145,755 (+)EnsemblGRCm38mm10GRCm38
MGSCv374135,699,737 - 135,701,307 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364135,415,898 - 135,417,463 (+)NCBIMGSCv36mm8
Celera4134,340,192 - 134,341,762 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map468.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(R)-pantothenic acid  (ISO)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,4-dichloroaniline  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
Actein  (ISO)
adenine  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
arachidonic acid  (ISO)
Archazolid B  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (EXP,ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butyric acid  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (EXP)
caffeine  (ISO)
calciol  (EXP)
calyculin a  (EXP)
carbon nanotube  (EXP,ISO)
carnosic acid  (EXP)
CGP 52608  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clobetasol  (EXP)
clofibrate  (EXP)
clomiphene  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
Cyclopamine  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
DDE  (ISO)
dexamethasone  (EXP,ISO)
diallyl disulfide  (ISO)
Dibutyl phosphate  (ISO)
dichloromethane  (EXP)
diclofenac  (EXP)
diethyl maleate  (EXP)
diethylstilbestrol  (ISO)
dimethoate  (ISO)
diquat  (EXP)
diuron  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
estrone  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
ferric oxide  (EXP)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (ISO)
furosemide  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
glucose  (EXP)
glycidol  (ISO)
glyphosate  (EXP)
hexadecanoic acid  (EXP)
hexestrol  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indole-3-methanol  (ISO)
iodoacetic acid  (ISO)
Iopanoic acid  (ISO)
iron dichloride  (ISO)
lead diacetate  (EXP)
leflunomide  (ISO)
leptomycin B  (EXP)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
mestranol  (ISO)
methamphetamine  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methoxyacetic acid  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
Monobutylphthalate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP)
ochratoxin A  (ISO)
orphenadrine  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paricalcitol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phenol  (ISO)
phenylarsine oxide  (EXP)
PhIP  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
pinostrobin  (ISO)
pirinixic acid  (EXP,ISO)
prednisolone  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
prostaglandin F2alpha  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
resorcinol  (ISO)
resveratrol  (ISO)
retinyl acetate  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
Securinine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
succimer  (EXP,ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (EXP)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
triacsin C  (ISO)
tributylstannane  (EXP)
trichloroethene  (ISO)
triclosan  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA)
nucleus  (IBA,IMP)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal brain morphology  (IAGP)
abnormal brain vasculature morphology  (IAGP)
abnormal cell cycle  (IAGP)
abnormal cortical ventricular zone morphology  (IAGP)
abnormal double-positive T cell morphology  (IAGP)
abnormal embryonic/fetal subventricular zone morphology  (IAGP)
abnormal eye morphology  (IAGP)
abnormal kidney morphology  (IEA)
abnormal lacrimal gland morphology  (IAGP)
abnormal liver morphology  (IEA)
abnormal middle ear morphology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal retina blood vessel morphology  (IEA)
abnormal retina development  (IAGP)
abnormal spleen morphology  (IEA)
abnormal T cell differentiation  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal testis morphology  (IEA)
abnormal tumor vascularization  (IAGP)
conductive hearing loss  (IAGP)
cornea opacity  (IEA)
decreased angiogenesis  (IAGP)
decreased B cell proliferation  (IAGP)
decreased body length  (IEA)
decreased brain size  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased distortion product otoacoustic emission amplitude  (IAGP)
decreased embryo weight  (IAGP)
decreased immunoglobulin level  (IAGP)
decreased metastatic potential  (IAGP)
decreased prepulse inhibition  (IEA)
decreased salivation  (IAGP)
decreased T cell number  (IAGP)
decreased tear production  (IAGP)
decreased thymocyte number  (IAGP)
decreased tumor growth/size  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged brain ventricles  (IAGP)
enlarged spleen  (IEA)
increased autoantibody level  (IAGP)
increased B cell number  (IAGP)
increased CD4-positive, alpha-beta memory T cell number  (IAGP)
increased CD8-positive, alpha-beta memory T cell number  (IAGP)
increased freezing behavior  (IEA)
increased gamma-delta T cell number  (IAGP)
increased mean corpuscular volume  (IEA)
increased mean platelet volume  (IEA)
increased or absent threshold for auditory brainstem response  (IAGP)
increased red blood cell distribution width  (IEA)
increased spleen weight  (IEA)
increased startle reflex  (IEA)
increased susceptibility to otitis media  (IAGP)
increased T follicular helper cell number  (IAGP)
intracranial hemorrhage  (IAGP)
lacrimal gland inflammation  (IAGP)
microphthalmia  (IAGP)
middle ear effusion  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IEA)
parotid gland inflammation  (IAGP)
premature cranial suture closure  (IAGP)
premature neuronal precursor differentiation  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
retina hypoplasia  (IAGP)
salivary gland inflammation  (IAGP)
small kidney  (IEA)
small lens  (IAGP)
small liver  (IEA)
small testis  (IEA)
submandibular gland inflammation  (IAGP)
thin external granule cell layer  (IAGP)
tumor regression  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Upregulation of the HLH Id gene family in neural progenitors and glial cells of the rat spinal cord following contusion injury. Tzeng SF, etal., J Neurosci Res. 2001 Dec 15;66(6):1161-72.
Additional References at PubMed
PMID:1628620   PMID:2000388   PMID:7547505   PMID:7655079   PMID:7671812   PMID:8083744   PMID:8139914   PMID:8197168   PMID:8679000   PMID:8759016   PMID:8853903   PMID:8889548  
PMID:8922523   PMID:8989524   PMID:8999959   PMID:9030551   PMID:9372963   PMID:9418957   PMID:10197587   PMID:10349636   PMID:10391928   PMID:10454544   PMID:10534616   PMID:10537105  
PMID:10661402   PMID:10837126   PMID:10862700   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11731246   PMID:11840326   PMID:12118260   PMID:12167713   PMID:12477932   PMID:12532109  
PMID:12702772   PMID:12805214   PMID:12819125   PMID:12858547   PMID:14526102   PMID:14585355   PMID:14610273   PMID:15016815   PMID:15078898   PMID:15084498   PMID:15161906   PMID:15184986  
PMID:15226823   PMID:15294959   PMID:15321928   PMID:15342397   PMID:15368360   PMID:15451666   PMID:15469980   PMID:15472070   PMID:15485632   PMID:15530557   PMID:15618518   PMID:15782199  
PMID:15800025   PMID:15858069   PMID:15858404   PMID:15894277   PMID:16037566   PMID:16079153   PMID:16141072   PMID:16141073   PMID:16177095   PMID:16200063   PMID:16216350   PMID:16322470  
PMID:16407553   PMID:16502419   PMID:16556596   PMID:16602821   PMID:16682435   PMID:16869774   PMID:16887829   PMID:16990548   PMID:17158062   PMID:17359964   PMID:17472721   PMID:17535249  
PMID:17573777   PMID:17604724   PMID:17622570   PMID:17644613   PMID:17681138   PMID:17823941   PMID:17878368   PMID:18069898   PMID:18287524   PMID:18287559   PMID:18477564   PMID:18498827  
PMID:18519801   PMID:18557763   PMID:18669923   PMID:18692041   PMID:18772115   PMID:18823948   PMID:19096764   PMID:19121383   PMID:19122139   PMID:19191219   PMID:19217292   PMID:19349107  
PMID:19380777   PMID:19458195   PMID:19521566   PMID:19605688   PMID:19741146   PMID:19757990   PMID:19833086   PMID:20019328   PMID:20020054   PMID:20038637   PMID:20059953   PMID:20130285  
PMID:20174563   PMID:20181926   PMID:20185798   PMID:20211142   PMID:20392740   PMID:20412781   PMID:20445055   PMID:20463050   PMID:20534673   PMID:20551904   PMID:20554876   PMID:20600660  
PMID:20674402   PMID:20852128   PMID:20932862   PMID:20937270   PMID:20947825   PMID:21030215   PMID:21056086   PMID:21131965   PMID:21145943   PMID:21148110   PMID:21172336   PMID:21267068  
PMID:21354309   PMID:21565611   PMID:21597012   PMID:21731673   PMID:21801865   PMID:21852201   PMID:21857655   PMID:21862448   PMID:21873635   PMID:21924496   PMID:21940780   PMID:21953618  
PMID:21964314   PMID:22016354   PMID:22034493   PMID:22057288   PMID:22057289   PMID:22075252   PMID:22130515   PMID:22234186   PMID:22326917   PMID:22354994   PMID:22425249   PMID:22465667  
PMID:22522171   PMID:22585759   PMID:22711520   PMID:22923088   PMID:22972921   PMID:22984456   PMID:22988430   PMID:23042815   PMID:23193000   PMID:23241957   PMID:23355737   PMID:23477786  
PMID:23523789   PMID:23824195   PMID:23904442   PMID:23968833   PMID:24115031   PMID:24123680   PMID:24146773   PMID:24204301   PMID:24238961   PMID:24244015   PMID:24336726   PMID:24379125  
PMID:24442143   PMID:24463518   PMID:24470501   PMID:24516656   PMID:24583261   PMID:24706811   PMID:24854879   PMID:24859004   PMID:24952961   PMID:24973820   PMID:25010390   PMID:25051963  
PMID:25151262   PMID:25209090   PMID:25636209   PMID:25691468   PMID:25737280   PMID:25810530   PMID:25951516   PMID:25951976   PMID:26082558   PMID:26135667   PMID:26232435   PMID:26238476  
PMID:26322481   PMID:26382297   PMID:26438726   PMID:26859080   PMID:26868208   PMID:27128622   PMID:27213691   PMID:27217539   PMID:27457619   PMID:27487330   PMID:27492475   PMID:27506655  
PMID:27654891   PMID:27889898   PMID:27974197   PMID:27986952   PMID:28077488   PMID:28172500   PMID:28258199   PMID:28844693   PMID:28990057   PMID:29282254   PMID:29285798   PMID:29540665  
PMID:29771958   PMID:30012846   PMID:30201295   PMID:30352686   PMID:30518568   PMID:30578645   PMID:30770454   PMID:31201238   PMID:31491724   PMID:31813798   PMID:31843520   PMID:31862843  
PMID:32001436   PMID:32348770   PMID:32433949   PMID:32661362   PMID:32982660   PMID:33060561   PMID:33106431   PMID:33380173   PMID:33591268   PMID:33649223   PMID:33795231   PMID:33938911  
PMID:34129836   PMID:34157307   PMID:34174788   PMID:34380645   PMID:34434211   PMID:34809449   PMID:34822715   PMID:34921112   PMID:35020897   PMID:35320729   PMID:35377797   PMID:35793630  
PMID:35858332   PMID:35978192   PMID:36093048   PMID:36683433   PMID:37300483   PMID:37385754   PMID:37702066   PMID:37871574   PMID:38112574   PMID:38326607   PMID:38355793   PMID:38776918  


Genomics

Comparative Map Data
Id3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394135,871,133 - 135,872,703 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4135,870,808 - 135,873,066 (+)EnsemblGRCm39 Ensembl
GRCm384136,143,822 - 136,145,392 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4136,143,497 - 136,145,755 (+)EnsemblGRCm38mm10GRCm38
MGSCv374135,699,737 - 135,701,307 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364135,415,898 - 135,417,463 (+)NCBIMGSCv36mm8
Celera4134,340,192 - 134,341,762 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map468.34NCBI
ID3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38123,557,926 - 23,559,501 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl123,557,926 - 23,559,501 (-)EnsemblGRCh38hg38GRCh38
GRCh37123,884,417 - 23,885,992 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36123,756,996 - 23,758,909 (-)NCBINCBI36Build 36hg18NCBI36
Build 34123,629,761 - 23,631,591NCBI
Celera122,214,113 - 22,216,026 (-)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef122,134,776 - 22,136,609 (-)NCBIHuRef
CHM1_1123,997,097 - 23,998,961 (-)NCBICHM1_1
T2T-CHM13v2.0123,392,495 - 23,394,070 (-)NCBIT2T-CHM13v2.0
Id3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85153,656,253 - 153,657,860 (+)NCBIGRCr8
mRatBN7.25148,372,784 - 148,374,353 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5148,372,762 - 148,374,349 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5151,069,678 - 151,071,250 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05152,843,951 - 152,845,523 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05152,825,974 - 152,827,546 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05154,489,603 - 154,491,172 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,489,590 - 154,491,223 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05158,263,323 - 158,264,892 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45154,934,138 - 154,935,707 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15154,944,176 - 154,945,745 (+)NCBI
Celera5146,776,457 - 146,778,028 (+)NCBICelera
RH 3.4 Map51002.7RGD
Cytogenetic Map5q36NCBI
Id3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554523,537,021 - 3,560,954 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554523,537,352 - 3,538,921 (-)NCBIChiLan1.0ChiLan1.0
ID3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21203,379,403 - 203,384,318 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11202,485,663 - 202,487,260 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0122,748,714 - 22,750,582 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1123,734,263 - 23,736,175 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl123,734,263 - 23,736,175 (-)Ensemblpanpan1.1panPan2
ID3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,880,659 - 75,881,786 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,880,657 - 75,882,010 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha272,450,690 - 72,451,818 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0276,440,035 - 76,441,163 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl276,440,029 - 76,441,446 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1273,262,350 - 73,263,478 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,269,394 - 74,270,528 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,274,965 - 75,276,093 (+)NCBIUU_Cfam_GSD_1.0
Id3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505842,933,316 - 42,934,892 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364748,758,030 - 8,759,823 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364748,758,098 - 8,759,684 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ID3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl681,422,546 - 81,424,075 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1681,422,541 - 81,424,169 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ID3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120109,120,403 - 109,122,269 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20109,120,691 - 109,123,210 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660337,205,391 - 7,212,042 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Id3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247648,175,372 - 8,177,451 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247648,175,841 - 8,177,444 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Id3
48 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:602
Count of miRNA genes:400
Interacting mature miRNAs:471
Transcripts:ENSMUST00000008016, ENSMUST00000133946, ENSMUST00000151001
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301793Tlsr3_mthymic lymphoma suppressor region 3 (mouse)Not determined4129465811136864536Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
4142082Psds2_mpsoriasis-like skin disease severity 2 (mouse)Not determined4133154678137617995Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131650724140879275Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse

Markers in Region
Id3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,140,504 - 136,140,623UniSTSGRCm38
MGSCv374135,696,419 - 135,696,538UniSTSGRCm37
Celera4134,336,875 - 134,336,994UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.0UniSTS
UniSTS:235067  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,143,928 - 136,144,014UniSTSGRCm38
MGSCv374135,699,843 - 135,699,929UniSTSGRCm37
Celera4134,340,298 - 134,340,384UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.0UniSTS
Idb3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D3UniSTS
cM Map466.0UniSTS
PMC305683P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,143,879 - 136,144,353UniSTSGRCm38
MGSCv374135,699,794 - 135,700,268UniSTSGRCm37
Celera4134,340,249 - 134,340,723UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.0UniSTS
MARC_5735-5736:996690763:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,144,082 - 136,144,352UniSTSGRCm38
MGSCv374135,699,997 - 135,700,267UniSTSGRCm37
Celera4134,340,452 - 134,340,722UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.0UniSTS
PMC133998P6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,143,879 - 136,144,350UniSTSGRCm38
MGSCv374135,699,794 - 135,700,265UniSTSGRCm37
Celera4134,340,249 - 134,340,720UniSTS
Cytogenetic Map4D3UniSTS
cM Map466.0UniSTS
Id3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,144,975 - 136,145,727UniSTSGRCm38
MGSCv374135,700,890 - 135,701,642UniSTSGRCm37
Celera4134,341,345 - 134,342,097UniSTS
Cytogenetic Map4D3UniSTS
Id3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384136,143,882 - 136,144,377UniSTSGRCm38
MGSCv374135,699,797 - 135,700,292UniSTSGRCm37
Celera4134,340,252 - 134,340,747UniSTS
Cytogenetic Map4D3UniSTS
Id3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D3UniSTS
Id3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D3UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001429353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI173823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL935264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M60523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M60524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000008016   ⟹   ENSMUSP00000008016
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4135,870,808 - 135,872,703 (+)Ensembl
GRCm38.p6 Ensembl4136,143,497 - 136,145,392 (+)Ensembl
Ensembl Acc Id: ENSMUST00000133946
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4135,872,285 - 135,873,066 (+)Ensembl
GRCm38.p6 Ensembl4136,144,974 - 136,145,755 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151001
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4135,871,175 - 135,872,027 (+)Ensembl
GRCm38.p6 Ensembl4136,143,864 - 136,144,716 (+)Ensembl
RefSeq Acc Id: NM_008321   ⟹   NP_032347
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394135,871,133 - 135,872,703 (+)NCBI
GRCm384136,143,822 - 136,145,392 (+)ENTREZGENE
MGSCv374135,699,737 - 135,701,307 (+)RGD
Celera4134,340,192 - 134,341,762 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032347   ⟸   NM_008321
- UniProtKB: P41133 (UniProtKB/Swiss-Prot),   Q545W1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000008016   ⟸   ENSMUST00000008016
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P41133-F1-model_v2 AlphaFold P41133 1-119 view protein structure

Promoters
RGD ID:6835488
Promoter ID:MM_KWN:40197
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000022874,   OTTMUST00000022875,   UC008VHS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364135,698,746 - 135,699,957 (+)MPROMDB
RGD ID:6885102
Promoter ID:EPDNEW_M6002
Type:multiple initiation site
Name:Id3_1
Description:Mus musculus inhibitor of DNA binding 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384136,143,824 - 136,143,884EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96398 AgrOrtholog
Ensembl Genes ENSMUSG00000007872 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000008016 ENTREZGENE
  ENSMUST00000008016.3 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA-bd_prot-inh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96398 ENTREZGENE
NCBI Gene 15903 ENTREZGENE
PANTHER DNA-BINDING PROTEIN INHIBITOR ID-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11723 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Id3 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ID3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q545W1 ENTREZGENE, UniProtKB/TrEMBL