Aldh1l2 (aldehyde dehydrogenase 1 family, member L2) - Rat Genome Database

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Gene: Aldh1l2 (aldehyde dehydrogenase 1 family, member L2) Mus musculus
Analyze
Symbol: Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
RGD ID: 1551620
MGI Page MGI
Description: Enables formyltetrahydrofolate dehydrogenase activity. Involved in 10-formyltetrahydrofolate catabolic process; NADPH regeneration; and folic acid metabolic process. Acts upstream of or within with a positive effect on fatty acid beta-oxidation. Located in mitochondrion. Used to study metabolic dysfunction-associated steatotic liver disease. Orthologous to human ALDH1L2 (aldehyde dehydrogenase 1 family member L2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: aldehyde dehydrogenase 1L2; aldehyde dehydrogenase family 1 member L2; aldehyde dehydrogenase family 1 member L2, mitochondrial; D330038I09Rik; MGC19039; mitochondrial 10-formyltetrahydrofolate dehydrogenase; mitochondrial 10-FTHFDH; mtFDH; probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391083,320,386 - 83,370,008 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1083,323,314 - 83,370,004 (-)EnsemblGRCm39 Ensembl
GRCm381083,487,447 - 83,534,146 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1083,487,450 - 83,534,140 (-)EnsemblGRCm38mm10GRCm38
MGSCv371082,950,192 - 82,996,885 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361082,917,249 - 82,963,861 (-)NCBIMGSCv36mm8
Celera1085,474,860 - 85,521,640 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
10-formyltetrahydrofolic acid  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-D  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
5,6,7,8-tetrahydrofolic acid  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
amitrole  (ISO)
antimycin A  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzethonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
chromium trinitrate  (EXP)
clobetasol  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
dexamethasone  (EXP)
diclofenac  (EXP)
Didecyldimethylammonium  (ISO)
dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP)
fentin chloride  (ISO)
ferric oxide  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
fructose  (EXP)
gentamycin  (ISO)
glucose  (EXP)
hydroquinone  (ISO)
indometacin  (ISO)
iodide salt  (ISO)
isobutanol  (ISO)
ivermectin  (EXP)
L-methionine  (EXP)
lead diacetate  (EXP)
lucanthone  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
Mitotane  (ISO)
monosodium L-glutamate  (EXP)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodimethylamine  (ISO)
nickel sulfate  (ISO)
nitrofen  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paraquat  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (EXP,ISO)
resveratrol  (EXP)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
trovafloxacin  (EXP)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
mitochondrion  (HDA,ISO)
nucleoplasm  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12477932   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18614015   PMID:18971422   PMID:21677750  
PMID:21873635   PMID:27113764   PMID:30550785   PMID:31789450   PMID:33168096   PMID:36114006   PMID:37245210   PMID:37367944   PMID:37507016   PMID:38355793  


Genomics

Comparative Map Data
Aldh1l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391083,320,386 - 83,370,008 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1083,323,314 - 83,370,004 (-)EnsemblGRCm39 Ensembl
GRCm381083,487,447 - 83,534,146 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1083,487,450 - 83,534,140 (-)EnsemblGRCm38mm10GRCm38
MGSCv371082,950,192 - 82,996,885 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361082,917,249 - 82,963,861 (-)NCBIMGSCv36mm8
Celera1085,474,860 - 85,521,640 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.27NCBI
ALDH1L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812105,019,790 - 105,084,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12105,019,784 - 105,107,643 (-)EnsemblGRCh38hg38GRCh38
GRCh3712105,413,568 - 105,478,236 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612103,942,332 - 104,002,366 (-)NCBINCBI36Build 36hg18NCBI36
Celera12105,078,239 - 105,142,624 (-)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12102,472,652 - 102,538,019 (-)NCBIHuRef
CHM1_112105,379,314 - 105,443,992 (-)NCBICHM1_1
T2T-CHM13v2.012104,981,395 - 105,046,228 (-)NCBIT2T-CHM13v2.0
Aldh1l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8722,141,872 - 22,193,403 (+)NCBIGRCr8
mRatBN7.2720,254,246 - 20,305,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl720,254,233 - 20,305,776 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx722,226,671 - 22,277,861 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0724,389,426 - 24,440,621 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0724,166,438 - 24,217,632 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0726,375,866 - 26,425,838 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl726,375,866 - 26,425,108 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0726,506,321 - 26,555,206 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4722,398,067 - 22,450,381 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1722,418,181 - 22,469,924 (+)NCBI
Celera717,456,470 - 17,507,229 (+)NCBICelera
Cytogenetic Map7q13NCBI
Aldh1l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540539,387,527 - 39,437,322 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540539,387,949 - 39,437,282 (-)NCBIChiLan1.0ChiLan1.0
ALDH1L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210113,084,633 - 113,154,101 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112113,080,726 - 113,174,017 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012102,596,881 - 102,661,617 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112105,992,398 - 106,046,239 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12105,997,045 - 106,056,607 (-)Ensemblpanpan1.1panPan2
ALDH1L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11033,310,523 - 33,365,677 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1033,310,558 - 33,365,228 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1033,229,898 - 33,285,026 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01034,151,792 - 34,207,579 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1034,151,821 - 34,207,560 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11033,887,203 - 33,942,545 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01034,171,323 - 34,226,449 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01034,364,647 - 34,420,074 (+)NCBIUU_Cfam_GSD_1.0
Aldh1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494516,595,327 - 16,651,070 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364929,605,708 - 9,657,743 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364929,605,611 - 9,657,717 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH1L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl579,492,750 - 79,558,701 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1579,492,672 - 79,558,702 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2582,894,904 - 82,954,624 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH1L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111100,242,649 - 100,311,164 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11100,247,262 - 100,298,621 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037144,713,789 - 144,779,293 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh1l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247503,912,002 - 3,961,963 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247503,912,030 - 4,054,170 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aldh1l2
1507 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2129
Count of miRNA genes:753
Interacting mature miRNAs:1003
Transcripts:ENSMUST00000020497, ENSMUST00000125193, ENSMUST00000138858, ENSMUST00000141184, ENSMUST00000143793, ENSMUST00000146640, ENSMUST00000147381
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106684818792258673Mouse
12910789Pwgrq19_mpost-weaning growth rate QTL 19 (mouse)108282870092169056Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105109149085091639Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082078412116078412Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082309418116309657Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83017003117017136Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082309418116309657Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082309418116309657Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082309418116309657Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105109149085091639Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082392803116392952Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082309418116309657Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082309418116309657Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
4141382Ssrq4_mstress response QTL 4 (mouse)Not determined8249093890856102Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse

Markers in Region
UniSTS:236422  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381083,487,499 - 83,487,619UniSTSGRCm38
MGSCv371082,950,244 - 82,950,364UniSTSGRCm37
Celera1085,474,912 - 85,475,032UniSTS
Cytogenetic Map10C1UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_153543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC113014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ130150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000020497   ⟹   ENSMUSP00000020497
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1083,323,314 - 83,370,004 (-)Ensembl
GRCm38.p6 Ensembl1083,487,450 - 83,534,140 (-)Ensembl
Ensembl Acc Id: ENSMUST00000125193
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1083,339,856 - 83,349,584 (-)Ensembl
GRCm38.p6 Ensembl1083,503,992 - 83,513,720 (-)Ensembl
Ensembl Acc Id: ENSMUST00000138858
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1083,330,606 - 83,369,945 (-)Ensembl
GRCm38.p6 Ensembl1083,494,742 - 83,534,081 (-)Ensembl
Ensembl Acc Id: ENSMUST00000141184
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1083,330,604 - 83,333,366 (-)Ensembl
GRCm38.p6 Ensembl1083,494,740 - 83,497,502 (-)Ensembl
Ensembl Acc Id: ENSMUST00000143793
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1083,335,693 - 83,343,984 (-)Ensembl
GRCm38.p6 Ensembl1083,499,829 - 83,508,120 (-)Ensembl
Ensembl Acc Id: ENSMUST00000146640   ⟹   ENSMUSP00000117076
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1083,325,293 - 83,369,259 (-)Ensembl
GRCm38.p6 Ensembl1083,489,429 - 83,533,395 (-)Ensembl
Ensembl Acc Id: ENSMUST00000147381
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1083,329,201 - 83,331,881 (-)Ensembl
GRCm38.p6 Ensembl1083,493,337 - 83,496,017 (-)Ensembl
RefSeq Acc Id: NM_153543   ⟹   NP_705771
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,323,311 - 83,370,004 (-)NCBI
GRCm381083,487,447 - 83,534,140 (-)NCBI
MGSCv371082,950,192 - 82,996,885 (-)RGD
Celera1085,474,860 - 85,521,640 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011243403   ⟹   XP_011241705
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,320,386 - 83,370,008 (-)NCBI
GRCm381083,487,448 - 83,534,146 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155743   ⟹   XP_036011636
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391083,336,137 - 83,370,008 (-)NCBI
Sequence:
RefSeq Acc Id: NP_705771   ⟸   NM_153543
- UniProtKB: Q8K009 (UniProtKB/Swiss-Prot),   E9QLV8 (UniProtKB/Swiss-Prot),   D3Z6B9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241705   ⟸   XM_011243403
- Peptide Label: isoform X1
- UniProtKB: D3Z6B9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000020497   ⟸   ENSMUST00000020497
Ensembl Acc Id: ENSMUSP00000117076   ⟸   ENSMUST00000146640
RefSeq Acc Id: XP_036011636   ⟸   XM_036155743
- Peptide Label: isoform X2
Protein Domains
Carrier

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K009-F1-model_v2 AlphaFold Q8K009 1-923 view protein structure

Promoters
RGD ID:6818968
Promoter ID:MM_KWN:5124
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000061093
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361082,996,126 - 82,996,702 (-)MPROMDB
RGD ID:6818970
Promoter ID:MM_KWN:5125
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:NM_153543,   OTTMUST00000061150
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361082,996,479 - 82,996,979 (-)MPROMDB
RGD ID:8672908
Promoter ID:EPDNEW_M14471
Type:initiation region
Name:Aldh1l2_1
Description:Mus musculus aldehyde dehydrogenase 1 family, member L2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381083,534,102 - 83,534,162EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444680 AgrOrtholog
Ensembl Genes ENSMUSG00000020256 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020497 ENTREZGENE
  ENSMUST00000020497.14 UniProtKB/Swiss-Prot
  ENSMUST00000146640.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1200.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.25.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formyl transferase, N-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 10_FTHF_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACP-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH/histidinol_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formyl_trans_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formyl_trans_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formyl_transf_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formyl_transf_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formyl_transferase-like_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GART_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PP-bd_ACP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ppantetheine_attach_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:216188 UniProtKB/Swiss-Prot
MGD MGI:2444680 ENTREZGENE
NCBI Gene Aldh1l2 ENTREZGENE
PANTHER ALDEHYDE DEHYDROGENASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITOCHONDRIAL 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formyl_trans_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formyl_trans_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PP-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aldh1l2 PhenoGen
PIRSF 10-FTHFDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CARRIER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GART UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHOPANTETHEINE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47336 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50486 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53328 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AL1L2_MOUSE UniProtKB/Swiss-Prot
  D3Z6B9 ENTREZGENE, UniProtKB/TrEMBL
  E9QLV8 ENTREZGENE
  Q8K009 ENTREZGENE
UniProt Secondary E9QLV8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Aldh1l2  aldehyde dehydrogenase 1 family, member L2  D330038I09Rik  RIKEN cDNA D330038I09 gene  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 D330038I09Rik  RIKEN cDNA D330038I09 gene  Aldh1l2  aldehyde dehydrogenase 1 family, member L2  Symbol and/or name change 5135510 APPROVED