Skp1 (S-phase kinase-associated protein 1) - Rat Genome Database

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Gene: Skp1 (S-phase kinase-associated protein 1) Mus musculus
Analyze
Symbol: Skp1
Name: S-phase kinase-associated protein 1
RGD ID: 1553334
MGI Page MGI
Description: Predicted to enable several functions, including F-box domain binding activity; beta-catenin binding activity; and cullin family protein binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within protein K48-linked ubiquitination and protein monoubiquitination. Located in centrosome and cytosol. Part of Cul7-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; notochord; and sensory organ. Orthologous to human SKP1 (S-phase kinase associated protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 15kDa; 2610043E24Rik; 2610206H23Rik; cyclin A/CDK2-associated protein p19; cyclin-A/CDK2-associated protein p19; EMC19; OCP-II; OCP2; p19A; p19S; p19Skp1; S-phase kinase-associated protein 1A; Sk; Skp1a; Tceb1; Tceb1l; transcription elongation factor B (SIII), polypeptide 1 (15 kDa),-like; transcription elongation factor B (SIII), polypeptide 1-like
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm12988  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,121,349 - 52,137,685 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1152,122,822 - 52,137,685 (+)EnsemblGRCm39 Ensembl
GRCm381152,230,522 - 52,246,858 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,231,995 - 52,246,858 (+)EnsemblGRCm38mm10GRCm38
MGSCv371152,045,497 - 52,060,360 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361152,075,432 - 52,090,281 (+)NCBIMGSCv36mm8
Celera1156,801,165 - 56,816,028 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (ISO)
calycosin  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP,ISO)
CGP 52608  (ISO)
clofibrate  (EXP)
clozapine  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dimethylarsinous acid  (ISO)
disodium selenite  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
fipronil  (ISO)
flutamide  (ISO)
folpet  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
graphite  (ISO)
indometacin  (ISO)
inulin  (EXP)
ivermectin  (ISO)
methidathion  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
nefazodone  (ISO)
nimesulide  (ISO)
Nutlin-3  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
pirinixic acid  (EXP)
piroxicam  (ISO)
sertraline  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
T-2 toxin  (ISO)
thapsigargin  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Expanding role of ubiquitination in NF-kappaB signaling. Liu S and Chen ZJ, Cell Res. 2011 Jan;21(1):6-21. Epub 2010 Dec 7.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. A novel cDNA with homology to an RNA polymerase II elongation factor maps to human chromosome 5q31 (TCEB1L) and to mouse chromosome 11 (Tceb1l). Sowden J, etal., Genomics 1995 Sep 1;29(1):145-51.
Additional References at PubMed
PMID:1707031   PMID:8912791   PMID:9021147   PMID:10097128   PMID:10349636   PMID:10485847   PMID:10531037   PMID:10585767   PMID:11042159   PMID:11076861   PMID:11337588   PMID:11735228  
PMID:11896578   PMID:12140560   PMID:12417738   PMID:12477932   PMID:12520002   PMID:12665572   PMID:12805289   PMID:12904583   PMID:14610273   PMID:14701835   PMID:15306695   PMID:15489334  
PMID:15531760   PMID:15996101   PMID:16141072   PMID:16141073   PMID:16714087   PMID:16880526   PMID:17081987   PMID:17215248   PMID:17242400   PMID:17274640   PMID:17290223   PMID:17296600  
PMID:17463251   PMID:17494702   PMID:17803915   PMID:18287559   PMID:18799693   PMID:18929646   PMID:19398581   PMID:19748892   PMID:20412781   PMID:21267068   PMID:21343341   PMID:21368834  
PMID:21572988   PMID:21873635   PMID:22033112   PMID:22166427   PMID:22205987   PMID:22306998   PMID:22354994   PMID:22405651   PMID:22673621   PMID:22988430   PMID:23314863   PMID:23375831  
PMID:23452856   PMID:23503662   PMID:23868976   PMID:23955342   PMID:24085301   PMID:24390425   PMID:24457600   PMID:25670854   PMID:26206133   PMID:26496610   PMID:27063938   PMID:27113764  
PMID:27732853   PMID:28378742   PMID:28671696   PMID:29111324   PMID:29472293   PMID:29593216   PMID:30186101   PMID:31040226   PMID:31162944   PMID:31167929   PMID:32098917   PMID:32232159  
PMID:32325033   PMID:32434143   PMID:32554809   PMID:32937135   PMID:34321999   PMID:35310947   PMID:35489071   PMID:36114006   PMID:36288084   PMID:36417873   PMID:36592647  


Genomics

Comparative Map Data
Skp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,121,349 - 52,137,685 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1152,122,822 - 52,137,685 (+)EnsemblGRCm39 Ensembl
GRCm381152,230,522 - 52,246,858 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,231,995 - 52,246,858 (+)EnsemblGRCm38mm10GRCm38
MGSCv371152,045,497 - 52,060,360 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361152,075,432 - 52,090,281 (+)NCBIMGSCv36mm8
Celera1156,801,165 - 56,816,028 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.86NCBI
SKP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385134,148,935 - 134,176,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5134,148,935 - 134,176,964 (-)EnsemblGRCh38hg38GRCh38
GRCh375133,484,626 - 133,512,641 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365133,520,468 - 133,540,583 (-)NCBINCBI36Build 36hg18NCBI36
Build 345133,520,467 - 133,540,583NCBI
Celera5129,615,775 - 129,636,409 (-)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5128,677,052 - 128,697,683 (-)NCBIHuRef
CHM1_15132,924,656 - 132,945,272 (-)NCBICHM1_1
T2T-CHM13v2.05134,672,565 - 134,700,570 (-)NCBIT2T-CHM13v2.0
Skp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81036,898,670 - 36,917,828 (+)NCBIGRCr8
mRatBN7.21036,401,987 - 36,417,066 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1036,402,153 - 36,417,388 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1041,096,029 - 41,110,942 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01040,585,994 - 40,600,907 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01036,089,722 - 36,104,635 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01037,594,578 - 37,609,498 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,594,578 - 37,609,498 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01037,368,051 - 37,383,130 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,665,417 - 37,680,338 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11037,671,846 - 37,686,768 (+)NCBI
Celera1035,756,586 - 35,771,498 (+)NCBICelera
Cytogenetic Map10q22NCBI
Skp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554085,392,839 - 5,412,644 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554085,393,851 - 5,412,644 (-)NCBIChiLan1.0ChiLan1.0
SKP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24129,455,839 - 129,478,297 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15127,595,401 - 127,617,859 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05129,560,086 - 129,580,188 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15135,713,085 - 135,732,665 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5135,713,085 - 135,729,653 (-)Ensemblpanpan1.1panPan2
SKP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,352,735 - 22,366,599 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,352,439 - 22,364,024 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1121,098,642 - 21,112,489 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01123,152,831 - 23,168,252 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1123,152,162 - 23,164,892 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11121,853,772 - 21,867,627 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01121,718,806 - 21,732,658 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,361,395 - 22,375,242 (-)NCBIUU_Cfam_GSD_1.0
Skp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213114,070,872 - 114,088,084 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366471,072,855 - 1,094,139 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366471,073,647 - 1,090,841 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SKP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2136,458,949 - 136,476,005 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12136,458,772 - 136,476,364 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SKP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12336,961,572 - 36,978,849 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2336,962,328 - 36,978,757 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603440,956,691 - 40,974,891 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Skp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473338,051,280 - 38,069,648 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Skp1
445 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:965
Count of miRNA genes:428
Interacting mature miRNAs:509
Transcripts:ENSMUST00000037324, ENSMUST00000093121, ENSMUST00000109072, ENSMUST00000116595, ENSMUST00000147684, ENSMUST00000166537
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
4141770Tcpm1_mT-cell phenotype modifier 1 (mouse)Not determined5145247953615930Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse

Markers in Region
D11Pjn4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381152,236,615 - 52,236,770UniSTSGRCm38
MGSCv371152,050,117 - 52,050,272UniSTSGRCm37
Celera1156,805,785 - 56,805,940UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map1128.02UniSTS
RH137096  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381152,246,397 - 52,246,615UniSTSGRCm38
MGSCv371152,059,899 - 52,060,117UniSTSGRCm37
Celera1156,815,567 - 56,815,785UniSTS
Cytogenetic Map11B1.3UniSTS
Skp1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
Tceb1l  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.3UniSTS
cM Map1131.0UniSTS
Tceb1l-rs1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384135,755,980 - 135,756,192UniSTSGRCm38
GRCm381152,246,046 - 52,246,255UniSTSGRCm38
MGSCv371152,059,548 - 52,059,757UniSTSGRCm37
MGSCv374135,311,895 - 135,312,107UniSTSGRCm37
Celera1156,815,216 - 56,815,425UniSTS
Celera4133,950,068 - 133,950,280UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map11B1.3UniSTS
cM Map465.5UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF083214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU841654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z47088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000037324   ⟹   ENSMUSP00000038744
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,122,836 - 52,137,685 (+)Ensembl
GRCm38.p6 Ensembl1152,232,009 - 52,246,858 (+)Ensembl
Ensembl Acc Id: ENSMUST00000093121
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,122,864 - 52,129,251 (+)Ensembl
GRCm38.p6 Ensembl1152,232,037 - 52,238,424 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109072   ⟹   ENSMUSP00000104700
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,123,016 - 52,137,685 (+)Ensembl
GRCm38.p6 Ensembl1152,232,189 - 52,246,858 (+)Ensembl
Ensembl Acc Id: ENSMUST00000116595   ⟹   ENSMUSP00000112294
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,127,691 - 52,136,879 (+)Ensembl
GRCm38.p6 Ensembl1152,236,864 - 52,246,052 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147684   ⟹   ENSMUSP00000129711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,122,822 - 52,135,921 (+)Ensembl
GRCm38.p6 Ensembl1152,231,995 - 52,245,094 (+)Ensembl
Ensembl Acc Id: ENSMUST00000166537   ⟹   ENSMUSP00000131833
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,122,864 - 52,135,924 (+)Ensembl
GRCm38.p6 Ensembl1152,232,037 - 52,245,097 (+)Ensembl
RefSeq Acc Id: NM_011543   ⟹   NP_035673
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,122,822 - 52,137,685 (+)NCBI
GRCm381152,231,995 - 52,246,858 (+)NCBI
MGSCv371152,045,497 - 52,060,360 (+)RGD
Celera1156,801,165 - 56,816,028 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532786   ⟹   XP_006532849
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,121,349 - 52,137,667 (+)NCBI
GRCm381152,230,522 - 52,246,840 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156505   ⟹   XP_036012398
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,122,581 - 52,137,667 (+)NCBI
Sequence:
RefSeq Acc Id: NP_035673   ⟸   NM_011543
- UniProtKB: Q8C5H6 (UniProtKB/Swiss-Prot),   Q9WTX5 (UniProtKB/Swiss-Prot),   Q5SUR3 (UniProtKB/TrEMBL),   Q3TL58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006532849   ⟸   XM_006532786
- Peptide Label: isoform X1
- UniProtKB: Q8C5H6 (UniProtKB/Swiss-Prot),   Q9WTX5 (UniProtKB/Swiss-Prot),   Q5SUR3 (UniProtKB/TrEMBL),   Q3TL58 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000129711   ⟸   ENSMUST00000147684
Ensembl Acc Id: ENSMUSP00000131833   ⟸   ENSMUST00000166537
Ensembl Acc Id: ENSMUSP00000038744   ⟸   ENSMUST00000037324
Ensembl Acc Id: ENSMUSP00000104700   ⟸   ENSMUST00000109072
Ensembl Acc Id: ENSMUSP00000112294   ⟸   ENSMUST00000116595
RefSeq Acc Id: XP_036012398   ⟸   XM_036156505
- Peptide Label: isoform X2
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WTX5-F1-model_v2 AlphaFold Q9WTX5 1-163 view protein structure

Promoters
RGD ID:6848602
Promoter ID:MM_TRO:1485
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney,   Liver
Transcripts:MTR000534.11.887.0
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361152,037,669 - 52,038,169 (+)MPROMDB
RGD ID:6822100
Promoter ID:MM_KWN:7339
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000109072,   NM_011543,   OTTMUST00000012514,   OTTMUST00000012515
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361152,045,111 - 52,045,611 (+)MPROMDB
RGD ID:8674578
Promoter ID:EPDNEW_M15319
Type:initiation region
Name:Skp1a_1
Description:Mus musculus S-phase kinase-associated protein 1A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15320  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381152,232,037 - 52,232,097EPDNEW
RGD ID:8674580
Promoter ID:EPDNEW_M15320
Type:initiation region
Name:Skp1a_2
Description:Mus musculus S-phase kinase-associated protein 1A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15319  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381152,232,249 - 52,232,309EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103575 AgrOrtholog
Ensembl Genes ENSMUSG00000036309 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000037324 ENTREZGENE
  ENSMUST00000037324.12 UniProtKB/Swiss-Prot
  ENSMUST00000109072.2 UniProtKB/Swiss-Prot
  ENSMUST00000116595.3 UniProtKB/TrEMBL
  ENSMUST00000147684.8 UniProtKB/TrEMBL
  ENSMUST00000166537.8 UniProtKB/TrEMBL
InterPro SKP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1-like_dim_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Skp1_comp_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Skp1_comp_POZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21402 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:103575 ENTREZGENE
NCBI Gene 21402 ENTREZGENE
PANTHER PTHR11165 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S-PHASE KINASE-ASSOCIATED PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Skp1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Skp1_POZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Skp1 PhenoGen
PIRSF E3_ubiquit_lig_SCF_Skp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Skp1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81382 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9PUV4_MOUSE UniProtKB/TrEMBL
  E9Q3Q7_MOUSE UniProtKB/TrEMBL
  F6TGP8_MOUSE UniProtKB/TrEMBL
  Q3TL58 ENTREZGENE, UniProtKB/TrEMBL
  Q5SUR3 ENTREZGENE, UniProtKB/TrEMBL
  Q8C5H6 ENTREZGENE
  Q9WTX5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8C5H6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-04-28 Skp1  S-phase kinase-associated protein 1  Skp1a  S-phase kinase-associated protein 1A  Symbol and/or name change 5135510 APPROVED