Rdx (radixin) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Rdx (radixin) Mus musculus
Analyze
Symbol: Rdx
Name: radixin
RGD ID: 1553217
MGI Page MGI
Description: Enables protein domain specific binding activity. Involved in several processes, including cellular response to thyroid hormone stimulus; positive regulation of G1/S transition of mitotic cell cycle; and regulation of postsynaptic neurotransmitter receptor diffusion trapping. Acts upstream of or within apical protein localization and microvillus assembly. Located in several cellular components, including lamellipodium; ruffle; and stereocilium base. Colocalizes with plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Used to study Dubin-Johnson syndrome. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 24. Orthologous to human RDX (radixin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AA516625; ESP10
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39951,958,450 - 52,000,038 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl951,958,473 - 52,011,763 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38952,047,150 - 52,088,738 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl952,047,173 - 52,100,463 (+)Ensemblmm10GRCm38
MGSCv37951,855,255 - 51,896,843 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36951,800,692 - 51,841,101 (+)NCBIMGSCv36mm8
Celera949,323,161 - 49,364,735 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map928.62NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(S)-amphetamine  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Bufotalin  (ISO)
buta-1,3-diene  (EXP)
cadmium dichloride  (ISO)
cannabidiol  (EXP)
carbon nanotube  (EXP,ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
diuron  (ISO)
erianin  (EXP)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glyphosate  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
haloperidol  (ISO)
hydrazine  (EXP)
hypochlorous acid  (EXP)
isoflavones  (ISO)
ivermectin  (ISO)
lycopene  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
Methylazoxymethanol acetate  (ISO)
microcystin-LR  (ISO)
naphthalene  (EXP)
nitric oxide  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium fluoride  (EXP)
tanespimycin  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
trovafloxacin  (EXP)
tungsten  (EXP)
uranium atom  (ISO)
vinclozolin  (ISO)
Y-27632  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
adherens junction  (IBA,IEA,ISO)
apical part of cell  (IBA,IDA,IEA)
apical plasma membrane  (IEA,ISO)
cell periphery  (IEA,ISO)
cell projection  (IEA)
cell tip  (IEA,ISO)
cleavage furrow  (IEA,ISO)
cortical actin cytoskeleton  (IDA,IEA,ISO)
cytoplasm  (IEA)
cytoskeleton  (IEA)
cytosol  (TAS)
filopodium  (IBA,IDA,IEA,ISO)
focal adhesion  (IEA,ISO)
lamellipodium  (IDA,IEA,ISO)
membrane  (IEA)
microvillus  (IBA,IDA,IEA,ISO)
midbody  (IEA,ISO)
myelin sheath  (HDA)
plasma membrane  (IDA,IEA,ISO)
ruffle  (IDA)
stereocilium  (IDA,IEA)
stereocilium base  (IDA)
T-tubule  (IEA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout. Doi Y, etal., J Biol Chem 1999 Jan 22;274(4):2315-21.
2. The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation. Fazioli F, etal., Oncogene 1993 May;8(5):1335-45.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice. Liang HC, etal., Biochem Pharmacol 1997 Nov 15;54(10):1127-31.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1429901   PMID:1955455   PMID:8486357   PMID:8889548   PMID:9472040   PMID:9563848   PMID:10349636   PMID:10806479   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11812828  
PMID:12068294   PMID:12477932   PMID:12499563   PMID:12520002   PMID:12522145   PMID:12554651   PMID:12904583   PMID:14529273   PMID:14610273   PMID:14613898   PMID:15093731   PMID:15314067  
PMID:15782199   PMID:15913605   PMID:16141072   PMID:16141073   PMID:16186118   PMID:16377631   PMID:16582480   PMID:16615918   PMID:17015433   PMID:17021174   PMID:17204408   PMID:17507402  
PMID:17634366   PMID:17967808   PMID:17977945   PMID:18261459   PMID:18579745   PMID:18614175   PMID:18799693   PMID:19064715   PMID:19255442   PMID:19321616   PMID:19521500   PMID:19913059  
PMID:20109539   PMID:20660156   PMID:20706633   PMID:20830809   PMID:21047789   PMID:21160029   PMID:21267068   PMID:21289089   PMID:21343695   PMID:21451358   PMID:21659656   PMID:21677750  
PMID:21873635   PMID:21965329   PMID:22132106   PMID:22891241   PMID:23019340   PMID:23055941   PMID:23063725   PMID:23229862   PMID:23440885   PMID:23754525   PMID:24135232   PMID:24194600  
PMID:24285636   PMID:25891999   PMID:26184908   PMID:27626380   PMID:27641493   PMID:27870829   PMID:28171747   PMID:28302370   PMID:28671696   PMID:28893864   PMID:29222402   PMID:29361573  
PMID:29906485   PMID:30159668   PMID:30333137   PMID:31040226   PMID:31068622   PMID:31940751   PMID:32554809   PMID:33953177   PMID:37142655   PMID:37225424   PMID:37442135   PMID:37522872  
PMID:38355793  


Genomics

Comparative Map Data
Rdx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39951,958,450 - 52,000,038 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl951,958,473 - 52,011,763 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38952,047,150 - 52,088,738 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl952,047,173 - 52,100,463 (+)Ensemblmm10GRCm38
MGSCv37951,855,255 - 51,896,843 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36951,800,692 - 51,841,101 (+)NCBIMGSCv36mm8
Celera949,323,161 - 49,364,735 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map928.62NCBI
RDX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811110,174,922 - 110,296,614 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11109,864,295 - 110,296,712 (-)Ensemblhg38GRCh38
GRCh3711110,045,647 - 110,167,339 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611109,605,376 - 109,672,647 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3411109,605,381 - 109,655,644NCBI
Celera11107,253,634 - 107,320,905 (-)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11105,970,010 - 106,091,683 (-)NCBIHuRef
CHM1_111109,928,800 - 110,050,624 (-)NCBICHM1_1
T2T-CHM13v2.011110,184,743 - 110,306,806 (-)NCBIT2T-CHM13v2.0
Rdx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8861,275,792 - 61,348,260 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl861,274,460 - 61,333,967 (+)EnsemblGRCr8
mRatBN7.2852,379,494 - 52,437,673 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl852,379,494 - 52,437,678 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx857,928,308 - 57,971,180 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0856,207,282 - 56,250,158 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0854,071,527 - 54,114,400 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0856,570,728 - 56,612,851 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl856,585,396 - 56,610,612 (+)Ensemblrn6Rnor6.0
Rnor_5.0855,152,377 - 55,194,097 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4855,404,000 - 55,450,183 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera851,903,656 - 51,946,436 (+)NCBICelera
RGSC_v3.1855,423,053 - 55,469,236 (+)NCBI
Cytogenetic Map8q24NCBI
Rdx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541212,100,359 - 12,172,545 (-)Ensembl
ChiLan1.0NW_00495541212,100,436 - 12,184,444 (-)NCBIChiLan1.0ChiLan1.0
RDX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29110,909,905 - 111,019,235 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111112,003,902 - 112,130,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011105,075,716 - 105,176,660 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111108,921,477 - 109,005,557 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11108,921,477 - 109,005,557 (-)EnsemblpanPan2panpan1.1
RDX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1522,555,913 - 22,642,822 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl522,571,286 - 22,642,811 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha522,474,394 - 22,561,935 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0522,581,249 - 22,668,985 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl522,581,164 - 22,668,972 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1522,639,826 - 22,727,131 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0522,539,744 - 22,627,628 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0522,589,215 - 22,677,042 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rdx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494792,645,011 - 92,713,067 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366123,992,542 - 4,040,315 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366123,992,542 - 4,060,598 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RDX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl938,220,447 - 38,322,097 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1938,243,608 - 38,299,561 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2942,953,206 - 43,009,694 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RDX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11101,554,640 - 101,647,765 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1101,554,334 - 101,623,093 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604324,300,763 - 24,397,097 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rdx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247845,221,045 - 5,271,045 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247845,198,433 - 5,304,953 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Rdx
1148 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1105
Count of miRNA genes:425
Interacting mature miRNAs:477
Transcripts:ENSMUST00000000590, ENSMUST00000061352, ENSMUST00000163153
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
4141754Fecq4_mfecundity QTL 4 (mouse)Not determined94754302457805204Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
1301051Eae9_msusceptibility to experimental allergic encephalomyelitis 9 (mouse)Not determined94942029863239852Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94942029867151448Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4659767165831177Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse
13515057Adip20b_madiposity 20b (mouse)94870090853791702Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse

Markers in Region
RH124276  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38952,068,215 - 52,069,731UniSTSGRCm38
MGSCv37951,876,320 - 51,877,836UniSTSGRCm37
Celera949,344,251 - 49,345,767UniSTS
Cytogenetic Map9A5.3UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001104616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001104617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC159881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK016711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE994963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY739389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT009732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV662898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000000590   ⟹   ENSMUSP00000000590
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl951,959,415 - 52,000,029 (+)Ensembl
GRCm38.p6 Ensembl952,048,115 - 52,088,729 (+)Ensembl
Ensembl Acc Id: ENSMUST00000061352   ⟹   ENSMUSP00000055303
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl951,959,571 - 51,986,474 (+)Ensembl
GRCm38.p6 Ensembl952,048,271 - 52,075,174 (+)Ensembl
Ensembl Acc Id: ENSMUST00000163153   ⟹   ENSMUSP00000128249
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl951,958,473 - 52,000,035 (+)Ensembl
GRCm38.p6 Ensembl952,047,173 - 52,088,735 (+)Ensembl
Ensembl Acc Id: ENSMUST00000238858   ⟹   ENSMUSP00000158900
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl951,959,471 - 52,011,763 (+)Ensembl
GRCm38.p6 Ensembl952,048,171 - 52,100,463 (+)Ensembl
RefSeq Acc Id: NM_001104616   ⟹   NP_001098086
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39951,958,450 - 52,000,038 (+)NCBI
GRCm38952,047,150 - 52,088,738 (+)ENTREZGENE
MGSCv37951,855,255 - 51,896,843 (+)RGD
Celera949,323,161 - 49,364,735 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001104617   ⟹   NP_001098087
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39951,959,241 - 51,986,477 (+)NCBI
GRCm38952,047,941 - 52,075,177 (+)NCBI
MGSCv37951,855,255 - 51,896,843 (+)RGD
Celera949,323,161 - 49,364,735 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_009041   ⟹   NP_033067
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39951,959,241 - 52,000,038 (+)NCBI
GRCm38952,047,941 - 52,088,738 (+)NCBI
MGSCv37951,855,255 - 51,896,843 (+)RGD
Celera949,323,161 - 49,364,735 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033067   ⟸   NM_009041
- Peptide Label: isoform a
- UniProtKB: Q3TS85 (UniProtKB/Swiss-Prot),   Q9QW27 (UniProtKB/Swiss-Prot),   P26043 (UniProtKB/Swiss-Prot),   Q3UJJ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001098086   ⟸   NM_001104616
- Peptide Label: isoform a
- UniProtKB: Q3TS85 (UniProtKB/Swiss-Prot),   Q9QW27 (UniProtKB/Swiss-Prot),   P26043 (UniProtKB/Swiss-Prot),   Q3UJJ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001098087   ⟸   NM_001104617
- Peptide Label: isoform b
- UniProtKB: Q7TSG6 (UniProtKB/TrEMBL),   Q8C2N4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000128249   ⟸   ENSMUST00000163153
Ensembl Acc Id: ENSMUSP00000000590   ⟸   ENSMUST00000000590
Ensembl Acc Id: ENSMUSP00000158900   ⟸   ENSMUST00000238858
Ensembl Acc Id: ENSMUSP00000055303   ⟸   ENSMUST00000061352
Protein Domains
Ezrin/radixin/moesin alpha-helical   Ezrin/radixin/moesin C-terminal   FERM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P26043-F1-model_v2 AlphaFold P26043 1-583 view protein structure

Promoters
RGD ID:6845032
Promoter ID:MM_KWN:57343
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001104617,   NM_009041
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36951,855,096 - 51,856,487 (+)MPROMDB
RGD ID:8669598
Promoter ID:EPDNEW_M12830
Type:initiation region
Name:Rdx_2
Description:Mus musculus radixin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12831  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38952,048,022 - 52,048,082EPDNEW
RGD ID:8669600
Promoter ID:EPDNEW_M12831
Type:initiation region
Name:Rdx_1
Description:Mus musculus radixin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12830  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38952,048,271 - 52,048,331EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97887 AgrOrtholog
Ensembl Genes ENSMUSG00000032050 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000000590 ENTREZGENE
  ENSMUST00000000590.16 UniProtKB/Swiss-Prot
  ENSMUST00000061352 ENTREZGENE
  ENSMUST00000163153 ENTREZGENE
  ENSMUST00000163153.9 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.450 UniProtKB/Swiss-Prot
  1.20.80.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  6.10.360.10 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
InterPro Band_41_domain UniProtKB/Swiss-Prot
  ERM UniProtKB/Swiss-Prot
  ERM_C_dom UniProtKB/Swiss-Prot
  ERM_FERM_C UniProtKB/Swiss-Prot
  ERM_helical UniProtKB/Swiss-Prot
  Ez/rad/moesin-like UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_CS UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  FERM_PH-like_C UniProtKB/Swiss-Prot
  Moesin_tail_sf UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report mmu:19684 UniProtKB/Swiss-Prot
MGD MGI:97887 ENTREZGENE
NCBI Gene 19684 ENTREZGENE
PANTHER PTHR23281 UniProtKB/Swiss-Prot
Pfam ERM_C UniProtKB/Swiss-Prot
  ERM_helical UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
  FERM_M UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
PharmGKB RDX RGD
PhenoGen Rdx PhenoGen
PIRSF ERM UniProtKB/Swiss-Prot
PRINTS BAND41 UniProtKB/Swiss-Prot
  ERMFAMILY UniProtKB/Swiss-Prot
PROSITE FERM_1 UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_3 UniProtKB/Swiss-Prot
SMART B41 UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF47031 UniProtKB/Swiss-Prot
  SSF48678 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
UniProt A0A5F8MPB9 ENTREZGENE, UniProtKB/TrEMBL
  P26043 ENTREZGENE
  Q05CE6_MOUSE UniProtKB/TrEMBL
  Q3TH46_MOUSE UniProtKB/TrEMBL
  Q3TS74_MOUSE UniProtKB/TrEMBL
  Q3TS85 ENTREZGENE
  Q3U111_MOUSE UniProtKB/TrEMBL
  Q3UJJ8 ENTREZGENE, UniProtKB/TrEMBL
  Q7TSG6 ENTREZGENE, UniProtKB/TrEMBL
  Q8C2N4 ENTREZGENE, UniProtKB/TrEMBL
  Q9QW27 ENTREZGENE
  RADI_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3TS85 UniProtKB/Swiss-Prot
  Q9QW27 UniProtKB/Swiss-Prot