Ihh (Indian hedgehog) - Rat Genome Database

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Gene: Ihh (Indian hedgehog) Mus musculus
Analyze
Symbol: Ihh
Name: Indian hedgehog
RGD ID: 1552237
MGI Page MGI
Description: Enables patched binding activity. Involved in several processes, including endochondral bone morphogenesis; heart looping; and regulation of T cell differentiation. Acts upstream of or within several processes, including camera-type eye development; skeletal system development; and tube morphogenesis. Located in extracellular matrix. Is expressed in several structures, including alimentary system; genitourinary system; limb; retina; and skeleton. Used to study Hirschsprung's disease; annular pancreas; and brachydactyly type A1. Human ortholog(s) of this gene implicated in acrocapitofemoral dysplasia; brachydactyly type A1; retinopathy of prematurity; and syndactyly type 1. Orthologous to human IHH (Indian hedgehog signaling molecule).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HHG-2; indian hedgehog protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,984,474 - 74,990,831 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,984,474 - 74,990,831 (-)EnsemblGRCm39 Ensembl
GRCm38174,945,315 - 74,951,672 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,945,315 - 74,951,672 (-)EnsemblGRCm38mm10GRCm38
MGSCv37174,991,892 - 74,998,225 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,878,525 - 74,884,858 (-)NCBIMGSCv36mm8
Celera175,500,289 - 75,506,631 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
(2,4,5-trichlorophenoxy)acetic acid  (EXP)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (EXP,ISO)
aldrin  (EXP)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP)
Azoxymethane  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP)
Bisphenol B  (EXP)
bromobenzene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
CHIR 99021  (ISO)
chloroethene  (EXP)
choline  (EXP)
chromium(6+)  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (EXP)
corn oil  (EXP)
deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (EXP)
dichloroacetic acid  (EXP)
diethylstilbestrol  (ISO)
diuron  (ISO)
endosulfan  (ISO)
fipronil  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
genistein  (EXP)
glycidol  (ISO)
itraconazole  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (EXP)
L-methionine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
methotrexate  (EXP)
Monobutylphthalate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nevirapine  (EXP)
nicotine  (ISO)
ochratoxin A  (ISO)
orphenadrine  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
phenytoin  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP,ISO)
Ptaquiloside  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
succimer  (EXP)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
theophylline  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
tributylstannane  (EXP)
trichloroethene  (EXP,ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
bone resorption  (IDA)
branching involved in blood vessel morphogenesis  (IMP)
camera-type eye development  (IMP)
camera-type eye photoreceptor cell fate commitment  (IMP)
cartilage development  (IMP,ISO)
cell fate specification  (IBA,IMP)
cell maturation  (IMP)
cell population proliferation  (IMP)
cell-cell signaling  (IEA)
chondrocyte differentiation  (IDA,IMP)
chondrocyte differentiation involved in endochondral bone morphogenesis  (IMP)
chondrocyte proliferation  (IMP)
embryonic camera-type eye morphogenesis  (IMP)
embryonic digestive tract morphogenesis  (IMP)
embryonic digit morphogenesis  (IGI,IMP,ISO)
embryonic pattern specification  (IMP)
embryonic skeletal joint development  (IMP)
endochondral bone morphogenesis  (IMP)
epithelial cell morphogenesis  (IMP)
epithelial cell-cell adhesion  (IMP)
head morphogenesis  (IMP)
heart looping  (IMP)
in utero embryonic development  (IMP)
intein-mediated protein splicing  (IEA)
liver regeneration  (IEA,ISO)
maternal process involved in female pregnancy  (IEA,ISO)
morphogenesis of a branching structure  (IMP)
multicellular organism growth  (IMP)
negative regulation of alpha-beta T cell differentiation  (IMP)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of chondrocyte differentiation  (IMP)
negative regulation of eye pigmentation  (IMP)
negative regulation of immature T cell proliferation in thymus  (IMP)
negative regulation of T cell differentiation in thymus  (IMP)
neuron development  (IMP)
ossification  (IMP)
osteoblast differentiation  (IDA,IGI,IMP)
pancreas development  (IGI,IMP)
pattern specification process  (IMP)
positive regulation of alpha-beta T cell differentiation  (IMP)
positive regulation of cell population proliferation  (IGI,IMP)
positive regulation of collagen biosynthetic process  (IDA)
positive regulation of epithelial cell proliferation  (IEA,ISO)
positive regulation of mesenchymal cell proliferation  (IMP)
positive regulation of smoothened signaling pathway  (ISO,ISS)
positive regulation of T cell differentiation in thymus  (IMP)
positive regulation of transcription by RNA polymerase II  (IGI,IMP)
protein autoprocessing  (IEA)
proteoglycan metabolic process  (IGI)
regulation of gene expression  (IBA)
regulation of growth  (IGI)
response to estradiol  (IEA,ISO)
response to mechanical stimulus  (IEA,ISO)
retinal pigment epithelium development  (IMP)
self proteolysis  (ISS)
skeletal system development  (IMP,ISO)
smooth muscle tissue development  (IMP)
smoothened signaling pathway  (IBA,IDA,IGI,IMP,ISO)
somite development  (IMP)
vasculature development  (IMP)
vitelline membrane formation  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal appendicular skeleton morphology  (IAGP)
abnormal axial skeleton morphology  (IAGP)
abnormal basicranium morphology  (IAGP)
abnormal bone marrow cavity morphology  (IAGP)
abnormal bone mineralization  (IAGP)
abnormal bone ossification  (IAGP)
abnormal bone structure  (IAGP)
abnormal cartilage development  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal chondrocyte differentiation  (IAGP)
abnormal digestive organ placement  (IAGP)
abnormal digestive system morphology  (IAGP)
abnormal digit development  (IAGP)
abnormal digit morphology  (IAGP)
abnormal duodenum morphology  (IAGP)
abnormal humerus morphology  (IAGP)
abnormal joint morphology  (IAGP)
abnormal long bone diaphysis morphology  (IAGP)
abnormal long bone epiphyseal plate morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal long bone hypertrophic chondrocyte zone  (IAGP)
abnormal long bone morphology  (IAGP)
abnormal osteoblast differentiation  (IAGP)
abnormal palatal shelf bone ossification  (IAGP)
abnormal palatine bone morphology  (IAGP)
abnormal perichondrium morphology  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal small intestine morphology  (IAGP)
abnormal smooth muscle morphology  (IAGP)
abnormal sternum morphology  (IAGP)
abnormal synchondrosis  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal visceral yolk sac mesenchyme morphology  (IAGP)
abnormal visceral yolk sac morphology  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
absent compact bone  (IAGP)
absent enteric neurons  (IAGP)
absent vitelline blood vessels  (IAGP)
aganglionic megacolon  (IAGP)
annular pancreas  (IAGP)
brachyphalangia  (IAGP)
chondrodystrophy  (IAGP)
decreased alkaline phosphatase activity  (IAGP)
decreased body height  (IAGP)
decreased body size  (IAGP)
decreased chondrocyte proliferation  (IAGP)
decreased fetal size  (IAGP)
decreased fetal weight  (IAGP)
decreased length of long bones  (IAGP)
decreased long bone epiphyseal plate size  (IAGP)
decreased osteoblast cell number  (IAGP)
decreased width of hypertrophic chondrocyte zone  (IAGP)
delayed endochondral bone ossification  (IAGP)
disorganized long bone epiphyseal plate  (IAGP)
disproportionate dwarf  (IAGP)
domed cranium  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
failure of initiation of embryo turning  (IAGP)
fused carpal bones  (IAGP)
increased long bone epiphyseal plate size  (IAGP)
median cleft palate  (IAGP)
megacolon  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality  (IAGP)
respiratory failure  (IAGP)
short femur  (IAGP)
short fibula  (IAGP)
short forelimb  (IAGP)
short humerus  (IAGP)
short limbs  (IAGP)
short mandible  (IAGP)
short ribs  (IAGP)
short scapula  (IAGP)
short snout  (IAGP)
short tail  (IAGP)
short tibia  (IAGP)
short ulna  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Interactions between Hedgehog proteins and their binding partners come into view. Beachy PA, etal., Genes Dev. 2010 Sep 15;24(18):2001-12.
2. Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice. Buller NV, etal., Gastroenterology. 2015 Jan;148(1):170-180.e6. doi: 10.1053/j.gastro.2014.10.006. Epub 2014 Oct 13.
3. Brachydactyly A-1 mutations restricted to the central region of the N-terminal active fragment of Indian Hedgehog. Byrnes AM, etal., Eur J Hum Genet. 2009 Sep;17(9):1112-20. doi: 10.1038/ejhg.2009.18. Epub 2009 Mar 11.
4. Ihh enhances differentiation of CFK-2 chondrocytic cells and antagonizes PTHrP-mediated activation of PKA. Deckelbaum RA, etal., J Cell Sci 2002 Jul 15;115(Pt 14):3015-25.
5. Mutation screening in candidate genes in four Chinese brachydactyly families. Dong S, etal., Ann Clin Lab Sci. 2015 Winter;45(1):94-9.
6. Mutations in IHH, encoding Indian hedgehog, cause brachydactyly type A-1. Gao B, etal., Nat Genet. 2001 Aug;28(4):386-8.
7. Correlation Between Hedgehog (Hh) Protein Family and Brain-Derived Neurotrophic Factor (BDNF) in Autism Spectrum Disorder (ASD). Halepoto DM, etal., J Coll Physicians Surg Pak. 2015 Dec;25(12):882-5. doi: 12.2015/JCPSP.882885.
8. Homozygous mutations in IHH cause acrocapitofemoral dysplasia, an autosomal recessive disorder with cone-shaped epiphyses in hands and hips. Hellemans J, etal., Am J Hum Genet. 2003 Apr;72(4):1040-6. Epub 2003 Mar 11.
9. Identification of a mutation in the Indian Hedgehog (IHH) gene causing brachydactyly type A1 and evidence for a third locus. Kirkpatrick TJ, etal., J Med Genet. 2003 Jan;40(1):42-4.
10. Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis. Klopocki E, etal., Am J Hum Genet. 2011 Jan 7;88(1):70-5. doi: 10.1016/j.ajhg.2010.11.006. Epub 2010 Dec 17.
11. A novel heterozygous mutation in the Indian hedgehog gene (IHH) is associated with brachydactyly type A1 in a Chinese family. Liu M, etal., J Hum Genet. 2006;51(8):727-31. Epub 2006 Jul 27.
12. Deletion of 1 amino acid in Indian hedgehog leads to brachydactylyA1. Lodder EM, etal., Am J Med Genet A. 2008 Aug 15;146A(16):2152-4. doi: 10.1002/ajmg.a.32441.
13. A novel mutation in the IHH gene causes brachydactyly type A1: a 95-year-old mystery resolved. McCready ME, etal., Hum Genet. 2002 Oct;111(4-5):368-75. Epub 2002 Sep 7.
14. MGDs mouse GO annotations MGD data from the GO Consortium
15. MGD IEA MGD IEA
16. Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies. Mimeault M and Batra SK, Pharmacol Rev. 2010 Sep;62(3):497-524.
17. Genetic contributions to the development of retinopathy of prematurity. Mohamed S, etal., Pediatr Res. 2009 Feb;65(2):193-7. doi: 10.1203/PDR.0b013e31818d1dbd.
18. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
19. Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni. Pereira TA, etal., Liver Int. 2013 Jan;33(1):149-61. doi: 10.1111/liv.12016. Epub 2012 Nov 1.
20. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
21. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
22. Mouse MP Annotation Import Pipeline RGD automated import pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. Brachydactyly type A1 associated with unusual radiological findings and a novel Arg158Cys mutation in the Indian hedgehog (IHH) gene. Stattin EL, etal., Eur J Med Genet. 2009 Sep-Oct;52(5):297-302. doi: 10.1016/j.ejmg.2009.05.008. Epub 2009 May 21.
26. Effect of ageing on healing of bilateral mandibular condyle fractures in a rat model. Tatsumi H, etal., Int J Oral Maxillofac Surg. 2014 Feb;43(2):185-93. doi: 10.1016/j.ijom.2013.07.742. Epub 2013 Aug 28.
27. Indian hedgehog in synovial fluid is a novel marker for early cartilage lesions in human knee joint. Zhang C, etal., Int J Mol Sci. 2014 Apr 28;15(5):7250-65. doi: 10.3390/ijms15057250.
28. FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling. Zhou S, etal., PLoS Genet. 2015 Jun 19;11(6):e1005214. doi: 10.1371/journal.pgen.1005214. eCollection 2015 Jun.
Additional References at PubMed
PMID:7589793   PMID:7590746   PMID:7720571   PMID:7916661   PMID:8595881   PMID:8662546   PMID:8662561   PMID:8849902   PMID:8937649   PMID:9009843   PMID:9053312   PMID:9079674  
PMID:9152005   PMID:9152011   PMID:9203584   PMID:9237688   PMID:9242425   PMID:9486541   PMID:9502734   PMID:9603738   PMID:9664687   PMID:9671585   PMID:9707582   PMID:9789035  
PMID:9811582   PMID:9811851   PMID:9853822   PMID:9858693   PMID:9885252   PMID:10049363   PMID:10050855   PMID:10072783   PMID:10208739   PMID:10208865   PMID:10213384   PMID:10349636  
PMID:10357934   PMID:10433909   PMID:10465785   PMID:10471501   PMID:10495271   PMID:10529434   PMID:10534616   PMID:10545953   PMID:10572046   PMID:10579908   PMID:10631175   PMID:10631181  
PMID:10742104   PMID:10804186   PMID:10821773   PMID:10842064   PMID:10861287   PMID:10926768   PMID:10981962   PMID:11042159   PMID:11044404   PMID:11076861   PMID:11118883   PMID:11133164  
PMID:11160153   PMID:11165481   PMID:11171337   PMID:11217851   PMID:11230154   PMID:11285272   PMID:11285276   PMID:11311154   PMID:11371614   PMID:11400162   PMID:11440720   PMID:11476578  
PMID:11517919   PMID:11566859   PMID:11572986   PMID:11702786   PMID:11713230   PMID:11714677   PMID:11735226   PMID:11748145   PMID:11784060   PMID:11784093   PMID:11792318   PMID:11807029  
PMID:11850178   PMID:11937493   PMID:11937494   PMID:11969258   PMID:11973269   PMID:11977981   PMID:11984876   PMID:12000792   PMID:12050144   PMID:12086466   PMID:12135917   PMID:12163410  
PMID:12192060   PMID:12195432   PMID:12217324   PMID:12351698   PMID:12361605   PMID:12379497   PMID:12385751   PMID:12399319   PMID:12399320   PMID:12414734   PMID:12421714   PMID:12435628  
PMID:12466851   PMID:12469909   PMID:12477932   PMID:12538525   PMID:12569124   PMID:12587916   PMID:12671688   PMID:12701101   PMID:12708796   PMID:12736220   PMID:12756179   PMID:12835312  
PMID:12895028   PMID:12902164   PMID:12917109   PMID:12917489   PMID:12944425   PMID:14516672   PMID:14522949   PMID:14623238   PMID:14668414   PMID:14673146   PMID:14722611   PMID:14745966  
PMID:14749384   PMID:14973297   PMID:14980515   PMID:14981086   PMID:14993235   PMID:15030764   PMID:15073150   PMID:15075292   PMID:15105374   PMID:15107405   PMID:15107406   PMID:15124025  
PMID:15132997   PMID:15151988   PMID:15175265   PMID:15177029   PMID:15238161   PMID:15305294   PMID:15316116   PMID:15355563   PMID:15465485   PMID:15509771   PMID:15537544   PMID:15563592  
PMID:15576404   PMID:15590741   PMID:15652702   PMID:15668393   PMID:15689378   PMID:15713743   PMID:15760903   PMID:15766752   PMID:15771625   PMID:15777636   PMID:15811134   PMID:15841179  
PMID:15866163   PMID:15866164   PMID:15878962   PMID:15923624   PMID:15936916   PMID:15951842   PMID:15963767   PMID:16026781   PMID:16141072   PMID:16141073   PMID:16141219   PMID:16168717  
PMID:16169709   PMID:16176985   PMID:16236767   PMID:16247775   PMID:16278811   PMID:16284117   PMID:16387856   PMID:16459298   PMID:16470614   PMID:16476422   PMID:16504022   PMID:16537363  
PMID:16537395   PMID:16543460   PMID:16598734   PMID:16602821   PMID:16618389   PMID:16618415   PMID:16707121   PMID:16815385   PMID:16818445   PMID:16829211   PMID:16857753   PMID:16877353  
PMID:16905129   PMID:16912273   PMID:16935278   PMID:16950122   PMID:16951680   PMID:16956603   PMID:17014841   PMID:17028112   PMID:17065231   PMID:17131407   PMID:17166921   PMID:17191253  
PMID:17199044   PMID:17199045   PMID:17204263   PMID:17257418   PMID:17299133   PMID:17317783   PMID:17336282   PMID:17336904   PMID:17343742   PMID:17359961   PMID:17360475   PMID:17392501  
PMID:17409191   PMID:17436279   PMID:17442891   PMID:17464332   PMID:17467682   PMID:17470636   PMID:17481601   PMID:17504940   PMID:17507416   PMID:17510210   PMID:17544391   PMID:17548469  
PMID:17555517   PMID:17555518   PMID:17576802   PMID:17660199   PMID:17670790   PMID:17698054   PMID:17707622   PMID:17764670   PMID:17881493   PMID:17952091   PMID:17967876   PMID:17983586  
PMID:18025304   PMID:18052755   PMID:18059015   PMID:18063705   PMID:18083924   PMID:18183793   PMID:18206867   PMID:18234177   PMID:18238902   PMID:18239353   PMID:18272352   PMID:18292212  
PMID:18297083   PMID:18424451   PMID:18429041   PMID:18434416   PMID:18446812   PMID:18456591   PMID:18514492   PMID:18539921   PMID:18582454   PMID:18582859   PMID:18597638   PMID:18632939  
PMID:18651652   PMID:18682398   PMID:18759297   PMID:18832069   PMID:19035497   PMID:19097194   PMID:19109233   PMID:19208343   PMID:19224984   PMID:19229324   PMID:19252479   PMID:19272384  
PMID:19273610   PMID:19356224   PMID:19369399   PMID:19378260   PMID:19389373   PMID:19389374   PMID:19419310   PMID:19443245   PMID:19445942   PMID:19501129   PMID:19536134   PMID:19557172  
PMID:19559697   PMID:19590010   PMID:19590577   PMID:19605502   PMID:19633173   PMID:19653325   PMID:19737917   PMID:19761883   PMID:19762422   PMID:19767744   PMID:19815519   PMID:19879143  
PMID:19906842   PMID:19906844   PMID:19948490   PMID:19956613   PMID:20007344   PMID:20024692   PMID:20056671   PMID:20059955   PMID:20123094   PMID:20179096   PMID:20185815   PMID:20200412  
PMID:20206616   PMID:20400693   PMID:20430747   PMID:20440000   PMID:20495570   PMID:20503373   PMID:20503377   PMID:20530870   PMID:20542037   PMID:20554972   PMID:20570969   PMID:20593419  
PMID:20660756   PMID:20682322   PMID:20692235   PMID:20799323   PMID:20843830   PMID:20920500   PMID:20951345   PMID:20978073   PMID:21185280   PMID:21246657   PMID:21267068   PMID:21297010  
PMID:21312270   PMID:21364421   PMID:21367821   PMID:21445361   PMID:21494559   PMID:21537345   PMID:21545794   PMID:21547909   PMID:21557453   PMID:21606205   PMID:21652647   PMID:21677750  
PMID:21681813   PMID:21683695   PMID:21731673   PMID:21750033   PMID:21750036   PMID:21793100   PMID:21795282   PMID:21873211   PMID:21873635   PMID:21911092   PMID:21953591   PMID:22016185  
PMID:22022457   PMID:22100262   PMID:22155508   PMID:22155527   PMID:22190639   PMID:22206015   PMID:22275805   PMID:22280990   PMID:22290230   PMID:22342522   PMID:22342532   PMID:22354840  
PMID:22402963   PMID:22427063   PMID:22493482   PMID:22507129   PMID:22547067   PMID:22843502   PMID:22869368   PMID:22879594   PMID:22885149   PMID:22916278   PMID:22936354   PMID:22936364  
PMID:23026747   PMID:23038774   PMID:23188710   PMID:23236128   PMID:23238123   PMID:23266329   PMID:23322385   PMID:23333759   PMID:23383321   PMID:23423383   PMID:23429478   PMID:23531410  
PMID:23554936   PMID:23652029   PMID:23665349   PMID:23717575   PMID:23792766   PMID:23871669   PMID:23872235   PMID:23891934   PMID:23913870   PMID:23955340   PMID:23994637   PMID:24000064  
PMID:24149372   PMID:24161523   PMID:24161848   PMID:24218567   PMID:24248941   PMID:24276541   PMID:24332809   PMID:24349082   PMID:24385915   PMID:24415953   PMID:24428864   PMID:24436304  
PMID:24551245   PMID:24553180   PMID:24604556   PMID:24753031   PMID:24757136   PMID:24821091   PMID:24844414   PMID:24852369   PMID:24859162   PMID:24862038   PMID:24887312   PMID:24909139  
PMID:24930703   PMID:24971735   PMID:25009997   PMID:25028519   PMID:25105964   PMID:25107907   PMID:25262822   PMID:25340332   PMID:25362352   PMID:25401279   PMID:25432534   PMID:25446537  
PMID:25564625   PMID:25581370   PMID:25587042   PMID:25600960   PMID:25631042   PMID:25639508   PMID:25736226   PMID:25761772   PMID:25808752   PMID:25842978   PMID:25917826   PMID:25959774  
PMID:25977369   PMID:26062940   PMID:26094741   PMID:26116392   PMID:26151572   PMID:26183770   PMID:26184908   PMID:26241389   PMID:26293299   PMID:26439398   PMID:26553654   PMID:26598695  
PMID:26620087   PMID:26794256   PMID:26859889   PMID:26890219   PMID:26918743   PMID:26932670   PMID:26963384   PMID:27019229   PMID:27160681   PMID:27299863   PMID:27320915   PMID:27370713  
PMID:27466187   PMID:27621061   PMID:27666725   PMID:27741240   PMID:27930311   PMID:28002442   PMID:28027321   PMID:28049832   PMID:28118357   PMID:28202523   PMID:28323137   PMID:28361052  
PMID:28432216   PMID:28696225   PMID:28749439   PMID:28846100   PMID:28943241   PMID:29031500   PMID:29107559   PMID:29222391   PMID:29244023   PMID:29276753   PMID:29282851   PMID:29287114  
PMID:29311969   PMID:29437042   PMID:29447948   PMID:29545125   PMID:29659575   PMID:29729398   PMID:29735531   PMID:29771958   PMID:29788357   PMID:29985470   PMID:30032718   PMID:30470823  
PMID:30504126   PMID:30801848   PMID:30853186   PMID:30854720   PMID:31201465   PMID:31202927   PMID:31382618   PMID:31442442   PMID:31449527   PMID:31550480   PMID:31845891   PMID:31847127  
PMID:32108165   PMID:32144802   PMID:32223017   PMID:32290615   PMID:32332736   PMID:32705199   PMID:32747435   PMID:32928505   PMID:32945847   PMID:33328171   PMID:33707608   PMID:33879790  
PMID:34292881   PMID:34331943   PMID:34407400   PMID:34423857   PMID:34732852   PMID:34929174   PMID:35140200   PMID:35383354   PMID:35472633   PMID:35689447   PMID:35765931   PMID:35835905  
PMID:35851381   PMID:35906245   PMID:36127325   PMID:36265686   PMID:36584300   PMID:36680774   PMID:36693323   PMID:36853961   PMID:37256934   PMID:37296099   PMID:37442233   PMID:37528140  
PMID:37683603   PMID:38058151   PMID:38234039   PMID:38346197   PMID:38466355   PMID:38472182   PMID:38540766   PMID:38694818   PMID:38836497   PMID:38968120   PMID:39012257   PMID:39503541  
PMID:39772668  


Genomics

Comparative Map Data
Ihh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,984,474 - 74,990,831 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,984,474 - 74,990,831 (-)EnsemblGRCm39 Ensembl
GRCm38174,945,315 - 74,951,672 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,945,315 - 74,951,672 (-)EnsemblGRCm38mm10GRCm38
MGSCv37174,991,892 - 74,998,225 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,878,525 - 74,884,858 (-)NCBIMGSCv36mm8
Celera175,500,289 - 75,506,631 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.55NCBI
IHH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,054,424 - 219,060,921 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,054,424 - 219,060,921 (-)EnsemblGRCh38hg38GRCh38
GRCh372219,919,146 - 219,925,643 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,627,390 - 219,633,433 (-)NCBINCBI36Build 36hg18NCBI36
Celera2213,688,833 - 213,694,930 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2211,773,140 - 211,779,240 (-)NCBIHuRef
CHM1_12219,926,506 - 219,932,606 (-)NCBICHM1_1
T2T-CHM13v2.02219,542,768 - 219,549,269 (-)NCBIT2T-CHM13v2.0
Ihh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,952,986 - 83,959,203 (-)NCBIGRCr8
mRatBN7.2976,504,315 - 76,510,532 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,504,315 - 76,510,532 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx984,948,807 - 84,955,041 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,077,709 - 90,083,943 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,463,912 - 88,470,146 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,208,223 - 82,214,440 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,208,223 - 82,214,440 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,977,484 - 81,983,701 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,287,115 - 74,293,332 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1974,435,304 - 74,439,783 (-)NCBI
Celera974,074,990 - 74,081,207 (-)NCBICelera
Cytogenetic Map9q33NCBI
Ihh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545314,376,718 - 14,381,747 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545314,376,665 - 14,382,536 (+)NCBIChiLan1.0ChiLan1.0
IHH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213121,685,363 - 121,691,496 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B121,700,328 - 121,706,388 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B106,312,472 - 106,319,124 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B224,905,488 - 224,917,887 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B224,906,271 - 224,911,506 (-)Ensemblpanpan1.1panPan2
IHH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,616,942 - 25,622,989 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,443,433 - 26,449,482 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03725,632,373 - 25,638,422 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3725,633,157 - 25,638,407 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,536,946 - 25,542,995 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,472,029 - 25,478,078 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,492,880 - 25,498,929 (-)NCBIUU_Cfam_GSD_1.0
Ihh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303175,131,886 - 175,137,781 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,474,665 - 1,480,568 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365691,474,693 - 1,480,562 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IHH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15121,083,753 - 121,090,121 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115121,083,750 - 121,090,548 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215134,122,714 - 134,129,084 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IHH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,960,296 - 104,966,596 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,960,120 - 104,966,585 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604094,431,690 - 94,438,180 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ihh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248235,959,448 - 5,964,769 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248235,959,329 - 5,965,584 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ihh
266 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:376
Count of miRNA genes:270
Interacting mature miRNAs:308
Transcripts:ENSMUST00000164097
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301714Vertcling_mvertical clinging (mouse)Not determined14293803176938167Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73615692107615830Mouse
18182931Metl1_mmetabolite locus 1, pyridoxate (mouse)14127539975275399Mouse
4141305Tgq9_mtriglyceride QTL 9 (mouse)Not determined5142160585421605Mouse
4141625Emo4_memotionality 4 (mouse)Not determined6807134586235027Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1301211Bbaa11_mB.burgdorferi-associated arthritis 11 (mouse)Not determined14888900682889210Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
14697705Stsl3b_mSalmonella typhimurium susceptibility locus 3b (mouse)17413915981777715Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170133533104139557Mouse
1357505Vtbt1_mvertebral trabecular bone trait 1 (mouse)Not determined15626621490266360Mouse
4141032Wbcc1_mwhite blood cell count 1 (mouse)Not determined4225966776259667Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15794135191941351Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15854919192549443Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15799197791992080Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
14747009Manh49_mmandible shape 49 (mouse)15794135191941351Mouse
1301616Yaa2_mY-linked autoimmune acceleration 2 (mouse)Not determined14685469080854839Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173266214108838414Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
10043965Obq24_mobesity QTL 24 (mouse)Not determined15089021684890216Mouse
1301430Cdcs2_mcytokine deficiency colitis susceptibility 2 (mouse)Not determined14889234582892485Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
1558717Ses1a_msalmonella enteritidis susceptibility 1a (mouse)Not determined15672692290727077Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173615692107615830Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1558905Gct7_mgranulosa cell tumorigenesis 7 (mouse)Not determined14734989481350013Mouse
4141393Mol2_mmodifier of LPS-response 2 (mouse)Not determined7162467978183144Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15854919192549443Mouse
1558822Vas1_mautoimmune vasitis resistance 1 (mouse)Not determined14888900682889210Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
1302119Cia15_mcollagen induced arthritis 15 (mouse)Not determined16588900688496101Mouse
1301670Ssta1_msusceptibility to Salmonella typhimurium antigens 1 (mouse)Not determined14594675579946882Mouse
1357741Nidd5k_mNidd5 on KK-A<y> (mouse)Not determined15597494889975057Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15799197791992080Mouse
1301225Sle7_msystematic lupus erythematosus susceptibility 7 (mouse)Not determined14685469080854839Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15799197791992080Mouse
4142467Wbcq1_mwhite blood cell quantitative locus 1 (mouse)Not determined15626621490266360Mouse
1301166Thypr2_mthymocyte proliferative response 2 (mouse)Not determined14127312475273271Mouse
1301933Insq6_minsulin QTL 6 (mouse)Not determined15672692290727077Mouse

Markers in Region
U85610  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38174,945,841 - 74,945,974UniSTSGRCm38
MGSCv37174,992,415 - 74,992,548UniSTSGRCm37
Celera175,500,812 - 75,500,945UniSTS
Cytogenetic Map1C3UniSTS
cM Map140.8UniSTS
Whitehead/MRC_RH11090.88UniSTS
Ihh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38174,946,676 - 74,948,324UniSTSGRCm38
MGSCv37174,993,250 - 74,994,898UniSTSGRCm37
Celera175,501,647 - 75,503,304UniSTS
Cytogenetic Map1C3UniSTS
cM Map140.8UniSTS
cM Map140.8UniSTS
cM Map140.8UniSTS
D1Mit7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38174,952,818 - 74,952,921UniSTSGRCm38
MGSCv37174,999,392 - 74,999,495UniSTSGRCm37
Celera175,507,798 - 75,507,921UniSTS
Cytogenetic Map1C3UniSTS
cM Map141.0UniSTS
Whitehead Genetic141.5UniSTS
Whitehead/MRC_RH11087.14UniSTS
Whitehead_YAC1 UniSTS
AI323361  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38174,945,353 - 74,945,439UniSTSGRCm38
MGSCv37174,991,927 - 74,992,013UniSTSGRCm37
Celera175,500,324 - 75,500,410UniSTS
Cytogenetic Map1C3UniSTS
cM Map140.8UniSTS
Whitehead/MRC_RH11092.36UniSTS
Ihh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1C3UniSTS
Ihh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38174,946,178 - 74,946,289UniSTSGRCm38
MGSCv37174,992,752 - 74,992,863UniSTSGRCm37
Celera175,501,149 - 75,501,260UniSTS
Cytogenetic Map1C3UniSTS
cM Map140.8UniSTS
Ihh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38174,951,252 - 74,951,476UniSTSGRCm38
MGSCv37174,997,826 - 74,998,050UniSTSGRCm37
Celera175,506,232 - 75,506,456UniSTS
Cytogenetic Map1C3UniSTS
cM Map140.8UniSTS
Ihh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1C3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000164097   ⟹   ENSMUSP00000128056
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,984,474 - 74,990,831 (-)Ensembl
GRCm38.p6 Ensembl174,945,315 - 74,951,672 (-)Ensembl
Ensembl Acc Id: ENSMUST00000189364
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,986,883 - 74,990,601 (-)Ensembl
GRCm38.p6 Ensembl174,947,724 - 74,951,442 (-)Ensembl
RefSeq Acc Id: NM_001313683   ⟹   NP_001300612
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39174,986,882 - 74,990,831 (-)NCBI
GRCm38174,947,723 - 74,951,672 (-)NCBI
Sequence:
RefSeq Acc Id: NM_010544   ⟹   NP_034674
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39174,984,474 - 74,990,831 (-)NCBI
GRCm38174,945,315 - 74,951,672 (-)NCBI
MGSCv37174,991,892 - 74,998,225 (-)RGD
Celera175,500,289 - 75,506,631 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034674   ⟸   NM_010544
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q61724 (UniProtKB/Swiss-Prot),   P97812 (UniProtKB/Swiss-Prot),   Q80XI9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001300612   ⟸   NM_001313683
- Peptide Label: isoform 2 precursor
- UniProtKB: Q80XI9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000128056   ⟸   ENSMUST00000164097
Protein Domains
Hint

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97812-F1-model_v2 AlphaFold P97812 1-411 view protein structure

Promoters
RGD ID:6874110
Promoter ID:EPDNEW_M506
Type:single initiation site
Name:Ihh_1
Description:Mus musculus Indian hedgehog , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38174,951,669 - 74,951,729EPDNEW
RGD ID:6817925
Promoter ID:MM_KWN:1208
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000006713,   UC007BNM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36174,997,436 - 74,997,936 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96533 AgrOrtholog
Ensembl Genes ENSMUSG00000006538 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000164097 ENTREZGENE
  ENSMUST00000164097.4 UniProtKB/Swiss-Prot
  ENSMUST00000189364 ENTREZGENE
Gene3D-CATH 3.30.1380.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hedgehog/Intein (Hint) domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Hedgehog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hedgehog_Hint UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hedgehog_sig/DD-Pept_Zn-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hedgehog_Signaling UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hedgehog_signalling_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hint_dom_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hint_dom_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hint_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Intein_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16147 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96533 ENTREZGENE
NCBI Gene 16147 ENTREZGENE
PANTHER HEDGEHOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11889:SF39 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HH_signal UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hint UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ihh PhenoGen
PIRSF Peptidase_C46 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS SONICHHOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE INTEIN_N_TER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HintC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HintN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55166 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt IHH_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q61724 ENTREZGENE
  Q80XI9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q61724 UniProtKB/Swiss-Prot