Fgf8 (fibroblast growth factor 8) - Rat Genome Database

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Gene: Fgf8 (fibroblast growth factor 8) Mus musculus
Analyze
Symbol: Fgf8
Name: fibroblast growth factor 8
RGD ID: 1553752
MGI Page MGI
Description: Predicted to enable signaling receptor binding activity. Involved in outflow tract septum morphogenesis. Acts upstream of or within several processes, including brain development; circulatory system development; and embryonic morphogenesis. Predicted to be located in external side of plasma membrane. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; branchial arch; embryo ectoderm; embryo mesenchyme; and sensory organ. Used to study DiGeorge syndrome and tetralogy of Fallot. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 6 with or without anosmia and prostate carcinoma in situ. Orthologous to human FGF8 (fibroblast growth factor 8).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ai; Aigf; androgen-induced growth factor; Fgf-8; Fgf6c; fibroblast growth factor 6c; HBGF-8; heparin-binding growth factor 8; MGC59627
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391945,724,930 - 45,731,380 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1945,725,237 - 45,731,354 (-)EnsemblGRCm39 Ensembl
GRCm381945,736,491 - 45,742,941 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1945,736,798 - 45,742,915 (-)EnsemblGRCm38mm10GRCm38
MGSCv371945,811,288 - 45,817,374 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361945,790,129 - 45,796,184 (-)NCBIMGSCv36mm8
Celera1946,499,127 - 46,505,223 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1938.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aorta morphogenesis  (IGI)
apoptotic process  (IGI,IMP)
blood vessel remodeling  (IGI)
bone development  (ISO)
branching involved in blood vessel morphogenesis  (IGI)
branching involved in salivary gland morphogenesis  (IGI,IMP)
branching involved in ureteric bud morphogenesis  (IMP)
cell differentiation  (IEA)
cell fate commitment  (IGI)
cell migration involved in mesendoderm migration  (IMP)
cell population proliferation  (IGI,IMP)
cell proliferation in forebrain  (IMP)
central nervous system neuron development  (ISO)
corticotropin hormone secreting cell differentiation  (IDA)
determination of left/right symmetry  (IMP)
dopaminergic neuron differentiation  (ISO,TAS)
dorsal/ventral axon guidance  (ISO)
dorsal/ventral pattern formation  (IBA)
embryo development ending in birth or egg hatching  (IMP)
embryonic heart tube development  (IBA,IMP)
embryonic hindlimb morphogenesis  (IGI)
embryonic neurocranium morphogenesis  (IGI)
epithelial to mesenchymal transition involved in endocardial cushion formation  (IDA,IMP)
fibroblast growth factor receptor signaling pathway  (IBA,IDA,IMP,ISO)
forebrain dorsal/ventral pattern formation  (IMP)
forebrain morphogenesis  (IMP)
forebrain neuron development  (ISO)
generation of neurons  (IMP)
gonad development  (ISO)
heart development  (IMP)
heart looping  (IMP)
heart morphogenesis  (IBA,IMP)
inner ear morphogenesis  (IGI)
kidney development  (IMP)
larynx morphogenesis  (IGI)
limb morphogenesis  (IBA,IGI)
lung development  (IMP)
lung morphogenesis  (IMP)
male genitalia development  (IDA)
MAPK cascade  (IMP)
mesodermal cell migration  (IMP)
mesonephros development  (ISO)
metanephros development  (ISO)
midbrain-hindbrain boundary development  (IMP)
mitotic nuclear division  (IDA)
motor neuron axon guidance  (ISO)
negative regulation of apoptotic process  (IGI,IMP)
negative regulation of cardiac muscle tissue development  (ISO)
negative regulation of neuron apoptotic process  (IMP)
neural plate morphogenesis  (IMP)
neuroepithelial cell differentiation  (ISO)
neuron apoptotic process  (IMP)
neuron differentiation  (IBA)
odontogenesis  (ISO)
organ growth  (IGI,IMP)
organ induction  (IGI)
otic vesicle formation  (IGI,TAS)
outflow tract morphogenesis  (IGI)
outflow tract septum morphogenesis  (IGI)
pallium development  (IMP)
pharyngeal system development  (IGI)
positive regulation of cell division  (IEA)
positive regulation of cell population proliferation  (IBA,IDA,IMP,ISO)
positive regulation of ERK1 and ERK2 cascade  (IGI)
positive regulation of G protein-coupled receptor signaling pathway  (IDA)
positive regulation of gene expression  (IBA,IDA,IGI,IMP)
positive regulation of mitotic nuclear division  (IDA)
positive regulation of organ growth  (IGI,IMP)
positive regulation of peptidyl-tyrosine phosphorylation  (IMP)
positive regulation of protein phosphorylation  (IBA)
positive regulation of stem cell proliferation  (IGI)
regulation of cell migration  (IBA)
regulation of odontogenesis of dentin-containing tooth  (IGI)
response to organic cyclic compound  (ISO)
response to oxidative stress  (ISO)
response to xenobiotic stimulus  (ISO)
signal transduction involved in regulation of gene expression  (IDA)
stem cell proliferation  (IGI)
subpallium development  (IMP)
telencephalon development  (IMP)
thyroid gland development  (IGI,IMP)
thyroid-stimulating hormone-secreting cell differentiation  (IDA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
aberrant origin of the right subclavian artery  (IAGP)
abnormal allantois morphology  (IAGP)
abnormal amnion morphology  (IAGP)
abnormal aortic arch development  (IAGP)
abnormal aortic arch morphology  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal brain development  (IAGP)
abnormal brain morphology  (IAGP)
abnormal cardiac epithelial to mesenchymal transition  (IAGP)
abnormal cardiac neural crest cell migration  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cardiogenic mesoderm morphology  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal cerebellum anterior vermis morphology  (IAGP)
abnormal cerebellum vermis morphology  (IAGP)
abnormal chorion morphology  (IAGP)
abnormal cochlear sensory epithelium morphology  (IAGP)
abnormal common carotid artery morphology  (IAGP)
abnormal conotruncal ridge morphology  (IAGP)
abnormal coronary artery morphology  (IAGP)
abnormal coronary vessel morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal digit development  (IAGP)
abnormal digit morphology  (IAGP)
abnormal ectoderm development  (IAGP)
abnormal embryonic epiblast morphology  (IAGP)
abnormal eyelid morphology  (IAGP)
abnormal forebrain development  (IAGP)
abnormal forelimb stylopod morphology  (IAGP)
abnormal forelimb zeugopod morphology  (IAGP)
abnormal fourth pharyngeal arch artery morphology  (IAGP)
abnormal gait  (IAGP)
abnormal heart development  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart right ventricle morphology  (IAGP)
abnormal heart tube morphology  (IAGP)
abnormal hindlimb stylopod morphology  (IAGP)
abnormal hindlimb zeugopod morphology  (IAGP)
abnormal hypothalamus morphology  (IAGP)
abnormal internal carotid artery morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal limb bud morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal limb morphology  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal maxilla morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal midbrain morphology  (IAGP)
abnormal midface morphology  (IAGP)
abnormal nasal pit morphology  (IAGP)
abnormal neural crest cell apoptosis  (IAGP)
abnormal neural crest cell migration  (IAGP)
abnormal neural crest cell morphology  (IAGP)
abnormal neural fold formation  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal neuron apoptosis  (IAGP)
abnormal parathyroid gland morphology  (IAGP)
abnormal patterning of the organ of Corti  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal pharyngeal arch mesenchyme morphology  (IAGP)
abnormal pharyngeal arch morphology  (IAGP)
abnormal pillar cell differentiation  (IAGP)
abnormal pillar cell morphology  (IAGP)
abnormal pituitary gland morphology  (IAGP)
abnormal primitive streak elongation  (IAGP)
abnormal primitive streak morphology  (IAGP)
abnormal Purkinje cell morphology  (IAGP)
abnormal Raphe nucleus morphology  (IAGP)
abnormal reproductive system morphology  (IAGP)
abnormal rhombomere morphology  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal serotonergic neuron morphology  (IAGP)
abnormal sixth pharyngeal arch artery morphology  (IAGP)
abnormal somite development  (IAGP)
abnormal splanchnic mesoderm morphology  (IAGP)
abnormal subclavian artery morphology  (IAGP)
abnormal substantia nigra morphology  (IAGP)
abnormal third pharyngeal arch artery morphology  (IAGP)
abnormal thymus development  (IAGP)
abnormal thymus morphology  (IAGP)
abnormal trigeminal nerve morphology  (IAGP)
abnormal truncus arteriosus septation  (IAGP)
abnormal ureteric bud morphology  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
absent cardiac outflow tract  (IAGP)
absent cerebellum  (IAGP)
absent forelimb  (IAGP)
absent fourth pharyngeal arch artery  (IAGP)
absent heart  (IAGP)
absent heart right ventricle  (IAGP)
absent hindlimb  (IAGP)
absent incus  (IAGP)
absent inferior colliculus  (IAGP)
absent kidney  (IAGP)
absent Meckel's cartilage  (IAGP)
absent mesoderm  (IAGP)
absent molars  (IAGP)
absent olfactory bulb  (IAGP)
absent parathyroid glands  (IAGP)
absent pillar cells  (IAGP)
absent primitive node  (IAGP)
absent radius  (IAGP)
absent renal glomerulus  (IAGP)
absent sixth pharyngeal arch artery  (IAGP)
absent somites  (IAGP)
aortic dissection  (IAGP)
atrial septal defect  (IAGP)
bicuspid aortic valve  (IAGP)
bicuspid pulmonary valve  (IAGP)
cervical aortic arch  (IAGP)
cleft primary palate  (IAGP)
common atrium  (IAGP)
common ventricle  (IAGP)
cyanosis  (IAGP)
decreased body weight  (IAGP)
decreased cell proliferation  (IAGP)
decreased dopaminergic neuron number  (IAGP)
decreased embryo size  (IAGP)
decreased heart right ventricle size  (IAGP)
decreased inferior colliculus size  (IAGP)
decreased mitotic index  (IAGP)
decreased neuron apoptosis  (IAGP)
decreased pulmonary respiratory rate  (IEA)
decreased tongue size  (IAGP)
dilated heart atrium  (IAGP)
dilated heart left ventricle  (IAGP)
double outlet right ventricle  (IAGP)
ectopic parathyroid gland  (IAGP)
ectopic thymus  (IAGP)
edema  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality prior to tooth bud stage  (IEA)
enlarged tectum  (IAGP)
enlarged third pharyngeal arch artery  (IAGP)
fetal growth retardation  (IAGP)
fourth pharyngeal arch artery hypoplasia  (IAGP)
fused tarsal bones  (IAGP)
impaired branching involved in ureteric bud morphogenesis  (IAGP)
impaired hearing  (IAGP)
increased apoptosis  (IAGP)
increased kidney apoptosis  (IAGP)
increased neuron apoptosis  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
interrupted aortic arch  (IAGP)
kidney failure  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
oligodactyly  (IAGP)
open neural tube  (IAGP)
parathyroid hypoplasia  (IAGP)
pericardial effusion  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
persistent truncus arteriosis  (IAGP)
pharyngeal arch hypoplasia  (IAGP)
polysyndactyly  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
retroesophageal right subclavian artery  (IAGP)
right aortic arch  (IAGP)
second pharyngeal arch hypoplasia  (IAGP)
short limbs  (IAGP)
small cerebellum  (IAGP)
small ears  (IAGP)
small embryonic telencephalon  (IAGP)
small first pharyngeal arch  (IAGP)
small limb buds  (IAGP)
small mandible  (IAGP)
small pharyngeal arch  (IAGP)
small thymus  (IAGP)
syndactyly  (IAGP)
third pharyngeal arch artery hypoplasia  (IAGP)
third pharyngeal arch hypoplasia  (IAGP)
thymus hypoplasia  (IAGP)
transposition of great arteries  (IAGP)
unilateral cleft palate  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MMTV-Fgf8 transgenic mice develop mammary and salivary gland neoplasia and ovarian stromal hyperplasia. Daphna-Iken D, etal., Oncogene. 1998 Nov 26;17(21):2711-7.
2. FGF8 isoform b expression in human prostate cancer. Gnanapragasam VJ, etal., Br J Cancer. 2003 May 6;88(9):1432-8.
3. Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells. Kury P, etal., Development 1997 Mar;124(6):1251-62.
4. Increased expression of fibroblast growth factor 8 in human breast cancer. Marsh SK, etal., Oncogene. 1999 Jan 28;18(4):1053-60.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Fibroblast growth factor 8 isoform B overexpression in prostate epithelium: a new mouse model for prostatic intraepithelial neoplasia. Song Z, etal., Cancer Res. 2002 Sep 1;62(17):5096-105.
14. Predominant expression of fibroblast growth factor (FGF) 8, FGF4, and FGF receptor 1 in nonseminomatous and highly proliferative components of testicular germ cell tumors. Suzuki K, etal., Virchows Arch. 2001 Nov;439(5):616-21.
15. Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis. Uchii M, etal., Arthritis Res Ther. 2008;10(4):R90. Epub 2008 Aug 12.
16. Expression of fibroblast growth factor (FGF)-8 isoforms and FGF receptors in human ovarian tumors. Valve E, etal., Int J Cancer. 2000 Dec 1;88(5):718-25.
17. Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer. Valve EM, etal., Lab Invest. 2001 Jun;81(6):815-26.
18. Correlation between androgen receptor expression and FGF8 mRNA levels in patients with prostate cancer and benign prostatic hypertrophy. Wang Q, etal., J Clin Pathol. 1999 Jan;52(1):29-34.
19. Molecular and toxicologic research in newborn hypospadiac male rats following in utero exposure to di-n-butyl phthalate (DBP). Zhu YJ, etal., Toxicology. 2009 Jun 16;260(1-3):120-5. Epub 2009 Apr 5.
Additional References at PubMed
PMID:1409588   PMID:7583127   PMID:7588050   PMID:7737407   PMID:7749227   PMID:7761105   PMID:7768185   PMID:7862157   PMID:7873403   PMID:7884899   PMID:7980556   PMID:8290257  
PMID:8575323   PMID:8582274   PMID:8585128   PMID:8601591   PMID:8645626   PMID:8660860   PMID:8661131   PMID:8684466   PMID:8792608   PMID:8837770   PMID:8848044   PMID:8883961  
PMID:8901049   PMID:8922528   PMID:9006074   PMID:9013630   PMID:9056772   PMID:9107690   PMID:9152009   PMID:9159136   PMID:9177783   PMID:9205106   PMID:9226442   PMID:9226455  
PMID:9244299   PMID:9247260   PMID:9247335   PMID:9256345   PMID:9256466   PMID:9332670   PMID:9338782   PMID:9342056   PMID:9362463   PMID:9385055   PMID:9405645   PMID:9408977  
PMID:9415428   PMID:9417918   PMID:9428417   PMID:9435295   PMID:9438343   PMID:9462741   PMID:9463347   PMID:9463360   PMID:9486536   PMID:9520113   PMID:9521907   PMID:9529255  
PMID:9531541   PMID:9570771   PMID:9584130   PMID:9598348   PMID:9620767   PMID:9620855   PMID:9630220   PMID:9631179   PMID:9636075   PMID:9651475   PMID:9651520   PMID:9680378  
PMID:9689088   PMID:9712518   PMID:9716414   PMID:9729491   PMID:9733575   PMID:9753686   PMID:9778510   PMID:9784490   PMID:9790191   PMID:9806931   PMID:9834182   PMID:9834185  
PMID:9847236   PMID:9882503   PMID:9883582   PMID:9895322   PMID:9916808   PMID:9988217   PMID:10021340   PMID:10021368   PMID:10026229   PMID:10049363   PMID:10051411   PMID:10079220  
PMID:10079223   PMID:10079236   PMID:10087301   PMID:10090727   PMID:10098408   PMID:10191046   PMID:10192400   PMID:10196374   PMID:10199636   PMID:10199963   PMID:10227293   PMID:10227294  
PMID:10330496   PMID:10349636   PMID:10354469   PMID:10373120   PMID:10381577   PMID:10398531   PMID:10409502   PMID:10411502   PMID:10415326   PMID:10421635   PMID:10431240   PMID:10433923  
PMID:10441736   PMID:10470645   PMID:10471509   PMID:10477299   PMID:10490024   PMID:10498682   PMID:10498685   PMID:10499585   PMID:10499586   PMID:10512182   PMID:10518210   PMID:10518487  
PMID:10518490   PMID:10518499   PMID:10529425   PMID:10534614   PMID:10534616   PMID:10601039   PMID:10602987   PMID:10603081   PMID:10625557   PMID:10642790   PMID:10642791   PMID:10662503  
PMID:10662638   PMID:10704889   PMID:10716450   PMID:10751172   PMID:10753507   PMID:10769235   PMID:10802662   PMID:10804184   PMID:10804187   PMID:10835630   PMID:10882526   PMID:10887078  
PMID:10920228   PMID:10964471   PMID:10976045   PMID:11017084   PMID:11029008   PMID:11042159   PMID:11076861   PMID:11101845   PMID:11101846   PMID:11118883   PMID:11124114   PMID:11133159  
PMID:11144352   PMID:11146506   PMID:11152636   PMID:11157065   PMID:11165488   PMID:11171400   PMID:11180951   PMID:11217851   PMID:11291863   PMID:11291865   PMID:11335076   PMID:11336496  
PMID:11358868   PMID:11412024   PMID:11418863   PMID:11430695   PMID:11470817   PMID:11476582   PMID:11493522   PMID:11493561   PMID:11500373   PMID:11509733   PMID:11532426   PMID:11532916  
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PMID:11731698   PMID:11748135   PMID:11784076   PMID:11795391   PMID:11820816   PMID:11823447   PMID:11846474   PMID:11850178   PMID:11890684   PMID:11892011   PMID:11900978   PMID:11922976  
PMID:11953986   PMID:11955708   PMID:11960706   PMID:11973313   PMID:12000792   PMID:12004962   PMID:12074550   PMID:12086465   PMID:12117807   PMID:12142027   PMID:12152071   PMID:12175489  
PMID:12193642   PMID:12194867   PMID:12217322   PMID:12223415   PMID:12223416   PMID:12223417   PMID:12351180   PMID:12361961   PMID:12367504   PMID:12381664   PMID:12397106   PMID:12399319  
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PMID:12913075   PMID:12915301   PMID:12915315   PMID:12915318   PMID:12917333   PMID:12921747   PMID:12923052   PMID:12925582   PMID:12941622   PMID:12952897   PMID:12966207   PMID:12971989  
PMID:13129926   PMID:14502576   PMID:14505572   PMID:14511481   PMID:14526104   PMID:14567981   PMID:14585979   PMID:14597661   PMID:14602678   PMID:14602679   PMID:14605369   PMID:14623818  
PMID:14623825   PMID:14623826   PMID:14623956   PMID:14645126   PMID:14651936   PMID:14667410   PMID:14668414   PMID:14681194   PMID:14681479   PMID:14727108   PMID:14749824   PMID:14761650  
PMID:14761651   PMID:14975726   PMID:14981518   PMID:15013800   PMID:15030763   PMID:15037319   PMID:15039943   PMID:15042696   PMID:15053978   PMID:15063181   PMID:15069081   PMID:15071597  
PMID:15081361   PMID:15084457   PMID:15105370   PMID:15108315   PMID:15121182   PMID:15136723   PMID:15142971   PMID:15147765   PMID:15183723   PMID:15196959   PMID:15201220   PMID:15201223  
PMID:15201224   PMID:15201225   PMID:15207855   PMID:15242796   PMID:15255957   PMID:15294144   PMID:15326356   PMID:15328019   PMID:15340846   PMID:15363409   PMID:15371312   PMID:15384171  
PMID:15469978   PMID:15470137   PMID:15483110   PMID:15509764   PMID:15537664   PMID:15572144   PMID:15576405   PMID:15580630   PMID:15581864   PMID:15601856   PMID:15615879   PMID:15623804  
PMID:15634692   PMID:15652703   PMID:15677727   PMID:15680353   PMID:15680361   PMID:15716346   PMID:15729686   PMID:15731404   PMID:15741321   PMID:15750184   PMID:15788460   PMID:15789410  
PMID:15790971   PMID:15809037   PMID:15829518   PMID:15830353   PMID:15830372   PMID:15843406   PMID:15843411   PMID:15843414   PMID:15843416   PMID:15857913   PMID:15857914   PMID:15870281  
PMID:15880584   PMID:15889083   PMID:15893304   PMID:15901664   PMID:15917450   PMID:15930102   PMID:15936012   PMID:15963767   PMID:15973411   PMID:15973734   PMID:15996652   PMID:16014716  
PMID:16015334   PMID:16040801   PMID:16049111   PMID:16049112   PMID:16054034   PMID:16109169   PMID:16120640   PMID:16123981   PMID:16127714   PMID:16141072   PMID:16141073   PMID:16169548  
PMID:16172976   PMID:16192310   PMID:16207730   PMID:16207751   PMID:16221730   PMID:16236767   PMID:16243425   PMID:16245339   PMID:16252261   PMID:16267092   PMID:16284121   PMID:16284245  
PMID:16284942   PMID:16291788   PMID:16308330   PMID:16309667   PMID:16339193   PMID:16368932   PMID:16397882   PMID:16397896   PMID:16399079   PMID:16399080   PMID:16423343   PMID:16439448  
PMID:16452092   PMID:16458284   PMID:16467359   PMID:16469766   PMID:16470835   PMID:16489341   PMID:16492970   PMID:16495310   PMID:16508948   PMID:16524929   PMID:16530750   PMID:16530751  
PMID:16556916   PMID:16571630   PMID:16571633   PMID:16602821   PMID:16613831   PMID:16630606   PMID:16641368   PMID:16644143   PMID:16647303   PMID:16651541   PMID:16672333   PMID:16687131  
PMID:16687132   PMID:16696966   PMID:16715082   PMID:16720879   PMID:16720880   PMID:16728477   PMID:16728479   PMID:16741229   PMID:16751104   PMID:16765933   PMID:16765936   PMID:16782087  
PMID:16783635   PMID:16788063   PMID:16806156   PMID:16818445   PMID:16839542   PMID:16855091   PMID:16887818   PMID:16900517   PMID:16914493   PMID:16922921   PMID:16950123   PMID:16964442  
PMID:16971467   PMID:17000704   PMID:17023412   PMID:17036046   PMID:17067568   PMID:17075876   PMID:17079275   PMID:17107664   PMID:17117437   PMID:17117439   PMID:17119023   PMID:17126317  
PMID:17127040   PMID:17150206   PMID:17164422   PMID:17166916   PMID:17173889   PMID:17194222   PMID:17195184   PMID:17207476   PMID:17222543   PMID:17241623   PMID:17314325   PMID:17325035  
PMID:17344228   PMID:17360443   PMID:17360769   PMID:17360777   PMID:17366625   PMID:17367776   PMID:17371845   PMID:17394220   PMID:17442300   PMID:17442747   PMID:17467687   PMID:17468181  
PMID:17470284   PMID:17473173   PMID:17481601   PMID:17490632   PMID:17507393   PMID:17509151   PMID:17515859   PMID:17519333   PMID:17535249   PMID:17537789   PMID:17537797   PMID:17537800  
PMID:17544391   PMID:17553902   PMID:17557302   PMID:17588959   PMID:17601531   PMID:17602894   PMID:17611225   PMID:17628018   PMID:17634195   PMID:17654705   PMID:17668378   PMID:17687036  
PMID:17688467   PMID:17697936   PMID:17699604   PMID:17707671   PMID:17714700   PMID:17728342   PMID:17828260   PMID:17878916   PMID:17880938   PMID:17904116   PMID:17911046   PMID:17951031  
PMID:17959802   PMID:17964566   PMID:17965051   PMID:17980036   PMID:17984064   PMID:18000065   PMID:18039967   PMID:18043734   PMID:18045842   PMID:18058912   PMID:18067586   PMID:18094024  
PMID:18157121   PMID:18171685   PMID:18213582   PMID:18216176   PMID:18241853   PMID:18257070   PMID:18265010   PMID:18268105   PMID:18272352   PMID:18280296   PMID:18280464   PMID:18329011  
PMID:18330926   PMID:18331719   PMID:18334251   PMID:18353862   PMID:18359901   PMID:18386787   PMID:18403408   PMID:18429041   PMID:18448090   PMID:18449196   PMID:18452488   PMID:18459137  
PMID:18462697   PMID:18462699   PMID:18480159   PMID:18480279   PMID:18495356   PMID:18498088   PMID:18498097   PMID:18498101   PMID:18505822   PMID:18539921   PMID:18547559   PMID:18566132  
PMID:18572160   PMID:18579682   PMID:18586087   PMID:18594511   PMID:18596921   PMID:18617531   PMID:18625063   PMID:18634775   PMID:18653561   PMID:18694563   PMID:18697220   PMID:18723448  
PMID:18729207   PMID:18775421   PMID:18781635   PMID:18794329   PMID:18818193   PMID:18818376   PMID:18832392   PMID:18835578   PMID:18929642   PMID:18930042   PMID:18942154   PMID:18974875  
PMID:18981480   PMID:19000668   PMID:19013147   PMID:19017795   PMID:19027001   PMID:19046160   PMID:19056886   PMID:19059364   PMID:19093031   PMID:19103193   PMID:19103755   PMID:19153222  
PMID:19168674   PMID:19192266   PMID:19210962   PMID:19211672   PMID:19229034   PMID:19235731   PMID:19248778   PMID:19252479   PMID:19253341   PMID:19297409   PMID:19298015   PMID:19298856  
PMID:19304889   PMID:19307307   PMID:19339600   PMID:19357274   PMID:19383632   PMID:19383871   PMID:19386268   PMID:19386269   PMID:19389367   PMID:19389368   PMID:19390486   PMID:19422820  
PMID:19429790   PMID:19439426   PMID:19464179   PMID:19477957   PMID:19479951   PMID:19500387   PMID:19509466   PMID:19527706   PMID:19539783   PMID:19540218   PMID:19544582   PMID:19553355  
PMID:19555770   PMID:19591819   PMID:19592577   PMID:19603509   PMID:19607792   PMID:19615442   PMID:19619645   PMID:19660449   PMID:19700620   PMID:19700621   PMID:19705442   PMID:19705445  
PMID:19715689   PMID:19732411   PMID:19732765   PMID:19766620   PMID:19777594   PMID:19783740   PMID:19786569   PMID:19793884   PMID:19793886   PMID:19795519   PMID:19796621   PMID:19820185  
PMID:19842188   PMID:19846726   PMID:19853565   PMID:19855134   PMID:19877283   PMID:19900438   PMID:19906845   PMID:19906857   PMID:19906863   PMID:19906864   PMID:19913006   PMID:19922873  
PMID:19956724   PMID:19968985   PMID:20018673   PMID:20034106   PMID:20035084   PMID:20040495   PMID:20040496   PMID:20040500   PMID:20043884   PMID:20110535   PMID:20111592   PMID:20122914  
PMID:20152827   PMID:20159597   PMID:20206242   PMID:20212115   PMID:20214979   PMID:20215350   PMID:20230754   PMID:20237272   PMID:20335360   PMID:20347762   PMID:20348033   PMID:20359476  
PMID:20370578   PMID:20404326   PMID:20405041   PMID:20450902   PMID:20457670   PMID:20459789   PMID:20471971   PMID:20493948   PMID:20501333   PMID:20503368   PMID:20532162   PMID:20533405  
PMID:20553372   PMID:20573694   PMID:20596238   PMID:20606007   PMID:20630950   PMID:20637190   PMID:20653027   PMID:20661473   PMID:20668538   PMID:20685737   PMID:20702562   PMID:20727874  
PMID:20730911   PMID:20732316   PMID:20801112   PMID:20807544   PMID:20816794   PMID:20826531   PMID:20826535   PMID:20843859   PMID:20845426   PMID:20876279   PMID:20876643   PMID:20883686  
PMID:20920500   PMID:20934421   PMID:20944551   PMID:20962035   PMID:21034500   PMID:21045211   PMID:21046478   PMID:21070765   PMID:21074523   PMID:21076617   PMID:21087601   PMID:21089306  
PMID:21098569   PMID:21098571   PMID:21106844   PMID:21145498   PMID:21172336   PMID:21177346   PMID:21183473   PMID:21228006   PMID:21237142   PMID:21246653   PMID:21246658   PMID:21256124  
PMID:21266408   PMID:21267068   PMID:21289193   PMID:21292980   PMID:21307092   PMID:21307096   PMID:21309073   PMID:21331042   PMID:21360789   PMID:21364285   PMID:21368122   PMID:21377456  
PMID:21382375   PMID:21383175   PMID:21384471   PMID:21412937   PMID:21445260   PMID:21448975   PMID:21465616   PMID:21466802   PMID:21471156   PMID:21490064   PMID:21494559   PMID:21506104  
PMID:21538808   PMID:21571225   PMID:21596839   PMID:21600200   PMID:21636786   PMID:21655085   PMID:21664901   PMID:21677750   PMID:21693517   PMID:21725307   PMID:21731673   PMID:21750036  
PMID:21750544   PMID:21752813   PMID:21761482   PMID:21768372   PMID:21795281   PMID:21795391   PMID:21799763   PMID:21831921   PMID:21832120   PMID:21839920   PMID:21858141   PMID:21865321  
PMID:21871565   PMID:21873635   PMID:21876757   PMID:21880902   PMID:21896659   PMID:21924961   PMID:21925158   PMID:21925604   PMID:21930923   PMID:21937598   PMID:21968101   PMID:21982646  
PMID:22007134   PMID:22040872   PMID:22072575   PMID:22102609   PMID:22110055   PMID:22116936   PMID:22147889   PMID:22174793   PMID:22178153   PMID:22186731   PMID:22234613   PMID:22235191  
PMID:22240098   PMID:22278983   PMID:22292060   PMID:22340494   PMID:22354888   PMID:22371266   PMID:22377357   PMID:22383895   PMID:22387309   PMID:22404534   PMID:22411303   PMID:22432025  
PMID:22438573   PMID:22461561   PMID:22465097   PMID:22465667   PMID:22479201   PMID:22479388   PMID:22484060   PMID:22492355   PMID:22573616   PMID:22623663   PMID:22658483   PMID:22662233  
PMID:22669107   PMID:22674535   PMID:22682244   PMID:22718343   PMID:22792203   PMID:22819339   PMID:22819676   PMID:22889265   PMID:22902740   PMID:22912414   PMID:22912418   PMID:22912798  
PMID:22923088   PMID:22939930   PMID:22945632   PMID:22954964   PMID:22993445   PMID:23028455   PMID:23028704   PMID:23034633   PMID:23041116   PMID:23041177   PMID:23042737   PMID:23055936  
PMID:23056351   PMID:23071453   PMID:23085236   PMID:23112163   PMID:23193000   PMID:23201021   PMID:23213408   PMID:23213437   PMID:23213481   PMID:23293024   PMID:23322300   PMID:23332756  
PMID:23358455   PMID:23361844   PMID:23362348   PMID:23382810   PMID:23390542   PMID:23396189   PMID:23444360   PMID:23453598   PMID:23469192   PMID:23471918   PMID:23473983   PMID:23536097  
PMID:23552073   PMID:23553814   PMID:23555292   PMID:23578930   PMID:23584732   PMID:23592779   PMID:23614009   PMID:23618354   PMID:23623500   PMID:23633510   PMID:23633963   PMID:23643382  
PMID:23651855   PMID:23661808   PMID:23674600   PMID:23690951   PMID:23744351   PMID:23747598   PMID:23749471   PMID:23762375   PMID:23763947   PMID:23791818   PMID:23806618   PMID:23818325  
PMID:23872235   PMID:23874217   PMID:23892366   PMID:23900075   PMID:23913870   PMID:23935987   PMID:23942202   PMID:23946445   PMID:23994639   PMID:24003036   PMID:24009529   PMID:24080509  
PMID:24145799   PMID:24170322   PMID:24194600   PMID:24198358   PMID:24218595   PMID:24238961   PMID:24284205   PMID:24335253   PMID:24335256   PMID:24336726   PMID:24348261   PMID:24357321  
PMID:24368733   PMID:24369835   PMID:24370450   PMID:24381197   PMID:24385915   PMID:24403153   PMID:24415953   PMID:24424161   PMID:24431450   PMID:24440154   PMID:24479159   PMID:24482174  
PMID:24501377   PMID:24512770   PMID:24550112   PMID:24569166   PMID:24586731   PMID:24598167   PMID:24599258   PMID:24607228   PMID:24650709   PMID:24680892   PMID:24697898   PMID:24726282  
PMID:24726283   PMID:24785830   PMID:24796693   PMID:24803655   PMID:24812002   PMID:24821700   PMID:24849601   PMID:24909139   PMID:24931720   PMID:24948604   PMID:24952961   PMID:24971735  
PMID:24990742   PMID:24990743   PMID:24992493   PMID:25034710   PMID:25053430   PMID:25053435   PMID:25057208   PMID:25152336   PMID:25166858   PMID:25242040   PMID:25249461   PMID:25302779  
PMID:25336743   PMID:25336744   PMID:25359900   PMID:25381013   PMID:25419850   PMID:25428587   PMID:25448692   PMID:25528224   PMID:25581370   PMID:25617432   PMID:25626636   PMID:25652402  
PMID:25670795   PMID:25742799   PMID:25800090   PMID:25809880   PMID:25813538   PMID:25848055   PMID:25889070   PMID:25889273   PMID:25977363   PMID:25986147   PMID:26071364   PMID:26166575  
PMID:26186931   PMID:26212321   PMID:26220830   PMID:26237517   PMID:26284287   PMID:26295701   PMID:26311466   PMID:26321200   PMID:26387718   PMID:26393505   PMID:26409788   PMID:26441343  
PMID:26441841   PMID:26444681   PMID:26537115   PMID:26545349   PMID:26577899   PMID:26621269   PMID:26658320   PMID:26661618   PMID:26674308   PMID:26685160   PMID:26685326   PMID:26702830  
PMID:26744331   PMID:26748348   PMID:26755636   PMID:26764350   PMID:26764381   PMID:26809587   PMID:26813283   PMID:26826495   PMID:26879466   PMID:26903947   PMID:26959361   PMID:27038343  
PMID:27046536   PMID:27061115   PMID:27065194   PMID:27144312   PMID:27171818   PMID:27256596   PMID:27291295   PMID:27302397   PMID:27395007   PMID:27402846   PMID:27436040   PMID:27453501  
PMID:27506116   PMID:27510750   PMID:27521049   PMID:27578777   PMID:27626380   PMID:27633995   PMID:27732850   PMID:27760115   PMID:27770010   PMID:27827819   PMID:27845689   PMID:27871306  
PMID:27894818   PMID:27992425   PMID:28009287   PMID:28069742   PMID:28087565   PMID:28165338   PMID:28169399   PMID:28177282   PMID:28188179   PMID:28324176   PMID:28333962   PMID:28379358  
PMID:28422959   PMID:28510270   PMID:28511701   PMID:28552557   PMID:28560839   PMID:28579317   PMID:28807898   PMID:28846100   PMID:28893950   PMID:28931923   PMID:28938441   PMID:28961240  
PMID:29028795   PMID:29038301   PMID:29140246   PMID:29158323   PMID:29168693   PMID:29213092   PMID:29229773   PMID:29292497   PMID:29342370   PMID:29352015   PMID:29367466   PMID:29394901  
PMID:29459093   PMID:29615464   PMID:29689292   PMID:29712641   PMID:29729398   PMID:29752281   PMID:29771958   PMID:29866044   PMID:29975682   PMID:30061166   PMID:30116001   PMID:30134070  
PMID:30174317   PMID:30189017   PMID:30190278   PMID:30228991   PMID:30305733   PMID:30352686   PMID:30445565   PMID:30470893   PMID:30559277   PMID:30570432   PMID:30578278   PMID:30592646  
PMID:30638444   PMID:30714224   PMID:30735127   PMID:30787001   PMID:30787437   PMID:30843579   PMID:30872278   PMID:30884041   PMID:31005064   PMID:31038803   PMID:31185200   PMID:31186471  
PMID:31235634   PMID:31260508   PMID:31308417   PMID:31341279   PMID:31361780   PMID:31558711   PMID:31570588   PMID:31748268   PMID:31789450   PMID:31843520   PMID:31896583   PMID:31923383  
PMID:32094117   PMID:32141129   PMID:32156750   PMID:32268095   PMID:32439755   PMID:32450229   PMID:32457899   PMID:32479258   PMID:32521258   PMID:32537491   PMID:32541002   PMID:32561646  
PMID:32597756   PMID:32616504   PMID:32665241   PMID:32692983   PMID:32703236   PMID:32741376   PMID:32753399   PMID:32760291   PMID:32778568   PMID:32907848   PMID:33019532   PMID:33046506  
PMID:33184218   PMID:33210601   PMID:33230114   PMID:33328221   PMID:33469032   PMID:33500317   PMID:33505317   PMID:33568816   PMID:33580754   PMID:33795231   PMID:33871356   PMID:34095148  
PMID:34321664   PMID:34383890   PMID:34423345   PMID:34433009   PMID:34571841   PMID:34601382   PMID:34643182   PMID:34679163   PMID:34722541   PMID:34884468   PMID:34928956   PMID:34929174  
PMID:35020897   PMID:35044299   PMID:35440748   PMID:35508658   PMID:35514236   PMID:35593225   PMID:35618654   PMID:35700056   PMID:35736367   PMID:35781558   PMID:35831953   PMID:35927240  
PMID:35950911   PMID:35951005   PMID:36123354   PMID:36205075   PMID:36512085   PMID:36527791   PMID:36680528   PMID:36745673   PMID:36928426  


Genomics

Comparative Map Data
Fgf8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391945,724,930 - 45,731,380 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1945,725,237 - 45,731,354 (-)EnsemblGRCm39 Ensembl
GRCm381945,736,491 - 45,742,941 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1945,736,798 - 45,742,915 (-)EnsemblGRCm38mm10GRCm38
MGSCv371945,811,288 - 45,817,374 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361945,790,129 - 45,796,184 (-)NCBIMGSCv36mm8
Celera1946,499,127 - 46,505,223 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1938.75NCBI
FGF8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810101,770,109 - 101,780,369 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl10101,770,109 - 101,780,371 (-)EnsemblGRCh38hg38GRCh38
GRCh3710103,529,866 - 103,540,126 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610103,519,877 - 103,525,817 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410103,519,876 - 103,525,817NCBI
Celera1097,268,628 - 97,274,500 (-)NCBICelera
Cytogenetic Map10q24.32NCBI
HuRef1097,160,317 - 97,170,664 (-)NCBIHuRef
CHM1_110103,813,541 - 103,823,715 (-)NCBICHM1_1
T2T-CHM13v2.010102,653,607 - 102,663,864 (-)NCBIT2T-CHM13v2.0
Fgf8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21244,584,477 - 244,590,359 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1244,584,652 - 244,590,359 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1252,726,050 - 252,731,769 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01259,424,173 - 259,429,872 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01252,076,241 - 252,081,969 (-)NCBIRnor_WKY
Rnor_6.01265,492,949 - 265,498,965 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1265,493,124 - 265,498,831 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01272,923,589 - 272,929,296 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41250,951,023 - 250,956,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11251,211,591 - 251,217,299 (-)NCBI
Celera1240,393,901 - 240,399,608 (-)NCBICelera
Cytogenetic Map1q54NCBI
Fgf8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554858,517,412 - 8,521,770 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554858,517,412 - 8,521,732 (+)NCBIChiLan1.0ChiLan1.0
FGF8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan110113,661,598 - 113,668,073 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01098,372,251 - 98,378,811 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110101,844,792 - 101,849,873 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10101,844,792 - 101,853,916 (-)Ensemblpanpan1.1panPan2
FGF8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12814,362,407 - 14,367,109 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2814,362,109 - 14,367,468 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2814,530,980 - 14,536,626 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02814,830,423 - 14,836,072 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2814,829,998 - 14,836,143 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12814,376,915 - 14,382,561 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02814,416,494 - 14,421,136 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02814,548,787 - 14,554,435 (-)NCBIUU_Cfam_GSD_1.0
Fgf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721332,401,605 - 32,407,401 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366004,004,824 - 4,010,689 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049366004,004,847 - 4,010,626 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14112,808,162 - 112,814,248 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114112,808,215 - 112,814,225 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214122,661,225 - 122,666,751 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1994,797,157 - 94,803,725 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl994,798,088 - 94,803,629 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604855,874,226 - 55,880,198 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248311,253,044 - 1,257,741 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248311,251,991 - 1,259,247 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fgf8
235 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1355
Count of miRNA genes:365
Interacting mature miRNAs:405
Transcripts:ENSMUST00000026240, ENSMUST00000026241, ENSMUST00000111924, ENSMUST00000111925, ENSMUST00000111927, ENSMUST00000111928
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
14928311Manh85_mmandible shape 85 (mouse)191191478945914789Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191492301648923138Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191591260749912719Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191591260749912719Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191829516252295381Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191829516252295381Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192023431454234461Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192023431454234461Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192137870555378928Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192231332653911504Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192498843958988439Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192542691759427005Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192738559461385705Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2814034861420004Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193014122461420004Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193014123161420004Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193014123161420004Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193089788061420004Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193299215861420004Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193395195261420004Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3459678661420004Mouse
1301479Sluc1_msusceptibility to lung cancer 1 (mouse)Not determined193601694446761521Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193675259761420004Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193788298261420004Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193837605061420004Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193918406461420004Mouse
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193959606661420004Mouse
1300585Pgia12_mproteoglycan induced arthritis 12 (mouse)Not determined194258685961420004Mouse

Markers in Region
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371945,811,361 - 45,811,741UniSTSGRCm37
MGSCv371945,816,004 - 45,816,265UniSTSGRCm37
Celera1946,503,843 - 46,504,104UniSTS
Celera1946,499,200 - 46,499,580UniSTS
Cytogenetic Map19C3-DUniSTS
cM Map1945.0UniSTS
D1Bda63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381945,737,009 - 45,737,230UniSTSGRCm38
MGSCv371945,811,499 - 45,811,720UniSTSGRCm37
Celera1946,499,338 - 46,499,559UniSTS
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-DUniSTS
cM Map1945.0UniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381945,741,514 - 45,741,775UniSTSGRCm38
MGSCv371945,816,004 - 45,816,265UniSTSGRCm37
Celera1946,503,843 - 46,504,104UniSTS
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381945,736,871 - 45,737,251UniSTSGRCm38
MGSCv371945,811,361 - 45,811,741UniSTSGRCm37
Celera1946,499,200 - 46,499,580UniSTS
Cytogenetic Map19C3-DUniSTS
Fgf8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19C3-DUniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001166361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001166362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001166363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC003694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC149086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH006937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU512456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D12483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ260698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LR130364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U18673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U18746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z46883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z48746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000026240   ⟹   ENSMUSP00000026240
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1945,725,237 - 45,731,313 (-)Ensembl
GRCm38.p6 Ensembl1945,736,798 - 45,742,874 (-)Ensembl
RefSeq Acc Id: ENSMUST00000026241   ⟹   ENSMUSP00000026241
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1945,725,257 - 45,731,312 (-)Ensembl
GRCm38.p6 Ensembl1945,736,818 - 45,742,873 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111924   ⟹   ENSMUSP00000107555
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1945,725,410 - 45,731,123 (-)Ensembl
GRCm38.p6 Ensembl1945,736,971 - 45,742,684 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111925   ⟹   ENSMUSP00000107556
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1945,725,429 - 45,731,123 (-)Ensembl
GRCm38.p6 Ensembl1945,736,990 - 45,742,684 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111927   ⟹   ENSMUSP00000107558
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1945,725,375 - 45,731,297 (-)Ensembl
GRCm38.p6 Ensembl1945,736,936 - 45,742,858 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111928   ⟹   ENSMUSP00000107559
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1945,725,252 - 45,731,354 (-)Ensembl
GRCm38.p6 Ensembl1945,736,813 - 45,742,915 (-)Ensembl
RefSeq Acc Id: NM_001166361   ⟹   NP_001159833
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391945,724,930 - 45,731,333 (-)NCBI
GRCm381945,736,798 - 45,742,884 (-)NCBI
MGSCv371945,811,288 - 45,817,374 (-)RGD
Celera1946,499,127 - 46,505,223 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001166362   ⟹   NP_001159834
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391945,724,930 - 45,731,333 (-)NCBI
GRCm381945,736,798 - 45,742,884 (-)NCBI
MGSCv371945,811,288 - 45,817,374 (-)RGD
Celera1946,499,127 - 46,505,223 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001166363   ⟹   NP_001159835
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391945,724,930 - 45,731,333 (-)NCBI
GRCm381945,736,798 - 45,742,884 (-)NCBI
MGSCv371945,811,288 - 45,817,374 (-)RGD
Celera1946,499,127 - 46,505,223 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001379139   ⟹   NP_001366068
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391945,724,930 - 45,731,333 (-)NCBI
GRCm381945,736,491 - 45,742,894 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001379140   ⟹   NP_001366069
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391945,724,930 - 45,731,333 (-)NCBI
GRCm381945,736,491 - 45,742,894 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001403100   ⟹   NP_001390029
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391945,724,930 - 45,731,333 (-)NCBI
RefSeq Acc Id: NM_010205   ⟹   NP_034335
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391945,724,930 - 45,731,333 (-)NCBI
GRCm381945,736,798 - 45,742,884 (-)NCBI
MGSCv371945,811,288 - 45,817,374 (-)RGD
Celera1946,499,127 - 46,505,223 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006526668   ⟹   XP_006526731
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391945,725,237 - 45,731,380 (-)NCBI
GRCm381945,736,798 - 45,742,941 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034335   ⟸   NM_010205
- Peptide Label: isoform 1 precursor
- UniProtKB: P37237 (UniProtKB/Swiss-Prot),   Q80ZL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159833   ⟸   NM_001166361
- Peptide Label: isoform 2 precursor
- UniProtKB: Q80ZL6 (UniProtKB/TrEMBL),   A0A6P5P1R9 (UniProtKB/TrEMBL),   A0A8C6H126 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159834   ⟸   NM_001166362
- Peptide Label: isoform 3 precursor
- UniProtKB: P37237 (UniProtKB/Swiss-Prot),   Q3V279 (UniProtKB/TrEMBL),   Q80ZL6 (UniProtKB/TrEMBL),   A0A6P5P5B0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001159835   ⟸   NM_001166363
- Peptide Label: isoform 4 precursor
- UniProtKB: P37237 (UniProtKB/Swiss-Prot),   Q80ZL6 (UniProtKB/TrEMBL),   A0A6P5NZ81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006526731   ⟸   XM_006526668
- Peptide Label: isoform X2
- UniProtKB: D3Z207 (UniProtKB/TrEMBL),   A0A6P5NW92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001366069   ⟸   NM_001379140
- Peptide Label: isoform 6 precursor
RefSeq Acc Id: NP_001366068   ⟸   NM_001379139
- Peptide Label: isoform 5 precursor
RefSeq Acc Id: ENSMUSP00000107556   ⟸   ENSMUST00000111925
RefSeq Acc Id: ENSMUSP00000107558   ⟸   ENSMUST00000111927
RefSeq Acc Id: ENSMUSP00000107559   ⟸   ENSMUST00000111928
RefSeq Acc Id: ENSMUSP00000107555   ⟸   ENSMUST00000111924
RefSeq Acc Id: ENSMUSP00000026241   ⟸   ENSMUST00000026241
RefSeq Acc Id: ENSMUSP00000026240   ⟸   ENSMUST00000026240
RefSeq Acc Id: NP_001390029   ⟸   NM_001403100
- Peptide Label: isoform 7 precursor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P37237-F1-model_v2 AlphaFold P37237 1-268 view protein structure

Promoters
RGD ID:13679636
Promoter ID:EPDNEW_M23967
Type:initiation region
Name:Fgf8_1
Description:Mus musculus fibroblast growth factor 8 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381945,742,890 - 45,742,950EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99604 AgrOrtholog
Ensembl Genes ENSMUSG00000025219 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000026240 ENTREZGENE
  ENSMUSP00000026240.8 UniProtKB/TrEMBL
  ENSMUSP00000026241 ENTREZGENE
  ENSMUSP00000026241.6 UniProtKB/Swiss-Prot
  ENSMUSP00000107555.2 UniProtKB/TrEMBL
  ENSMUSP00000107556 ENTREZGENE
  ENSMUSP00000107556.2 UniProtKB/TrEMBL
  ENSMUSP00000107558 ENTREZGENE
  ENSMUSP00000107558.2 UniProtKB/Swiss-Prot
  ENSMUSP00000107559 ENTREZGENE
  ENSMUSP00000107559.2 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000026240 ENTREZGENE
  ENSMUST00000026240.14 UniProtKB/TrEMBL
  ENSMUST00000026241 ENTREZGENE
  ENSMUST00000026241.12 UniProtKB/Swiss-Prot
  ENSMUST00000111924.8 UniProtKB/TrEMBL
  ENSMUST00000111925 ENTREZGENE
  ENSMUST00000111925.2 UniProtKB/TrEMBL
  ENSMUST00000111927 ENTREZGENE
  ENSMUST00000111927.8 UniProtKB/Swiss-Prot
  ENSMUST00000111928 ENTREZGENE
  ENSMUST00000111928.8 UniProtKB/Swiss-Prot
Gene3D-CATH 2.80.10.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Fibroblast_GF_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14179 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:99604 ENTREZGENE
NCBI Gene 14179 ENTREZGENE
PANTHER PTHR11486 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11486:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fgf8 PhenoGen
PRINTS IL1HBGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A6P5NW92 ENTREZGENE
  A0A6P5NZ81 ENTREZGENE
  A0A6P5P1R9 ENTREZGENE
  A0A6P5P5B0 ENTREZGENE
  A0A8C6H126 ENTREZGENE
  D3Z207 ENTREZGENE, UniProtKB/TrEMBL
  D3Z208_MOUSE UniProtKB/TrEMBL
  FGF8_MOUSE UniProtKB/Swiss-Prot
  G3DRA7_MOUSE UniProtKB/TrEMBL
  P37237 ENTREZGENE
  Q3V279 ENTREZGENE, UniProtKB/TrEMBL
  Q60757_MOUSE UniProtKB/TrEMBL
  Q80ZL6 ENTREZGENE, UniProtKB/TrEMBL