Plekhg2 (pleckstrin homology domain containing, family G (with RhoGef domain) member 2) - Rat Genome Database

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Gene: Plekhg2 (pleckstrin homology domain containing, family G (with RhoGef domain) member 2) Mus musculus
Analyze
Symbol: Plekhg2
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
RGD ID: 1551748
MGI Page MGI
Description: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Orthologous to human PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI194308; Cl; Clg; common site lymphoma/leukemia GEF; common site lymphoma/leukemia guanine nucleotide exchange factor; common-site lymphoma/leukemia GEF; Cslg; PH domain-containing family G member 2; pleckstrin homology domain-containing family G member 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,059,028 - 28,072,818 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl728,059,029 - 28,072,024 (-)EnsemblGRCm39 Ensembl
GRCm38728,359,603 - 28,372,681 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl728,359,604 - 28,372,599 (-)EnsemblGRCm38mm10GRCm38
MGSCv37729,144,623 - 29,157,681 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36728,068,364 - 28,081,337 (-)NCBIMGSCv36mm8
Celera722,921,244 - 22,934,300 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map716.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11839748   PMID:12466851   PMID:12477932   PMID:15449545   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:32203420   PMID:33220177   PMID:33492483   PMID:35203342   PMID:38355793  


Genomics

Comparative Map Data
Plekhg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,059,028 - 28,072,818 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl728,059,029 - 28,072,024 (-)EnsemblGRCm39 Ensembl
GRCm38728,359,603 - 28,372,681 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl728,359,604 - 28,372,599 (-)EnsemblGRCm38mm10GRCm38
MGSCv37729,144,623 - 29,157,681 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36728,068,364 - 28,081,337 (-)NCBIMGSCv36mm8
Celera722,921,244 - 22,934,300 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map716.71NCBI
PLEKHG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381939,412,669 - 39,428,415 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1939,412,669 - 39,428,415 (+)EnsemblGRCh38hg38GRCh38
GRCh371939,903,309 - 39,919,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361944,595,590 - 44,607,994 (+)NCBINCBI36Build 36hg18NCBI36
Build 341944,595,589 - 44,607,994NCBI
Celera1936,705,440 - 36,720,745 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1936,350,436 - 36,365,741 (+)NCBIHuRef
CHM1_11939,904,453 - 39,919,759 (+)NCBICHM1_1
T2T-CHM13v2.01942,216,931 - 42,232,678 (+)NCBIT2T-CHM13v2.0
Plekhg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8192,779,449 - 92,792,610 (-)NCBIGRCr8
mRatBN7.2183,651,902 - 83,665,063 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl183,647,748 - 83,665,063 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx189,062,265 - 89,075,285 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0197,520,760 - 97,533,774 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0190,818,135 - 90,831,155 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0185,386,492 - 85,399,699 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl185,386,470 - 85,399,699 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0186,601,556 - 86,614,808 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,469,392 - 83,482,599 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1183,547,718 - 83,561,049 (-)NCBI
Celera178,048,146 - 78,061,353 (-)NCBICelera
Cytogenetic Map1q21NCBI
Plekhg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955468138,542 - 149,686 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955468138,262 - 149,480 (-)NCBIChiLan1.0ChiLan1.0
PLEKHG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22045,705,299 - 45,720,896 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11947,578,615 - 47,591,473 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01936,510,855 - 36,526,623 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11945,058,556 - 45,071,940 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1945,058,562 - 45,071,940 (+)Ensemblpanpan1.1panPan2
PLEKHG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,800,620 - 113,811,478 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,800,305 - 113,810,683 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1113,204,323 - 113,215,885 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01114,401,596 - 114,413,158 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1114,402,845 - 114,413,070 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,960,344 - 113,970,953 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01113,593,351 - 113,604,693 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01114,588,209 - 114,598,821 (-)NCBIUU_Cfam_GSD_1.0
Plekhg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934913,828,956 - 13,839,964 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366612,257,068 - 2,268,716 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366612,257,097 - 2,268,301 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,069,564 - 48,079,672 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,069,532 - 48,080,001 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2643,879,976 - 43,890,625 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1634,017,152 - 34,031,559 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl634,018,684 - 34,031,200 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607312,038,395 - 12,052,809 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479412,742,905 - 12,754,662 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479412,740,657 - 12,754,281 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plekhg2
772 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1551
Count of miRNA genes:547
Interacting mature miRNAs:671
Transcripts:ENSMUST00000094644, ENSMUST00000119990, ENSMUST00000121085, ENSMUST00000128015, ENSMUST00000129145, ENSMUST00000144700, ENSMUST00000147362, ENSMUST00000147767, ENSMUST00000147887, ENSMUST00000152281
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
7394747asp3_maudiogenic seizure prone 3 (mouse)Not determined72730579836842367Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse

Markers in Region
RH135923  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38728,360,224 - 28,360,402UniSTSGRCm38
MGSCv37729,145,243 - 29,145,421UniSTSGRCm37
Celera722,921,864 - 22,922,042UniSTS
Cytogenetic Map7A3UniSTS
cM Map710.2UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001083912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001290542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011250408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030241941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC002327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC149606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF465238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LS482404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000094644   ⟹   ENSMUSP00000092228
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,059,029 - 28,071,658 (-)Ensembl
GRCm38.p6 Ensembl728,359,604 - 28,372,233 (-)Ensembl
Ensembl Acc Id: ENSMUST00000119990   ⟹   ENSMUSP00000112881
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,059,030 - 28,071,919 (-)Ensembl
GRCm38.p6 Ensembl728,359,605 - 28,372,494 (-)Ensembl
Ensembl Acc Id: ENSMUST00000121085   ⟹   ENSMUSP00000113449
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,059,030 - 28,070,999 (-)Ensembl
GRCm38.p6 Ensembl728,359,605 - 28,371,574 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128015
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,059,030 - 28,072,002 (-)Ensembl
GRCm38.p6 Ensembl728,359,605 - 28,372,577 (-)Ensembl
Ensembl Acc Id: ENSMUST00000129145
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,059,030 - 28,062,766 (-)Ensembl
GRCm38.p6 Ensembl728,359,605 - 28,363,341 (-)Ensembl
Ensembl Acc Id: ENSMUST00000144700   ⟹   ENSMUSP00000115651
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,060,517 - 28,072,024 (-)Ensembl
GRCm38.p6 Ensembl728,361,092 - 28,372,599 (-)Ensembl
Ensembl Acc Id: ENSMUST00000147362   ⟹   ENSMUSP00000118217
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,067,835 - 28,071,152 (-)Ensembl
GRCm38.p6 Ensembl728,368,410 - 28,371,727 (-)Ensembl
Ensembl Acc Id: ENSMUST00000147767
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,063,429 - 28,064,917 (-)Ensembl
GRCm38.p6 Ensembl728,364,004 - 28,365,492 (-)Ensembl
Ensembl Acc Id: ENSMUST00000147887   ⟹   ENSMUSP00000122050
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,069,841 - 28,070,933 (-)Ensembl
GRCm38.p6 Ensembl728,370,416 - 28,371,508 (-)Ensembl
Ensembl Acc Id: ENSMUST00000152281   ⟹   ENSMUSP00000117062
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,069,506 - 28,071,505 (-)Ensembl
GRCm38.p6 Ensembl728,370,081 - 28,372,080 (-)Ensembl
RefSeq Acc Id: NM_001083912   ⟹   NP_001077381
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,002 (-)NCBI
GRCm38728,359,604 - 28,372,662 (-)NCBI
MGSCv37729,144,623 - 29,157,681 (-)RGD
Celera722,921,244 - 22,934,300 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001290542   ⟹   NP_001277471
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,002 (-)NCBI
GRCm38728,359,604 - 28,372,662 (-)NCBI
Celera722,921,244 - 22,934,300 (-)NCBI
Sequence:
RefSeq Acc Id: NM_138752   ⟹   NP_620091
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,002 (-)NCBI
GRCm38728,359,604 - 28,372,662 (-)NCBI
MGSCv37729,144,623 - 29,157,681 (-)RGD
Celera722,921,244 - 22,934,300 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006539436   ⟹   XP_006539499
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,071,238 (-)NCBI
GRCm38728,359,603 - 28,371,815 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006539437   ⟹   XP_006539500
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,817 (-)NCBI
GRCm38728,359,603 - 28,372,681 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006539439   ⟹   XP_006539502
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,818 (-)NCBI
GRCm38728,359,603 - 28,372,681 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006539441   ⟹   XP_006539504
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,816 (-)NCBI
GRCm38728,359,603 - 28,372,681 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011250408   ⟹   XP_011248710
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,817 (-)NCBI
GRCm38728,359,603 - 28,372,681 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030241941   ⟹   XP_030097801
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,816 (-)NCBI
GRCm38728,359,603 - 28,372,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152530   ⟹   XP_036008423
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,816 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152531   ⟹   XP_036008424
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,816 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152532   ⟹   XP_036008425
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,813 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152533   ⟹   XP_036008426
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,102 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152534   ⟹   XP_036008427
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,059,028 - 28,072,813 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001077381 (Get FASTA)   NCBI Sequence Viewer  
  NP_001277471 (Get FASTA)   NCBI Sequence Viewer  
  NP_620091 (Get FASTA)   NCBI Sequence Viewer  
  XP_006539499 (Get FASTA)   NCBI Sequence Viewer  
  XP_006539500 (Get FASTA)   NCBI Sequence Viewer  
  XP_006539502 (Get FASTA)   NCBI Sequence Viewer  
  XP_006539504 (Get FASTA)   NCBI Sequence Viewer  
  XP_011248710 (Get FASTA)   NCBI Sequence Viewer  
  XP_030097801 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008423 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008424 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008425 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008426 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008427 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH25625 (Get FASTA)   NCBI Sequence Viewer  
  AAH52436 (Get FASTA)   NCBI Sequence Viewer  
  AAH56971 (Get FASTA)   NCBI Sequence Viewer  
  AAL93134 (Get FASTA)   NCBI Sequence Viewer  
  BAD21360 (Get FASTA)   NCBI Sequence Viewer  
  BAE25733 (Get FASTA)   NCBI Sequence Viewer  
  EDL24142 (Get FASTA)   NCBI Sequence Viewer  
  EDL24143 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000092228
  ENSMUSP00000092228.5
  ENSMUSP00000112881
  ENSMUSP00000112881.2
  ENSMUSP00000113449
  ENSMUSP00000113449.2
  ENSMUSP00000115651.2
  ENSMUSP00000117062.2
  ENSMUSP00000118217.2
  ENSMUSP00000122050.2
GenBank Protein Q6KAU7 (Get FASTA)   NCBI Sequence Viewer  
  SPT35781 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_620091   ⟸   NM_138752
- Peptide Label: isoform a
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   E9QKB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001077381   ⟸   NM_001083912
- Peptide Label: isoform b
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   G5E8T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006539500   ⟸   XM_006539437
- Peptide Label: isoform X2
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot),   D3Z5N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006539504   ⟸   XM_006539441
- Peptide Label: isoform X5
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539502   ⟸   XM_006539439
- Peptide Label: isoform X2
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot),   D3Z5N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006539499   ⟸   XM_006539436
- Peptide Label: isoform X1
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001277471   ⟸   NM_001290542
- Peptide Label: isoform b
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   G5E8T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011248710   ⟸   XM_011250408
- Peptide Label: isoform X1
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030097801   ⟸   XM_030241941
- Peptide Label: isoform X5
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000115651   ⟸   ENSMUST00000144700
Ensembl Acc Id: ENSMUSP00000112881   ⟸   ENSMUST00000119990
Ensembl Acc Id: ENSMUSP00000118217   ⟸   ENSMUST00000147362
Ensembl Acc Id: ENSMUSP00000122050   ⟸   ENSMUST00000147887
Ensembl Acc Id: ENSMUSP00000117062   ⟸   ENSMUST00000152281
Ensembl Acc Id: ENSMUSP00000113449   ⟸   ENSMUST00000121085
Ensembl Acc Id: ENSMUSP00000092228   ⟸   ENSMUST00000094644
RefSeq Acc Id: XP_036008423   ⟸   XM_036152530
- Peptide Label: isoform X5
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036008424   ⟸   XM_036152531
- Peptide Label: isoform X5
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036008427   ⟸   XM_036152534
- Peptide Label: isoform X6
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036008425   ⟸   XM_036152532
- Peptide Label: isoform X6
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036008426   ⟸   XM_036152533
- Peptide Label: isoform X6
- UniProtKB: Q8R4H6 (UniProtKB/Swiss-Prot),   Q7TS89 (UniProtKB/Swiss-Prot),   Q6PGK2 (UniProtKB/Swiss-Prot),   Q6KAU7 (UniProtKB/Swiss-Prot),   Q3UNL4 (UniProtKB/Swiss-Prot),   A0PJD9 (UniProtKB/Swiss-Prot)
Protein Domains
DH   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6KAU7-F1-model_v2 AlphaFold Q6KAU7 1-1340 view protein structure

Promoters
RGD ID:6892448
Promoter ID:EPDNEW_M9675
Type:initiation region
Name:Plekhg2_1
Description:Mus musculus pleckstrin homology domain containing, family Gmember 2 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38728,372,577 - 28,372,637EPDNEW
RGD ID:6841772
Promoter ID:MM_KWN:49635
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:UC009FYM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36729,148,831 - 29,149,331 (-)MPROMDB
RGD ID:6841770
Promoter ID:MM_KWN:49636
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung,   MEF_B6
Transcripts:OTTMUST00000079276
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36729,150,181 - 29,150,732 (-)MPROMDB
RGD ID:6848190
Promoter ID:MM_ACW:44024
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:PLEKHG2.LSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36729,152,796 - 29,153,296 (-)MPROMDB
RGD ID:6840865
Promoter ID:MM_KWN:49637
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001083912,   NM_138752,   OTTMUST00000079269,   OTTMUST00000079273,   OTTMUST00000079274,   OTTMUST00000082326,   UC009FYN.1,   UC009FYO.1,   UC009FYR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36729,156,381 - 29,158,057 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2141874 AgrOrtholog
Ensembl Genes ENSMUSG00000037552 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000094644 ENTREZGENE
  ENSMUST00000094644.11 UniProtKB/TrEMBL
  ENSMUST00000119990 ENTREZGENE
  ENSMUST00000119990.8 UniProtKB/TrEMBL
  ENSMUST00000121085 ENTREZGENE
  ENSMUST00000121085.8 UniProtKB/TrEMBL
  ENSMUST00000128015 ENTREZGENE
  ENSMUST00000144700.8 UniProtKB/TrEMBL
  ENSMUST00000147362.8 UniProtKB/TrEMBL
  ENSMUST00000147887.2 UniProtKB/TrEMBL
  ENSMUST00000152281.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_PLEKHG1_G2_G3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOS1_NGEF_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:101497 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2141874 ENTREZGENE
NCBI Gene 101497 ENTREZGENE
PANTHER FI17866P1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOS1_NGEF_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Plekhg2 PhenoGen
PROSITE DH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48065 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J1S3_MOUSE UniProtKB/TrEMBL
  A0PJD9 ENTREZGENE
  D3YY99_MOUSE UniProtKB/TrEMBL
  D3Z1B1_MOUSE UniProtKB/TrEMBL
  D3Z5N8 ENTREZGENE, UniProtKB/TrEMBL
  D6RFC7_MOUSE UniProtKB/TrEMBL
  E9QKB6 ENTREZGENE, UniProtKB/TrEMBL
  G5E8T4 ENTREZGENE, UniProtKB/TrEMBL
  PKHG2_MOUSE UniProtKB/Swiss-Prot
  Q3UNL4 ENTREZGENE
  Q6KAU7 ENTREZGENE
  Q6PGK2 ENTREZGENE
  Q7TS89 ENTREZGENE
  Q8R4H6 ENTREZGENE
UniProt Secondary A0PJD9 UniProtKB/Swiss-Prot
  Q3UNL4 UniProtKB/Swiss-Prot
  Q6PGK2 UniProtKB/Swiss-Prot
  Q7TS89 UniProtKB/Swiss-Prot
  Q8R4H6 UniProtKB/Swiss-Prot