Kcna1 (potassium voltage-gated channel, shaker-related subfamily, member 1) - Rat Genome Database

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Gene: Kcna1 (potassium voltage-gated channel, shaker-related subfamily, member 1) Mus musculus
Analyze
Symbol: Kcna1
Name: potassium voltage-gated channel, shaker-related subfamily, member 1
RGD ID: 1552897
MGI Page MGI
Description: Enables delayed rectifier potassium channel activity. Involved in several processes, including cellular response to magnesium ion; detection of mechanical stimulus involved in sensory perception; and nervous system development. Located in several cellular components, including axon; cell surface; and perikaryon. Part of voltage-gated potassium channel complex. Is active in axon initial segment. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; immune system; and nervous system. Used to study epilepsy; episodic ataxia type 1; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in episodic ataxia type 1. Orthologous to human KCNA1 (potassium voltage-gated channel subfamily A member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI840627; brain potassium channel protein-1; Kca1-1; Kv1.; Kv1.1; MBK1; mcep; mceph; megencephaly; MGC124402; Mk-1; MKI; potassium voltage gated channel, shaker related subfamily, member 1; potassium voltage-gated channel subfamily A member 1; Sh; Shak; voltage-gated potassium channel subunit Kv1.1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396126,613,426 - 126,622,764 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6126,617,360 - 126,623,347 (-)EnsemblGRCm39 Ensembl
GRCm386126,636,463 - 126,645,801 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6126,640,397 - 126,646,384 (-)EnsemblGRCm38mm10GRCm38
MGSCv376126,586,481 - 126,595,819 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366126,606,016 - 126,610,415 (-)NCBIMGSCv36mm8
Celera6128,306,063 - 128,315,400 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map661.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal action potential  (IAGP)
abnormal astrocyte morphology  (IAGP)
abnormal behavior  (IAGP)
abnormal brain development  (IAGP)
abnormal brain morphology  (IAGP)
abnormal brain size  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal CNS synaptic transmission  (IAGP)
abnormal gait  (IAGP)
abnormal hearing physiology  (IAGP)
abnormal ictal brain wave pattern  (IAGP)
abnormal impulse conducting system conduction  (IAGP)
abnormal inhibitory postsynaptic currents  (IAGP)
abnormal locomotor behavior  (IAGP)
abnormal mitochondrial ATP synthesis coupled electron transport  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal paired-pulse facilitation  (IAGP)
abnormal PNS synaptic transmission  (IAGP)
abnormal posture  (IAGP)
abnormal reflex  (IAGP)
abnormal sexual interaction  (IAGP)
ataxia  (IAGP)
atrioventricular block  (IAGP)
chromodacryorrhea  (IAGP)
convulsive seizures  (IAGP)
decreased body size  (IAGP)
decreased chemical nociceptive threshold  (IAGP)
decreased chemically-elicited antinociception  (IAGP)
decreased heart rate  (IAGP)
decreased nerve fiber response threshold  (IAGP)
decreased paired-pulse ratio  (IAGP)
decreased thermal nociceptive threshold  (IAGP)
ear inflammation  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enlarged hippocampus  (IAGP)
excessive tearing  (IAGP)
eye inflammation  (IAGP)
impaired balance  (IAGP)
impaired swimming  (IAGP)
increased blinking frequency  (IAGP)
increased brain size  (IAGP)
increased brain weight  (IAGP)
increased startle reflex  (IAGP)
increased susceptibility to pharmacologically induced seizures  (IAGP)
myoclonus  (IAGP)
oxidative stress  (IAGP)
porphyria  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
seizures  (IAGP)
tonic-clonic seizures  (IAGP)
tremors  (IAGP)
ventricular premature beat  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures. Ishida S, etal., Brain Res. 2012 Jan 30;1435:154-66. doi: 10.1016/j.brainres.2011.11.023. Epub 2011 Nov 13.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1285906   PMID:1377421   PMID:1383027   PMID:1425474   PMID:1723658   PMID:2305265   PMID:2333511   PMID:2451788   PMID:7768898   PMID:7799925   PMID:7843783   PMID:7905852  
PMID:8020965   PMID:8034307   PMID:8043949   PMID:8046438   PMID:8120633   PMID:8126562   PMID:8226976   PMID:8254371   PMID:8358568   PMID:8361541   PMID:8530061   PMID:8889548  
PMID:8995755   PMID:9027502   PMID:9119363   PMID:9286706   PMID:9321475   PMID:9488722   PMID:9501192   PMID:9507200   PMID:9581771   PMID:9606360   PMID:9671659   PMID:9718989  
PMID:9736643   PMID:9852577   PMID:10051663   PMID:10191303   PMID:10349636   PMID:10407018   PMID:10441735   PMID:10521601   PMID:10575255   PMID:11015449   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:11301201   PMID:12477932   PMID:12611922   PMID:12612586   PMID:12763069   PMID:12907802   PMID:12963709   PMID:14534254   PMID:14636320   PMID:14686896   PMID:14686897  
PMID:15361858   PMID:15381686   PMID:15800194   PMID:15843481   PMID:16141072   PMID:16141073   PMID:16305740   PMID:16551741   PMID:16602821   PMID:16672305   PMID:16723544   PMID:16919269  
PMID:16985003   PMID:16990009   PMID:17227368   PMID:17250763   PMID:17315199   PMID:17473172   PMID:17634333   PMID:17651419   PMID:17977745   PMID:17982453   PMID:18053989   PMID:18424000  
PMID:18509034   PMID:18579745   PMID:18760366   PMID:18926893   PMID:19208226   PMID:19243017   PMID:19244508   PMID:19307729   PMID:19549557   PMID:19625254   PMID:19706400   PMID:20392939  
PMID:20519930   PMID:21224222   PMID:21233214   PMID:21267068   PMID:21483673   PMID:21822598   PMID:21859894   PMID:21873635   PMID:21966978   PMID:21984254   PMID:22302114   PMID:22345400  
PMID:22396426   PMID:22411008   PMID:22609489   PMID:22612818   PMID:22641786   PMID:22794259   PMID:23063513   PMID:23345237   PMID:23466697   PMID:23473320   PMID:23836929   PMID:23864368  
PMID:23903368   PMID:24032507   PMID:24194600   PMID:24270080   PMID:24767949   PMID:24885223   PMID:24952961   PMID:25377007   PMID:25602577   PMID:25653379   PMID:25707359   PMID:25798587  
PMID:25855492   PMID:26112121   PMID:26269648   PMID:26288989   PMID:26580832   PMID:26724401   PMID:26840208   PMID:27346881   PMID:27381274   PMID:27507650   PMID:27527983   PMID:27626380  
PMID:27986658   PMID:28065805   PMID:28193892   PMID:28249786   PMID:28283561   PMID:28334922   PMID:28671696   PMID:29171006   PMID:29193044   PMID:29222517   PMID:29265344   PMID:29327348  
PMID:29409952   PMID:29476105   PMID:29804833   PMID:29963986   PMID:30009381   PMID:30224470   PMID:30261354   PMID:30427720   PMID:30974168   PMID:31410614   PMID:31978607   PMID:32030748  
PMID:32325033   PMID:33427415   PMID:33484493   PMID:33901631   PMID:34018923   PMID:34312446   PMID:34321999   PMID:34935172   PMID:34964210   PMID:35892317   PMID:36417872   PMID:36417873  
PMID:36604605   PMID:36808153   PMID:37142655   PMID:37408217   PMID:37644198   PMID:38187761   PMID:38355793   PMID:38995010  


Genomics

Comparative Map Data
Kcna1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396126,613,426 - 126,622,764 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6126,617,360 - 126,623,347 (-)EnsemblGRCm39 Ensembl
GRCm386126,636,463 - 126,645,801 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6126,640,397 - 126,646,384 (-)EnsemblGRCm38mm10GRCm38
MGSCv376126,586,481 - 126,595,819 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366126,606,016 - 126,610,415 (-)NCBIMGSCv36mm8
Celera6128,306,063 - 128,315,400 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map661.57NCBI
KCNA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38124,909,905 - 4,918,256 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl124,909,905 - 4,918,256 (+)EnsemblGRCh38hg38GRCh38
GRCh37125,019,071 - 5,027,422 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,889,334 - 4,897,683 (+)NCBINCBI36Build 36hg18NCBI36
Build 34124,890,805 - 4,892,293NCBI
Celera126,640,916 - 6,649,264 (+)NCBICelera
Cytogenetic Map12p13.32NCBI
HuRef124,875,853 - 4,884,200 (+)NCBIHuRef
CHM1_1125,018,738 - 5,027,087 (+)NCBICHM1_1
T2T-CHM13v2.0124,916,952 - 4,925,303 (+)NCBIT2T-CHM13v2.0
Kcna1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84161,150,378 - 161,160,051 (-)NCBIGRCr8
mRatBN7.24159,464,223 - 159,472,905 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4159,464,188 - 159,472,682 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4165,699,172 - 165,700,917 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04161,482,081 - 161,483,826 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04160,116,108 - 160,117,853 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04159,190,781 - 159,192,526 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4159,190,804 - 159,192,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04226,188,851 - 226,190,596 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44163,011,777 - 163,013,522 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14163,254,845 - 163,259,290 (-)NCBI
Celera4148,186,141 - 148,187,886 (-)NCBICelera
Cytogenetic Map4q42NCBI
Kcna1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554132,703,030 - 2,711,612 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554132,703,030 - 2,711,612 (+)NCBIChiLan1.0ChiLan1.0
KCNA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21010,458,271 - 10,468,092 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,455,043 - 10,464,850 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,027,333 - 5,037,136 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1124,949,464 - 4,957,811 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl124,950,938 - 4,952,425 (+)Ensemblpanpan1.1panPan2
KCNA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12739,928,347 - 39,936,753 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2739,933,825 - 39,935,312 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha276,745,890 - 6,747,377 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02740,289,956 - 40,291,443 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2740,289,873 - 40,292,984 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12740,179,028 - 40,180,515 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02740,203,981 - 40,205,468 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0276,156,901 - 6,158,388 (+)NCBIUU_Cfam_GSD_1.0
LOC101959799
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721327,488,417 - 27,489,932 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004937109142,711 - 144,198 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004937109142,711 - 144,257 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl565,561,962 - 65,565,116 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1565,556,837 - 65,565,880 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2567,763,338 - 67,770,194 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1114,956,824 - 4,963,732 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl114,956,856 - 4,958,343 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660633,283,565 - 3,291,460 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcna1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248601,915,344 - 1,923,062 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248601,915,108 - 1,923,071 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kcna1
353 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:2375
Count of miRNA genes:830
Interacting mature miRNAs:1125
Transcripts:ENSMUST00000055168
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4141611Btts_mbitterness tasting (mouse)Not determined6125333609134096586Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104480321127019938Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141064Ath37_matherosclerosis 37 (mouse)Not determined6116641858128495988Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse

Markers in Region
RH131723  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,636,556 - 126,636,740UniSTSGRCm38
MGSCv376126,586,574 - 126,586,758UniSTSGRCm37
Celera6128,306,156 - 128,306,340UniSTS
Cytogenetic Map6F1-F3UniSTS
AI840627  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,644,402 - 126,644,517UniSTSGRCm38
MGSCv376126,594,420 - 126,594,535UniSTSGRCm37
Celera6128,314,002 - 128,314,117UniSTS
Cytogenetic Map6F1-F3UniSTS
Whitehead/MRC_RH61284.33UniSTS
UniSTS:224835  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,641,667 - 126,641,819UniSTSGRCm38
MGSCv376126,591,685 - 126,591,837UniSTSGRCm37
Celera6128,311,267 - 128,311,419UniSTS
Cytogenetic Map6F1-F3UniSTS
GDB:435453  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,642,236 - 126,642,983UniSTSGRCm38
MGSCv376126,592,254 - 126,593,001UniSTSGRCm37
Celera6128,311,836 - 128,312,583UniSTS
Cytogenetic Map6F1-F3UniSTS
RH11273  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,636,544 - 126,636,682UniSTSGRCm38
MGSCv376126,586,562 - 126,586,700UniSTSGRCm37
Celera6128,306,144 - 128,306,282UniSTS
Cytogenetic Map6F1-F3UniSTS
PMC20739P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,643,192 - 126,643,395UniSTSGRCm38
MGSCv376126,593,210 - 126,593,413UniSTSGRCm37
Celera6128,312,792 - 128,312,995UniSTS
Cytogenetic Map6F1-F3UniSTS
PMC20739P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,643,207 - 126,643,395UniSTSGRCm38
MGSCv376126,593,225 - 126,593,413UniSTSGRCm37
Celera6128,312,807 - 128,312,995UniSTS
Cytogenetic Map6F1-F3UniSTS
D6Tem3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,646,260 - 126,646,409UniSTSGRCm38
MGSCv376126,596,278 - 126,596,427UniSTSGRCm37
Celera6128,315,859 - 128,316,008UniSTS
Cytogenetic Map6F1-F3UniSTS
cM Map661.0UniSTS
Kcna1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,641,725 - 126,641,861UniSTSGRCm38
MGSCv376126,591,743 - 126,591,879UniSTSGRCm37
Celera6128,311,325 - 128,311,461UniSTS
Cytogenetic Map6F1-F3UniSTS
cM Map661.0UniSTS
Kcna1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,643,102 - 126,643,216UniSTSGRCm38
GRCm383107,036,622 - 107,036,737UniSTSGRCm38
MGSCv376126,593,120 - 126,593,234UniSTSGRCm37
MGSCv373106,839,540 - 106,839,655UniSTSGRCm37
Celera6128,312,702 - 128,312,816UniSTS
Celera3109,365,890 - 109,366,005UniSTS
Cytogenetic Map3F2.3UniSTS
Cytogenetic Map6F1-F3UniSTS
cM Map661.0UniSTS
RH70531  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386126,639,496 - 126,640,640UniSTSGRCm38
MGSCv376126,589,514 - 126,590,658UniSTSGRCm37
Celera6128,309,096 - 128,310,240UniSTS
Cytogenetic Map6F1-F3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000055168   ⟹   ENSMUSP00000055225
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6126,617,360 - 126,621,759 (-)Ensembl
GRCm38.p6 Ensembl6126,640,397 - 126,644,796 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203094   ⟹   ENSMUSP00000144947
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6126,618,627 - 126,621,776 (-)Ensembl
GRCm38.p6 Ensembl6126,641,664 - 126,644,813 (-)Ensembl
Ensembl Acc Id: ENSMUST00000205171
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6126,620,738 - 126,623,347 (-)Ensembl
GRCm38.p6 Ensembl6126,643,775 - 126,646,384 (-)Ensembl
RefSeq Acc Id: NM_010595   ⟹   NP_034725
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396126,613,426 - 126,622,764 (-)NCBI
GRCm386126,636,463 - 126,645,801 (-)ENTREZGENE
MGSCv376126,586,481 - 126,595,819 (-)RGD
Celera6128,306,063 - 128,315,400 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034725   ⟸   NM_010595
- UniProtKB: P16388 (UniProtKB/Swiss-Prot),   Q2KHP0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000144947   ⟸   ENSMUST00000203094
Ensembl Acc Id: ENSMUSP00000055225   ⟸   ENSMUST00000055168
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16388-F1-model_v2 AlphaFold P16388 1-495 view protein structure

Promoters
RGD ID:6839525
Promoter ID:MM_KWN:47674
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_010595
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366126,594,751 - 126,595,702 (-)MPROMDB
RGD ID:6891084
Promoter ID:EPDNEW_M8993
Type:initiation region
Name:Kcna1_1
Description:Mus musculus potassium voltage-gated channel, shaker-relatedsubfamily, member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386126,644,796 - 126,644,856EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96654 AgrOrtholog
Ensembl Genes ENSMUSG00000047976 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000055168 ENTREZGENE
  ENSMUST00000055168.5 UniProtKB/Swiss-Prot
  ENSMUST00000203094.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Potassium Channel Kv1.1, Chain A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv1.1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VG_K_chnl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16485 UniProtKB/Swiss-Prot
MGD MGI:96654 ENTREZGENE
NCBI Gene 16485 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11537 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kcna1 PhenoGen
PRINTS KCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KV11CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHAKERCHANEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt KCNA1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q2KHP0 ENTREZGENE, UniProtKB/TrEMBL
  Q3TZ64_MOUSE UniProtKB/TrEMBL
  Q8CA58_MOUSE UniProtKB/TrEMBL