Npy2r (neuropeptide Y receptor Y2) - Rat Genome Database

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Gene: Npy2r (neuropeptide Y receptor Y2) Mus musculus
Analyze
Symbol: Npy2r
Name: neuropeptide Y receptor Y2
RGD ID: 1551786
MGI Page MGI
Description: Enables peptide YY receptor activity. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Located in non-motile cilium. Is active in cilium. Is expressed in central nervous system; dorsal root ganglion; eye; and metanephros. Human ortholog(s) of this gene implicated in Huntington's disease; morbid obesity; and obesity. Orthologous to human NPY2R (neuropeptide Y receptor Y2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC124241; MGC124242; MGC124244; neuropeptide Y receptor type 2; NPY-Y2 receptor; NPY2-R; Y2 receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39382,445,688 - 82,455,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl382,445,690 - 82,455,391 (-)EnsemblGRCm39 Ensembl
GRCm38382,538,383 - 82,548,989 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl382,538,383 - 82,548,084 (-)EnsemblGRCm38mm10GRCm38
MGSCv37382,342,305 - 82,352,007 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36382,624,310 - 82,634,013 (-)NCBIMGSCv36mm8
Celera382,557,426 - 82,567,083 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map336.49NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adipose tissue amount  (IAGP)
abnormal bone mineralization  (IAGP)
abnormal bone ossification  (IAGP)
abnormal bone structure  (IAGP)
abnormal circadian regulation of heart rate  (IAGP)
abnormal circulating glucose level  (IAGP)
abnormal circulating hormone level  (IAGP)
abnormal circulating insulin level  (IAGP)
abnormal eating behavior  (IAGP)
abnormal food intake  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal locomotor behavior  (IEA)
abnormal olfactory sensory neuron morphology  (IAGP)
abnormal osteoblast physiology  (IAGP)
abnormal postnatal subventricular zone morphology  (IAGP)
abnormal righting response  (IAGP)
abnormal rostral migratory stream morphology  (IAGP)
abnormal sleep duration  (IAGP)
abnormal spatial learning  (IAGP)
abnormal testosterone level  (IAGP)
abnormal trabecular bone morphology  (IAGP)
alcohol aversion  (IAGP)
decreased anxiety-related response  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased brown adipose tissue amount  (IAGP)
decreased circulating corticosterone level  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating LDL cholesterol level  (IAGP)
decreased circulating leptin level  (IAGP)
decreased circulating testosterone level  (IAGP)
decreased compact bone thickness  (IAGP)
decreased energy expenditure  (IAGP)
decreased epididymal fat pad weight  (IAGP)
decreased lean body mass  (IAGP)
decreased locomotor activity  (IAGP)
decreased mesenteric fat pad weight  (IAGP)
decreased neuronal precursor cell number  (IAGP)
decreased osteoclast cell number  (IAGP)
decreased response to leptin  (IAGP)
decreased testis weight  (IAGP)
decreased white adipose tissue amount  (IAGP)
decreased white adipose tissue mass  (IAGP)
enlarged spleen  (IEA)
female infertility  (IAGP)
impaired long-term object recognition memory  (IAGP)
increased body fat mass  (IAGP)
increased body weight  (IAGP)
increased bone mineralization  (IAGP)
increased bone ossification  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating corticosterone level  (IAGP)
increased circulating HDL cholesterol level  (IAGP)
increased circulating insulin-like growth factor I level  (IAGP)
increased circulating pancreatic peptide level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased fluid intake  (IAGP)
increased growth hormone level  (IAGP)
increased kidney weight  (IAGP)
increased liver triglyceride level  (IAGP)
increased liver weight  (IAGP)
increased oxygen consumption  (IAGP)
increased pancreas weight  (IAGP)
increased spleen weight  (IEA)
increased susceptibility to pharmacologically induced seizures  (IAGP)
increased susceptibility to weight gain  (IAGP)
increased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
increased total fat pad weight  (IAGP)
increased trabecular bone thickness  (IAGP)
increased trabecular bone volume  (IAGP)
increased triglyceride level  (IAGP)
increased white adipose tissue mass  (IAGP)
male infertility  (IAGP)
polyphagia  (IAGP)
prolonged QRS complex duration  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Expression of neuropeptide Y and its receptors Y1 and Y2 in the rat heart and its supplying autonomic and spinal sensory ganglia in experimentally induced diabetes. Chottova Dvorakova M, etal., Neuroscience. 2008 Feb 19;151(4):1016-28. doi: 10.1016/j.neuroscience.2007.07.069. Epub 2007 Dec 8.
2. Neuropeptide y and neuropeptide y y5 receptor interaction restores impaired growth potential of aging bone marrow stromal cells. Igura K, etal., Rejuvenation Res. 2011 Aug;14(4):393-403. doi: 10.1089/rej.2010.1129. Epub 2011 May 19.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Association of age at onset in Huntington disease with functional promoter variations in NPY and NPY2R. Kloster E, etal., J Mol Med (Berl). 2014 Feb;92(2):177-84.
5. Of mice and men: neuropeptide Y and its receptors are associated with atherosclerotic lesion burden and vulnerability. Li L, etal., J Cardiovasc Transl Res. 2011 Jun;4(3):351-62. doi: 10.1007/s12265-011-9271-5. Epub 2011 Apr 6.
6. Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men. Ma L, etal., Diabetes. 2005 May;54(5):1598-602.
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. Role of neuropeptide Y Y(1) and Y(2) receptors on behavioral despair in a rat model of depression with co-morbid anxiety. Morales-Medina JC, etal., Neuropharmacology. 2012 Jan;62(1):200-8. doi: 10.1016/j.neuropharm.2011.06.030. Epub 2011 Jul 23.
10. Neuropeptide Y suppresses absence seizures in a genetic rat model primarily through effects on Y receptors. Morris MJ, etal., Eur J Neurosci. 2007 Feb;25(4):1136-43.
11. Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y2 receptor activation. Nave H, etal., J Neuroimmunol. 2004 Oct;155(1-2):1-12.
12. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects. Torekov SS, etal., Diabetologia. 2006 Nov;49(11):2653-8. Epub 2006 Sep 22.
17. Overexpression of NPY and Y2 receptors in epileptic brain tissue: an endogenous neuroprotective mechanism in temporal lobe epilepsy? Vezzani A and Sperk G, Neuropeptides. 2004 Aug;38(4):245-52.
18. Difference of NPY and its receptor gene expressions between obesity and obesity-resistant rats in response to high-fat diet. Wang C, etal., Horm Metab Res. 2007 Apr;39(4):262-7.
Additional References at PubMed
PMID:8914576   PMID:9169155   PMID:9457684   PMID:9722158   PMID:10349636   PMID:10502824   PMID:10556287   PMID:10698177   PMID:10720571   PMID:11042159   PMID:11076861   PMID:11287094  
PMID:11353388   PMID:11579129   PMID:11786149   PMID:11927618   PMID:12000791   PMID:12031341   PMID:12072562   PMID:12126735   PMID:12167864   PMID:12453895   PMID:12477932   PMID:12576090  
PMID:12730369   PMID:12742262   PMID:12813010   PMID:12859347   PMID:12861009   PMID:14755515   PMID:14997009   PMID:15203244   PMID:15619538   PMID:15627497   PMID:15979311   PMID:16025447  
PMID:16100526   PMID:16141072   PMID:16141073   PMID:16160743   PMID:16190896   PMID:16198492   PMID:16216428   PMID:16319069   PMID:16364461   PMID:16380472   PMID:16529827   PMID:16602821  
PMID:16650144   PMID:16707424   PMID:16785231   PMID:16873543   PMID:16950139   PMID:16995815   PMID:16998904   PMID:17027162   PMID:17272395   PMID:17456788   PMID:17491016   PMID:17491022  
PMID:17603492   PMID:17615145   PMID:18003792   PMID:18085606   PMID:18221379   PMID:18287559   PMID:18305161   PMID:18357520   PMID:19000842   PMID:19084906   PMID:19121371   PMID:19182605  
PMID:19459152   PMID:19781771   PMID:19879900   PMID:19892938   PMID:19925840   PMID:19939871   PMID:20445054   PMID:20501433   PMID:20613867   PMID:20635164   PMID:20881101   PMID:21055451  
PMID:21267068   PMID:21452195   PMID:21546930   PMID:21586559   PMID:21816512   PMID:21873635   PMID:21923762   PMID:22289084   PMID:22723691   PMID:23011592   PMID:23283686   PMID:23395170  
PMID:24316073   PMID:24444822   PMID:24952961   PMID:24985894   PMID:25471570   PMID:25892222   PMID:26053317   PMID:26314208   PMID:26365505   PMID:26444586   PMID:27568567   PMID:28057538  
PMID:28106168   PMID:28154160   PMID:28476948   PMID:30201296   PMID:30857366   PMID:31126840   PMID:31152125   PMID:32101625   PMID:32259485   PMID:32561647   PMID:32568072   PMID:32709995  
PMID:33731450   PMID:34671097   PMID:34982958   PMID:35065713   PMID:35296859   PMID:36368466   PMID:37201523   PMID:37914931   PMID:38355793   PMID:38448588  


Genomics

Comparative Map Data
Npy2r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39382,445,688 - 82,455,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl382,445,690 - 82,455,391 (-)EnsemblGRCm39 Ensembl
GRCm38382,538,383 - 82,548,989 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl382,538,383 - 82,548,084 (-)EnsemblGRCm38mm10GRCm38
MGSCv37382,342,305 - 82,352,007 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36382,624,310 - 82,634,013 (-)NCBIMGSCv36mm8
Celera382,557,426 - 82,567,083 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map336.49NCBI
NPY2R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384155,173,723 - 155,217,076 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4155,208,636 - 155,217,078 (+)EnsemblGRCh38hg38GRCh38
GRCh374156,094,875 - 156,138,228 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364156,349,232 - 156,357,678 (+)NCBINCBI36Build 36hg18NCBI36
Build 344156,487,385 - 156,495,832NCBI
Celera4153,460,186 - 153,468,632 (+)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4151,868,438 - 151,876,885 (+)NCBIHuRef
CHM1_14156,107,896 - 156,116,343 (+)NCBICHM1_1
T2T-CHM13v2.04158,505,608 - 158,548,978 (+)NCBIT2T-CHM13v2.0
Npy2r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82170,200,027 - 170,210,286 (-)NCBIGRCr8
mRatBN7.22167,901,999 - 167,912,165 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2167,903,879 - 167,905,024 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2175,099,298 - 175,100,444 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02173,120,230 - 173,121,376 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02167,713,107 - 167,714,253 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02181,528,949 - 181,538,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,530,832 - 181,531,978 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02200,942,882 - 200,952,072 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42150,554,962 - 150,556,108 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12174,209,622 - 174,210,769 (-)NCBI
Celera2161,929,373 - 161,930,519 (-)NCBICelera
Cytogenetic Map2q34NCBI
Npy2r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547111,796,278 - 11,804,114 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547111,796,278 - 11,804,114 (-)NCBIChiLan1.0ChiLan1.0
NPY2R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23153,087,172 - 153,132,447 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14153,442,534 - 153,487,785 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04147,542,551 - 147,586,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14159,360,854 - 159,404,224 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4159,401,080 - 159,402,231 (+)Ensemblpanpan1.1panPan2
NPY2R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11552,790,136 - 52,797,785 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1552,794,671 - 52,795,818 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1553,131,265 - 53,141,184 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01553,475,002 - 53,484,515 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1553,481,383 - 53,484,128 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11552,727,621 - 52,737,421 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01552,836,294 - 52,846,610 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01553,149,800 - 53,159,345 (+)NCBIUU_Cfam_GSD_1.0
Npy2r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530137,606,621 - 37,615,131 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365761,932,870 - 1,938,703 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365761,932,526 - 1,939,560 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPY2R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl874,039,616 - 74,047,817 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1874,039,959 - 74,048,398 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2878,331,707 - 78,340,148 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NPY2R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17101,696,081 - 101,773,782 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7101,770,551 - 101,771,696 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603781,413,529 - 81,421,886 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Npy2r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248483,048,413 - 3,054,495 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248483,049,009 - 3,054,548 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:938
Count of miRNA genes:340
Interacting mature miRNAs:385
Transcripts:ENSMUST00000029633, ENSMUST00000098997, ENSMUST00000182181, ENSMUST00000182831
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35262550986625745Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35292318386923183Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34949500583495118Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35262550986625745Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34949500583495118Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35262550986625745Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4935758183357581Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse

Markers in Region
PMC124402P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38382,542,179 - 82,542,499UniSTSGRCm38
MGSCv37382,346,101 - 82,346,421UniSTSGRCm37
Celera382,561,222 - 82,561,542UniSTS
Cytogenetic Map3E3UniSTS
cM Map336.0UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000029633   ⟹   ENSMUSP00000029633
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl382,445,690 - 82,455,391 (-)Ensembl
GRCm38.p6 Ensembl382,538,383 - 82,548,084 (-)Ensembl
Ensembl Acc Id: ENSMUST00000098997   ⟹   ENSMUSP00000096595
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl382,445,693 - 82,455,359 (-)Ensembl
GRCm38.p6 Ensembl382,538,386 - 82,548,052 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182181   ⟹   ENSMUSP00000138559
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl382,447,256 - 82,455,267 (-)Ensembl
GRCm38.p6 Ensembl382,539,949 - 82,547,960 (-)Ensembl
Ensembl Acc Id: ENSMUST00000182831   ⟹   ENSMUSP00000138282
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl382,447,256 - 82,455,267 (-)Ensembl
GRCm38.p6 Ensembl382,539,949 - 82,547,960 (-)Ensembl
RefSeq Acc Id: NM_001205099   ⟹   NP_001192028
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39382,445,688 - 82,455,404 (-)NCBI
GRCm38382,538,383 - 82,548,085 (-)NCBI
Celera382,557,426 - 82,567,083 (-)ENTREZGENE
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001410443   ⟹   NP_001397372
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39382,445,688 - 82,455,404 (-)NCBI
RefSeq Acc Id: NM_001410444   ⟹   NP_001397373
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39382,445,688 - 82,455,404 (-)NCBI
RefSeq Acc Id: NM_001410445   ⟹   NP_001397374
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39382,445,688 - 82,455,404 (-)NCBI
RefSeq Acc Id: NM_008731   ⟹   NP_032757
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39382,445,688 - 82,455,404 (-)NCBI
GRCm38382,538,383 - 82,548,085 (-)NCBI
MGSCv37382,342,305 - 82,352,007 (-)RGD
Celera382,557,426 - 82,567,083 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032757   ⟸   NM_008731
- Peptide Label: isoform 1
- UniProtKB: F7C6W7 (UniProtKB/Swiss-Prot),   Q8BWV1 (UniProtKB/Swiss-Prot),   P97295 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001192028   ⟸   NM_001205099
- Peptide Label: isoform 2
- UniProtKB: Q3SWR9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000096595   ⟸   ENSMUST00000098997
Ensembl Acc Id: ENSMUSP00000138282   ⟸   ENSMUST00000182831
Ensembl Acc Id: ENSMUSP00000029633   ⟸   ENSMUST00000029633
Ensembl Acc Id: ENSMUSP00000138559   ⟸   ENSMUST00000182181
RefSeq Acc Id: NP_001397373   ⟸   NM_001410444
- Peptide Label: isoform 1
- UniProtKB: P97295 (UniProtKB/Swiss-Prot),   F7C6W7 (UniProtKB/Swiss-Prot),   Q8BWV1 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001397372   ⟸   NM_001410443
- Peptide Label: isoform 1
- UniProtKB: P97295 (UniProtKB/Swiss-Prot),   F7C6W7 (UniProtKB/Swiss-Prot),   Q8BWV1 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001397374   ⟸   NM_001410445
- Peptide Label: isoform 1
- UniProtKB: P97295 (UniProtKB/Swiss-Prot),   F7C6W7 (UniProtKB/Swiss-Prot),   Q8BWV1 (UniProtKB/Swiss-Prot)
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97295-F1-model_v2 AlphaFold P97295 1-381 view protein structure

Promoters
RGD ID:6880962
Promoter ID:EPDNEW_M3932
Type:multiple initiation site
Name:Npy2r_1
Description:Mus musculus neuropeptide Y receptor Y2 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38382,548,042 - 82,548,102EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108418 AgrOrtholog
Ensembl Genes ENSMUSG00000028004 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029633 ENTREZGENE
  ENSMUST00000029633.5 UniProtKB/Swiss-Prot
  ENSMUST00000098997 ENTREZGENE
  ENSMUST00000098997.5 UniProtKB/Swiss-Prot
  ENSMUST00000182181 ENTREZGENE
  ENSMUST00000182181.8 UniProtKB/TrEMBL
  ENSMUST00000182831 ENTREZGENE
  ENSMUST00000182831.2 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NPY2_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NPY_rcpt UniProtKB/Swiss-Prot
KEGG Report mmu:18167 UniProtKB/Swiss-Prot
MGD MGI:108418 ENTREZGENE
NCBI Gene 18167 ENTREZGENE
PANTHER NEUROPEPTIDE Y RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEUROPEPTIDE Y RECEPTOR TYPE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Npy2r PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NRPEPTIDEY2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NRPEPTIDEYR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F7C6W7 ENTREZGENE
  NPY2R_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3SWR9 ENTREZGENE, UniProtKB/TrEMBL
  Q8BWV1 ENTREZGENE
UniProt Secondary F7C6W7 UniProtKB/Swiss-Prot
  Q8BWV1 UniProtKB/Swiss-Prot