Fkbp4 (FK506 binding protein 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Fkbp4 (FK506 binding protein 4) Mus musculus
Analyze
Symbol: Fkbp4
Name: FK506 binding protein 4
RGD ID: 1551632
MGI Page MGI
Description: Enables several functions, including heat shock protein binding activity; nuclear glucocorticoid receptor binding activity; and purine ribonucleoside triphosphate binding activity. Acts upstream of or within several processes, including androgen receptor signaling pathway; embryo implantation; and steroid hormone receptor complex assembly. Located in nucleus. Is expressed in epithelium of penile urethra; genital tubercle mesenchyme of male; pancreas epithelium; and prepuce of male. Used to study androgen insensitivity syndrome. Orthologous to human FKBP4 (FKBP prolyl isomerase 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; 59kDa; AL022792; AW208983; FK506-binding protein 4; FKBP-4; FKBP-5; FKBP-52; FKBP5; FKBP52; FKBP59; FKPB52; HBI; HSP-binding immunophilin; immunophilin FKBP52; p59; peptidyl-prolyl cis-trans isomerase FKBP4; PPIase FKBP4; rotamase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396128,407,066 - 128,415,619 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6128,406,698 - 128,415,640 (-)EnsemblGRCm39 Ensembl
GRCm386128,430,103 - 128,438,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6128,429,735 - 128,438,677 (-)EnsemblGRCm38mm10GRCm38
MGSCv376128,380,125 - 128,388,649 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366128,395,726 - 128,404,250 (-)NCBIMGSCv36mm8
Celera6130,106,929 - 130,115,449 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
2-nitrofluorene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
azoxystrobin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP)
cadmium sulfate  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP,ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (EXP)
chromium(6+)  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
dexamethasone  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dimethylarsinous acid  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glyphosate  (EXP,ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (ISO)
imidacloprid  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
levofloxacin  (ISO)
maneb  (EXP)
methamphetamine  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylseleninic acid  (ISO)
miconazole  (EXP)
N-nitrosodimethylamine  (ISO)
Nutlin-3  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phytoestrogen  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
pyrogallol  (EXP)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
T-2 toxin  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thiabendazole  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (EXP)
triptonide  (EXP)
trovafloxacin  (ISO)
valproic acid  (ISO)
zearalenone  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anogenital distance  (IAGP)
abnormal body wall morphology  (IEA)
abnormal cholesterol homeostasis  (IEA)
abnormal decidualization  (IAGP)
abnormal foreskin morphology  (IAGP)
abnormal luminal closure  (IAGP)
abnormal lymph node morphology  (IEA)
abnormal male genitalia morphology  (IEA)
abnormal male reproductive system morphology  (IAGP)
abnormal mammary gland development  (IAGP)
abnormal penis morphology  (IAGP)
abnormal placenta morphology  (IEA)
abnormal prostate gland development  (IAGP)
abnormal prostate gland morphology  (IAGP)
abnormal reproductive system morphology  (IAGP)
abnormal reproductive system physiology  (IAGP)
abnormal secondary sex determination  (IAGP)
abnormal seminal vesicle morphology  (IAGP)
abnormal skin morphology  (IEA)
abnormal sperm motility  (IAGP)
abnormal spleen morphology  (IEA)
abnormal testis morphology  (IAGP)
abnormal uterine receptivity  (IAGP)
abnormal vitreous body morphology  (IEA)
absent prostate gland anterior lobe  (IAGP)
absent testes  (IEA)
ambiguous external male genitalia  (IAGP)
asthenozoospermia  (IAGP)
cataract  (IEA)
decreased body weight  (IAGP)
decreased heart rate  (IEA)
decreased litter size  (IAGP)
decreased mean corpuscular volume  (IEA)
decreased seminal vesicle weight  (IAGP)
decreased superovulation rate  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
enlarged epididymis  (IEA)
enlarged lymph nodes  (IEA)
enlarged spleen  (IEA)
failure of embryo implantation  (IAGP)
female infertility  (IAGP)
hairpin sperm flagellum  (IAGP)
hypospadia  (IAGP)
impaired fertilization  (IAGP)
increased circulating testosterone level  (IAGP)
male infertility  (IAGP)
male pseudohermaphroditism  (IAGP)
no spontaneous movement  (IEA)
oligozoospermia  (IAGP)
penile hypospadia  (IAGP)
postnatal growth retardation  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
prolonged RR interval  (IEA)
reduced male fertility  (IAGP)
small epididymis  (IEA)
small penis  (IAGP)
small prostate gland anterior lobe  (IAGP)
small seminal vesicle  (IAGP)
small spleen  (IEA)
small testis  (IEA)
unilateral cryptorchism  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Chaperoning of glucocorticoid receptors. Pratt WB, etal., Handb Exp Pharmacol. 2006;(172):111-38.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Minireview: the intersection of steroid receptors with molecular chaperones: observations and questions. Smith DF and Toft DO, Mol Endocrinol. 2008 Oct;22(10):2229-40. Epub 2008 May 1.
9. Interactions of the mineralocorticoid receptor--within and without. Yang J and Fuller PJ, Mol Cell Endocrinol. 2012 Mar 24;350(2):196-205. doi: 10.1016/j.mce.2011.07.001. Epub 2011 Jul 18.
Additional References at PubMed
PMID:2592022   PMID:7493967   PMID:7671812   PMID:7693550   PMID:8341706   PMID:10349636   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11514552   PMID:11751894  
PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15528267   PMID:15761153   PMID:15782199   PMID:15831525   PMID:15840001   PMID:16141072   PMID:16141073  
PMID:16176985   PMID:16873445   PMID:17142810   PMID:17307907   PMID:17571166   PMID:17717070   PMID:17938211   PMID:18554416   PMID:18799693   PMID:18988805   PMID:19073255   PMID:19581287  
PMID:19945390   PMID:20038533   PMID:20427484   PMID:20605780   PMID:20713718   PMID:20796173   PMID:21730179   PMID:21873635   PMID:21935478   PMID:22416080   PMID:22641006   PMID:23676498  
PMID:23999428   PMID:24049110   PMID:24850415   PMID:24880616   PMID:25132599   PMID:26184908   PMID:27418439   PMID:30485818   PMID:30595499   PMID:30713523   PMID:32325033   PMID:32554809  
PMID:33554859   PMID:34072036   PMID:34133714   PMID:36114006   PMID:36293380   PMID:37248902   PMID:38355793  


Genomics

Comparative Map Data
Fkbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396128,407,066 - 128,415,619 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6128,406,698 - 128,415,640 (-)EnsemblGRCm39 Ensembl
GRCm386128,430,103 - 128,438,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6128,429,735 - 128,438,677 (-)EnsemblGRCm38mm10GRCm38
MGSCv376128,380,125 - 128,388,649 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366128,395,726 - 128,404,250 (-)NCBIMGSCv36mm8
Celera6130,106,929 - 130,115,449 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.0NCBI
FKBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38122,794,970 - 2,805,423 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl122,794,970 - 2,805,423 (+)EnsemblGRCh38hg38GRCh38
GRCh37122,904,136 - 2,914,589 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,774,414 - 2,783,385 (+)NCBINCBI36Build 36hg18NCBI36
Build 34122,774,413 - 2,783,383NCBI
Celera124,518,032 - 4,528,525 (+)NCBICelera
Cytogenetic Map12p13.33NCBI
HuRef122,762,075 - 2,772,155 (+)NCBIHuRef
CHM1_1122,903,346 - 2,913,827 (+)NCBICHM1_1
T2T-CHM13v2.0122,800,969 - 2,811,423 (+)NCBIT2T-CHM13v2.0
Fkbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84163,389,464 - 163,397,918 (-)NCBIGRCr8
mRatBN7.24161,703,379 - 161,711,833 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4161,703,379 - 161,711,833 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4167,932,996 - 167,941,451 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04163,715,934 - 163,724,389 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04162,349,970 - 162,358,425 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04161,748,993 - 161,757,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4161,748,993 - 161,757,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04226,954,534 - 226,962,988 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44165,448,027 - 165,456,481 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14165,694,232 - 165,699,379 (-)NCBI
Celera4150,404,805 - 150,413,259 (-)NCBICelera
Cytogenetic Map4q42NCBI
Fkbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542918,334,939 - 18,344,530 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542918,334,939 - 18,344,530 (+)NCBIChiLan1.0ChiLan1.0
FKBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2108,341,673 - 8,353,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1128,338,572 - 8,350,663 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0122,915,017 - 2,924,423 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1122,847,333 - 2,856,118 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl122,847,496 - 2,856,107 (+)Ensemblpanpan1.1panPan2
FKBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12741,950,087 - 41,959,136 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2741,950,509 - 41,959,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha274,725,111 - 4,734,083 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02742,308,268 - 42,317,245 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2742,308,301 - 42,317,761 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12742,249,772 - 42,258,704 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02742,219,464 - 42,228,431 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0274,084,855 - 4,093,764 (+)NCBIUU_Cfam_GSD_1.0
Fkbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945106,052,813 - 106,061,344 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366063,122,736 - 3,134,823 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366063,122,798 - 3,131,352 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl567,313,480 - 67,322,028 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1567,314,010 - 67,321,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2569,600,337 - 69,607,970 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FKBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,860,932 - 2,869,885 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,860,935 - 2,870,383 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660635,446,823 - 5,455,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fkbp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624860122,208 - 134,415 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624860122,728 - 135,258 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fkbp4
265 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1429
Count of miRNA genes:583
Interacting mature miRNAs:710
Transcripts:ENSMUST00000032508, ENSMUST00000139448, ENSMUST00000150387, ENSMUST00000151796
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128180868149588044Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4141611Btts_mbitterness tasting (mouse)Not determined6125333609134096586Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141064Ath37_matherosclerosis 37 (mouse)Not determined6116641858128495988Mouse
10412134Cmv4_mcytomegalovirus resistance 4 (mouse)Not determined6127815180136022150Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse

Markers in Region
AW208983  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386128,430,155 - 128,430,237UniSTSGRCm38
MGSCv376128,380,173 - 128,380,255UniSTSGRCm37
Celera6130,106,977 - 130,107,059UniSTS
Cytogenetic Map6F3UniSTS
Whitehead/MRC_RH61289.75UniSTS
RH125352  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386128,432,568 - 128,433,202UniSTSGRCm38
MGSCv376128,382,586 - 128,383,220UniSTSGRCm37
Celera6130,109,386 - 130,110,020UniSTS
Cytogenetic Map6F3UniSTS
UniSTS:235561  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386128,430,609 - 128,430,793UniSTSGRCm38
MGSCv376128,380,627 - 128,380,811UniSTSGRCm37
Celera6130,107,431 - 130,107,615UniSTS
Cytogenetic Map6F3UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY280598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X17069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X70887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000032508   ⟹   ENSMUSP00000032508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,407,066 - 128,415,640 (-)Ensembl
GRCm38.p6 Ensembl6128,430,103 - 128,438,677 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139448
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,406,698 - 128,415,640 (-)Ensembl
GRCm38.p6 Ensembl6128,429,735 - 128,438,677 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150387   ⟹   ENSMUSP00000119930
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,410,178 - 128,415,103 (-)Ensembl
GRCm38.p6 Ensembl6128,433,215 - 128,438,140 (-)Ensembl
Ensembl Acc Id: ENSMUST00000151796   ⟹   ENSMUSP00000122087
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6128,410,725 - 128,414,616 (-)Ensembl
GRCm38.p6 Ensembl6128,433,762 - 128,437,653 (-)Ensembl
RefSeq Acc Id: NM_010219   ⟹   NP_034349
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396128,407,066 - 128,415,619 (-)NCBI
GRCm386128,430,103 - 128,438,656 (-)NCBI
MGSCv376128,380,125 - 128,388,649 (-)RGD
Celera6130,106,929 - 130,115,449 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034349   ⟸   NM_010219
- UniProtKB: Q3TVC9 (UniProtKB/Swiss-Prot),   P30416 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000119930   ⟸   ENSMUST00000150387
Ensembl Acc Id: ENSMUSP00000032508   ⟸   ENSMUST00000032508
Ensembl Acc Id: ENSMUSP00000122087   ⟸   ENSMUST00000151796
Protein Domains
PPIase FKBP-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30416-F1-model_v2 AlphaFold P30416 1-458 view protein structure

Promoters
RGD ID:6847994
Promoter ID:MM_ACW:42827
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Liver
Transcripts:FKBP4.FSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366128,384,034 - 128,384,534 (-)MPROMDB
RGD ID:6839897
Promoter ID:MM_KWN:47791
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000082030,   OTTMUST00000060562,   OTTMUST00000060563,   OTTMUST00000060564,   OTTMUST00000060565,   UC009EDT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366128,386,791 - 128,388,902 (+)MPROMDB
RGD ID:6891142
Promoter ID:EPDNEW_M9022
Type:initiation region
Name:Fkbp4_1
Description:Mus musculus FK506 binding protein 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386128,438,656 - 128,438,716EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95543 AgrOrtholog
Ensembl Genes ENSMUSG00000030357 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032508 ENTREZGENE
  ENSMUST00000032508.11 UniProtKB/Swiss-Prot
  ENSMUST00000150387.8 UniProtKB/TrEMBL
  ENSMUST00000151796.3 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.50.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FKBP-type_PPIase UniProtKB/TrEMBL
  Immunophilin_FKBP-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PPIase_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PPIase_FKBP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_2 UniProtKB/Swiss-Prot
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14228 UniProtKB/Swiss-Prot
MGD MGI:95543 ENTREZGENE
NCBI Gene 14228 ENTREZGENE
PANTHER FK506-BINDING PROTEIN 59 UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYLPROLYL ISOMERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TETRATRICOPEPTIDE REPEAT DOMAIN 9 UniProtKB/Swiss-Prot
Pfam FKBP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_1 UniProtKB/Swiss-Prot
  TPR_2 UniProtKB/Swiss-Prot
PhenoGen Fkbp4 PhenoGen
PROSITE FKBP_PPIASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot
SMART TPR UniProtKB/Swiss-Prot
Superfamily-SCOP FKBP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F6S2D5_MOUSE UniProtKB/TrEMBL
  F7CAT1_MOUSE UniProtKB/TrEMBL
  FKBP4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TVC9 ENTREZGENE
  Q8CBS1_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TVC9 UniProtKB/Swiss-Prot