Axin1 (axin 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Axin1 (axin 1) Mus musculus
Analyze
Symbol: Axin1
Name: axin 1
RGD ID: 1552250
MGI Page MGI
Description: Enables several functions, including SMAD binding activity; beta-catenin binding activity; and enzyme binding activity. Involved in positive regulation of JNK cascade and positive regulation of protein phosphorylation. Acts upstream of or within several processes, including chordate embryonic development; regulation of macromolecule metabolic process; and regulation of signal transduction. Located in several cellular components, including cell cortex; cytoplasmic vesicle; and microtubule cytoskeleton. Part of Wnt signalosome and beta-catenin destruction complex. Is expressed in several structures, including eye; forebrain; genitourinary system; hemolymphoid system gland; and jaw. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and urinary bladder cancer. Orthologous to human AXIN1 (axin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI316800; Axin; axin-1; axis inhibition protein 1; Fu; fused; Kb; Ki; kinky; knobbly; MGC132911
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,350,294 - 26,414,784 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,357,662 - 26,414,785 (+)EnsemblGRCm39 Ensembl
GRCm381726,131,217 - 26,195,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,138,688 - 26,195,811 (+)EnsemblGRCm38mm10GRCm38
MGSCv371726,275,631 - 26,332,756 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,866,334 - 25,923,411 (+)NCBIMGSCv36mm8
Celera1726,676,271 - 26,729,569 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-methylcholine  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-fluorouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
AH23848  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
choline  (EXP)
cisplatin  (ISO)
clothianidin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
curcumin  (ISO)
cyanocob(III)alamin  (EXP)
cyclosporin A  (ISO)
diazinon  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (EXP)
ethosuximide  (ISO)
fenthion  (EXP)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
FR900359  (ISO)
gentamycin  (ISO)
glycine betaine  (EXP)
lithocholic acid  (EXP)
methidathion  (EXP)
monosodium L-glutamate  (EXP)
N-methyl-N-nitrosourea  (ISO)
NMN zwitterion  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
platycodin D  (EXP)
progesterone  (EXP,ISO)
quercetin  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
titanium dioxide  (EXP)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of protein kinase activity  (ISO)
adult walking behavior  (IMP)
apoptotic process  (IEA)
axial mesoderm development  (IMP)
axial mesoderm formation  (IMP)
beta-catenin destruction complex assembly  (ISO)
canonical Wnt signaling pathway  (IDA,IMP)
cell development  (IBA)
cytoplasmic microtubule organization  (IGI)
dorsal/ventral axis specification  (IDA,ISO)
dorsal/ventral pattern formation  (IMP,ISO)
embryonic skeletal joint morphogenesis  (IMP)
epigenetic programming in the zygotic pronuclei  (IMP)
erythrocyte homeostasis  (IMP)
head development  (IMP)
hemoglobin metabolic process  (IMP)
in utero embryonic development  (IGI,IMP)
negative regulation of canonical Wnt signaling pathway  (IBA,IDA,ISO)
negative regulation of fat cell differentiation  (IDA)
negative regulation of gene expression  (IDA)
negative regulation of protein metabolic process  (IDA)
negative regulation of transcription elongation by RNA polymerase II  (IDA)
negative regulation of Wnt signaling pathway  (IDA)
nervous system process  (IMP)
nucleocytoplasmic transport  (IDA)
positive regulation of JNK cascade  (IMP)
positive regulation of JUN kinase activity  (IDA,IMP,ISO)
positive regulation of peptidyl-serine phosphorylation  (IDA)
positive regulation of peptidyl-threonine phosphorylation  (IDA)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (IBA,IDA)
positive regulation of protein catabolic process  (ISO)
positive regulation of protein kinase activity  (IDA,ISO)
positive regulation of protein phosphorylation  (IDA,ISO)
positive regulation of protein ubiquitination  (IDA,IGI,IMP,ISO)
positive regulation of transforming growth factor beta receptor signaling pathway  (IDA,IGI,IMP)
positive regulation of ubiquitin-dependent protein catabolic process  (IDA,ISO)
post-anal tail morphogenesis  (IMP)
proteasome-mediated ubiquitin-dependent protein catabolic process  (NAS)
protein catabolic process  (IDA)
protein polyubiquitination  (IDA)
protein-containing complex assembly  (IEA,ISO)
regulation of canonical Wnt signaling pathway  (IDA)
regulation of protein phosphorylation  (IGI)
response to quercetin  (ISO)
sensory perception of sound  (IMP)
Wnt signaling pathway  (IDA,IPI)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal allantois morphology  (IAGP)
abnormal amniotic cavity morphology  (IAGP)
abnormal axial mesoderm morphology  (IAGP)
abnormal axial skeleton morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal caudal vertebrae morphology  (IAGP)
abnormal cephalic neural fold morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal developmental patterning  (IEA)
abnormal ectoderm development  (IEA)
abnormal embryo development  (IAGP)
abnormal embryo turning  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal facial morphology  (IAGP)
abnormal head morphology  (IAGP)
abnormal hindlimb morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal lumbar vertebrae morphology  (IEA)
abnormal nose morphology  (IAGP)
abnormal sacral vertebrae morphology  (IEA)
abnormal tail length  (IAGP)
abnormal tail morphology  (IAGP)
abnormal thoracic vertebrae morphology  (IEA)
abnormal vertebrae morphology  (IAGP)
absent forebrain  (IAGP)
absent kidney  (IAGP)
absent ribs  (IAGP)
absent ureter  (IAGP)
bifurcated tail  (IAGP)
cardia bifida  (IAGP)
caudal vertebral fusion  (IEA)
circling  (IAGP)
cleft palate  (IAGP)
deafness  (IAGP)
decreased body length  (IAGP)
decreased caudal vertebrae number  (IAGP)
decreased embryo size  (IAGP)
disorganized embryonic tissue  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enlarged pericardium  (IAGP)
flat head  (IAGP)
forebrain hypoplasia  (IAGP)
genetic imprinting  (IAGP)
impaired spacing of implantation sites  (IEA)
incomplete rostral neuropore closure  (IAGP)
kinked neural tube  (IAGP)
kinked tail  (IEA)
lumbar vertebral fusion  (IEA)
maternal effect  (IAGP)
maternal imprinting  (IAGP)
no abnormal phenotype detected  (IAGP)
paternal imprinting  (IAGP)
prenatal lethality  (IEA)
rectal atresia  (IAGP)
reversion by viral sequence excision  (IAGP)
rib fusion  (IAGP)
rostral-caudal axis duplication  (IAGP)
sacral vertebral fusion  (IEA)
short tail  (IAGP)
shortened head  (IAGP)
small amniotic cavity  (IEA)
small tail bud  (IAGP)
split notochord  (IAGP)
thoracic vertebral fusion  (IEA)
twin decidual capsule  (IEA)
urethra atresia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Quercetin Confers Tumoricidal Activity Through Multipathway Mechanisms in A N-Methylnitrosourea Rat Model of Colon Cancer Ahmed HH, etal., Asian Pac J Cancer Prev. 2016 Nov 1;17(11):4991-4998. doi: 10.22034/APJCP.2016.17.11.4991.
2. Insights from studies with oral cleft genes suggest associations between WNT-pathway genes and risk of oral cancer. Andrade Filho PA, etal., J Dent Res. 2011 Jun;90(6):740-6. doi: 10.1177/0022034511401622. Epub 2011 Mar 10.
3. Conditional disruption of Axin1 leads to development of liver tumors in mice. Feng GJ, etal., Gastroenterology. 2012 Dec;143(6):1650-9. doi: 10.1053/j.gastro.2012.08.047. Epub 2012 Sep 6.
4. X-radiation induces non-small-cell lung cancer apoptosis by upregulation of Axin expression. Han Y, etal., Int J Radiat Oncol Biol Phys. 2009 Oct 1;75(2):518-26. doi: 10.1016/j.ijrobp.2009.05.040.
5. Genetic polymorphisms in the Wnt/β-catenin pathway genes as predictors of tumor development and survival in patients with hepatitis B virus-associated hepatocellular carcinoma. Kim SS, etal., Clin Biochem. 2016 Jul;49(10-11):792-801. doi: 10.1016/j.clinbiochem.2016.01.025. Epub 2016 Mar 9.
6. Wnt signalling and its impact on development and cancer. Klaus A and Birchmeier W, Nat Rev Cancer. 2008 May;8(5):387-98.
7. Chinese Herbal Formulas Miao-Yi-Ai-Tang Inhibits the Proliferation and Migration of Lung Cancer Cells through Targeting β-Catenin/AXIN and Presents Synergistic Effect with Cisplatin Suppressing Lung Cancer. Li B, etal., Biomed Res Int. 2020 Jan 16;2020:2761850. doi: 10.1155/2020/2761850. eCollection 2020.
8. Association between AXIN1 Gene Polymorphisms and Bladder Cancer in Chinese Han Population. Li Q, etal., Dis Markers. 2019 Apr 15;2019:3949343. doi: 10.1155/2019/3949343. eCollection 2019.
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. MGD IEA MGD IEA
11. Reduced expression of Axin correlates with tumour progression of oesophageal squamous cell carcinoma. Nakajima M, etal., Br J Cancer. 2003 Jun 2;88(11):1734-9. doi: 10.1038/sj.bjc.6600941.
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
15. Mouse MP Annotation Import Pipeline RGD automated import pipeline
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Satoh S, etal., Nat Genet 2000 Mar;24(3):245-50.
19. MicroRNA-1181 supports the growth of hepatocellular carcinoma by repressing AXIN1. Song Z, etal., Biomed Pharmacother. 2019 Nov;119:109397. doi: 10.1016/j.biopha.2019.109397. Epub 2019 Sep 9.
20. Disabled-2 and Axin are concurrently colocalized and underexpressed in lung cancers. Xu HT, etal., Hum Pathol. 2011 Oct;42(10):1491-8. doi: 10.1016/j.humpath.2011.01.004. Epub 2011 Apr 14.
21. Axin gene methylation status correlates with radiosensitivity of lung cancer cells. Yang LH, etal., BMC Cancer. 2013 Aug 2;13:368. doi: 10.1186/1471-2407-13-368.
22. Abnormal hypermethylation and clinicopathological significance of Axin gene in lung cancer. Yang LH, etal., Tumour Biol. 2013 Apr;34(2):749-57. doi: 10.1007/s13277-012-0604-z. Epub 2012 Nov 29.
23. Frequent genetic alterations and reduced expression of the Axin1 gene in oral squamous cell carcinoma: involvement in tumor progression and metastasis. Zhou CX and Gao Y, Oncol Rep. 2007 Jan;17(1):73-9.
Additional References at PubMed
PMID:924142   PMID:1350556   PMID:2090373   PMID:5031320   PMID:5940872   PMID:6547105   PMID:6816725   PMID:7276510   PMID:7579885   PMID:7829069   PMID:7894168   PMID:8082835  
PMID:8405974   PMID:8536979   PMID:8889548   PMID:9230313   PMID:9335612   PMID:9601641   PMID:9891778   PMID:9920888   PMID:10318824   PMID:10330403   PMID:10575011   PMID:10581160  
PMID:10688669   PMID:10922068   PMID:10937998   PMID:11113207   PMID:11132407   PMID:11170344   PMID:11336703   PMID:11557983   PMID:11703504   PMID:11739413   PMID:11812828   PMID:11829488  
PMID:11884395   PMID:11955436   PMID:12138115   PMID:12223491   PMID:12421363   PMID:12477932   PMID:12520002   PMID:12569091   PMID:12601169   PMID:12702649   PMID:12717450   PMID:12805222  
PMID:12878610   PMID:12897152   PMID:13340237   PMID:14379171   PMID:14610273   PMID:14664817   PMID:14723853   PMID:14734535   PMID:14966280   PMID:14981260   PMID:15042511   PMID:15057752  
PMID:15067197   PMID:15226823   PMID:15327768   PMID:15526030   PMID:15579909   PMID:15820042   PMID:15899843   PMID:16055716   PMID:16055717   PMID:16141072   PMID:16378759   PMID:16510873  
PMID:16577797   PMID:16601693   PMID:16602821   PMID:16815997   PMID:16868943   PMID:17053159   PMID:17246824   PMID:17247577   PMID:17681137   PMID:17720811   PMID:17934337   PMID:18076571  
PMID:18077588   PMID:18083923   PMID:18113441   PMID:18316368   PMID:18583422   PMID:18606656   PMID:18632848   PMID:18786926   PMID:18951693   PMID:19075000   PMID:19107203   PMID:19141611  
PMID:19204372   PMID:19299626   PMID:19331826   PMID:19515997   PMID:19576224   PMID:19581931   PMID:19623616   PMID:19731416   PMID:19759537   PMID:19828779   PMID:20368287   PMID:20409609  
PMID:20436479   PMID:20531388   PMID:20650886   PMID:20883684   PMID:21003499   PMID:21057547   PMID:21242974   PMID:21267068   PMID:21344612   PMID:21520248   PMID:21652647   PMID:21677750  
PMID:21873635   PMID:21940452   PMID:22071115   PMID:22307604   PMID:22473005   PMID:22509369   PMID:22682247   PMID:22899650   PMID:22933777   PMID:23293290   PMID:23535572   PMID:23959799  
PMID:23972596   PMID:24093678   PMID:24265074   PMID:24525297   PMID:24948604   PMID:24952082   PMID:24952961   PMID:24976009   PMID:25002183   PMID:25331900   PMID:25336178   PMID:25866367  
PMID:25873176   PMID:26204446   PMID:26582204   PMID:26586428   PMID:27284927   PMID:27601169   PMID:27732831   PMID:28723898   PMID:29475039   PMID:29525529   PMID:30037926   PMID:30070692  
PMID:30537735   PMID:30550785   PMID:30737831   PMID:30954225   PMID:31073336   PMID:31846370   PMID:32167488   PMID:32253237   PMID:33913171   PMID:34032268   PMID:34127677   PMID:34150743  
PMID:36217034   PMID:36308071   PMID:36356835   PMID:36541713   PMID:37201672   PMID:38010886   PMID:38363556   PMID:38898113  


Genomics

Comparative Map Data
Axin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,350,294 - 26,414,784 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,357,662 - 26,414,785 (+)EnsemblGRCm39 Ensembl
GRCm381726,131,217 - 26,195,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,138,688 - 26,195,811 (+)EnsemblGRCm38mm10GRCm38
MGSCv371726,275,631 - 26,332,756 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,866,334 - 25,923,411 (+)NCBIMGSCv36mm8
Celera1726,676,271 - 26,729,569 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.07NCBI
AXIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816287,440 - 352,723 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16287,440 - 352,723 (-)EnsemblGRCh38hg38GRCh38
GRCh3716337,440 - 402,723 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616277,441 - 342,465 (-)NCBINCBI36Build 36hg18NCBI36
Build 3416277,440 - 342,465NCBI
Celera16537,339 - 602,420 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16255,743 - 344,360 (-)NCBIHuRef
CHM1_116337,402 - 402,637 (-)NCBICHM1_1
T2T-CHM13v2.016282,313 - 347,596 (-)NCBIT2T-CHM13v2.0
Axin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,667,894 - 15,720,092 (+)NCBIGRCr8
mRatBN7.21015,163,477 - 15,215,615 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,163,684 - 15,215,615 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,903,082 - 19,955,387 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,391,961 - 19,444,266 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,891,384 - 14,943,546 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_5.01015,324,330 - 15,376,252 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,409,373 - 15,462,726 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,410,421 - 15,463,774 (+)NCBI
Celera1014,831,660 - 14,883,421 (+)NCBICelera
Cytogenetic Map10q12NCBI
Axin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,843,152 - 16,898,430 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,845,728 - 16,898,301 (+)NCBIChiLan1.0ChiLan1.0
AXIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218506,910 - 581,764 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,299,164 - 4,372,528 (-)NCBINHGRI_mPanPan1
PanPan1.116278,239 - 337,891 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16278,239 - 337,891 (-)Ensemblpanpan1.1panPan2
AXIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,155,797 - 40,218,330 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,158,244 - 40,218,343 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,419,076 - 41,481,969 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,497,801 - 40,560,709 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,500,504 - 40,560,706 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1640,186,114 - 40,248,973 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0640,146,325 - 40,210,047 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,625,599 - 40,688,493 (+)NCBIUU_Cfam_GSD_1.0
Axin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,502,114 - 112,535,977 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501599,919 - 633,873 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501599,963 - 633,837 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AXIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,337,071 - 41,393,997 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,344,908 - 41,393,999 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,033,961 - 41,085,857 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AXIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15233,520 - 295,134 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5234,060 - 290,575 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,878,427 - 30,943,289 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Axin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,139,165 - 1,195,230 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,139,165 - 1,195,477 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Axin1
2558 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:875
Count of miRNA genes:444
Interacting mature miRNAs:517
Transcripts:ENSMUST00000074370, ENSMUST00000118904, ENSMUST00000163421, ENSMUST00000168282, ENSMUST00000169268
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171263668226401133Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171683545533819843Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17787584329487423Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
12903990Opfaq5_mopen field activity QTL 5 (mouse)172595092528992098Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse

Markers in Region
RH136120  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,195,417 - 26,195,609UniSTSGRCm38
MGSCv371726,332,362 - 26,332,554UniSTSGRCm37
Celera1726,729,175 - 26,729,367UniSTS
Cytogenetic Map17A3.3UniSTS
AF009011  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,195,318 - 26,195,439UniSTSGRCm38
MGSCv371726,332,263 - 26,332,384UniSTSGRCm37
Celera1726,729,076 - 26,729,197UniSTS
Cytogenetic Map17A3.3UniSTS
Whitehead/MRC_RH17328.72UniSTS
AI661267  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,196,038 - 26,196,269UniSTSGRCm38
MGSCv371726,332,983 - 26,333,214UniSTSGRCm37
Celera1726,729,796 - 26,730,027UniSTS
Cytogenetic Map17A3.3UniSTS
Whitehead/MRC_RH17328.92UniSTS
PMC134648P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,142,685 - 26,143,342UniSTSGRCm38
MGSCv371726,279,630 - 26,280,287UniSTSGRCm37
Celera1726,676,339 - 26,676,996UniSTS
Cytogenetic Map17A3.3UniSTS
D17Mit100  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,182,038 - 26,182,159UniSTSGRCm38
MGSCv371726,318,983 - 26,319,104UniSTSGRCm37
Celera1726,715,771 - 26,715,896UniSTS
Cytogenetic Map17A3.3UniSTS
cM Map1711.75UniSTS
Whitehead Genetic173.3UniSTS
Whitehead/MRC_RH17328.82UniSTS
Whitehead_YAC17 UniSTS
Axin1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A3.3UniSTS
cM Map1711.8UniSTS
RH44784  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381726,195,673 - 26,195,786UniSTSGRCm38
MGSCv371726,332,618 - 26,332,731UniSTSGRCm37
Celera1726,729,431 - 26,729,544UniSTS
Cytogenetic Map17A3.3UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001159598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001394389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA259709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF009011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW061082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC113171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG803725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ060582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU019610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000074370   ⟹   ENSMUSP00000073974
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1726,357,662 - 26,414,785 (+)Ensembl
GRCm38.p6 Ensembl1726,138,688 - 26,195,811 (+)Ensembl
Ensembl Acc Id: ENSMUST00000118904   ⟹   ENSMUSP00000113756
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1726,357,802 - 26,414,215 (+)Ensembl
GRCm38.p6 Ensembl1726,138,828 - 26,195,241 (+)Ensembl
Ensembl Acc Id: ENSMUST00000163421   ⟹   ENSMUSP00000132000
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1726,361,592 - 26,409,205 (+)Ensembl
GRCm38.p6 Ensembl1726,138,950 - 26,195,294 (+)Ensembl
Ensembl Acc Id: ENSMUST00000168282   ⟹   ENSMUSP00000127182
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1726,362,321 - 26,403,288 (+)Ensembl
GRCm38.p6 Ensembl1726,143,347 - 26,184,314 (+)Ensembl
Ensembl Acc Id: ENSMUST00000169268
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1726,407,127 - 26,407,769 (+)Ensembl
GRCm38.p6 Ensembl1726,188,153 - 26,188,795 (+)Ensembl
Ensembl Acc Id: ENSMUST00020183805   ⟹   ENSMUSP00001091662
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1726,357,924 - 26,414,268 (+)Ensembl
RefSeq Acc Id: NM_001159598   ⟹   NP_001153070
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391726,357,662 - 26,414,784 (+)NCBI
GRCm381726,138,686 - 26,195,811 (+)NCBI
MGSCv371726,275,631 - 26,332,756 (+)RGD
Celera1726,676,271 - 26,729,569 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001394381   ⟹   NP_001381310
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391726,350,294 - 26,414,784 (+)NCBI
RefSeq Acc Id: NM_001394382   ⟹   NP_001381311
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391726,350,294 - 26,414,784 (+)NCBI
RefSeq Acc Id: NM_001394389   ⟹   NP_001381318
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391726,350,294 - 26,414,784 (+)NCBI
RefSeq Acc Id: NM_009733   ⟹   NP_033863
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391726,357,662 - 26,414,784 (+)NCBI
GRCm381726,138,686 - 26,195,811 (+)NCBI
MGSCv371726,275,631 - 26,332,756 (+)RGD
Celera1726,676,271 - 26,729,569 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523516   ⟹   XP_006523579
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391726,357,669 - 26,414,784 (+)NCBI
GRCm381726,138,958 - 26,195,810 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033863   ⟸   NM_009733
- Peptide Label: isoform 2
- UniProtKB: O35625 (UniProtKB/Swiss-Prot),   E9QMJ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001153070   ⟸   NM_001159598
- Peptide Label: isoform 1
- UniProtKB: Q14DJ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523579   ⟸   XM_006523516
- Peptide Label: isoform X3
- UniProtKB: Q7TMI9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000132000   ⟸   ENSMUST00000163421
Ensembl Acc Id: ENSMUSP00000113756   ⟸   ENSMUST00000118904
Ensembl Acc Id: ENSMUSP00000073974   ⟸   ENSMUST00000074370
Ensembl Acc Id: ENSMUSP00000127182   ⟸   ENSMUST00000168282
Ensembl Acc Id: ENSMUSP00001091662   ⟸   ENSMUST00020183805
RefSeq Acc Id: NP_001381310   ⟸   NM_001394381
- Peptide Label: isoform 2
- UniProtKB: O35625 (UniProtKB/Swiss-Prot),   E9QMJ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001381311   ⟸   NM_001394382
- Peptide Label: isoform 1
- UniProtKB: Q14DJ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001381318   ⟸   NM_001394389
- Peptide Label: isoform 1
- UniProtKB: Q14DJ8 (UniProtKB/TrEMBL)
Protein Domains
DIX   RGS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35625-F1-model_v2 AlphaFold O35625 1-863 view protein structure

Promoters
RGD ID:13675226
Promoter ID:EPDNEW_M21762
Type:initiation region
Name:Axin1_1
Description:Mus musculus axin 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381726,138,733 - 26,138,793EPDNEW
RGD ID:6827845
Promoter ID:MM_KWN:22675
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001159598,   OTTMUST00000065524
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361726,275,271 - 26,276,007 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1096327 AgrOrtholog
Ensembl Genes ENSMUSG00000024182 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074370 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000074370.11 UniProtKB/Swiss-Prot
  ENSMUST00000163421.9 UniProtKB/TrEMBL
  ENSMUST00020183805 ENTREZGENE
  ENSMUST00020183805.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.167.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.40.240.130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Axin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Axin_b-cat-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Axin_TNKS-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12005 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1096327 ENTREZGENE
NCBI Gene 12005 ENTREZGENE
PANTHER PTHR46102 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR46102:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AXIN1_TNKS_BD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Axin_b-cat_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Axin1 PhenoGen
PRINTS RGSPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DAX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AXIN1_MOUSE UniProtKB/Swiss-Prot
  E9QMJ8 ENTREZGENE, UniProtKB/TrEMBL
  F6XWC2_MOUSE UniProtKB/TrEMBL
  O35625 ENTREZGENE
  Q14DJ8 ENTREZGENE, UniProtKB/TrEMBL
  Q6IS36_MOUSE UniProtKB/TrEMBL
  Q7TMI9 ENTREZGENE, UniProtKB/TrEMBL