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Gene: Pkn2 (protein kinase N2) Mus musculus

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Symbol:

Pkn2

Name:

protein kinase N2

RGD ID:

1553287

MGI Page

MGI

Description:

Predicted to enable RNA polymerase binding activity; histone deacetylase binding activity; and protein serine/threonine kinase activity. Involved in apical junction assembly. Located in apical junction complex; cytoplasm; and nucleus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human PKN2 (protein kinase N2).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

6030436C20Rik; AI507382; PKN gamma; PR; Prk; PRK2; Prkcl2; protein kinase C-like 2; protein-kinase C-related kinase 2; serine/threonine kinase 7; serine/threonine-protein kinase N2; Stk; Stk7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PKN2 (protein kinase N2)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Pkn2 (protein kinase N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pkn2 (protein kinase N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PKN2 (protein kinase N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PKN2 (protein kinase N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pkn2 (protein kinase N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PKN2 (protein kinase N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PKN2 (protein kinase N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pkn2 (protein kinase N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PKN3 (protein kinase N3)	HGNC	OrthoMCL
Homo sapiens (human):	PKN1 (protein kinase N1)	HGNC	OrthoMCL
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Pkn2 (protein kinase N2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PKN2 (protein kinase N2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:153916	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid\|ZFIN)
Danio rerio (zebrafish):	pkn2 (protein kinase N2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	Pkn	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pkn-1	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pkn1	Alliance	DIOPT (OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	pkn2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	142,496,663 - 142,587,765 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	142,496,663 - 142,587,765 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	142,790,902 - 142,882,004 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	142,790,902 - 142,882,004 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	142,453,866 - 142,544,968 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	142,730,845 - 142,819,376 (-)	NCBI		MGSCv36	mm8
Celera	3	149,222,971 - 149,314,408 (-)	NCBI		Celera
Cytogenetic Map	3	H1	NCBI
cM Map	3	66.69	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(S)-nicotine (ISO)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (ISO)

2-butoxyethanol (EXP)

3,4-methylenedioxymethamphetamine (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (EXP)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

caffeine (ISO)

cisplatin (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

dexamethasone (EXP)

Dibutyl phosphate (ISO)

doxorubicin (EXP)

elemental selenium (ISO)

epoxiconazole (EXP)

fasudil (ISO)

folic acid (EXP,ISO)

FR900359 (ISO)

glafenine (ISO)

glyphosate (ISO)

ivermectin (ISO)

methyl methanesulfonate (ISO)

miconazole (EXP)

nicotine (ISO)

oxaliplatin (ISO)

paracetamol (EXP)

phenobarbital (EXP)

potassium chromate (ISO)

quercetin (ISO)

resveratrol (ISO)

selenium atom (ISO)

tamoxifen (EXP)

temozolomide (ISO)

thioacetamide (ISO)

titanium dioxide (EXP)

topotecan (ISO)

trichloroethene (ISO)

triphenyl phosphate (ISO)

triptonide (EXP)

valproic acid (ISO)

vitamin E (ISO)

Y-27632 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apical junction assembly (IDA,ISO)

apoptotic process (IEA)

cell adhesion (IEA)

cell division (IEA)

cell projection organization (IEA)

epithelial cell migration (ISO,ISS)

intracellular signal transduction (IBA)

positive regulation of cytokinesis (ISO,ISS)

positive regulation of mitotic cell cycle (ISO,ISS)

positive regulation of viral genome replication (IEA,ISO)

protein phosphorylation (ISO,ISS)

regulation of cell motility (ISO,ISS)

signal transduction (IEA)

Cellular Component

apical junction complex (IDA,ISO)

centrosome (IEA,ISO)

cleavage furrow (ISO,ISS)

cytoplasm (IDA,ISO)

cytosol (IEA,ISO)

intermediate filament cytoskeleton (IEA,ISO)

lamellipodium (ISO,ISS)

midbody (ISO,ISS)

nuclear body (IEA,ISO)

nucleoplasm (ISO)

nucleus (IDA,ISO)

perinuclear region of cytoplasm (IEA,ISO)

plasma membrane (ISO)

protein-containing complex (ISO)

Molecular Function

ATP binding (IEA)

calcium,diacylglycerol-dependent serine/threonine kinase activity (IEA)

diacylglycerol-dependent, calcium-independent serine/threonine kinase activity (IEA)

histone deacetylase binding (ISO,ISS)

kinase activity (ISO)

protein binding (IPI)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IBA,ISO,ISS)

RNA polymerase binding (IEA,ISO)

small GTPase binding (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal developmental patterning (IAGP)

abnormal embryo morphology (IAGP)

abnormal embryo turning (IAGP)

abnormal fibroblast proliferation (IAGP)

abnormal germ layer morphology (IAGP)

abnormal head development (IAGP)

abnormal mesenchyme morphology (IAGP)

abnormal mesoderm morphology (IAGP)

abnormal mitosis (IAGP)

abnormal neural crest cell migration (IAGP)

abnormal neural fold formation (IAGP)

abnormal neural tube morphology (IAGP)

abnormal rostral-caudal body axis extension (IAGP)

abnormal somite development (IAGP)

abnormal vascular development (IAGP)

abnormal vascular plexus formation (IAGP)

abnormal vitelline vasculature morphology (IAGP)

absent pharyngeal arches (IAGP)

absent vitelline blood vessels (IAGP)

cardiac hypertrophy (IAGP)

craniorachischisis (IAGP)

decreased circulating cholesterol level (IEA)

decreased circulating HDL cholesterol level (IEA)

decreased circulating total protein level (IEA)

decreased circulating unsaturated transferrin level (IEA)

decreased exploration in new environment (IEA)

decreased fibroblast proliferation (IAGP)

decreased mitotic index (IAGP)

delayed heart looping (IAGP)

disorganized yolk sac vascular plexus (IAGP)

embryonic lethality during organogenesis, complete penetrance (IAGP)

hemorrhage (IAGP)

increased circulating bilirubin level (IEA)

increased embryonic tissue cell apoptosis (IAGP)

increased startle reflex (IEA)

lethality, incomplete penetrance (IAGP)

no abnormal phenotype detected (IAGP)

open neural tube (IAGP)

overexpanded pulmonary alveolus (IAGP)

pericardial edema (IAGP)

preweaning lethality, complete penetrance (IEA)

pulmonary fibrosis (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8910519	PMID:10349636	PMID:10873767	PMID:10922068	PMID:11042159	PMID:11076861	PMID:12477932	PMID:12520002	PMID:12783890	PMID:12904583	PMID:14610273	PMID:15489334
PMID:16141072	PMID:16141073	PMID:18799693	PMID:20515922	PMID:20974804	PMID:21267068	PMID:21677750	PMID:21873635	PMID:23223530	PMID:25737280	PMID:26073538	PMID:26526197
PMID:26774483	PMID:27569559	PMID:27763641	PMID:28102564	PMID:28706196	PMID:28720584	PMID:28875501	PMID:30418981	PMID:31564129	PMID:32127582	PMID:32325033	PMID:32554809
PMID:32968282	PMID:34499618	PMID:35081338	PMID:35730579	PMID:38355793

Genomics

Comparative Map Data

Pkn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	142,496,663 - 142,587,765 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	142,496,663 - 142,587,765 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	142,790,902 - 142,882,004 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	142,790,902 - 142,882,004 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	142,453,866 - 142,544,968 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	142,730,845 - 142,819,376 (-)	NCBI		MGSCv36	mm8
Celera	3	149,222,971 - 149,314,408 (-)	NCBI		Celera
Cytogenetic Map	3	H1	NCBI
cM Map	3	66.69	NCBI

PKN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	88,684,273 - 88,836,255 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	88,684,222 - 88,836,255 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	89,149,956 - 89,301,938 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	88,922,510 - 89,074,526 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	88,862,276 - 89,011,443	NCBI
Celera	1	87,395,729 - 87,547,728 (+)	NCBI		Celera
Cytogenetic Map	1	p22.2	NCBI
HuRef	1	87,267,203 - 87,419,414 (+)	NCBI		HuRef
CHM1_1	1	89,265,019 - 89,416,992 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	88,527,688 - 88,679,643 (+)	NCBI		T2T-CHM13v2.0

Pkn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	234,454,001 - 234,559,369 (-)	NCBI		GRCr8
mRatBN7.2	2	231,793,584 - 231,898,953 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	231,793,584 - 231,898,953 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	239,572,538 - 239,677,842 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	237,466,818 - 237,572,120 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	232,330,191 - 232,435,493 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	248,735,699 - 248,840,735 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	248,735,699 - 248,840,735 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	267,265,825 - 267,370,861 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	240,903,608 - 241,009,063 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	240,892,652 - 240,944,091 (-)	NCBI
Celera	2	223,803,766 - 223,906,746 (-)	NCBI		Celera
Cytogenetic Map	2	q44	NCBI

Pkn2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	5,467,017 - 5,575,620 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955423	5,467,017 - 5,575,435 (-)	NCBI	ChiLan1.0	ChiLan1.0

PKN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	138,134,707 - 138,292,307 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	137,290,425 - 137,447,311 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	91,395,885 - 91,551,347 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	90,147,949 - 90,302,741 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	90,202,299 - 90,302,741 (+)	Ensembl	panpan1.1		panPan2

PKN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	59,556,668 - 59,638,626 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	59,559,124 - 59,709,926 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	62,264,725 - 62,394,692 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	60,067,704 - 60,197,746 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	60,067,567 - 60,220,888 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	59,633,009 - 59,762,681 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	59,588,332 - 59,718,360 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	60,074,127 - 60,204,202 (-)	NCBI		UU_Cfam_GSD_1.0

Pkn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	99,124,068 - 99,240,257 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936732	198,647 - 314,947 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936732	199,208 - 315,094 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PKN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	127,573,703 - 127,709,942 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	127,579,097 - 127,709,982 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	139,804,474 - 139,934,537 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PKN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	44,582,227 - 44,739,892 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	44,584,576 - 44,739,761 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	73,164,387 - 73,324,100 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pkn2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624742	8,742,473 - 8,865,281 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624742	8,740,102 - 8,865,483 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Pkn2
3687 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	4341
Count of miRNA genes:	941
Interacting mature miRNAs:	1357
Transcripts:	ENSMUST00000043812, ENSMUST00000166330, ENSMUST00000172521, ENSMUST00000172916, ENSMUST00000173615, ENSMUST00000173830, ENSMUST00000173913, ENSMUST00000174099, ENSMUST00000174169, ENSMUST00000174422, ENSMUST00000174680
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300753	Eae10_m	susceptibility to experimental allergic encephalomyelitis 10 (mouse)			Not determined		3	131736617	148451178	Mouse
1300752	Ap6q_m	alcohol preference 6 QTL (mouse)			Not determined		3	100372912	147045722	Mouse
1558868	Ses9_m	salmonella enteritidis susceptibility 9 (mouse)			Not determined		3	119057332	153057456	Mouse
10412120	Ccs3_m	colon cancer susceptibility 3 (mouse)			Not determined		3	131754536	146017669	Mouse
1301563	Alcp3_m	alcohol preference locus 3 (mouse)			Not determined		3	130736935	159745316	Mouse
11039523	Tbbr1_m	Trypanosoma brucei brucei response 1 (mouse)					3	130849375	159745316	Mouse
1301528	Loco1_m	locomotor activity 1 (mouse)			Not determined		3	133461893	159745316	Mouse
4142449	Tgq14_m	triglyceride QTL 14 (mouse)			Not determined			119318586	153318586	Mouse
10412240	Alpq6_m	alcohol preference QTL 6 (mouse)			Not determined		3	120772078	154772078	Mouse
4141935	Tgq15_m	triglyceride QTL 15 (mouse)			Not determined			119318586	153318586	Mouse
1301347	Fpli_m	fasting plasma insulin (mouse)			Not determined		3	126460514	159745316	Mouse
1301218	Letohc1_m	low ethanol consumption 1 (mouse)			Not determined		3	126352986	159745316	Mouse
27226733	Tibmd6_m	tibia midshaft diameter 6, 16 week (mouse)					3	101307316	149805637	Mouse
27226732	Tibmd3_m	tibia midshaft diameter 3, 10 week (mouse)					3	96607316	147805636	Mouse
1302151	Lprm2_m	lymphoproliferation modifier 2 (mouse)			Not determined		3	119778857	153779044	Mouse
1301381	Bomb1_m	bone marrow pre-B 1 (mouse)			Not determined		3	111133243	145133417	Mouse
10043919	Afpq8_m	abdominal fat percent QTL 8 (mouse)			Not determined		3	119057332	153057456	Mouse
1300619	Cdcs1_m	cytokine deficiency colitis susceptibility 1 (mouse)			Not determined		3	109834882	143835005	Mouse
1301705	Sles3_m	systemic lupus erythmatosus suppressor 3 (mouse)			Not determined		3	37174862	143353183	Mouse
4142245	Pstc1_m	periosteal circumference 1 (mouse)			Not determined		3	126270248	159745316	Mouse
1302056	Orgwq4_m	organ weight QTL 4 (mouse)			Not determined		3	30067588	147304689	Mouse
1302093	Orgwq5_m	organ weight QTL 5 (mouse)			Not determined		3	107376936	147304689	Mouse
1301100	Bdt2_m	bone density traits 2 (mouse)			Not determined		3	114736617	148736784	Mouse

Markers in Region

BB448270

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	142,792,705 - 142,792,790	UniSTS	GRCm38
MGSCv37	3	142,455,669 - 142,455,754	UniSTS	GRCm37
Celera	3	149,224,776 - 149,224,861	UniSTS
Cytogenetic Map	3	H1	UniSTS
cM Map	3	74.5	UniSTS
Whitehead/MRC_RH	3	1569.95	UniSTS

D3Mit38

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	142,830,837 - 142,830,952	UniSTS	GRCm38
MGSCv37	3	142,493,801 - 142,493,916	UniSTS	GRCm37
Celera	3	149,263,309 - 149,263,432	UniSTS
Cytogenetic Map	3	H1	UniSTS
cM Map	3	70.3	UniSTS
Whitehead Genetic	3	49.2	UniSTS
Whitehead/MRC_RH	3	1572.75	UniSTS
Whitehead_YAC	3		UniSTS

UniSTS:234838

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	142,792,054 - 142,792,296	UniSTS	GRCm38
MGSCv37	3	142,455,018 - 142,455,260	UniSTS	GRCm37
Celera	3	149,224,122 - 149,224,364	UniSTS
Cytogenetic Map	3	H1	UniSTS
cM Map	3	74.5	UniSTS

AI507382

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	142,793,848 - 142,793,963	UniSTS	GRCm38
MGSCv37	3	142,456,812 - 142,456,927	UniSTS	GRCm37
Celera	3	149,225,918 - 149,226,033	UniSTS
Cytogenetic Map	3	H1	UniSTS
cM Map	3	74.5	UniSTS
Whitehead/MRC_RH	3	1569.35	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_178654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC115865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC137970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK028469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK046248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK049713	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK054281	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK077832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK077910	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK082921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK083425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK084887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK133298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK140746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK165363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK171092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC052073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY729073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000043812 ⟹ ENSMUSP00000039566

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,496,663 - 142,587,765 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,790,902 - 142,882,004 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000166330

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,505,713 - 142,587,681 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,799,952 - 142,881,920 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000172521

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,510,550 - 142,587,751 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,804,789 - 142,881,990 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000172916

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,535,999 - 142,587,744 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,830,238 - 142,881,983 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000173615 ⟹ ENSMUSP00000133419

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,515,403 - 142,527,359 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,809,642 - 142,821,598 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000173830 ⟹ ENSMUSP00000133691

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,499,572 - 142,587,419 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,793,811 - 142,881,658 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000173913 ⟹ ENSMUSP00000134046

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,499,470 - 142,587,676 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,793,709 - 142,881,915 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000174099

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,527,070 - 142,535,019 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,821,309 - 142,829,258 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000174169

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,516,520 - 142,518,343 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,810,759 - 142,812,582 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000174422 ⟹ ENSMUSP00000134559

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,499,572 - 142,587,419 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,793,811 - 142,881,658 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000174680 ⟹ ENSMUSP00000134041

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,517,314 - 142,535,056 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,811,553 - 142,829,295 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000197529

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,558,705 - 142,561,496 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,852,944 - 142,855,735 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000200315

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	142,505,795 - 142,508,881 (-)	Ensembl
GRCm38.p6 Ensembl	3	142,800,034 - 142,803,120 (-)	Ensembl

RefSeq Acc Id:

NM_178654 ⟹ NP_848769

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	142,496,663 - 142,587,765 (-)	NCBI
GRCm38	3	142,790,902 - 142,882,004 (-)	NCBI
MGSCv37	3	142,453,866 - 142,544,968 (-)	RGD
Celera	3	149,222,971 - 149,314,408 (-)	RGD
cM Map	3		ENTREZGENE

Sequence:

show sequence

TTTTGCGACGCGGTGACAGCCAAATGGTGCGACAGGAGGAGCTGCCGCCGCGGCCGCTGCGCCC
CGCACCGAGAGCTCCGAGTCGGCTCCCGGCGTCGCCCTGAGGGAGCGGCTGAGGGAACAGAGTC
CGGCGGGCGGCGGCGGGCGGCGAGGGGAGCCGCGCCGCGAGGGCCCTCGCTCCCCGCCGCTCTC
CATGAGCCGCGCCTGCAAGCCGGGCCGCGCCTCCATGACTCCCTAGCTGCCGCTTTCTCTCCGG
TCCTCGCCCCCCGCCCGGCTCTCCCGTCCCGCCTTCTCCCTCGGCCGCGCCGCTGGGCGCCTTC
AGGTGCGGAGGCCCGAGCGGAGCGCCATGGCGTCCAACCCCGACCGGGGGGAGATCCTCCTCAC
CGAGCTGCAGGGAGATTCCCGGACTCTTCCATTTTCTGAGAATGTGAGTGCTGTTCAGAAATTA
GACTTTTCAGATACAATGGTGCAACAGAAATTGGACGACATCAAGGATCGAATAAAGAGAGAAA
TAAGGAAAGAACTGAAAATCAAAGAAGGAGCTGAAAACCTGAGGAAAGTTACAACAGATAAGAA
AAATTTGGCTTATGTAGACAACATTTTGAAAAAATCAAATAAAAAATTAGAAGAATTACATCAC
AAGCTACAAGAATTAAATGCACACATCGTTGTATCGGATCCAGAGGACTCCACAGATTGTCCGA
GGACTCCAGATACTCCAAATAGTGACTCTCGTAGTTCTACTAGCAACAATAGACTGATGGCCTT
ACAGAAACAACTGGATATAGAACTTAAAGTAAAGCAGGGTGCAGAGAACATGATACAGATGTAC
TCAAATGGCTCTTCAAAGGATCGGAAACTCCATGGTACAGCGCAGCAACTGCTACAGGATAGCA
AGACAAAAATAGAAGTCATCCGGATGCAGATTCTTCAGGCCGTCCAGACCAATGAGCTGGCTTT
TGATAATGCAAAACCTGTGATAAGCCCTCTTGAGCTTCGGATGGAAGAATTAAGACATCATTTT
AAGATAGAATTTGCAGTAGCCGAAGGTGCAAAGAATGTCATGAAGTTACTTGGCTCAGGAAAAG
TAACAGACAGAAAAGCGCTTTCAGAAGCACAAGCGAGATTTAATGAATCAAGTCAGAAGTTGGA
CCTTTTAAAGTATTCACTAGAGCAAAGGTTAAATGAGCTCCCCAGGAATCACCCCAAAAGCAGT
GTCGTCATTGAGGAGCTTTCACTGGTTGCGTCACCAACCCTGAGTCCACGGCAGAGCATGCTGT
CCACGCAGAACCAGTATAGCACACTGTCCAAGCCAGCGGCGCTAACCGGTACTTTGGAAGTTCG
TCTTATGGGGTGCCAAGATATCCTAGAGAATGTACCTGGACGGTCAAAAGCAACGTCGGTAGCA
CTACCTGGGTGGAGTCCAAGTGACAACAGATCGTCTTTTATGAGCAGAACCAGCAAGAGTAAAA
GTGGGAGTAGTCGCAACCTCCTGAAAACGGATGACTTGTCCAATGATGTTTGTGCTGTTTTGAA
GCTAGATAATACTGTGGTTGGTCAAACTAGCTGGAAACCCATTTCAAATCAGTCGTGGGACCAG
AAGTTTACACTGGAACTAGACAGGTCACGTGAACTGGAAATTTCAGTTTATTGGCGTGATTGGC
GATCTCTGTGTGCTGTAAAATTTCTGAGGTTAGAAGATTTTTTAGACAACCAGCGGCATGGCAT
GTGTCTCTATTTGGAACCACAGGGTACTTTGTTTGCAGAGGTTACTTTTTTTAATCCAGTTATT
GAAAGACGACCAAAACTCCAAAGACAAAAGAAAATTTTTTCAAAACAACAAGGCAAAACATTTC
TCAGAGCTCCTCAGATGAATATTAATATTGCCACTTGGGGAAGACTAGTGAGACGAGCTATTCC
CACAGTAAATCATTCTGGCACATTCAGCCCTCAGACTCCTGTGCCTGCAACAGTGCCAGTCGTT
GACGCACGCATTCCTGATCTAGCACCTCCGGCCAGTGACTCTACAGTAACCAAATTGGACTTTG
ATCTTGAACCTGAACCTCCTCCAGCCCCACCTCGTGCTTCTTCCCTTGGAGAGACAGATGAATC
TTCTGAATTGAGAGTTTTGGATATACCTGGACAGGGTTCAGAAACTGTTTTCAATATTGAGAAT
GACAGAAATAACCTGCGTCCAAAATCCAAATCTGAATATGAGCTGAGCATTCCTGACTCAGGTC
GAAGCTGCTGGGGTGTTGGAGAGCTTGATGACAAGAGAGCTCAGCAGAGGTTTCAGTTCAGTCT
ACAGGACTTCAGGTGCTGTGCTGTCTTGGGGAGAGGACACTTTGGAAAGGTGCTGTTGGCGGAA
TATAAACACACAAATGAAATGTTTGCAATAAAAGCCTTAAAGAAAGGAGACATTGTGGCACGAG
ATGAAGTAGACAGCCTGATGTGTGAAAAAAGAATTTTTGAGACTGTGAATAGTGTCAGGCACCC
GTTTCTAGTGAACCTTTTTGCATGTTTCCAAACAAAAGAACATGTTTGCTTCGTGATGGAGTAT
GCTGCAGGTGGTGACCTGATGATGCACATCCATACTGATGTCTTCTCTGAACCCAGAGCTGTAT
TTTATGCAGCATGTGTAGTTCTTGGGTTGCAATACTTACATGAACACAAAATTGTTTATAGAGA
TTTGAAGTTGGATAACTTGTTGCTAGATACAGAAGGCTTTGTGAAAATTGCTGACTTTGGTCTT
TGCAAAGAAGGAATGGGGTATGGAGATAGGACAAGCACATTTTGTGGTACTCCTGAGTTTCTTG
CCCCAGAAGTCCTAACAGAAACATCGTACACAAGGGCTGTAGATTGGTGGGGCCTTGGTGTACT
TATATATGAGATGCTCGTCGGCGAGTCTCCCTTTCCTGGTGATGATGAAGAAGAGGTTTTTGAC
AGTATTGTAAATGACGAAGTAAGGTATCCAAGGTTCTTATCTACAGAAGCCATTTCCATAATGA
GAAGGCTGCTAAGGAGAAATCCTGAGCGGCGCCTGGGAGCTGGTGAGAAGGATGCAGAGGATGT
CAAGAAGCACCCGTTTTTCCGGCTAACCGACTGGAGTGCTCTAATGGACAAAAAAGTAAAGCCA
CCATTTGTACCTACCATTAGAGGACGGGAAGATGTTAGTAACTTTGATGATGAATTTACCTCAG
AAGCACCTATTCTGACTCCACCTCGAGAACCAAGGATACTCTTGGAAGAGGAGCAGGAGATGTT
CCACGATTTTGACTACGTTGCTGATTGGTGTTAAGTTTCTAGACCCTGAGACCAAGCAGACTGA
CCAACAAGAAGACCTCTTGAAAACAGCAGCCCTGCATTTCCTTTCCGTGCCACCAGGAGCTTCT
GAGATTATATAAAGCACATGAAGATGTGGTTACAGTACTGTTTTATACCTTAATGTTTTCAACG
TAAATCTGAACACTGGAAGCAGTTTCATGGAGTTTAGGCTGAGTGAACATTGGCCATGGAAATC
CATTACAAATAAATACTTTTACATCAATACTCTTATTTTTAAAAAGAAGAAGAACCACTTTTTT
ATAGTCCCCATGTTTGCCCTAGGCCTGCCTTAAGTGGAAGGAAGATTAATCACTTAACTATATT
TTACAAAAGAAAAAATAGGGCTTTGGATGCTATTACTCGTAATATAAAAAGTGTGATTCTATTT
CACTAAGGCAATTATTTTTTTAAGAAATCACTATAATATGAAAAAATGTGGCAGTTTGTACACC
TTTGGTGGCTTGATTTAAAGAAAAGAATGAGAATGTATTGATGTCTATTTGATGAATTTTCTAT
ATTTATCAGGAGAACACTTTATTGCCTTAAGTTTACCAACCATGTAGCAGAGCCTCCTAGCTTT
CCAGCAGAGCTACCTGCCAAATGAGTTTGTGTATTAAACAATGCTGCAAAAAGATAGGGACATC
AGCATTCACTTAACAGTAACAATGAGGACTTCTAAGCAGCTGGAACCAAGATACCATGCTAACT
CTATGCATTCCCAAAGTCAAGGCACCGTGGAGGATGTTCAGTCAGGTCTTCCAAAGTCAGTGAA
CCTGATTAACCCTTTATTGATATGCATTCTACACGTATTTCAACCTAGACATCTTGTTCTTGTG
TCTGCTGTAGAAGGAAACTCTATCTTTGTTAAACCATAGAGATTATCATGGTATACATGCTGTG
AACATGTATATGTACAAGTTGTAATGTATTCTGTGTTGTAGGCATATTATTTAATTTCACCACG
TCATCACTTTTGTACAGTGGCCAAGCAGACACCTCCAACTCCAGCATTTCCATTAAGTGCATTT
GTACATTTTAGGCCGCTGGATCCAGATTTTATATTGGCAGTTACTGAGGGCTAAAGCAATATAT
TGTAACAGAATGTATAAATATTTTTGATAAAACAGTCTATATTTTATAAAAAGTTATTATAACA
CTAAAGCTGTACCTCAAAAGTCTCACAAATAATTTGATCAAATGCTCTACGCATCCTCAGAGGA
TCCGTTCCTGGCTTTGTATCGCTCTTACCATATGCCTGTTTGCAAATCATGATCTTCACTGGGC
TGGAATTTTATTAGATTTTTGTTTTGTTTTTCCCTTTTTTCTCCTAGGCTGTCACTCTGTTGTT
CTCCCTCAGTTCAGTAATATCAATAACTCTTTGCTTAGCATGTTAGGGCCATGATACCTCAGGA
ACAGCAGAATGGTAACAACCACACTCGAATTAACCATGTAATCACAGTGAGCTCATCTCTTACA
ATTTTCCAAATCTGCGTTATTGAGAAGCAGGAAAGTACACAAATAATGAAGAGTTGAGCTTGAA
ACAGCTTTGCTGACATACATTGGCCTGTTGTTATTGTACTCTGAGAATGATTACAATTGTCCAG
AGATTCTTTATATTACCTTCCAAATTCATTATTATTTTTCACTTAAGATCCTTTGGAAGAAAAT
TTTCTAAAAAGAGAAGCAATATGTTGCTGTAAATTGCTTTAAAATGCCAGTTAGTTGCCTTGGA
AGAGAACAATAGAAAAAAAAAAAATAGCGTAATTGTCTAGCTTTAATTGACCAGTGTTAACTCA
GTCTGAAAATAAAACACTAACTACTTTTGAGGTACAGTCTGCATACCTTTGTTGGTTCTGAAAT
ATGCATAGAAAGCAACTTTTCAAATGGGCTTTTAGCATTAAAAACTGACATAGAGTTATATACA
CAGTGTACAAAAATTTTTTTAATTGAAGTCAATCATTAAAAAATTTAGAGGTCAGGGCATAGTC
ACACAATTATGCTGAAAAAAAAAGCACTCATTTTTCTGTAGTTTAAATATATATATATATTTTA
GCCAGATTTTAAATTTTCAGAGTGTAAATAGATTTTGCTATTACTGTATGTGTATTGACTGCTC
AAGCACTTTGTAAGGAAAGTGGATACTTTAGAATGGTACCCTATGCATCCAAATGAAATGTGCC
TTTACATCATTCTAAGAAAAAGGGGGTTTTGCAGTCATAAATTACCACAAATGCACAAATTAAA
GTTTAAAATAGATTGAAATTTGTAATTTTGGTTTTAAGTTTTCATTCCTTTTAGAATTGTCCTT
GTGTTAAAATAGTTGGCTAAAAACGTTAGCTCTACTTGGAGGTCTCAAGAAAATTATTTTTAGT
TAGCTTTCTTTTCATCCTGGAGAAGGCACATTGTCCACTTTACTTGGAATAATGGGGAGATTTC
ATCTAGGTCTGTATTCTACAGCTTCTTTCATCCATGCACAGAATGGCCACTGTCACTAGACACC
AAGACCAGGAAAGTTGCCAGGAGGAGAGAAGCAATGATGTTTCCAAGACTAAAAAGCAAATATG
CTAATGTAAAGTGTAACATGGGAGCTTCCTCGTGTTAGAGCAGTGGCTCTCATCCTAGGGGGTA
TGAGAGGGGTTAGAATGGCCACTTCATAGGAGCTGCATATCAGATGCTTATATTGCAATTTATA
ATAGTAGCAAAATTACAGATATGAAGTAGCAACAAGATACCGTTAAGGTTAAGGGTCACCACAA
CATGAGGAACTGTATTAAAGGGCCGAAACATTAGGAACTTTGAGAACCACTGTGTTAGAGGGTA
ACATTTTAGTATTGGATCTAACATTTGAGAAAATTGTCTAATTAATAAAGCAGAATGCTAGCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_848769	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH52073	(Get FASTA)	NCBI Sequence Viewer
	BAC32655	(Get FASTA)	NCBI Sequence Viewer
	BAC33888	(Get FASTA)	NCBI Sequence Viewer
	BAC35716	(Get FASTA)	NCBI Sequence Viewer
	BAC37057	(Get FASTA)	NCBI Sequence Viewer
	BAC38689	(Get FASTA)	NCBI Sequence Viewer
	BAC38910	(Get FASTA)	NCBI Sequence Viewer
	BAE21599	(Get FASTA)	NCBI Sequence Viewer
	BAE42244	(Get FASTA)	NCBI Sequence Viewer
	EDL12042	(Get FASTA)	NCBI Sequence Viewer
	EDL12043	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000039566
	ENSMUSP00000039566.9
	ENSMUSP00000133419.2
	ENSMUSP00000133691.2
	ENSMUSP00000134041.2
	ENSMUSP00000134046.2
	ENSMUSP00000134559.2
GenBank Protein	Q8BWW9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_848769 ⟸ NM_178654

- UniProtKB:

Q8BWW9 (UniProtKB/Swiss-Prot), Q8BL62 (UniProtKB/Swiss-Prot), Q8BJL7 (UniProtKB/Swiss-Prot), Q80WS2 (UniProtKB/Swiss-Prot), Q3TBR3 (UniProtKB/Swiss-Prot), G3UZM9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASNPDRGEILLTELQGDSRTLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKELKIKE
GAENLRKVTTDKKNLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDSTDCPRTPDTPNSD
SRSSTSNNRLMALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKIEVIRM
QILQAVQTNELAFDNAKPVISPLELRMEELRHHFKIEFAVAEGAKNVMKLLGSGKVTDRKALSE
AQARFNESSQKLDLLKYSLEQRLNELPRNHPKSSVVIEELSLVASPTLSPRQSMLSTQNQYSTL
SKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSDNRSSFMSRTSKSKSGSSRNLLK
TDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFL
RLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNIN
IATWGRLVRRAIPTVNHSGTFSPQTPVPATVPVVDARIPDLAPPASDSTVTKLDFDLEPEPPPA
PPRASSLGETDESSELRVLDIPGQGSETVFNIENDRNNLRPKSKSEYELSIPDSGRSCWGVGEL
DDKRAQQRFQFSLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCE
KRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLG
LQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETS
YTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPE
RRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPR
EPRILLEEEQEMFHDFDYVADWC

hide sequence

Ensembl Acc Id:

ENSMUSP00000134041 ⟸ ENSMUST00000174680

Ensembl Acc Id:

ENSMUSP00000134559 ⟸ ENSMUST00000174422

Ensembl Acc Id:

ENSMUSP00000133419 ⟸ ENSMUST00000173615

Ensembl Acc Id:

ENSMUSP00000133691 ⟸ ENSMUST00000173830

Ensembl Acc Id:

ENSMUSP00000134046 ⟸ ENSMUST00000173913

Ensembl Acc Id:

ENSMUSP00000039566 ⟸ ENSMUST00000043812

Protein Domains

AGC-kinase C-terminal C2 Protein kinase Protein kinase C-terminal REM-1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8BWW9-F1-model_v2	AlphaFold	Q8BWW9	1-983	view protein structure

Promoters

RGD ID:

6833396

Promoter ID:

MM_KWN:36293

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Liver

Transcripts:

UC008RPD.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	3	142,455,671 - 142,456,171 (-)	MPROMDB

RGD ID:

6834251

Promoter ID:

MM_KWN:36294

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day4

Transcripts:

ENSMUST00000043812, ENSMUST00000090108

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	3	142,516,496 - 142,516,996 (-)	MPROMDB

RGD ID:

6833238

Promoter ID:

MM_KWN:36295

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

AK085299_9530052C20RIK, NM_178654, UC008RPF.1, UC008RPG.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	3	142,544,176 - 142,545,647 (+)	MPROMDB

RGD ID:

6882536

Promoter ID:

EPDNEW_M4719

Type:

initiation region

Name:

Pkn2_1

Description:

Mus musculus protein kinase N2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	3	142,881,955 - 142,882,015	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:109211	AgrOrtholog
Ensembl Genes	ENSMUSG00000004591	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000043812	ENTREZGENE
	ENSMUST00000043812.15	UniProtKB/Swiss-Prot
	ENSMUST00000173615.8	UniProtKB/TrEMBL
	ENSMUST00000173830.8	UniProtKB/TrEMBL
	ENSMUST00000173913.8	UniProtKB/TrEMBL
	ENSMUST00000174422.8	UniProtKB/TrEMBL
	ENSMUST00000174680.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.150	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HR1 repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	AGC-kinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C2_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C2_PKN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HR1_rho-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HR1_rpt_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PKN_HR1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser_Thr_kinase_AGC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:109333	UniProtKB/Swiss-Prot
MGD	MGI:109211	ENTREZGENE
NCBI Gene	Pkn2	ENTREZGENE
PANTHER	PROTEIN KINASE C	UniProtKB/TrEMBL
	RIBOSOMAL PROTEIN S6 KINASE	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SERINE_THREONINE-PROTEIN KINASE N2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HR1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pkn2	PhenoGen
PROSITE	AGC_KINASE_CTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PS50004	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	REM_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	Hr1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	S_TK_X	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	S_TKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00239	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF46585	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF49562	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	G3UWT9_MOUSE	UniProtKB/TrEMBL
	G3UXH4_MOUSE	UniProtKB/TrEMBL
	G3UYD6_MOUSE	UniProtKB/TrEMBL
	G3UYE1_MOUSE	UniProtKB/TrEMBL
	G3UZM9	ENTREZGENE, UniProtKB/TrEMBL
	PKN2_MOUSE	UniProtKB/Swiss-Prot
	Q3TBR3	ENTREZGENE
	Q80WS2	ENTREZGENE
	Q8BJL7	ENTREZGENE
	Q8BJM4_MOUSE	UniProtKB/TrEMBL
	Q8BL62	ENTREZGENE
	Q8BVK4_MOUSE	UniProtKB/TrEMBL
	Q8BW55_MOUSE	UniProtKB/TrEMBL
	Q8BWW9	ENTREZGENE
UniProt Secondary	Q3TBR3	UniProtKB/Swiss-Prot
	Q80WS2	UniProtKB/Swiss-Prot
	Q8BJL7	UniProtKB/Swiss-Prot
	Q8BL62	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-08-21	Pkn2	protein kinase N2	Stk7	serine/threonine kinase 7	Symbol and/or name change	5135510	APPROVED
2024-08-21	Stk7	serine/threonine kinase 7	Prkcl2	protein kinase C-like 2	Symbol and/or name change	5135510	APPROVED
2024-08-21	Prkcl2	protein kinase C-like 2	Pkn2	protein kinase N2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Mammalian Phenotype