Ptpn6 (protein tyrosine phosphatase, non-receptor type 6) - Rat Genome Database

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Gene: Ptpn6 (protein tyrosine phosphatase, non-receptor type 6) Mus musculus
Analyze
Symbol: Ptpn6
Name: protein tyrosine phosphatase, non-receptor type 6
RGD ID: 1553000
MGI Page MGI
Description: Enables several functions, including phosphotyrosine residue binding activity; protein domain specific binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including epididymis development; negative regulation of cytokine production; and negative regulation of inflammatory response to wounding. Acts upstream of or within several processes, including hemopoiesis; negative regulation of signal transduction; and regulation of lymphocyte activation. Located in cell-cell junction. Part of alpha-beta T cell receptor complex. Is active in cytoplasm. Is expressed in several structures, including central nervous system; liver; retina; and thymus primordium. Orthologous to human PTPN6 (protein tyrosine phosphatase non-receptor type 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 70Z-SHP; hc; hcp; Hcph; hematopoietic cell protein-tyrosine phosphatase; hemopoietic cell phosphatase; me; motheaten; protein-tyrosine phosphatase 1C; Ptp; PTP-1C; Ptp1C; PTPTY-42; SH-PTP1; SH2 phosphatase 1; SHP; SHP-1; tyrosine-protein phosphatase non-receptor type 6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,697,670 - 124,715,672 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,697,670 - 124,715,677 (-)EnsemblGRCm39 Ensembl
GRCm386124,720,707 - 124,738,709 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,720,707 - 124,738,714 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,670,736 - 124,688,727 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,686,336 - 124,698,725 (-)NCBIMGSCv36mm8
Celera6126,402,447 - 126,420,442 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-diaminotoluene  (EXP)
2,6-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
anthranilic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
caffeine  (ISO)
capillarisin  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
chloroprene  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
diarsenic trioxide  (ISO)
digitoxin  (ISO)
diuron  (ISO)
elemental selenium  (ISO)
emodin  (ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
flavonoids  (ISO)
fonofos  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (EXP,ISO)
lead diacetate  (EXP)
lidocaine  (ISO)
lipopolysaccharide  (EXP)
methoxyacetic acid  (ISO)
methoxychlor  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
parathion  (ISO)
PD123319  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (EXP)
prostaglandin E2  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium stibogluconate  (ISO)
Soman  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thapsigargin  (ISO)
titanium dioxide  (EXP)
Tributyltin oxide  (EXP,ISO)
trichloroethene  (ISO)
trimethyltin  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell receptor signaling pathway  (IGI,IMP)
CD27 signaling pathway  (ISO)
cell differentiation  (IBA,ISO)
cellular response to macrophage colony-stimulating factor stimulus  (ISO)
cytokine-mediated signaling pathway  (TAS)
dephosphorylation  (IEA)
epididymis development  (IMP)
hematopoietic progenitor cell differentiation  (IMP)
intracellular signal transduction  (IBA,IDA)
MAPK cascade  (IMP)
megakaryocyte development  (IMP)
mitotic cell cycle  (IBA)
natural killer cell mediated cytotoxicity  (IMP)
negative regulation of angiogenesis  (ISO)
negative regulation of B cell receptor signaling pathway  (ISO)
negative regulation of humoral immune response mediated by circulating immunoglobulin  (IMP)
negative regulation of inflammatory response to wounding  (IDA,ISO)
negative regulation of innate immune response  (ISO)
negative regulation of interleukin-6 production  (IGI)
negative regulation of MAP kinase activity  (IMP)
negative regulation of MAPK cascade  (IMP)
negative regulation of mast cell activation involved in immune response  (IDA)
negative regulation of peptidyl-tyrosine phosphorylation  (IMP,ISO)
negative regulation of T cell proliferation  (IMP)
negative regulation of T cell receptor signaling pathway  (IMP)
negative regulation of tumor necrosis factor production  (IGI)
peptidyl-tyrosine dephosphorylation  (IBA,ISO)
peptidyl-tyrosine phosphorylation  (IMP,ISO)
platelet aggregation  (IMP)
platelet formation  (IGI)
positive regulation of cell adhesion mediated by integrin  (IMP)
positive regulation of cell population proliferation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
protein dephosphorylation  (IDA,IMP,ISO)
regulation of B cell differentiation  (IMP)
regulation of ERK1 and ERK2 cascade  (ISO)
regulation of G1/S transition of mitotic cell cycle  (ISO)
regulation of release of sequestered calcium ion into cytosol  (IGI)
response to axon injury  (ISO)
T cell activation  (ISO)
T cell proliferation  (IMP)
T cell receptor signaling pathway  (IMP)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal astrocyte morphology  (IAGP)
abnormal B cell negative selection  (IAGP)
abnormal bone marrow cell physiology  (IAGP)
abnormal CD8-positive, alpha beta T cell morphology  (IEA)
abnormal CD8-positive, alpha-beta T cell differentiation  (IEA)
abnormal cell cycle  (IAGP)
abnormal cell cycle checkpoint function  (IAGP)
abnormal circulating chemokine level  (IAGP)
abnormal CNS glial cell morphology  (IAGP)
abnormal coat appearance  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal granulocyte morphology  (IAGP)
abnormal hippocampus CA1 region morphology  (IAGP)
abnormal hippocampus development  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal immune system cell morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal immunoglobulin level  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal leukocyte cell number  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lymph organ size  (IAGP)
abnormal mature B cell morphology  (IAGP)
abnormal microglial cell morphology  (IAGP)
abnormal myelination  (IAGP)
abnormal myeloid leukocyte morphology  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal Peyer's patch morphology  (IAGP)
abnormal photoreceptor inner segment morphology  (IAGP)
abnormal photoreceptor outer segment morphology  (IAGP)
abnormal plasma cell morphology  (IAGP)
abnormal pulmonary alveolar system morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin pigmentation  (IAGP)
abnormal T cell differentiation  (IEA)
abnormal T cell physiology  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal thymus development  (IAGP)
abnormal thymus morphology  (IAGP)
absent limbs  (IAGP)
absent skin pigmentation  (IAGP)
absent tertiary ovarian follicles  (IAGP)
autoimmune response  (IAGP)
chronic inflammation  (IAGP)
decreased a-wave amplitude  (IAGP)
decreased apoptosis  (IAGP)
decreased B cell number  (IAGP)
decreased B cell proliferation  (IAGP)
decreased B-1 B cell number  (IEA)
decreased B-2 B cell number  (IEA)
decreased b-wave amplitude  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mass  (IAGP)
decreased bone mineral content  (IAGP)
decreased bone mineral density  (IAGP)
decreased brain size  (IAGP)
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number  (IEA)
decreased CD8-positive, naive alpha-beta T cell number  (IEA)
decreased cellular sensitivity to gamma-irradiation  (IAGP)
decreased follicular B cell number  (IAGP)
decreased IgD level  (IEA)
decreased IgM level  (IAGP)
decreased immature B cell number  (IEA)
decreased marginal zone B cell number  (IAGP)
decreased mature B cell number  (IAGP)
decreased neuron number  (IAGP)
decreased retina photoreceptor cell number  (IAGP)
decreased susceptibility to bacterial infection  (IAGP)
decreased susceptibility to bacterial infection induced morbidity/mortality  (IAGP)
decreased thymocyte number  (IAGP)
disorganized photoreceptor outer segment  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
extremity edema  (IAGP)
female infertility  (IAGP)
focal hair loss  (IAGP)
increased anti-chromatin antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased B cell number  (IAGP)
increased B-1 B cell number  (IEA)
increased B-1a cell number  (IAGP)
increased B-1b cell number  (IEA)
increased CD8-positive, alpha-beta memory T cell number  (IEA)
increased central memory CD8 positive, alpha-beta T cell number  (IEA)
increased circulating interferon-gamma level  (IAGP)
increased circulating interleukin-1 beta level  (IAGP)
increased circulating interleukin-10 level  (IAGP)
increased circulating interleukin-17 level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased circulating serum amyloid protein level  (IAGP)
increased dendritic cell number  (IEA)
increased effector memory CD4-positive, alpha-beta T cell number  (IEA)
increased effector memory CD8-positive, alpha-beta T cell number  (IEA)
increased erythroid progenitor cell number  (IAGP)
increased granulocyte number  (IAGP)
increased IgA level  (IAGP)
increased IgG level  (IAGP)
increased IgM level  (IAGP)
increased immunoglobulin level  (IAGP)
increased inflammatory response  (IEA)
increased leukocyte cell number  (IAGP)
increased macrophage cell number  (IAGP)
increased microglial cell activation  (IAGP)
increased monocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased plasma cell number  (IAGP)
increased splenocyte proliferation  (IAGP)
increased susceptibility to systemic lupus erythematosus  (IAGP)
increased T cell number  (IAGP)
interstitial pneumonia  (IAGP)
lung inflammation  (IAGP)
ovary atrophy  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
psoriasis  (IAGP)
respiratory distress  (IAGP)
retina outer nuclear layer degeneration  (IAGP)
retina photoreceptor degeneration  (IAGP)
retina rod cell degeneration  (IAGP)
rheumatoid arthritis  (IAGP)
salivary gland inflammation  (IAGP)
short photoreceptor outer segment  (IAGP)
skin inflammation  (IAGP)
skin lesions  (IAGP)
small thymus  (IAGP)
spontaneous skin ulceration  (IAGP)
thin retina outer nuclear layer  (IAGP)
thymus atrophy  (IAGP)
ulcerated autopod  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. AT2 receptors: functional relevance in cardiovascular disease. Jones ES, etal., Pharmacol Ther. 2008 Dec;120(3):292-316. Epub 2008 Aug 31.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Mouse chromosomal location of three epithelial sodium channel subunit genes and an apical sodium chloride cotransporter gene. Pathak BG, etal., Genomics 1996 Apr 1;33(1):124-7.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Significance of SHP-1 and SHP-2 expression in human papillomavirus infected Condyloma acuminatum and cervical cancer. Tao XH, etal., Pathol Oncol Res. 2008 Dec;14(4):365-71. doi: 10.1007/s12253-008-9065-5. Epub 2008 Jun 10.
10. JAK/STAT signal transduction: regulators and implication in hematological malignancies. Valentino L and Pierre J, Biochem Pharmacol. 2006 Mar 14;71(6):713-21. Epub 2006 Jan 19.
Additional References at PubMed
PMID:56406   PMID:221571   PMID:363947   PMID:664185   PMID:1184950   PMID:1270804   PMID:1373816   PMID:1385421   PMID:1427910   PMID:1732748   PMID:1756226   PMID:1932742  
PMID:2196000   PMID:2783574   PMID:2884254   PMID:3551623   PMID:3873348   PMID:3891855   PMID:6334306   PMID:6350031   PMID:6361123   PMID:6380298   PMID:6971254   PMID:7536621  
PMID:7600299   PMID:7768898   PMID:7804149   PMID:7840851   PMID:7923924   PMID:7943179   PMID:8070815   PMID:8093859   PMID:8118868   PMID:8245788   PMID:8324828   PMID:8348149  
PMID:8632004   PMID:8636158   PMID:8666788   PMID:8673130   PMID:8781712   PMID:8822276   PMID:8863726   PMID:8875997   PMID:8943354   PMID:8962111   PMID:9034146   PMID:9047385  
PMID:9064328   PMID:9064344   PMID:9070220   PMID:9111009   PMID:9184911   PMID:9216734   PMID:9254656   PMID:9263478   PMID:9300728   PMID:9358756   PMID:9371744   PMID:9422771  
PMID:9445485   PMID:9505936   PMID:9573011   PMID:9586639   PMID:9587708   PMID:9593582   PMID:9636682   PMID:9712903   PMID:9740804   PMID:9808051   PMID:9824165   PMID:9867848  
PMID:9890995   PMID:9973385   PMID:10026201   PMID:10201897   PMID:10229823   PMID:10229828   PMID:10330148   PMID:10349636   PMID:10352248   PMID:10358768   PMID:10363996   PMID:10393854  
PMID:10419485   PMID:10435725   PMID:10477552   PMID:10477564   PMID:10495129   PMID:10556798   PMID:10585470   PMID:10590266   PMID:10611342   PMID:10698306   PMID:10903732   PMID:10922068  
PMID:11042159   PMID:11067945   PMID:11076861   PMID:11145649   PMID:11157073   PMID:11159516   PMID:11217851   PMID:11266449   PMID:11283158   PMID:11389549   PMID:11551923   PMID:11668176  
PMID:11745335   PMID:11745639   PMID:11826756   PMID:11908943   PMID:11908944   PMID:11970996   PMID:12097380   PMID:12176909   PMID:12220225   PMID:12466851   PMID:12477932   PMID:12511594  
PMID:12612075   PMID:12644021   PMID:12645942   PMID:12646217   PMID:12742656   PMID:12893283   PMID:14500659   PMID:14662855   PMID:14967925   PMID:14987753   PMID:14988381   PMID:15197735  
PMID:15240733   PMID:15339845   PMID:15364920   PMID:15456853   PMID:15489334   PMID:15634925   PMID:15661890   PMID:15701718   PMID:15723811   PMID:15728495   PMID:15905501   PMID:16141072  
PMID:16141073   PMID:16237056   PMID:16265671   PMID:16326706   PMID:16487932   PMID:16492738   PMID:16505059   PMID:16528752   PMID:16565987   PMID:16569683   PMID:16617349   PMID:16702225  
PMID:16731527   PMID:16731906   PMID:16782884   PMID:16860389   PMID:17003515   PMID:17057094   PMID:17182570   PMID:17239631   PMID:17600736   PMID:17934470   PMID:17954568   PMID:18003716  
PMID:18024433   PMID:18028878   PMID:18258420   PMID:18391954   PMID:18424711   PMID:18441283   PMID:18617527   PMID:18719282   PMID:18799693   PMID:18806225   PMID:18832698   PMID:18952289  
PMID:18952567   PMID:18981103   PMID:18987138   PMID:19120489   PMID:19171907   PMID:19201834   PMID:19380785   PMID:19419305   PMID:19647226   PMID:19727691   PMID:19789387   PMID:19875169  
PMID:19948503   PMID:19951174   PMID:20042576   PMID:20117097   PMID:20145200   PMID:20190757   PMID:20368344   PMID:20400923   PMID:20421975   PMID:20526344   PMID:20696858   PMID:20858858  
PMID:20952680   PMID:21029969   PMID:21044800   PMID:21160041   PMID:21267068   PMID:21356343   PMID:21357539   PMID:21364532   PMID:21376641   PMID:21422245   PMID:21423172   PMID:21435452  
PMID:21559430   PMID:21664461   PMID:21677750   PMID:21683628   PMID:21873635   PMID:21900501   PMID:21952243   PMID:22077594   PMID:22337713   PMID:22415018   PMID:22438258   PMID:22491248  
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PMID:22952938   PMID:23001144   PMID:23112346   PMID:23341629   PMID:23390550   PMID:23427253   PMID:23479228   PMID:23509158   PMID:23509253   PMID:23521885   PMID:23531619   PMID:23640895  
PMID:23708968   PMID:23766558   PMID:23793062   PMID:23797092   PMID:23840825   PMID:23896411   PMID:23904162   PMID:24029230   PMID:24327268   PMID:24360797   PMID:24466030   PMID:24590766  
PMID:24819344   PMID:24824657   PMID:24841652   PMID:24899508   PMID:24978161   PMID:24990897   PMID:25057927   PMID:25090641   PMID:25187664   PMID:25355530   PMID:25404734   PMID:25681345  
PMID:25769611   PMID:25881561   PMID:25915125   PMID:25919645   PMID:26002917   PMID:26101325   PMID:26416283   PMID:26669445   PMID:26878112   PMID:27020408   PMID:27091932   PMID:27114609  
PMID:27221212   PMID:27354309   PMID:27396328   PMID:27548433   PMID:27614023   PMID:27670070   PMID:27742545   PMID:27830702   PMID:27841348   PMID:27926878   PMID:27930667   PMID:27933336  
PMID:28250424   PMID:28378742   PMID:28389241   PMID:28410990   PMID:28465325   PMID:28533521   PMID:28550200   PMID:28875936   PMID:29074590   PMID:29085371   PMID:29113698   PMID:29629899  
PMID:29669741   PMID:29776962   PMID:29891536   PMID:30033153   PMID:30082320   PMID:30333137   PMID:30413615   PMID:30429161   PMID:30796181   PMID:30823936   PMID:30929511   PMID:30961932  
PMID:30979083   PMID:31076529   PMID:31204070   PMID:31591574   PMID:31597758   PMID:31819256   PMID:31932808   PMID:32004441   PMID:32075800   PMID:32092146   PMID:32203187   PMID:32290105  
PMID:32325033   PMID:32343611   PMID:32437509   PMID:32441214   PMID:32554809   PMID:32586377   PMID:32619269   PMID:32779804   PMID:32960817   PMID:33133093   PMID:33532715   PMID:33568397  
PMID:33589816   PMID:33751937   PMID:34320834   PMID:34321999   PMID:34362877   PMID:35307366   PMID:36194675   PMID:36412197   PMID:36608128   PMID:36725700   PMID:37006301   PMID:37040441  
PMID:37067793   PMID:37507049   PMID:37595871   PMID:38599809  


Genomics

Comparative Map Data
Ptpn6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,697,670 - 124,715,672 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,697,670 - 124,715,677 (-)EnsemblGRCm39 Ensembl
GRCm386124,720,707 - 124,738,709 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,720,707 - 124,738,714 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,670,736 - 124,688,727 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,686,336 - 124,698,725 (-)NCBIMGSCv36mm8
Celera6126,402,447 - 126,420,442 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
PTPN6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,946,577 - 6,961,316 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,946,468 - 6,961,316 (+)EnsemblGRCh38hg38GRCh38
GRCh37127,055,740 - 7,070,479 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,926,001 - 6,940,740 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,930,762 - 6,940,740NCBI
Celera128,674,361 - 8,691,497 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,911,844 - 6,928,943 (+)NCBIHuRef
CHM1_1127,054,727 - 7,069,431 (+)NCBICHM1_1
T2T-CHM13v2.0126,957,743 - 6,974,790 (+)NCBIT2T-CHM13v2.0
Ptpn6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,212,320 - 159,237,069 (-)NCBIGRCr8
mRatBN7.24157,526,034 - 157,550,783 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,526,035 - 157,550,984 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,754,524 - 163,773,000 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,537,429 - 159,555,906 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,178,993 - 158,197,490 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,239,141 - 157,263,890 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,239,142 - 157,263,890 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,256,737 - 224,281,486 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,843,699 - 160,868,856 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14161,088,634 - 161,113,792 (-)NCBI
Celera4146,264,696 - 146,289,049 (-)NCBICelera
Cytogenetic Map4q42NCBI
Ptpn6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,525,954 - 4,547,177 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,525,954 - 4,547,177 (+)NCBIChiLan1.0ChiLan1.0
PTPN6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,510,113 - 12,527,309 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,506,872 - 12,524,068 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,075,879 - 7,093,041 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,991,099 - 7,008,830 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,991,099 - 7,008,830 (+)Ensemblpanpan1.1panPan2
PTPN6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,084,976 - 38,101,552 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,084,980 - 38,101,937 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,519,708 - 8,531,714 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,437,567 - 38,449,584 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,437,569 - 38,453,615 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,312,457 - 38,324,047 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,353,429 - 38,365,020 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,998,465 - 8,010,486 (+)NCBIUU_Cfam_GSD_1.0
Ptpn6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,196,659 - 102,217,158 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709864,197 - 884,610 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936709864,206 - 884,630 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,762,112 - 63,808,350 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,762,109 - 63,779,086 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,198,250 - 66,215,843 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,977,480 - 6,994,525 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,984,710 - 6,994,545 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,223,213 - 1,240,430 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptpn6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,580,560 - 3,595,090 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,580,225 - 3,595,403 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptpn6
441 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3058
Count of miRNA genes:768
Interacting mature miRNAs:1019
Transcripts:ENSMUST00000004377, ENSMUST00000112484, ENSMUST00000171549, ENSMUST00000172613, ENSMUST00000172690, ENSMUST00000172770, ENSMUST00000173228, ENSMUST00000173315, ENSMUST00000173647, ENSMUST00000174265, ENSMUST00000174787
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104480321127019938Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
10043891Tilss4_mTNF-induced lethal shock susceptibility 3 (mouse)Not determined6112246918125333748Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690772571124772807Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141064Ath37_matherosclerosis 37 (mouse)Not determined6116641858128495988Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse

Markers in Region
M68902  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386124,720,717 - 124,720,887UniSTSGRCm38
MGSCv376124,670,735 - 124,670,905UniSTSGRCm37
Celera6126,402,446 - 126,402,616UniSTS
Cytogenetic Map6F2UniSTS
cM Map660.22UniSTS
Whitehead_YAC6 UniSTS
AI411273  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386124,721,149 - 124,721,653UniSTSGRCm38
MGSCv376124,671,167 - 124,671,671UniSTSGRCm37
Celera6126,402,878 - 126,403,382UniSTS
Cytogenetic Map6F2UniSTS
cM Map660.22UniSTS
Hcph  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386124,720,790 - 124,721,198UniSTSGRCm38
MGSCv376124,670,808 - 124,671,216UniSTSGRCm37
Celera6126,402,519 - 126,402,927UniSTS
Cytogenetic Map6F2UniSTS
cM Map660.22UniSTS
Ptpn6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6F2UniSTS
cM Map660.22UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001077705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC002397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC164157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY035180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY747031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M68902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M90389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S63763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S63764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S63803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000004377   ⟹   ENSMUSP00000004377
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,697,670 - 124,715,588 (-)Ensembl
GRCm38.p6 Ensembl6124,720,707 - 124,738,625 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112484   ⟹   ENSMUSP00000108103
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,697,670 - 124,710,117 (-)Ensembl
GRCm38.p6 Ensembl6124,720,707 - 124,733,154 (-)Ensembl
Ensembl Acc Id: ENSMUST00000171549   ⟹   ENSMUSP00000129124
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,697,670 - 124,715,677 (-)Ensembl
GRCm38.p6 Ensembl6124,720,707 - 124,738,714 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172613
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,704,710 - 124,705,671 (-)Ensembl
GRCm38.p6 Ensembl6124,727,747 - 124,728,708 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172690   ⟹   ENSMUSP00000134638
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,702,250 - 124,704,424 (-)Ensembl
GRCm38.p6 Ensembl6124,725,287 - 124,727,461 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172770
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,709,618 - 124,710,073 (-)Ensembl
GRCm38.p6 Ensembl6124,732,655 - 124,733,110 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173228
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,705,864 - 124,709,734 (-)Ensembl
GRCm38.p6 Ensembl6124,728,901 - 124,732,771 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173315   ⟹   ENSMUSP00000134274
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,697,683 - 124,698,805 (-)Ensembl
GRCm38.p6 Ensembl6124,720,720 - 124,721,842 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173647   ⟹   ENSMUSP00000133747
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,709,325 - 124,710,045 (-)Ensembl
GRCm38.p6 Ensembl6124,732,362 - 124,733,082 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174265   ⟹   ENSMUSP00000133991
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,698,071 - 124,715,547 (-)Ensembl
GRCm38.p6 Ensembl6124,721,108 - 124,738,584 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174787   ⟹   ENSMUSP00000133429
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,702,298 - 124,704,374 (-)Ensembl
GRCm38.p6 Ensembl6124,725,335 - 124,727,411 (-)Ensembl
RefSeq Acc Id: NM_001077705   ⟹   NP_001071173
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,697,670 - 124,715,672 (-)NCBI
GRCm386124,720,707 - 124,738,709 (-)NCBI
MGSCv376124,670,736 - 124,688,727 (-)RGD
Celera6126,402,436 - 126,420,442 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_013545   ⟹   NP_038573
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,697,670 - 124,710,117 (-)NCBI
GRCm386124,720,707 - 124,733,154 (-)NCBI
MGSCv376124,670,736 - 124,688,727 (-)RGD
Celera6126,402,436 - 126,420,442 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_001071173   ⟸   NM_001077705
- Peptide Label: isoform b
- UniProtKB: Q3UB72 (UniProtKB/TrEMBL),   Q3UCJ0 (UniProtKB/TrEMBL),   Q3TE70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_038573   ⟸   NM_013545
- Peptide Label: isoform a
- UniProtKB: Q9QVA8 (UniProtKB/Swiss-Prot),   Q9QVA7 (UniProtKB/Swiss-Prot),   Q9QVA6 (UniProtKB/Swiss-Prot),   Q921G3 (UniProtKB/Swiss-Prot),   Q63874 (UniProtKB/Swiss-Prot),   Q63873 (UniProtKB/Swiss-Prot),   Q63872 (UniProtKB/Swiss-Prot),   O35128 (UniProtKB/Swiss-Prot),   Q9R0V6 (UniProtKB/Swiss-Prot),   P29351 (UniProtKB/Swiss-Prot),   Q3UB72 (UniProtKB/TrEMBL),   Q3TE70 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000134638   ⟸   ENSMUST00000172690
Ensembl Acc Id: ENSMUSP00000108103   ⟸   ENSMUST00000112484
Ensembl Acc Id: ENSMUSP00000129124   ⟸   ENSMUST00000171549
Ensembl Acc Id: ENSMUSP00000133429   ⟸   ENSMUST00000174787
Ensembl Acc Id: ENSMUSP00000133991   ⟸   ENSMUST00000174265
Ensembl Acc Id: ENSMUSP00000134274   ⟸   ENSMUST00000173315
Ensembl Acc Id: ENSMUSP00000133747   ⟸   ENSMUST00000173647
Ensembl Acc Id: ENSMUSP00000004377   ⟸   ENSMUST00000004377
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P29351-F1-model_v2 AlphaFold P29351 1-595 view protein structure

Promoters
RGD ID:6848843
Promoter ID:MM_TRO:8522
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   Spleen
Transcripts:MTR006068.6.2338.3
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,670,881 - 124,671,487 (-)MPROMDB
RGD ID:6848024
Promoter ID:MM_ACW:42701
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   Spleen
Transcripts:PTPN6.DSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,678,311 - 124,678,811 (-)MPROMDB
RGD ID:6839805
Promoter ID:MM_KWN:47558
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000004377,   ENSMUST00000112484
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,682,854 - 124,683,354 (-)MPROMDB
RGD ID:6839806
Promoter ID:MM_KWN:47559
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:NM_001077705,   UC009DRJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,688,691 - 124,689,442 (-)MPROMDB
RGD ID:6890976
Promoter ID:EPDNEW_M8939
Type:initiation region
Name:Ptpn6_1
Description:Mus musculus protein tyrosine phosphatase, non-receptor type6 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8940  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386124,733,110 - 124,733,170EPDNEW
RGD ID:6890978
Promoter ID:EPDNEW_M8940
Type:initiation region
Name:Ptpn6_2
Description:Mus musculus protein tyrosine phosphatase, non-receptor type6 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8939  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386124,738,661 - 124,738,721EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96055 AgrOrtholog
Ensembl Genes ENSMUSG00000004266 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000004377.15 UniProtKB/Swiss-Prot
  ENSMUST00000112484 ENTREZGENE
  ENSMUST00000112484.10 UniProtKB/Swiss-Prot
  ENSMUST00000171549 ENTREZGENE
  ENSMUST00000171549.9 UniProtKB/Swiss-Prot
  ENSMUST00000172690.2 UniProtKB/TrEMBL
  ENSMUST00000173315.8 UniProtKB/TrEMBL
  ENSMUST00000173647.2 UniProtKB/TrEMBL
  ENSMUST00000174265.2 UniProtKB/Swiss-Prot
  ENSMUST00000174787.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Non-rcpt_Tyr_Phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPase_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_non-rcpt_typ-6/11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96055 ENTREZGENE
NCBI Gene 15170 ENTREZGENE
PANTHER TYROSINE-PROTEIN PHOSPHATASE CORKSCREW UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PTPN6 RGD
PhenoGen Ptpn6 PhenoGen
PIRSF Tyr-Ptase_nr_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3UWU7_MOUSE UniProtKB/TrEMBL
  G3UXM2_MOUSE UniProtKB/TrEMBL
  G3UYY5_MOUSE UniProtKB/TrEMBL
  G3UZU6_MOUSE UniProtKB/TrEMBL
  O35128 ENTREZGENE
  P29351 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3TE70 ENTREZGENE, UniProtKB/TrEMBL
  Q3UB72 ENTREZGENE, UniProtKB/TrEMBL
  Q3UCJ0 ENTREZGENE, UniProtKB/TrEMBL
  Q63872 ENTREZGENE
  Q63873 ENTREZGENE
  Q63874 ENTREZGENE
  Q921G3 ENTREZGENE
  Q9QVA6 ENTREZGENE
  Q9QVA7 ENTREZGENE
  Q9QVA8 ENTREZGENE
  Q9R0V6 ENTREZGENE
UniProt Secondary O35128 UniProtKB/Swiss-Prot
  Q63872 UniProtKB/Swiss-Prot
  Q63873 UniProtKB/Swiss-Prot
  Q63874 UniProtKB/Swiss-Prot
  Q921G3 UniProtKB/Swiss-Prot
  Q9QVA6 UniProtKB/Swiss-Prot
  Q9QVA7 UniProtKB/Swiss-Prot
  Q9QVA8 UniProtKB/Swiss-Prot
  Q9R0V6 UniProtKB/Swiss-Prot