Prkaca (protein kinase, cAMP dependent, catalytic, alpha) - Rat Genome Database

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Gene: Prkaca (protein kinase, cAMP dependent, catalytic, alpha) Mus musculus
Analyze
Symbol: Prkaca
Name: protein kinase, cAMP dependent, catalytic, alpha
RGD ID: 1552640
MGI Page MGI
Description: Enables several functions, including ATP binding activity; cAMP-dependent protein kinase activity; and metal ion binding activity. Involved in several processes, including cellular response to glucagon stimulus; positive regulation of insulin secretion; and regulation of carbohydrate metabolic process. Acts upstream of with a positive effect on protein export from nucleus. Acts upstream of or within several processes, including cellular response to parathyroid hormone stimulus; neural tube development; and protein phosphorylation. Located in several cellular components, including acrosomal vesicle; ciliary base; and sperm flagellum. Part of cAMP-dependent protein kinase complex. Is active in cytosol and glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and musculature. Human ortholog(s) of this gene implicated in adrenal cortical adenoma; congestive heart failure; fibrolamellar carcinoma; and primary pigmented nodular adrenocortical disease 4. Orthologous to human PRKACA (protein kinase cAMP-activated catalytic subunit alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C; cAMP-dependent protein kinase catalytic subunit alpha; cAMP-dependent protein kinase catalytic subunit alpha isoform; cAMP-dependent protein kinase catalytic subunit C alpha 2; Cs; P; Pk; PKA; PKA C-alpha; Pkaca; PKCD; sperm cAMP-dependent protein kinase catalytic subunit
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Prkaca-ps1  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,699,607 - 84,723,073 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl884,699,622 - 84,723,072 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38883,972,978 - 83,996,444 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,972,993 - 83,996,443 (+)Ensemblmm10GRCm38
MGSCv37886,496,877 - 86,520,344 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36886,863,093 - 86,886,544 (+)NCBIMGSCv36mm8
Celera888,266,474 - 88,289,645 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map840.22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-tert-butylhydroquinone  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-aminopyridine  (ISO)
6-propyl-2-thiouracil  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
aripiprazole  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (EXP)
asbestos  (ISO)
atorvastatin calcium  (ISO)
atrazine  (ISO)
BAPTA  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
Bifeprunox  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bucladesine  (ISO)
buprenorphine  (ISO)
buspirone  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cannabidiol  (ISO)
capsaicin  (EXP)
captopril  (ISO)
CGP 52608  (ISO)
chaetocin  (ISO)
chlormequat chloride  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (EXP,ISO)
copper(II) sulfate  (EXP)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dexamethasone  (EXP)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
Doramectin  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fluoranthene  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
Gastrodin  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
gentamycin  (ISO)
glycitein  (ISO)
glycitin  (ISO)
glyphosate  (ISO)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (EXP)
hydroxysafflor yellow A  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
JTE-013  (ISO)
KT 5720  (ISO)
Lappaconitine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
Licarin A  (EXP)
maneb  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
N,N-diethyl-m-toluamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nitrates  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
ochratoxin A  (ISO)
oxycodone  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregabalin  (ISO)
propiconazole  (ISO)
prostaglandin E2  (ISO)
Pyridostigmine bromide  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
reserpine  (EXP)
resveratrol  (ISO)
roflumilast  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
streptozocin  (EXP)
sulfadimethoxine  (ISO)
sulindac  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
taurine  (ISO)
taurolithocholic acid  (ISO)
tebufenpyrad  (ISO)
telmisartan  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
Tylophorine  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vismodegib  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (IBA,IDA,IMP)
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (IEA,ISO)
cAMP/PKA signal transduction  (ISO)
cellular response to cold  (IMP)
cellular response to glucagon stimulus  (IGI)
cellular response to glucose stimulus  (IEA,ISO)
cellular response to heat  (IEA,ISO,ISS)
cellular response to nutrient levels  (ISO)
cellular response to parathyroid hormone stimulus  (IMP)
dorsal/ventral neural tube patterning  (IGI)
interleukin-2-mediated signaling pathway  (ISO)
intracellular potassium ion homeostasis  (IEA,ISO)
mesoderm formation  (IGI)
modulation of chemical synaptic transmission  (IMP)
mRNA processing  (IEA,ISO)
negative regulation of glycolytic process through fructose-6-phosphate  (IDA,IMP)
negative regulation of meiotic cell cycle  (ISO)
negative regulation of meiotic cell cycle process involved in oocyte maturation  (ISO)
negative regulation of smoothened signaling pathway  (IEA,IGI)
negative regulation of TORC1 signaling  (IEA,ISO,ISS)
negative regulation of transcription by RNA polymerase II  (ISO)
neural tube closure  (IEA,IGI)
peptidyl-serine phosphorylation  (IDA,IMP,ISO)
peptidyl-threonine phosphorylation  (IDA)
positive regulation of cell population proliferation  (ISO)
positive regulation of cholesterol biosynthetic process  (IEA,ISO)
positive regulation of gluconeogenesis  (IDA)
positive regulation of insulin secretion  (IDA,IMP)
positive regulation of phagocytosis  (IEA,ISO)
positive regulation of protein export from nucleus  (IMP)
postsynaptic modulation of chemical synaptic transmission  (EXP,IDA)
protein autophosphorylation  (IDA)
protein export from nucleus  (IDA,IMP,ISO)
protein localization to lipid droplet  (IMP)
protein phosphorylation  (IDA,ISO)
regulation of bicellular tight junction assembly  (IEA,ISO)
regulation of cell cycle  (IDA)
regulation of cellular respiration  (ISO)
regulation of osteoblast differentiation  (IEA,ISO)
regulation of proteasomal protein catabolic process  (IEA,ISO)
regulation of protein processing  (IEA,IGI)
regulation of synaptic transmission, glutamatergic  (ISO)
sperm capacitation  (IDA)
spontaneous exocytosis of neurotransmitter  (ISO)
TORC1 signaling  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
apoptotic cell death pathway  (IEA)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bile acid transport pathway  (IEA)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
dilated cardiomyopathy pathway  (IEA)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway   (ISO)
dopamine signaling pathway  (ISO)
eicosanoid signaling pathway  (ISO)
Entamoebiasis pathway  (IEA)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
glutamate signaling pathway  (IEA)
gonadotropin-releasing hormone signaling pathway  (IEA)
granulocyte-macrophage colony-stimulating factor signaling pathway   (ISO)
Hedgehog signaling pathway  (IEA,ISO)
ibutilide pharmacodynamics pathway   (ISO)
insulin signaling pathway  (IEA)
interleukin-3 signaling pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
long term potentiation  (IEA)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway   (ISO)
mitogen activated protein kinase signaling pathway  (IEA)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway   (ISO)
phosphatidylinositol 3-kinase-Akt signaling pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prion disease pathway  (IEA)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway   (ISO)
protein kinase A (PKA) signaling pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
syndecan signaling pathway  (ISO)
timolol pharmacodynamics pathway   (ISO)
vascular endothelial growth factor signaling pathway   (ISO)
vasopressin signaling pathway via receptor type 2  (IEA)
verapamil pharmacodynamics pathway  (ISO)
Wnt signaling pathway  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal bone mineralization  (IAGP)
abnormal compact bone morphology  (IAGP)
abnormal dorsal root ganglion morphology  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal glycogen homeostasis  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal neuron specification  (IAGP)
abnormal periosteum morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal sperm motility  (IAGP)
abnormal spine curvature  (IAGP)
abnormal vertebral arch morphology  (IAGP)
abnormal vertebral column morphology  (IAGP)
asthenozoospermia  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased circulating insulin level  (IAGP)
decreased insulin secretion  (IAGP)
decreased liver glycogen level  (IAGP)
decreased trabecular bone thickness  (IAGP)
decreased urine protein level  (IAGP)
disorganized dorsal root ganglion  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
exencephaly  (IAGP)
impaired fertilization  (IAGP)
impaired glucose tolerance  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased neural tube apoptosis  (IAGP)
increased osteochondroma incidence  (IAGP)
increased osteosarcoma incidence  (IAGP)
increased skeletal tumor incidence  (IAGP)
male infertility  (IAGP)
pericardial edema  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
spina bifida  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. SCP2-mediated cholesterol membrane trafficking promotes the growth of pituitary adenomas via Hedgehog signaling activation. Ding X, etal., J Exp Clin Cancer Res. 2019 Sep 13;38(1):404. doi: 10.1186/s13046-019-1411-9.
2. CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma. Engelholm LH, etal., Gastroenterology. 2017 Dec;153(6):1662-1673.e10. doi: 10.1053/j.gastro.2017.09.008. Epub 2017 Sep 18.
3. Regulation of mRNA expression involved in Ras and PKA signal pathways during rat hypoglossal nerve regeneration. Kiryu S, etal., Brain Res Mol Brain Res. 1995 Mar;29(1):147-56.
4. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Marx SO, etal., Cell. 2000 May 12;101(4):365-76.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Impairment of cerebral cAMP-mediated signal transduction system and of spatial memory function after microsphere embolism in rats. Nagakura A, etal., Neuroscience. 2002;113(3):519-28.
8. PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells. Obara Y, etal., J Cell Sci. 2004 Dec 1;117(Pt 25):6085-94. Epub 2004 Nov 16.
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
14. Mouse MP Annotation Import Pipeline RGD automated import pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma. Riggle KM, etal., Pediatr Res. 2016 Jul;80(1):110-8. doi: 10.1038/pr.2016.36. Epub 2016 Mar 8.
18. Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome. Sato Y, etal., Science. 2014 May 23;344(6186):917-20. doi: 10.1126/science.1252328.
19. Cardiac troponin C-L29Q, related to hypertrophic cardiomyopathy, hinders the transduction of the protein kinase A dependent phosphorylation signal from cardiac troponin I to C. Schmidtmann A, etal., FEBS J. 2005 Dec;272(23):6087-97.
20. Localized effects of cAMP mediated by distinct routes of protein kinase A. Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67.
21. The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line. Yang GM, etal., Neurotox Res. 2020 Apr;37(4):926-935. doi: 10.1007/s12640-019-00150-7. Epub 2020 Jan 4.
22. A developmental switch in the signaling cascades for LTP induction. Yasuda H, etal., Nat Neurosci. 2003 Jan;6(1):15-6.
23. DARPP-32, Jack of All Trades... Master of Which? Yger M and Girault JA, Front Behav Neurosci. 2011 Sep 8;5:56. doi: 10.3389/fnbeh.2011.00056. eCollection 2011.
Additional References at PubMed
PMID:1584809   PMID:1862342   PMID:2342480   PMID:2619996   PMID:2833513   PMID:3023318   PMID:3456589   PMID:7775586   PMID:7873880   PMID:7905001   PMID:8443157   PMID:8548807  
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PMID:10767319   PMID:10805756   PMID:10841548   PMID:10862698   PMID:10913627   PMID:10922068   PMID:10945997   PMID:10982398   PMID:11042159   PMID:11050131   PMID:11076861   PMID:11141074  
PMID:11217851   PMID:11559352   PMID:11698644   PMID:11799117   PMID:11804588   PMID:11875122   PMID:11886853   PMID:12004056   PMID:12034735   PMID:12051828   PMID:12123716   PMID:12139926  
PMID:12180908   PMID:12193547   PMID:12200423   PMID:12372837   PMID:12453050   PMID:12477932   PMID:12614615   PMID:12646569   PMID:12801936   PMID:12837291   PMID:12931191   PMID:14673008  
PMID:14681479   PMID:14724137   PMID:14757059   PMID:14967031   PMID:15023366   PMID:15039079   PMID:15039316   PMID:15111495   PMID:15133036   PMID:15212707   PMID:15340140   PMID:15345747  
PMID:15347661   PMID:15465019   PMID:15489334   PMID:15529118   PMID:15550674   PMID:15557275   PMID:15580572   PMID:15590926   PMID:15618230   PMID:15649893   PMID:15663937   PMID:15692043  
PMID:15724149   PMID:15741175   PMID:15753322   PMID:15782199   PMID:15851520   PMID:15860459   PMID:15889150   PMID:16129693   PMID:16141072   PMID:16141073   PMID:16155866   PMID:16169904  
PMID:16172130   PMID:16280415   PMID:16289764   PMID:16303765   PMID:16436600   PMID:16481613   PMID:16484320   PMID:16514061   PMID:16602821   PMID:16625003   PMID:16707791   PMID:16782699  
PMID:16785309   PMID:16793902   PMID:16835269   PMID:16924114   PMID:16956882   PMID:16966355   PMID:16973906   PMID:16990513   PMID:17043310   PMID:17053039   PMID:17075052   PMID:17079783  
PMID:17149706   PMID:17279627   PMID:17290424   PMID:17296605   PMID:17301223   PMID:17322895   PMID:17407158   PMID:17464208   PMID:17478427   PMID:17557924   PMID:17585336   PMID:17651699  
PMID:17855365   PMID:17923693   PMID:17938178   PMID:17972919   PMID:18048352   PMID:18191828   PMID:18202122   PMID:18305402   PMID:18310078   PMID:18316483   PMID:18338389   PMID:18353144  
PMID:18367160   PMID:18380891   PMID:18387001   PMID:18463244   PMID:18467503   PMID:18565730   PMID:18583710   PMID:18606808   PMID:18633139   PMID:18727045   PMID:18758906   PMID:18762248  
PMID:18799693   PMID:18829456   PMID:19035343   PMID:19056373   PMID:19074277   PMID:19113914   PMID:19138662   PMID:19144927   PMID:19223768   PMID:19229884   PMID:19234474   PMID:19356238  
PMID:19389706   PMID:19389708   PMID:19447092   PMID:19560455   PMID:19601643   PMID:19647741   PMID:19706446   PMID:19706594   PMID:19706882   PMID:19723499   PMID:19924297   PMID:20045463  
PMID:20067919   PMID:20103769   PMID:20107112   PMID:20207816   PMID:20363288   PMID:20421483   PMID:20442403   PMID:20525692   PMID:20534695   PMID:20542497   PMID:20591207   PMID:20615971  
PMID:20630779   PMID:20637325   PMID:20716686   PMID:20940146   PMID:21209912   PMID:21267068   PMID:21300294   PMID:21306750   PMID:21406180   PMID:21430226   PMID:21533282   PMID:21559296  
PMID:21614075   PMID:21808064   PMID:21808067   PMID:21835884   PMID:21852354   PMID:21873635   PMID:21888435   PMID:21896757   PMID:21911379   PMID:22007132   PMID:22138346   PMID:22195961  
PMID:22267325   PMID:22323819   PMID:22493239   PMID:22496451   PMID:22641646   PMID:22645447   PMID:22658979   PMID:22733971   PMID:22751671   PMID:22771957   PMID:22794259   PMID:22797923  
PMID:22815846   PMID:22954688   PMID:23028418   PMID:23028752   PMID:23049792   PMID:23055522   PMID:23104882   PMID:23116618   PMID:23159612   PMID:23238728   PMID:23275441   PMID:23292513  
PMID:23324178   PMID:23329830   PMID:23349500   PMID:23362255   PMID:23393127   PMID:23456795   PMID:23458248   PMID:23507145   PMID:23583750   PMID:23593352   PMID:23647065   PMID:23709216  
PMID:23965992   PMID:23981281   PMID:24058535   PMID:24086441   PMID:24101724   PMID:24128762   PMID:24211434   PMID:24260568   PMID:24464040   PMID:24512487   PMID:24556414   PMID:24560667  
PMID:24643070   PMID:24687590   PMID:24691407   PMID:24713698   PMID:24786636   PMID:24828496   PMID:24831015   PMID:24842369   PMID:24905167   PMID:24952961   PMID:25073061   PMID:25193703  
PMID:25275314   PMID:25418045   PMID:25475437   PMID:25512381   PMID:25933021   PMID:25961040   PMID:25970584   PMID:26030372   PMID:26060254   PMID:26158466   PMID:26203188   PMID:26278174  
PMID:26305972   PMID:26387949   PMID:26488807   PMID:26582204   PMID:26618408   PMID:26626075   PMID:26743816   PMID:26833386   PMID:26992826   PMID:27105888   PMID:27156838   PMID:27160897  
PMID:27245613   PMID:27353657   PMID:27498419   PMID:27624192   PMID:27720745   PMID:28115705   PMID:28119464   PMID:28119465   PMID:28420713   PMID:28556983   PMID:28636612   PMID:28661131  
PMID:28671696   PMID:28706196   PMID:28911199   PMID:28973931   PMID:29038164   PMID:29162699   PMID:29183804   PMID:29473541   PMID:29581285   PMID:29967033   PMID:30026308   PMID:30068389  
PMID:30326594   PMID:30385877   PMID:30457570   PMID:30468265   PMID:30652267   PMID:30862682   PMID:31078384   PMID:31176020   PMID:31353306   PMID:31545012   PMID:31935860   PMID:32325033  
PMID:32735622   PMID:32873725   PMID:33120014   PMID:33338547   PMID:34348145   PMID:35672324   PMID:35830806   PMID:36114006   PMID:36232721   PMID:36516777   PMID:36841836   PMID:37142655  
PMID:37169038   PMID:37576597   PMID:38445884   PMID:40429791  


Genomics

Comparative Map Data
Prkaca
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,699,607 - 84,723,073 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl884,699,622 - 84,723,072 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38883,972,978 - 83,996,444 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,972,993 - 83,996,443 (+)Ensemblmm10GRCm38
MGSCv37886,496,877 - 86,520,344 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36886,863,093 - 86,886,544 (+)NCBIMGSCv36mm8
Celera888,266,474 - 88,289,645 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map840.22NCBI
PRKACA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,091,688 - 14,117,762 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1914,091,688 - 14,118,084 (-)Ensemblhg38GRCh38
GRCh371914,202,500 - 14,228,574 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,063,500 - 14,089,559 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341914,063,508 - 14,085,992NCBI
Celera1914,096,777 - 14,122,833 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1913,774,379 - 13,800,126 (-)NCBIHuRef
CHM1_11914,202,926 - 14,228,985 (-)NCBICHM1_1
T2T-CHM13v2.01914,218,299 - 14,244,374 (-)NCBIT2T-CHM13v2.0
Prkaca
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,059,843 - 41,083,189 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1941,059,843 - 41,086,494 (-)EnsemblGRCr8
mRatBN7.21924,155,081 - 24,178,430 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,155,090 - 24,178,430 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1930,976,206 - 30,999,561 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01931,630,613 - 31,653,968 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01933,853,335 - 33,876,684 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01925,095,089 - 25,118,869 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,095,089 - 25,118,860 (+)Ensemblrn6Rnor6.0
Rnor_5.01936,073,104 - 36,096,884 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41925,840,795 - 25,864,786 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1923,703,180 - 23,726,723 (-)NCBICelera
RGSC_v3.11925,845,620 - 25,861,927 (-)NCBI
Cytogenetic Map19q11NCBI
Prkaca
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541532,793,718 - 32,812,930 (-)Ensembl
ChiLan1.0NW_00495541532,794,172 - 32,807,944 (-)NCBIChiLan1.0ChiLan1.0
PRKACA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,024,152 - 19,050,193 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,025,838 - 18,051,874 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01913,657,344 - 13,683,864 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11914,385,183 - 14,406,205 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1914,385,191 - 14,406,205 (-)EnsemblpanPan2panpan1.1
PRKACA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12048,416,730 - 48,425,237 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2048,409,045 - 48,426,669 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2048,283,546 - 48,299,768 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02048,926,811 - 48,944,065 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2048,926,580 - 48,944,481 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12048,138,017 - 48,154,228 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02048,564,570 - 48,580,793 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02048,807,387 - 48,823,603 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Prkaca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118207,588,938 - 207,605,559 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366592,750,537 - 2,765,753 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366592,750,015 - 2,765,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKACA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl265,074,870 - 65,095,551 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1265,074,876 - 65,095,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2265,350,544 - 65,371,236 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKACA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1612,743,752 - 12,759,155 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660746,888,080 - 6,914,845 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkaca
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249011,319,062 - 1,336,744 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249011,319,426 - 1,336,848 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Prkaca
1562 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:420
Count of miRNA genes:275
Interacting mature miRNAs:324
Transcripts:ENSMUST00000005606
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
12904012Cfq10_mconditioned fear QTL 10 (mouse)88079340489740987Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined876411976110412125Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85474046188740637Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85515925889159407Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined871032003105032123Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined876411976110412125Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871740461124622354Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6418673698186736Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86466617698666325Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)882345783116345783Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879808806113809031Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85913640493136404Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined876411976110412125Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined872122809106123021Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86151347995513605Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871829531105829637Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873929123107929226Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7158942790929226Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85233484386334843Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881819296115819296Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined871032003105032123Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)874126628126826739Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined879245241113245331Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71740461124622354Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined876402145110402251Mouse

Markers in Region
RH128078  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38883,996,060 - 83,996,278UniSTSGRCm38
MGSCv37886,519,959 - 86,520,177UniSTSGRCm37
Celera888,289,260 - 88,289,478UniSTS
Cytogenetic Map8C3UniSTS
RH94810  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X161,484,061 - 161,484,176UniSTSGRCm38
GRCm38883,995,965 - 83,996,079UniSTSGRCm38
MGSCv37886,519,864 - 86,519,978UniSTSGRCm37
MGSCv37X157,921,993 - 157,922,108UniSTSGRCm37
Celera888,289,165 - 88,289,279UniSTS
CeleraX144,721,668 - 144,721,783UniSTS
Cytogenetic Map8C3UniSTS
Prkaca  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37X157,921,884 - 157,922,048UniSTSGRCm37
MGSCv37886,519,923 - 86,520,106UniSTSGRCm37
Celera888,289,224 - 88,289,407UniSTS
CeleraX144,721,559 - 144,721,723UniSTS
Cytogenetic Map8C3UniSTS
cM Map8 UniSTS
PMC18620P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38883,976,823 - 83,977,094UniSTSGRCm38
MGSCv37886,500,722 - 86,500,993UniSTSGRCm37
Celera888,270,321 - 88,270,593UniSTS
Cytogenetic Map8C3UniSTS
Prkaca  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8C3UniSTS
Prkaca  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38883,996,024 - 83,996,207UniSTSGRCm38
GRCm38X161,483,952 - 161,484,116UniSTSGRCm38
MGSCv37X157,921,884 - 157,922,048UniSTSGRCm37
MGSCv37886,519,923 - 86,520,106UniSTSGRCm37
Celera888,289,224 - 88,289,407UniSTS
CeleraX144,721,559 - 144,721,723UniSTS
Cytogenetic Map8C3UniSTS
cM Map8 UniSTS
Prkaca  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8C3UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001277898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC156028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF224719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF239743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ031203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU059097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB248596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD807077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN566056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M12303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000005606   ⟹   ENSMUSP00000005606
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl884,699,622 - 84,723,072 (+)Ensembl
GRCm38.p6 Ensembl883,972,993 - 83,996,443 (+)Ensembl
Ensembl Acc Id: ENSMUST00000211558   ⟹   ENSMUSP00000147256
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl884,703,512 - 84,722,223 (+)Ensembl
GRCm38.p6 Ensembl883,976,883 - 83,995,594 (+)Ensembl
RefSeq Acc Id: NM_001277898   ⟹   NP_001264827
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39884,703,512 - 84,723,073 (+)NCBI
GRCm38883,976,883 - 83,996,444 (+)NCBI
Celera888,266,474 - 88,289,644 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008854   ⟹   NP_032880
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39884,699,607 - 84,723,073 (+)NCBI
GRCm38883,972,978 - 83,996,444 (+)NCBI
MGSCv37886,496,877 - 86,520,344 (+)RGD
Celera888,266,474 - 88,289,644 (+)NCBI
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032880   ⟸   NM_008854
- Peptide Label: isoform 1
- UniProtKB: Q9JID0 (UniProtKB/Swiss-Prot),   P05132 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001264827   ⟸   NM_001277898
- Peptide Label: isoform 2
- UniProtKB: P05132 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000147256   ⟸   ENSMUST00000211558
Ensembl Acc Id: ENSMUSP00000005606   ⟸   ENSMUST00000005606
Protein Domains
AGC-kinase C-terminal   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05132-F1-model_v2 AlphaFold P05132 1-351 view protein structure

Promoters
RGD ID:8667641
Promoter ID:EPDNEW_M11846
Type:initiation region
Name:Prkaca_1
Description:Mus musculus protein kinase, cAMP dependent, catalytic, alpha, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38883,972,982 - 83,973,042EPDNEW
RGD ID:6843631
Promoter ID:MM_KWN:55037
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:NM_008854
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36886,496,176 - 86,496,902 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97592 AgrOrtholog
Ensembl Genes ENSMUSG00000005469 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000005606 ENTREZGENE
  ENSMUST00000005606.8 UniProtKB/Swiss-Prot
  ENSMUST00000211558 ENTREZGENE
  ENSMUST00000211558.2 UniProtKB/Swiss-Prot
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro AGC-kinase_C UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
  STKc_PKA UniProtKB/Swiss-Prot
KEGG Report mmu:18747 UniProtKB/Swiss-Prot
MGD MGI:97592 ENTREZGENE
NCBI Gene 18747 ENTREZGENE
PANTHER CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA UniProtKB/Swiss-Prot
  CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Prkaca PhenoGen
PROSITE AGC_KINASE_CTER UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
SMART S_TK_X UniProtKB/Swiss-Prot
  S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt J9JDU9_MOUSE UniProtKB/TrEMBL
  KAPCA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JID0 ENTREZGENE
UniProt Secondary Q9JID0 UniProtKB/Swiss-Prot