Cdk9 (cyclin dependent kinase 9) - Rat Genome Database

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Gene: Cdk9 (cyclin dependent kinase 9) Mus musculus
Analyze
Symbol: Cdk9
Name: cyclin dependent kinase 9
RGD ID: 1552365
MGI Page MGI
Description: Enables several functions, including RNA polymerase II CTD heptapeptide repeat kinase activity; nucleic acid binding activity; and protein kinase binding activity. Involved in regulation of mRNA 3'-end processing. Located in nucleus. Part of cyclin/CDK positive transcription elongation factor complex. Is expressed in several structures, including alimentary system; early embryo; genitourinary system; hemolymphoid system; and nervous system. Orthologous to human CDK9 (cyclin dependent kinase 9).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cell division protein kinase 9; cyclin dependent kinase 9 (CDC2-related kinase); cyclin-dependent kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); PI; PITALRE
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm18993  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,595,794 - 32,608,098 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,595,796 - 32,603,088 (-)EnsemblGRCm39 Ensembl
GRCm38232,705,782 - 32,712,784 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,705,784 - 32,713,076 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,561,302 - 32,568,304 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,529,447 - 32,534,794 (-)NCBIMGSCv36mm8
Celera232,412,389 - 32,419,391 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alvocidib  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
berberine  (ISO)
bisphenol A  (ISO)
bisphenol F  (EXP)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
Cinobufagin  (ISO)
clofibrate  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP)
cypermethrin  (ISO)
D-glucose  (EXP)
decabromodiphenyl ether  (ISO)
deferasirox  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dimethylarsinic acid  (ISO)
dinaciclib  (ISO)
disodium selenite  (ISO)
divanadium pentaoxide  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
fenofibrate  (ISO)
fenvalerate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
glucose  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (EXP)
lycopene  (ISO)
methamphetamine  (EXP)
nickel dichloride  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
PhIP  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rucaparib  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
sorafenib  (ISO)
streptozocin  (EXP,ISO)
sunitinib  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
wogonin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Genomic organization, promoter analysis, and chromosomal mapping of the mouse gene encoding Cdk9. Bagella L, etal., J Cell Biochem 2000 Apr;78(1):170-8.
2. Novel complexes of cyclin-dependent kinases and a cyclin-like protein from Arabidopsis thaliana with a function unrelated to cell division. Barroco RM, etal., Cell Mol Life Sci 2003 Feb;60(2):401-12.
3. Updating the RNA polymerase CTD code: adding gene-specific layers. Egloff S, etal., Trends Genet. 2012 Jul;28(7):333-41. doi: 10.1016/j.tig.2012.03.007. Epub 2012 May 21.
4. The writers, readers, and functions of the RNA polymerase II C-terminal domain code. Jeronimo C, etal., Chem Rev. 2013 Nov 13;113(11):8491-522. doi: 10.1021/cr4001397. Epub 2013 Jul 10.
5. Control of transcriptional elongation. Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure. Sano M, etal., EMBO J 2004 Sep 1;23(17):3559-69. Epub 2004 Aug 5.
11. Protective effect of berberine on antioxidant enzymes and positive transcription elongation factor b expression in diabetic rat liver. Zhou JY and Zhou SW, Fitoterapia. 2011 Mar;82(2):184-9. doi: 10.1016/j.fitote.2010.08.019. Epub 2010 Sep 7.
Additional References at PubMed
PMID:8889548   PMID:9766517   PMID:9827693   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12037670   PMID:12115727   PMID:12477932   PMID:14610273  
PMID:15489334   PMID:15782199   PMID:16109376   PMID:16141072   PMID:16141073   PMID:16245309   PMID:16484339   PMID:16980611   PMID:17108004   PMID:17459355   PMID:17938200   PMID:18039861  
PMID:18546201   PMID:18641664   PMID:18662700   PMID:18780834   PMID:18799693   PMID:19364821   PMID:19521018   PMID:19575011   PMID:19914168   PMID:20059953   PMID:20081228   PMID:20434984  
PMID:20570862   PMID:20593818   PMID:20665673   PMID:20940258   PMID:21245044   PMID:21267068   PMID:21639898   PMID:21873635   PMID:21896721   PMID:22509028   PMID:22547058   PMID:22767893  
PMID:22922464   PMID:23154982   PMID:23663783   PMID:23732910   PMID:23752591   PMID:23921639   PMID:24194600   PMID:25128497   PMID:25209997   PMID:26764384   PMID:26974661   PMID:27102157  
PMID:27488304   PMID:27626380   PMID:28608935   PMID:28931940   PMID:29170386   PMID:30196744   PMID:30209133   PMID:30487288   PMID:31005255   PMID:31128943   PMID:31257635   PMID:31307784  
PMID:32124532   PMID:32556803   PMID:32731332   PMID:32934219   PMID:33438260   PMID:34161765   PMID:34761662   PMID:35449600   PMID:36082129   PMID:37139431   PMID:38355793   PMID:39235466  


Genomics

Comparative Map Data
Cdk9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,595,794 - 32,608,098 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,595,796 - 32,603,088 (-)EnsemblGRCm39 Ensembl
GRCm38232,705,782 - 32,712,784 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,705,784 - 32,713,076 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,561,302 - 32,568,304 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,529,447 - 32,534,794 (-)NCBIMGSCv36mm8
Celera232,412,389 - 32,419,391 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
CDK9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,786,034 - 127,790,792 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,785,679 - 127,790,792 (+)EnsemblGRCh38hg38GRCh38
GRCh379130,548,313 - 130,553,071 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,588,152 - 129,592,184 (+)NCBINCBI36Build 36hg18NCBI36
Build 349127,627,890 - 127,631,917NCBI
Celera9101,199,168 - 101,203,915 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,164,574 - 100,169,598 (+)NCBIHuRef
CHM1_19130,699,854 - 130,704,602 (+)NCBICHM1_1
T2T-CHM13v2.09139,993,485 - 139,998,243 (+)NCBIT2T-CHM13v2.0
Cdk9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,394,168 - 36,399,016 (-)NCBIGRCr8
mRatBN7.2315,996,467 - 16,001,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,996,468 - 16,002,410 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx319,065,041 - 19,069,877 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,650,044 - 27,654,880 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,901,304 - 25,906,154 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,742,269 - 11,747,117 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,742,266 - 11,747,113 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0317,081,164 - 17,086,012 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,672,861 - 11,677,709 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,569,232 - 11,574,081 (-)NCBI
Celera310,737,357 - 10,742,205 (-)NCBICelera
Cytogenetic Map3p11NCBI
Cdk9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419873,289 - 883,160 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955419874,959 - 883,160 (-)NCBIChiLan1.0ChiLan1.0
CDK9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,558,761 - 11,569,295 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,561,106 - 11,571,580 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,905,468 - 98,909,923 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,580,862 - 127,584,936 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,580,862 - 127,584,935 (+)Ensemblpanpan1.1panPan2
CDK9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,615,271 - 55,619,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,615,827 - 55,620,236 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,808,829 - 54,812,940 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,536,951 - 56,541,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,536,954 - 56,541,348 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,296,987 - 55,301,098 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,611,719 - 55,615,827 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,703,144 - 55,707,256 (-)NCBIUU_Cfam_GSD_1.0
Cdk9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,678,357 - 195,682,223 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,446,858 - 15,452,796 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,446,864 - 15,450,750 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,276,841 - 268,281,052 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,277,083 - 268,280,493 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,142,973 - 302,146,162 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,342,240 - 10,346,792 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,342,801 - 10,346,502 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,874,123 - 5,879,334 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247607,760,474 - 7,765,711 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdk9
564 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1939
Count of miRNA genes:649
Interacting mature miRNAs:842
Transcripts:ENSMUST00000009699, ENSMUST00000120105, ENSMUST00000123170, ENSMUST00000125058, ENSMUST00000128265, ENSMUST00000130399, ENSMUST00000144210, ENSMUST00000154131, ENSMUST00000155205
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552706Cia24_mcollagen induced arthritis QTL 24 (mouse)Not determined22467911533523172Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
8552705Cia25_mcollagen induced arthritis 25 (mouse)Not determined22467911533523172Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23120303544508204Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse

Markers in Region
AW821975  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
Whitehead/MRC_RH42030.06UniSTS
Cdk9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384156,214,173 - 156,215,006UniSTSGRCm38
MGSCv374155,588,282 - 155,589,115UniSTSGRCm37
Celera4158,470,643 - 158,471,476UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map4E2UniSTS
cM Map2 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000009699   ⟹   ENSMUSP00000009699
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,597,450 - 32,602,796 (-)Ensembl
GRCm38.p6 Ensembl232,707,438 - 32,712,784 (-)Ensembl
Ensembl Acc Id: ENSMUST00000120105   ⟹   ENSMUSP00000113327
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,597,456 - 32,602,279 (-)Ensembl
GRCm38.p6 Ensembl232,707,444 - 32,712,267 (-)Ensembl
Ensembl Acc Id: ENSMUST00000123170   ⟹   ENSMUSP00000115318
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,597,861 - 32,603,088 (-)Ensembl
GRCm38.p6 Ensembl232,707,849 - 32,713,076 (-)Ensembl
Ensembl Acc Id: ENSMUST00000125058
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,595,796 - 32,601,059 (-)Ensembl
GRCm38.p6 Ensembl232,705,784 - 32,711,047 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,599,668 - 32,600,514 (-)Ensembl
GRCm38.p6 Ensembl232,709,656 - 32,710,502 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130399
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,598,113 - 32,599,733 (-)Ensembl
GRCm38.p6 Ensembl232,708,101 - 32,709,721 (-)Ensembl
Ensembl Acc Id: ENSMUST00000144210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,599,544 - 32,600,361 (-)Ensembl
GRCm38.p6 Ensembl232,709,532 - 32,710,349 (-)Ensembl
Ensembl Acc Id: ENSMUST00000154131   ⟹   ENSMUSP00000120857
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,599,868 - 32,602,769 (-)Ensembl
GRCm38.p6 Ensembl232,709,856 - 32,712,757 (-)Ensembl
Ensembl Acc Id: ENSMUST00000155205   ⟹   ENSMUSP00000115299
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl232,600,170 - 32,602,265 (-)Ensembl
GRCm38.p6 Ensembl232,710,158 - 32,712,253 (-)Ensembl
RefSeq Acc Id: NM_130860   ⟹   NP_570930
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39232,595,794 - 32,602,796 (-)NCBI
GRCm38232,705,782 - 32,712,784 (-)ENTREZGENE
MGSCv37232,561,302 - 32,568,304 (-)RGD
Celera232,412,389 - 32,419,391 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011239001   ⟹   XP_011237303
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39232,597,450 - 32,608,098 (-)NCBI
GRCm38232,707,438 - 32,712,757 (-)NCBI
Sequence:
RefSeq Acc Id: NP_570930   ⟸   NM_130860
- UniProtKB: Q99J95 (UniProtKB/Swiss-Prot),   Q8BTN0 (UniProtKB/Swiss-Prot),   Q3UQI6 (UniProtKB/Swiss-Prot),   Q3UPT3 (UniProtKB/Swiss-Prot),   B0R020 (UniProtKB/Swiss-Prot),   Q3UMY2 (UniProtKB/Swiss-Prot),   Q3U002 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011237303   ⟸   XM_011239001
- Peptide Label: isoform X1
- UniProtKB: Q99J95 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000009699   ⟸   ENSMUST00000009699
Ensembl Acc Id: ENSMUSP00000120857   ⟸   ENSMUST00000154131
Ensembl Acc Id: ENSMUSP00000113327   ⟸   ENSMUST00000120105
Ensembl Acc Id: ENSMUSP00000115318   ⟸   ENSMUST00000123170
Ensembl Acc Id: ENSMUSP00000115299   ⟸   ENSMUST00000155205
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99J95-F1-model_v2 AlphaFold Q99J95 1-372 view protein structure

Promoters
RGD ID:6831003
Promoter ID:MM_KWN:28749
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney,   Lung,   MEF_B6
Transcripts:OTTMUST00000029811,   OTTMUST00000029813,   OTTMUST00000029814,   OTTMUST00000029815
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36232,565,066 - 32,567,417 (-)MPROMDB
RGD ID:6831004
Promoter ID:MM_KWN:28750
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000120105,   OTTMUST00000029809,   OTTMUST00000029810,   OTTMUST00000075916,   UC008JGO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36232,567,916 - 32,569,167 (-)MPROMDB
RGD ID:6877034
Promoter ID:EPDNEW_M1968
Type:initiation region
Name:Cdk9_1
Description:Mus musculus cyclin-dependent kinase 9 (CDC2-related kinase), mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38232,712,763 - 32,712,823EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1328368 AgrOrtholog
Ensembl Genes ENSMUSG00000009555 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000009699 ENTREZGENE
  ENSMUST00000009699.16 UniProtKB/Swiss-Prot
  ENSMUST00000120105.8 UniProtKB/Swiss-Prot
  ENSMUST00000123170.8 UniProtKB/TrEMBL
  ENSMUST00000154131.2 UniProtKB/TrEMBL
  ENSMUST00000155205.2 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro CDK UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report mmu:107951 UniProtKB/Swiss-Prot
MGD MGI:1328368 ENTREZGENE
NCBI Gene Cdk9 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/Swiss-Prot
  CYCLIN-DEPENDENT KINASE 9 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cdk9 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B0R020 ENTREZGENE
  B0R021_MOUSE UniProtKB/TrEMBL
  CDK9_MOUSE UniProtKB/Swiss-Prot
  D6RGN3_MOUSE UniProtKB/TrEMBL
  D6RHP4_MOUSE UniProtKB/TrEMBL
  Q3U002 ENTREZGENE
  Q3UMY2 ENTREZGENE
  Q3UPT3 ENTREZGENE
  Q3UQI6 ENTREZGENE
  Q8BTN0 ENTREZGENE
  Q99J95 ENTREZGENE
UniProt Secondary B0R020 UniProtKB/Swiss-Prot
  Q3U002 UniProtKB/Swiss-Prot
  Q3UMY2 UniProtKB/Swiss-Prot
  Q3UPT3 UniProtKB/Swiss-Prot
  Q3UQI6 UniProtKB/Swiss-Prot
  Q8BTN0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Cdk9  cyclin dependent kinase 9  Cdk9  cyclin-dependent kinase 9 (CDC2-related kinase)  Symbol and/or name change 5135510 APPROVED
2024-08-21 Cdk9  cyclin-dependent kinase 9 (CDC2-related kinase)  Cdk9  cyclin dependent kinase 9  Symbol and/or name change 5135510 APPROVED
2023-06-27 Cdk9  cyclin dependent kinase 9  Cdk9  cyclin dependent kinase 9 (CDC2-related kinase)  Symbol and/or name change 5135510 APPROVED
2023-05-02 Cdk9  cyclin dependent kinase 9 (CDC2-related kinase)  Cdk9  cyclin-dependent kinase 9 (CDC2-related kinase)  Symbol and/or name change 5135510 APPROVED