Cct2 (chaperonin containing TCP1 subunit 2) - Rat Genome Database

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Gene: Cct2 (chaperonin containing TCP1 subunit 2) Mus musculus
Analyze
Symbol: Cct2
Name: chaperonin containing TCP1 subunit 2
RGD ID: 1552962
MGI Page MGI
Description: Predicted to enable protein folding chaperone; ubiquitin protein ligase binding activity; and unfolded protein binding activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in cell body. Part of chaperonin-containing T-complex and zona pellucida receptor complex. Is expressed in central nervous system; nasal process; and somite. Used to study Leber congenital amaurosis. Orthologous to human CCT2 (chaperonin containing TCP1 subunit 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CCT-beta; Cctb; chaperonin containing Tcp1, subunit 2 (beta); chaperonin subunit 2 (beta); T-complex protein 1 subunit beta; TCP-1-beta
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910116,886,902 - 116,899,757 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10116,886,906 - 116,899,719 (-)EnsemblGRCm39 Ensembl
GRCm3810117,050,997 - 117,063,852 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10117,051,001 - 117,063,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710116,488,054 - 116,500,870 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610116,455,109 - 116,467,875 (-)NCBIMGSCv36mm8
Celera10118,994,151 - 119,006,966 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1065.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
1H-pyrazole  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-amino-2,6-dinitrotoluene  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
ceruletide  (ISO)
chlorophyllin  (ISO)
chloropicrin  (ISO)
chromium(6+)  (EXP)
clobetasol  (EXP)
clofibrate  (EXP)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (ISO)
hyaluronic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (EXP,ISO)
ivermectin  (ISO)
lead(II) chloride  (ISO)
menadione  (ISO)
methamphetamine  (ISO)
methidathion  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (ISO)
naphthalene  (EXP)
nefazodone  (ISO)
nickel dichloride  (ISO)
nimesulide  (ISO)
oxaliplatin  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
PhIP  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
sulforaphane  (EXP,ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
zearalenone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations. Easterday MC, etal., Dev Biol 2003 Dec 15;264(2):309-22.
2. Characterization of genes modulated during pheomelanogenesis using differential display. Furumura M, etal., Proc Natl Acad Sci U S A 1998 Jun 23;95(13):7374-8.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Kubota H, etal., Curr Biol 1994 Feb 1;4(2):89-99.
5. The chaperonin containing t-complex polypeptide 1 (TCP-1). Multisubunit machinery assisting in protein folding and assembly in the eukaryotic cytosol. Kubota H, etal., Eur J Biochem 1995 May 15;230(1):3-16.
6. Structures and co-regulated expression of the genes encoding mouse cytosolic chaperonin CCT subunits. Kubota H, etal., Eur J Biochem 1999 Jun;262(2):492-500.
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. O'Bryan JP, etal., Mol Cell Biol 1991 Oct;11(10):5016-31.
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7828721   PMID:9250675   PMID:10349636   PMID:10748209   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334  
PMID:15782199   PMID:16107646   PMID:16141072   PMID:16141073   PMID:17309103   PMID:17634366   PMID:18448421   PMID:18799693   PMID:19423573   PMID:20360068   PMID:21267068   PMID:21873635  
PMID:21880732   PMID:22083510   PMID:22144988   PMID:22673621   PMID:22794259   PMID:23665500   PMID:23716698   PMID:24457600   PMID:24788519   PMID:26496610   PMID:26584622   PMID:27889896  
PMID:28378742   PMID:30068389   PMID:30333137   PMID:30457570   PMID:30550785   PMID:30562941   PMID:30595499   PMID:30713523   PMID:32325033   PMID:32554809   PMID:34321999   PMID:35366418  
PMID:35449600   PMID:36114006   PMID:36293380   PMID:36792666   PMID:37142655   PMID:37442135   PMID:38830954  


Genomics

Comparative Map Data
Cct2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910116,886,902 - 116,899,757 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10116,886,906 - 116,899,719 (-)EnsemblGRCm39 Ensembl
GRCm3810117,050,997 - 117,063,852 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10117,051,001 - 117,063,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710116,488,054 - 116,500,870 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610116,455,109 - 116,467,875 (-)NCBIMGSCv36mm8
Celera10118,994,151 - 119,006,966 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1065.07NCBI
CCT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381269,585,459 - 69,601,570 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1269,585,426 - 69,601,570 (+)EnsemblGRCh38hg38GRCh38
GRCh371269,979,239 - 69,995,350 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361268,265,475 - 68,281,624 (+)NCBINCBI36Build 36hg18NCBI36
Build 341268,265,474 - 68,281,624NCBI
Celera1269,642,857 - 69,659,010 (+)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1267,028,675 - 67,044,820 (+)NCBIHuRef
CHM1_11269,947,631 - 69,963,780 (+)NCBICHM1_1
T2T-CHM13v2.01269,564,374 - 69,580,485 (+)NCBIT2T-CHM13v2.0
Cct2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8754,578,654 - 54,591,428 (-)NCBIGRCr8
mRatBN7.2752,692,725 - 52,705,478 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl752,692,725 - 52,706,944 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx754,599,478 - 54,612,221 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0756,802,584 - 56,815,327 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0756,580,484 - 56,593,227 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0760,106,532 - 60,122,779 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl760,109,974 - 60,122,805 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0760,106,598 - 60,122,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4756,391,341 - 56,404,084 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1756,412,071 - 56,424,814 (-)NCBI
Celera749,468,323 - 49,481,066 (-)NCBICelera
Cytogenetic Map7q22NCBI
Cct2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554059,892,116 - 9,904,407 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554059,892,089 - 9,904,407 (+)NCBIChiLan1.0ChiLan1.0
CCT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21077,617,597 - 77,633,554 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11277,613,995 - 77,629,952 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01267,113,221 - 67,128,159 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11269,883,710 - 69,898,671 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1269,883,710 - 69,898,671 (+)Ensemblpanpan1.1panPan2
CCT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11011,560,287 - 11,586,559 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1011,560,396 - 11,578,433 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1011,492,095 - 11,518,353 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01011,683,661 - 11,709,923 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1011,683,710 - 11,701,919 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11011,550,671 - 11,576,938 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01011,797,739 - 11,824,127 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01011,920,916 - 11,939,358 (+)NCBIUU_Cfam_GSD_1.0
Cct2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494546,673,102 - 46,693,918 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365457,415,753 - 7,439,800 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365457,416,257 - 7,436,024 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl533,858,572 - 33,873,523 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1533,858,514 - 33,873,596 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2536,457,610 - 36,471,587 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11165,213,992 - 65,230,318 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1165,214,060 - 65,230,379 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037180,459,300 - 180,475,791 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cct2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475028,198,475 - 28,217,158 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475028,202,524 - 28,217,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cct2
475 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:74
Interacting mature miRNAs:74
Transcripts:ENSMUST00000047672
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301520Uvbi1_mUVB induced immunosuppression 1 (mouse)Not determined1086909085120909229Mouse
26884377Skwq3_mskull length QTL 3, 5 week (mouse)10114635905122735905Mouse
26884383Bzwq3_mbi-zygomatic width QTL 3, 5 week (mouse)10114235905122735905Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined88836456122836456Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084079650122041528Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101497164130530862Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104110021130530862Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10102847852130530862Mouse
14746996Manh69_mmandible shape 69 (mouse)10104763638130530862Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101497164130530862Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
11039496Ltpr5b_mLeishmania tropica response 5b (mouse)10108575094130530862Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084079650122041528Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84079650122041528Mouse
13208554Lgth11_mbody length 11 (mouse)1090835862120835905Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10100986516130530862Mouse
11041664Lmr25_mleishmaniasis resistance 25 (mouse)10108575094130530862Mouse
1300921Skl4_mskeletal size (tail length) 4 (mouse)Not determined1088088254122088391Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105041304130530862Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
1300797Sluc22_msusceptibility to lung cancer 22 (mouse)Not determined1086713608120713756Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
1300796Lmr5_mleishmaniasis resistance 5 (mouse)Not determined10116220635122179828Mouse
10412078Hylaq3_mHyperlocomotor activity related QTL 3 (mouse)Not determined10111568226117986649Mouse
11039516Ltpr5_mLeishmania tropica response 5 (mouse)1090506901125575232Mouse
4142089Obrq9_mobesity resistance QTL 9 (mouse)Not determined108515907130530862Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
26884391Skwq11_mskull length QTL 11, 16 week (mouse)10113535905121635905Mouse
13506931Recrq11_mrecombination rate in male meiosis QTL 11 (mouse)10114335905123635905Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105041304130530862Mouse
1300908Insq4_minsulin QTL 4 (mouse)Not determined1086909085120909229Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83017003117017136Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097217101130530862Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10100986516130530862Mouse
27095902Scvln11_msacral vertebrae length 2, 10 week (mouse)10110035861125435869Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084079650122041528Mouse
11049570Lmr25b_mleishmaniasis resistance 25b (mouse)10108575094130530862Mouse
26884433Zlq2_mzygomatic length QTL 2, 5 week (mouse)10113535905125735869Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097217101130530862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
1357638Cia29_mcollagen induced arthritis 29 (mouse)Not determined1085454982118497353Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105041304130530862Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102506908130530862Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097535905130530862Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
4141153Ltgq2_mliver triglyceride QTL 2 (mouse)Not determined108515907130530862Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97758644130530862Mouse
4141269Ipng2_mimprinted postnatal growth 2 (mouse)Not determined105088254118497353Mouse
1301758Fcsa3_mfemoral cross-sectional area 3 (mouse)Not determined1089927651123927754Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397217101130530862Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103243727130530862Mouse
11353823Homaq2_mhomeostatic model assessment QTL 2 (mouse)10110453347125515907Mouse
11049563Lmr25a_mleishmaniasis resistance 25a (mouse)10108575094130530862Mouse
11353822Insq12_minsulin QTL 12 (mouse)10110453347125515907Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84079650122041528Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10102902508130530862Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099220635130530862Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226725Tibw1_mtibia width 1, proximal, 5 week (mouse)10102735861123235905Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105179713130530862Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099220635130530862Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097217101130530862Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105179713130530862Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099220635130530862Mouse
27226722Tibw7_mtibia width 7, proximal, 16 week (mouse)10108635861125435869Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105179713130530862Mouse

Markers in Region
WI-19751  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810117,051,023 - 117,051,276UniSTSGRCm38
MGSCv3710116,488,079 - 116,488,332UniSTSGRCm37
Celera10118,994,176 - 118,994,429UniSTS
Cytogenetic Map10D2UniSTS
RH143421  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810117,057,237 - 117,057,897UniSTSGRCm38
MGSCv3710116,494,293 - 116,494,953UniSTSGRCm37
Celera10119,000,390 - 119,001,050UniSTS
Cytogenetic Map10D2UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001358767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA023539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB022156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB041570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL589661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU755483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY075050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ076140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z31553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000047672   ⟹   ENSMUSP00000036288
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10116,886,906 - 116,899,719 (-)Ensembl
GRCm38.p6 Ensembl10117,051,001 - 117,063,814 (-)Ensembl
Ensembl Acc Id: ENSMUST00000218059   ⟹   ENSMUSP00000151958
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10116,897,410 - 116,899,280 (-)Ensembl
GRCm38.p6 Ensembl10117,061,505 - 117,063,375 (-)Ensembl
Ensembl Acc Id: ENSMUST00000218502
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10116,890,804 - 116,893,729 (-)Ensembl
GRCm38.p6 Ensembl10117,054,899 - 117,057,824 (-)Ensembl
Ensembl Acc Id: ENSMUST00000218719   ⟹   ENSMUSP00000151890
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10116,897,251 - 116,899,664 (-)Ensembl
GRCm38.p6 Ensembl10117,061,346 - 117,063,759 (-)Ensembl
Ensembl Acc Id: ENSMUST00000219036   ⟹   ENSMUSP00000151587
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10116,896,551 - 116,899,280 (-)Ensembl
GRCm38.p6 Ensembl10117,060,646 - 117,063,375 (-)Ensembl
Ensembl Acc Id: ENSMUST00000219573   ⟹   ENSMUSP00000151306
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10116,896,714 - 116,899,668 (-)Ensembl
GRCm38.p6 Ensembl10117,060,809 - 117,063,763 (-)Ensembl
Ensembl Acc Id: ENSMUST00000219690   ⟹   ENSMUSP00000152005
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10116,886,911 - 116,890,806 (-)Ensembl
GRCm38.p6 Ensembl10117,051,006 - 117,054,901 (-)Ensembl
RefSeq Acc Id: NM_001358767   ⟹   NP_001345696
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910116,886,902 - 116,899,280 (-)NCBI
GRCm3810117,050,997 - 117,063,375 (-)NCBI
Sequence:
RefSeq Acc Id: NM_007636   ⟹   NP_031662
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910116,886,902 - 116,899,757 (-)NCBI
GRCm3810117,050,997 - 117,063,852 (-)NCBI
MGSCv3710116,488,054 - 116,500,870 (-)RGD
Celera10118,994,151 - 119,006,966 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_031662   ⟸   NM_007636
- UniProtKB: Q9R1U0 (UniProtKB/Swiss-Prot),   P80314 (UniProtKB/Swiss-Prot),   Q542X7 (UniProtKB/TrEMBL),   Q9JJD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345696   ⟸   NM_001358767
- UniProtKB: P80314 (UniProtKB/Swiss-Prot),   Q9R1U0 (UniProtKB/Swiss-Prot),   Q542X7 (UniProtKB/TrEMBL),   Q9JJD8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000151958   ⟸   ENSMUST00000218059
Ensembl Acc Id: ENSMUSP00000151890   ⟸   ENSMUST00000218719
Ensembl Acc Id: ENSMUSP00000151587   ⟸   ENSMUST00000219036
Ensembl Acc Id: ENSMUSP00000152005   ⟸   ENSMUST00000219690
Ensembl Acc Id: ENSMUSP00000151306   ⟸   ENSMUST00000219573
Ensembl Acc Id: ENSMUSP00000036288   ⟸   ENSMUST00000047672

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P80314-F1-model_v2 AlphaFold P80314 1-535 view protein structure

Promoters
RGD ID:6848977
Promoter ID:MM_XEF:868
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   MEF_B6
Transcripts:NM_001005905,   NM_001006756,   NM_001012533,   NM_001018416,   NM_001034239,   NM_001046644,   NM_001086919,   NM_001140133,   NM_001142262,   NM_001170520,   NM_006431,   NM_122097,   NM_132296,   NM_171985,   NM_176715,   NM_201455
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610116,499,681 - 116,500,362 (-)MPROMDB
RGD ID:6819090
Promoter ID:MM_KWN:5685
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_007636
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610116,500,481 - 116,501,132 (-)MPROMDB
RGD ID:8673318
Promoter ID:EPDNEW_M14690
Type:initiation region
Name:Cct2_1
Description:Mus musculus chaperonin containing Tcp1, subunit 2 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810117,063,773 - 117,063,833EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107186 AgrOrtholog
Ensembl Genes ENSMUSG00000034024 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047672 ENTREZGENE
  ENSMUST00000047672.9 UniProtKB/Swiss-Prot
  ENSMUST00000218059.2 UniProtKB/TrEMBL
  ENSMUST00000218719.2 UniProtKB/TrEMBL
  ENSMUST00000219036.2 UniProtKB/TrEMBL
  ENSMUST00000219573.2 UniProtKB/TrEMBL
  ENSMUST00000219690.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.560.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Chap_CCT_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chaperone_TCP-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chaperonin_TCP-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cpn60/TCP-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GroEL-like_apical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP-1_chaperonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12461 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:107186 ENTREZGENE
NCBI Gene 12461 ENTREZGENE
PANTHER PTHR11353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cct2 PhenoGen
PRINTS TCOMPLEXTCP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TCP1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCP1_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48592 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52029 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54849 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1W2P6Q3_MOUSE UniProtKB/TrEMBL
  A0A1W2P7B7_MOUSE UniProtKB/TrEMBL
  A0A1W2P828_MOUSE UniProtKB/TrEMBL
  A0A1W2P871_MOUSE UniProtKB/TrEMBL
  A0A1W2P8B6_MOUSE UniProtKB/TrEMBL
  P80314 ENTREZGENE
  Q542X7 ENTREZGENE, UniProtKB/TrEMBL
  Q9JJD8 ENTREZGENE, UniProtKB/TrEMBL
  Q9R1U0 ENTREZGENE
  TCPB_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q9R1U0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Cct2  chaperonin containing TCP1 subunit 2  Cct2  chaperonin containing Tcp1, subunit 2 (beta)  Symbol and/or name change 5135510 APPROVED