Nanp (N-acetylneuraminic acid phosphatase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Nanp (N-acetylneuraminic acid phosphatase) Mus musculus
Analyze
Symbol: Nanp
Name: N-acetylneuraminic acid phosphatase
RGD ID: 1551900
MGI Page MGI
Description: Predicted to enable N-acylneuraminate-9-phosphatase activity. Involved in CMP-N-acetylneuraminate biosynthetic process and N-acetylneuraminate metabolic process. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; liver; submandibular gland primordium; and telencephalon ventricular layer. Orthologous to human NANP (N-acetylneuraminic acid phosphatase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1600031M04Rik; A130094D17Rik; haloacid dehalogenase-like hydrolase domain containing 4; haloacid dehalogenase-like hydrolase domain-containing protein 4; Hdhd4; MGC103377; N-acetylneuraminate-9-phosphate phosphatase; N-acylneuraminate-9-phosphatase; neu5Ac-9-Pase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm18698   Gm6741  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392150,871,605 - 150,881,299 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2150,871,605 - 150,881,318 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382151,029,685 - 151,039,379 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2151,029,685 - 151,039,398 (-)Ensemblmm10GRCm38
MGSCv372150,855,421 - 150,865,115 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362150,721,138 - 150,730,796 (-)NCBIMGSCv36mm8
Celera2152,263,425 - 152,273,317 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.83NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11929971   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16237198  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:30382946   PMID:32325033   PMID:38355793  


Genomics

Comparative Map Data
Nanp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392150,871,605 - 150,881,299 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2150,871,605 - 150,881,318 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382151,029,685 - 151,039,379 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2151,029,685 - 151,039,398 (-)Ensemblmm10GRCm38
MGSCv372150,855,421 - 150,865,115 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362150,721,138 - 150,730,796 (-)NCBIMGSCv36mm8
Celera2152,263,425 - 152,273,317 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.83NCBI
NANP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382025,612,935 - 25,624,014 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2025,612,935 - 25,624,014 (-)Ensemblhg38GRCh38
GRCh372025,593,571 - 25,604,650 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362025,543,001 - 25,552,614 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342025,543,001 - 25,552,614NCBI
Celera2025,667,188 - 25,678,265 (-)NCBICelera
Cytogenetic Map20p11.21NCBI
HuRef2025,551,390 - 25,562,466 (-)NCBIHuRef
CHM1_12025,593,809 - 25,604,886 (-)NCBICHM1_1
T2T-CHM13v2.02025,678,481 - 25,689,560 (-)NCBIT2T-CHM13v2.0
Nanp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83160,289,269 - 160,302,001 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3160,288,830 - 160,302,002 (-)EnsemblGRCr8
mRatBN7.23139,826,549 - 139,841,655 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3139,826,549 - 139,841,648 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3143,725,380 - 143,738,147 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03152,309,149 - 152,321,917 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03150,057,374 - 150,070,106 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03146,800,018 - 146,812,988 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3146,800,019 - 146,812,989 (-)Ensemblrn6Rnor6.0
Rnor_5.03153,160,644 - 153,173,614 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43141,639,178 - 141,651,910 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3138,589,564 - 138,602,296 (-)NCBICelera
RGSC_v3.13141,544,751 - 141,557,483 (-)NCBI
Cytogenetic Map3q41NCBI
Nanp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,453,393 - 31,460,386 (-)Ensembl
ChiLan1.0NW_00495541531,453,393 - 31,460,147 (-)NCBIChiLan1.0ChiLan1.0
NANP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22126,497,333 - 26,507,875 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12026,494,167 - 26,504,699 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02025,566,464 - 25,576,960 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12025,970,274 - 25,981,685 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2025,970,274 - 25,981,685 (-)EnsemblpanPan2panpan1.1
NANP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1231,757,963 - 1,776,758 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,788,489 - 1,807,300 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0231,999,374 - 2,018,194 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl232,001,001 - 2,018,134 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1231,840,190 - 1,858,994 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0231,964,897 - 1,983,691 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0231,932,577 - 1,951,375 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nanp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640146,814,474 - 146,825,293 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936620234,964 - 246,803 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936620235,013 - 245,138 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NANP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1731,208,181 - 31,217,310 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11731,206,265 - 31,217,366 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21735,137,366 - 35,147,715 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103247037
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366612454,355 - 64,917 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nanp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462493941,567 - 51,634 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462493941,154 - 47,608 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nanp
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15130,711,551 - 130,726,376 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nanp
537 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:226
Count of miRNA genes:198
Interacting mature miRNAs:219
Transcripts:ENSMUST00000066640, ENSMUST00000140124
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135699221169699361Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148238204181755017Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150212221181755017Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143773445169117924Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150212221181755017Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150212221181755017Mouse
11353826Bdln10_mbody length 10 (mouse)2140441482174441482Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149236907181755017Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
4141033Wg2d_mweight gain in high growth mice 2d (mouse)Not determined143773445160303008Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132024159166024330Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2149988902181755017Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135699221169699361Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135699221169699361Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse
13504830Bacsq1_mbaculum shape QTL 1 (mouse)2145716184161016184Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142428347176428450Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133144911167145058Mouse
12801461Intim1_mintima modifier 1 (mouse)2142428347176428450Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133144911167145058Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135432544173449616Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135699221169699361Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143773445165665019Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148664893181755017Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2138966600172966729Mouse

Markers in Region
UniSTS:488753  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381791,236,791 - 91,238,055UniSTSGRCm38
MGSCv371791,636,131 - 91,637,395UniSTSGRCm37
Celera1795,634,403 - 95,635,683UniSTS
Cytogenetic Map17E5UniSTS
Cytogenetic Map2H1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000066640   ⟹   ENSMUSP00000063895
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2150,871,605 - 150,881,318 (-)Ensembl
GRCm38.p6 Ensembl2151,029,685 - 151,039,398 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140124
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2150,872,677 - 150,881,282 (-)Ensembl
GRCm38.p6 Ensembl2151,030,757 - 151,039,362 (-)Ensembl
RefSeq Acc Id: NM_026086   ⟹   NP_080362
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392150,871,605 - 150,881,299 (-)NCBI
GRCm382151,029,685 - 151,039,379 (-)ENTREZGENE
MGSCv372150,855,421 - 150,865,115 (-)RGD
Celera2152,263,425 - 152,273,317 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006500068   ⟹   XP_006500131
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392150,871,614 - 150,881,282 (-)NCBI
GRCm382151,029,694 - 151,039,362 (-)NCBI
Sequence:
RefSeq Acc Id: NP_080362   ⟸   NM_026086
- UniProtKB: Q9CPT3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006500131   ⟸   XM_006500068
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000063895   ⟸   ENSMUST00000066640

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CPT3-F1-model_v2 AlphaFold Q9CPT3 1-248 view protein structure

Promoters
RGD ID:6831896
Promoter ID:MM_KWN:32230
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK164971_A130094D17RIK,   OTTMUST00000037517,   OTTMUST00000037518,   OTTMUST00000037533
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362150,863,956 - 150,865,312 (-)MPROMDB
RGD ID:6879122
Promoter ID:EPDNEW_M3012
Type:multiple initiation site
Name:Nanp_1
Description:Mus musculus N-acetylneuraminic acid phosphatase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382151,039,362 - 151,039,422EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914561 AgrOrtholog
Ensembl Genes ENSMUSG00000053916 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000066640 ENTREZGENE
  ENSMUST00000066640.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1000 UniProtKB/Swiss-Prot
  Haloacid dehalogenase hydrolase-like domain UniProtKB/Swiss-Prot
InterPro HAD-like_hydrolase UniProtKB/Swiss-Prot
  HAD-like_sf UniProtKB/Swiss-Prot
  HAD-SF_hydro_IA UniProtKB/Swiss-Prot
  HAD-SF_hydro_IA_CTE7 UniProtKB/Swiss-Prot
  HAD_sf UniProtKB/Swiss-Prot
KEGG Report mmu:67311 UniProtKB/Swiss-Prot
MGD MGI:1914561 ENTREZGENE
NCBI Gene 67311 ENTREZGENE
PANTHER N-ACYLNEURAMINATE-9-PHOSPHATASE UniProtKB/Swiss-Prot
  N-ACYLNEURAMINATE-9-PHOSPHATASE UniProtKB/Swiss-Prot
Pfam Hydrolase UniProtKB/Swiss-Prot
PhenoGen Nanp PhenoGen
PRINTS HADHALOGNASE UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56784 UniProtKB/Swiss-Prot
UniProt NANP_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE